• Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons in the central nervous system. (dovepress.com)
  • This review will summarize the updated research progress on APOE functions and its role in Alzheimer's disease, Parkinson's disease, cardiovascular diseases, multiple sclerosis, type 2 diabetes mellitus, Type III hyperlipoproteinemia, vascular dementia, and ischemic stroke. (dovepress.com)
  • The apolipoprotein E (APOE) gene is located on chromosome 19 and encodes a glycoprotein that is 299 amino acids long. (dovepress.com)
  • 2 In the blood, APOE protein could interact with lipids, resulting in lipoproteins, including very-low-density lipoproteins (VLDL). (dovepress.com)
  • APOE is also involved in the formation of chylomicrons and VLDL and affects the activity of other lipid metabolism-associated proteins and enzymes, such as hepatic lipase and lipoprotein lipase. (dovepress.com)
  • 3 In this review, we discuss the biological functions of human APOE and its role in Alzheimer's disease (AD), Parkinson's disease (PD), cardiovascular diseases (CVD), multiple sclerosis (MS), type 2 diabetes mellitus (T2DM), vascular dementia (VD), and ischemic (occlusive) stroke (IS). (dovepress.com)
  • Aim: We aimed to investigate the expression of monocyte chemoattractant proteins (MCPs) and their cognate receptor CC chemokine receptor 2 (CCR2) in aortas of apolipoprotein E-null (apoE -/- ) mice during atherogenesis as well as the possible transcription pathway involved in the early induction of MCP-1 in vascular smooth muscle cells (VSMCs) in vivo . (go.jp)
  • Apolipoprotein E (ApoE), an important mediator of lipid transportation in plasma and the nervous system, plays a large role in diseases such as atherosclerosis and Alzheimer's. (diva-portal.org)
  • Small-angle neutron scattering shows that the ApoE containing lipid particles form elliptical disc-like structures, similar in shape but larger than nascent or discoidal HDL based on Apolipoprotein A1 (ApoA1). (diva-portal.org)
  • Conflicting results also concern the frequency of the association between the two protein misfolding disorders and the issue of whether the apolipoprotein E gene ( APOE ) and the prion protein gene ( PRNP ), the major modifiers of Aβ- and PrP-related pathologies, also have a pathogenic role in other proteinopathies, including tau neurofibrillary degeneration. (biomedcentral.com)
  • II) the influence of APOE genotype on CJD pathology, and (III) the effect of AD/PART co-pathology on the clinical CJD phenotype. (biomedcentral.com)
  • E1/E2 heterodimer binds host apolipoproteins such as APOB and APOE thereby forming a lipo-viro-particle (LVP) (PubMed:25122793, PubMed:29695434, PubMed:24838241). (proteopedia.org)
  • The interaction between E2 and host apolipoprotein E/APOE allows the proper assembly, maturation and infectivity of the viral particles (PubMed:25122793, PubMed:29695434). (proteopedia.org)
  • Self-assembly of HEK cell-secreted ApoE particles resembles ApoE enrichment of lipoproteins as a ligand for the LDL receptor-related protein. (uchicago.edu)
  • Here, we report that apolipoprotein A-I (ApoA-I), the major component of high-density lipoprotein (HDL), is upregulated in PCa based on both bioinformatics and experimental evidence. (bvsalud.org)
  • Activated protein C resistance and low molecular weight lipoprotein (a): dual pathogens for atherothrombosis? (mcmaster.ca)
  • Lipoprotein association of human apolipoprotein E/A-I chimeras. (uchicago.edu)
  • Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. (uchicago.edu)
  • Characterization of lipoprotein produced by the perfused rhesus monkey liver. (uchicago.edu)
  • Relationships of plasma and hepatic variables with rates of plasma low-density lipoprotein apolipoprotein B metabolism in baboons fed low- and high-fat diets. (uchicago.edu)
  • Each lipoprotein is characterized by its lipid composition and by the type and number of apolipoproteins it possesses. (medscape.com)
  • these apolipoproteins have lipid-soluble segments, the beta apolipoproteins, which remain part of the lipoprotein throughout its metabolism. (medscape.com)
  • Its main function is inhibition of cholesteryl ester transfer protein (CETP), probably by altering the electric charge of HDL molecules. (wikipedia.org)
  • Characterization of cholesteryl ester transfer protein inhibitor from plasma of baboons (Papio sp. (uchicago.edu)
  • In this sense Gr-VHDL fraction has 98.6% of hemolymphatic proteins, and 89.3% of lipids presents in the hemolymph. (scirp.org)
  • Both lipoproteic fractions possess phospholipids such as majority lipids (phosphatidylcholine and phosphatidylethanolamine) and 18:1, 16:0, 18:2 and 18:0 as the major fatty acids. (scirp.org)
  • Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication due to their ability to transfer bioactive lipids, proteins and different species of RNA into cells. (selectbiosciences.com)
  • Influence of dietary lipids on hepatic mRNA levels of proteins regulating plasma lipoproteins in baboons with high and low levels of large high density lipoproteins. (uchicago.edu)
  • Native membrane derived polymer-supported lipid bilayers (nSLBs) are poised to bridge the gap between live cell experiments and traditional model membrane architectures that by offering a combination of accessibility by surface sensitive analytical instrumentation and a composition which more closely resembles cellular membranes by displaying a diversity of endogenous membrane proteins, lipids, and carbohydrates. (lu.se)
  • Due to the lack of detergent solubilization and reconstitution steps, the nSLBs created using this approach contain essentially all of the native lipids, as well as the membrane-associated proteins and carbohydrates from the donor membrane. (lu.se)
  • PADs cause post-translational deimination of proteins by converting arginine into citrulline (citrullination/deimination), resulting in structural and functional changes in target proteins. (westminster.ac.uk)
  • The results showed that among the top 20% of overexpressed genes, gene families related to protein synthesis and structural components were much more abundant in S . leurokolos compared to A . longirostris . (prelekara.sk)
  • Finally, genes related to structural proteins, immune proteins and protectants were overexpressed or positively selected. (prelekara.sk)
  • Kringles are autonomous structural domains, found throughout the blood clotting and fibrinolytic proteins. (embl.de)
  • The low metastability of preb-HDL has made a structural/functional characterization of this particle difficult. (pnnl.gov)
  • Participates in the viral particle production as a result of its interaction with the non-structural protein 5A (By similarity). (proteopedia.org)
  • Apolipoprotein E structural requirements for the formation of SDS-stable complexes with beta-amyloid-(1-40): the role of salt bridges. (uchicago.edu)
  • Blom A. M. , Mörgelin M., Öyen M., Jarvet J. and Fries E. (1999) Structural characterization of inter-a-inhibitor - evidence for an extended shape. (lu.se)
  • Blom A. M. , Kask L. and B. Dahlbäck (2001) Structural requirements for the complement regulatory activities of C4b-binding protein. (lu.se)
  • Kask L., Hillarp A., Ramesh B., Dahlbäck B., and Blom A. M. (2002) Structural requirements for the intra-cellular subunit polymerization of the complement inhibitor C4b-binding protein. (lu.se)
  • Apolipoprotein C-I is a protein component of lipoproteins that in humans is encoded by the APOC1 gene. (wikipedia.org)
  • The protein encoded by this gene is a member of the apolipoprotein C family. (wikipedia.org)
  • A pseudogene of this gene is located 4 kb downstream from the apoC-I gene in the same orientation on chromosome 19, where both reside within an apolipoprotein gene cluster. (wikipedia.org)
  • Apolipoprotein gene cluster on chromosome 19. (wikipedia.org)
  • Analysis of two highly expressed genes from Chlorella virus PBCV-1: Protein characterization and the DNA sequences of the major capsid protein gene and the early/late 33-kDa protein gene. (uml.edu)
  • 1995. Transcriptional induction of pim-1 protein kinase gene expression by interferon gamma and posttranscriptional effects on costimulation with steel factor. . (oregonstate.edu)
  • They include sporadic cases of unknown origin, a genetic form linked to mutations in the prion protein gene, PRNP , and an infectious form acquired through medical procedures or contaminated food. (biomedcentral.com)
  • Although possession of the ε4 allele of the apolipoprotein E gene appears to be an important biological marker for Alzheimer's disease (AD) susceptibility, strong evidence indicates that at least one additional risk gene exists on chromosome 12. (bmj.com)
  • The protein encoded by this gene lacks the zinc binding activity of other family members. (antibodies-online.com)
  • Two transcript variants encoding different isoforms have been found for this gene. (antibodies-online.com)
  • It is caused by a homozygous autosomal recessive mutation in the gene for microsomal triglyceride transfer protein (MTP). (medscape.com)
  • FHBL is caused by an autosomal, codominant mutation in the gene for apoB ( APOB ), which is carried on chromosome 2. (medscape.com)
  • Ankyrins link integral membrane proteins to the spectrin-based membrane skeleton. (dana-farber.org)
  • Hereditary defects in membrane skeleton proteins. (dana-farber.org)
