Checkpoint Kinase 2Cell Cycle ProteinsGenes, cdcDNA DamageProtein-Serine-Threonine KinasesG2 PhaseProtein KinasesMitosisAtaxia Telangiectasia Mutated ProteinsCell CycleS PhaseCell Cycle CheckpointsHydroxyureaDNA ReplicationSaccharomyces cerevisiae ProteinsS Phase Cell Cycle CheckpointsM Phase Cell Cycle CheckpointsSpindle ApparatusSchizosaccharomyces pombe ProteinsSaccharomyces cerevisiaeSchizosaccharomycescdc25 PhosphatasesNuclear ProteinsKinetochoresFungal ProteinsDNA-Binding ProteinsDNA, FungalDNA RepairPhosphorylationNocodazoleMethyl MethanesulfonateIntracellular Signaling Peptides and ProteinsSecurinTumor Suppressor ProteinsAnaphaseMutationUltraviolet RaysG1 PhaseG2 Phase Cell Cycle CheckpointsGenomic InstabilityCDC2 Protein KinaseCyclin BTumor Suppressor Protein p53ExodeoxyribonucleasesSaccharomycetalesMad2 ProteinsSignal TransductionGenes, FungalGamma RaysGene Expression Regulation, FungalHeLa CellsReplication Protein CReplication Protein ACdc20 ProteinsNucleic Acid Synthesis InhibitorsChromosomal Proteins, Non-HistoneModels, BiologicalChromosome SegregationGene DeletionTelomereCell Line, TumorCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase 2HCT116 CellsCaffeineRepressor ProteinsCyclin-Dependent KinasesDNA HelicasesRibonucleotide ReductasesMolecular Sequence DataHistonesChromosomes, FungalEpistasis, GeneticGenome, FungalChromatinStaurosporineProtein BindingAmino Acid SequenceDose-Response Relationship, RadiationCell DivisionCell LineRecombination, GeneticMetaphaseRadiation, IonizingAnaphase-Promoting Complex-CyclosomeUbiquitin-Protein Ligase ComplexesAurora KinasesCarrier ProteinsDNA Breaks, Double-StrandedApoptosisChromosomal InstabilityEnzyme ActivationFlow CytometryAllelesDNAPhosphoproteinsCyclin B1Enzyme InhibitorsCalcium-Binding ProteinsPhenotype