Cell CycleCheckpoint Kinase 2Cell Cycle ProteinsGenes, cdcDNA DamageMitosisProtein-Serine-Threonine KinasesCell Cycle CheckpointsG2 PhaseS PhaseM Phase Cell Cycle CheckpointsProtein KinasesAtaxia Telangiectasia Mutated ProteinsDNA ReplicationSpindle ApparatusS Phase Cell Cycle CheckpointsHydroxyureaSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe ProteinsNuclear ProteinsSchizosaccharomycesG2 Phase Cell Cycle CheckpointsG1 PhaseSaccharomyces cerevisiaeKinetochorescdc25 PhosphatasesDNA-Binding ProteinsPhosphorylationNocodazoleDNA RepairFungal ProteinsCDC2 Protein KinaseTumor Suppressor ProteinsMutationCyclin BTumor Suppressor Protein p53DNA, FungalAnaphaseMethyl MethanesulfonateIntracellular Signaling Peptides and ProteinsSignal TransductionUltraviolet RaysGenomic InstabilityHeLa CellsCell DivisionSecurinCdc20 ProteinsCyclin-Dependent Kinase Inhibitor p21Gamma RaysCell Line, TumorChromosome SegregationApoptosisSaccharomycetalesModels, BiologicalCyclinsGenes, FungalCyclin-Dependent Kinase 2Molecular Sequence DataGene Expression Regulation, FungalExodeoxyribonucleasesCell LineChromosomal Proteins, Non-HistoneCyclin B1Ubiquitin-Protein Ligase ComplexesAnaphase-Promoting Complex-CyclosomeNucleic Acid Synthesis InhibitorsHistonesG1 Phase Cell Cycle CheckpointsRepressor ProteinsMetaphaseProtein BindingReplication Protein AAmino Acid SequenceFlow CytometryRadiation, IonizingGene DeletionAurora KinasesReplication Protein CDNA Breaks, Double-StrandedChromatinMad2 ProteinsHCT116 CellsDNAChromosomal InstabilityTelomereCyclin-Dependent KinasesCarrier ProteinsCell ProliferationRetinoblastoma ProteinCaffeineCell NucleusDNA HelicasesEnzyme ActivationRNA, Small InterferingMicrotubulesMeiosisTranscription FactorsDose-Response Relationship, RadiationCalcium-Binding ProteinsEnzyme Inhibitors