  • This indicates that AE1 and probably other integral membrane proteins have a 'lipid-anchoring' function. (dana-farber.org)
  • The SNARE complex assembles from vesicular Synaptobrevin-2 as well as Syntaxin-1 and SNAP25 both anchored to the presynaptic membrane. (nature.com)
  • Fusion of synaptic vesicles with the presynaptic membrane occurs in the presence of the NSF (N-ethylmaleimide-sensitive-factor) / α-SNAP (α-soluble NSF attachment protein) disassembly machinery. (nature.com)
  • While many studies have been focused on the membrane structure, the dynamics of such systems are crucial for the function of the membrane including membrane bound proteins. (lu.se)
  • Old World monkeys and great apes other than humans have been shown to have two active genes. (wikipedia.org)
  • Click on genes, proteins and metabolites below to link to respective articles. (wikipedia.org)
  • Many of these genes encode proteins (e.g., enzymes involved in protein glycosylation) rarely associated with viruses. (uml.edu)
  • Expression and Activity of Methionine Cycle Genes Are Altered Following Folate and Vitamin E Deficiency Under Oxidative Challenge: Modulation by Apolipoprotein E-Deficiency. (uml.edu)
  • Alzheimer's possesses complex pathologies of heterogeneous nature counting proteins as one major factor along with enzymes and mutated genes. (benthamscience.com)
  • Mutations in three genes coding for the amyloid precursor protein ( APP ), presenilin 1 ( PS-1 ), and presenilin 2 ( PS-2 ) account for most cases of early onset, autosomal dominant familial AD (FAD), but only for 2% of all the AD cases. (bmj.com)
  • Biophysical analysis of apolipoprotein E3 variants linked with development of type III hyperlipoproteinemia. (harvard.edu)
  • Our neutron reflection results demonstrate that the protein variants interact differently with the model membranes, adopting different protein conformations. (diva-portal.org)
  • Once optimized the production system, a broad characterization of two novel recombinant peptides, previously identified in human Apolipoprotein B (ApoB), was performed. (unina.it)
  • From 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) household transmission studies (enrolling April 2020 to January 2022) with rapid enrollment and specimen collection for 14 days, 61% (43/70) of primary cases had culturable virus detected ≥6 days post-onset. (cdc.gov)
  • Current evidence indicating a role of the human prion protein (PrP) in amyloid-beta (Aβ) formation or a synergistic effect between Aβ and prion pathology remains controversial. (biomedcentral.com)
  • Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures. (uchicago.edu)
  • Association of human, rat, and rabbit apolipoprotein E with beta-amyloid. (uchicago.edu)
  • Apolipoprotein E receptors mediate the effects of beta-amyloid on astrocyte cultures. (uchicago.edu)
  • Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures. (uchicago.edu)
  • SDS-stable complex formation between native apolipoprotein E3 and beta-amyloid peptides. (uchicago.edu)
  • Isoform-specific binding of apolipoprotein E to beta-amyloid. (uchicago.edu)
  • This could allow this novel bioactive substrate to be a potential treatment for atrophic AMD that would function two-fold: deliver the required monolayer of healthy RPE cells to the macula on a synthetic BM and remove diseased structures within the retina, restoring the waste/exchange pathway and preventing vision loss. (frontiersin.org)
  • Cunningham, M., Gonzalez, A. and Pollero, R.J. (2000) Characterization of Lipoproteins Isolated from the Hemolymph of the Spider Latrodectus mirabilis. (scirp.org)
  • Blom A. M . , Berggård K., Webb J. H., Villoutreix B., Lindahl G. and Dahlbäck B. (2000) Human C4b-binding protein has overlapping but not identical binding sites for C4b and streptococcal M-proteins. (lu.se)
  • Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice. (oregonstate.edu)
  • Transfer of endothelial progenitor and bone marrow cells influences atherosclerotic plaque size and composition in apolipoprotein E knockout mice. (southernbiotech.com)
  • A high-fat and high-cholesterol diet induces overt and latent oxidative damage in hippocampus of mice lacking apolipoprotein E. Open Neuro 12 , 12-18. (uml.edu)
  • Expression of WT macrophage ABCA1 in ABC1 -/- mice resulted in a small but significant increase in apoA-I levels starting 2 weeks after transplantation. (jci.org)
  • Both apolipoprotein E and immune deficiency exacerbate neointimal hyperplasia after vascular injury in mice. (uchicago.edu)
  • Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice. (uchicago.edu)
  • Effect of immune deficiency on lipoproteins and atherosclerosis in male apolipoprotein E-deficient mice. (uchicago.edu)
  • 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. (uchicago.edu)
  • Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. (antibodies-online.com)
  • A wide list of potential new antimicrobial peptides was obtained by applying this method to about 4,000 human extracellular proteins. (unina.it)
  • The high diagnostic potential of peptides and proteins from cells, tissues, and biological fluids is unquestionable. (genengnews.com)
  • The main pathological features of AD are characterised by neurofibrillary tangles and senile plaques caused by the progressive deposition of Aβ peptides in the brain, composed mainly of 39-43 peptides generated by proteolytic cleavage of the Aβ precursor protein (APP). (bmj.com)
  • Biological properties of apolipoprotein a-I mimetic peptides. (uchicago.edu)
  • Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis. (uchicago.edu)
  • Apolipoprotein C-I has a length of 57 amino acids normally found in plasma and responsible for the activation of esterified lecithin cholesterol with an important role in the exchange of esterified cholesterol between lipoproteins and in removal of cholesterol from tissues. (wikipedia.org)
  • Apolipoprotein A-I (apoAI) is a 243-residue exchangeable apolipoprotein that plays a key role in clearing the ?bad cholesterol? (pnnl.gov)
  • 2). ApoAI on preb-HDL (for specific cholesterol-binding, M.W.: ~50 kDa). (pnnl.gov)
  • It is the apoAI protein on preb-HDL that displays a unique conformation with the exposed binding sites specifically for free cholesterol. (pnnl.gov)
  • Inhibition of atherogenesis was also found in cholesterol-fed rabbits who received an infusion of apolipoprotein (apo) A-I Milano. (medscape.com)
  • [ 2 ] persons with a profound reduction of LDL cholesterol may have a decreased risk for heart disease. (medscape.com)
  • The results indicated that the addition of CaCl2 can affect the composition of HDL and LDL apolipoproteins, improving the orderliness of the HDL structure and the looseness of the LDL structure. (bvsalud.org)
  • Serum paraoxonase: effect of the apolipoprotein composition of HDL and the acute phase response. (uchicago.edu)
  • In addition, two further cryptic HDPs have been structurally and functionally characterized. (unina.it)
  • Analysis of the molecular properties of proteins extracted from organisms living under extreme conditions often highlights peculiar features. (cnr.it)
  • Mark L., Lee W. H., Villoutreix B. O., Proctor D., Blackbourn, D., Spiller B. O. and Blom A. M. (2004) KSHV complement control protein mimics human molecular mechanisms for inhibition of the complement system. (lu.se)
  • To achieve this, the neuronal SNARE (i.e., soluble N -ethylmaleimide-sensitive factor attachment protein receptor) complex brings the vesicle and presynaptic membranes in close proximity, thereby, mediating the fusion of the two membranes resulting in exocytosis of neurotransmitters. (nature.com)
  • Mounting evidence suggests that the genetic disorders/mutation and diseases change not only the protein expression patterns but also membranes themselves. (lu.se)
  • Protein deimination has, for example, been found to be involved in neo-epitope generation in autoimmunity, as well as neurodegeneration and inflammation, in epigenetic regulation via histone deimination in cancers and in the regulation of extracellular vesicle release. (westminster.ac.uk)
  • 1999. Effect of carcinogen dose fractionation, diet and source of F344 rat on the induction of colonic aberrant crypts by 2-amino-3-methylimidazo[4,5-f]quinoline. . (oregonstate.edu)
  • The QSP model included a VPA population pharma-cokinetics model that allowed the prediction of total and unbound concentrations after single and multiple oral doses considering its saturable binding to plasma proteins. (unav.edu)
  • They are found in a varying number of copies in some plasma proteins including prothrombin and urokinase-type plasminogen activator, which are serine proteases belonging to MEROPS peptidase family S1A. (embl.de)
  • Kinetic and thermodynamic characterization of dihydrotestosterone-induced conformational perturbations in androgen receptor ligand-binding domain. (harvard.edu)
  • Using 3′-UTR sequence probes, we have observed specific DNA protein binding with nuclear proteins from lymphocyte, astrocytoma, and neuroblastoma cell lines, but not from the microglia cell line. (bmj.com)
  • Quantitative peptide analysis by mass spectrometry (MS) has become indispensable for interrogation of proteins in complex biological samples. (genengnews.com)
  • Given the diversity of biological functions and biomedical applications borne by EV, there is an urgent need for efficient and reliable methods of EV characterization and isolation, to improve our understanding on EV and fully exploit their potential. (selectbiosciences.com)
  • Plasminogen, HGF/SF and HGF1/MSP represent paradigmatic examples of the modern, multi-domain proteins typically associated with vertebrate organisms and illustrate a novel evolutionary pathway that led to the emergence of molecules with growth regulatory activity from proteolytic enzymes. (embl.de)
  • High exposure to VPA can lead to carnitine depletion causing a misbalance between the intra-mitochondrial beta-oxidation and the microsomal co-oxidation, a pathway that produces toxic metabolites such as 4-en-VPA which inhibits ammonia elimination. (unav.edu)
  • 3. English A, Kosoy R, Pawlinski R, Bamezai A. A monoclonal antibody against the 66-kDa protein expressed in mouse spleen and thymus inhibits Ly-6A.2-dependent cell-cell adhesion. (southernbiotech.com)
  • Trouw L., Nilsson S., Goncalvez I., Landberg G. and Blom A. M. (2005) C4b-binding protein binds to necrotic cells and DNA, which limits DNA release and inhibits complement activation. (lu.se)
  • His team from the Center for Proteomics and Metabolomics, headed by Prof. André Deelder, developed two solid-phase peptide extraction protocols that precede an MS-based analysis. (genengnews.com)
  • In the periphery, Ly-6A/E exhibits a pattern of expression which is based on differences between the two allotypes. (southernbiotech.com)
  • 2. van Bragt MP, Ciliberti N, Stanford WL, de Rooij DG, van Pelt AM. LY6A/E (SCA-1) expression in the mouse testis. (southernbiotech.com)
  • Disturbed expression of these proteins results in synaptic dysfunction, cognitive impairment, memory loss, and neuronal degradation. (benthamscience.com)
  • The HDL formed as a consequence of the expression of WT macrophage ABCA1 migrated to the alpha position in a two-dimensional gel electrophoresis. (jci.org)
  • Alzheimer's disease (AD) is the most common cause of dementia, accounting for 60-80% of all cases [ 2 ]. (nature.com)
  • Creutzfeldt-Jakob disease (CJD) and Alzheimer's disease (AD) are protein-misfolding disorders characterized by auto-propagation and tissue deposition of protein aggregates leading to progressive neuronal dysfunction and neurodegeneration. (biomedcentral.com)
  • In my laboratory researchers are examining the roles played by axonal cytoskeletal proteins in nervous system development, and in the etiology of Alzheimer's and other related neurodegenerative diseases. (uml.edu)
  • Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer's disease patients. (nih.gov)
  • Fusion with the host cell is most likely mediated by both E1 and E2, through conformational rearrangements of the heterodimer required for fusion rather than a classical class II fusion mechanism (PubMed:16533059, PubMed:29505618, PubMed:24698129). (proteopedia.org)
  • However, familial inherited genetic cases of the disease (familial AD, FAD) represent only around 2% of total cases [ 6 ]. (nature.com)
  • Intrinsic factors of the innate immune system include the apolipoprotein B editing enzyme catalytic polypeptide-like 3 (APOBEC3) protein family. (unavarra.es)
  • Increasing vitamin K intake has been shown to increase carboxylation of extra-hepatic VKD proteins in apparently healthy adults, as well as those with osteoporosis and atherosclerosis. (vitamindwiki.com)
  • Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses. (uchicago.edu)
  • Alters lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage (PubMed:14602201). (proteopedia.org)
  • Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer. (oregonstate.edu)
  • Interestingly, the spectra of the fully oxidized species, obtained by treating the protein with ferricyanide, show the simultaneous presence of peaks corresponding to different hexacoordinated states, the aquomet and the hemichrome. (cnr.it)
  • Recent advancement in technology enabled to cultivate those useful species in quantity, and quality-controlled distribution in the conventional granule forms has begun since 1970's, and currently Huaier is recognized widely as the patent anti-cancer drug in China (Chinese administration license No. Z-20000109) [2, 4, 5]. (fortunejournals.com)
  • Characterization of Cerebrospinal Fluid BACE1 Species. (nih.gov)
  • Towards Predicting Protein-Protein Interactions in Novel Organisms. (uml.edu)
  • Blom, A. M. , Rytkönen, A., Vasquez, P., Dahlbäck, B. and Johnsson, A-B. (2001) A novel interaction between type IV pili of Neisseria gonorrhoeae and complement regulatory protein - C4b-binding protein. (lu.se)
  • Regulation of apolipoprotein E biosynthesis by cAMP and phorbol ester in rat ovarian granulosa cells. (uchicago.edu)
  • Sjöberg A., Trouw L., McGrath F., Hack E. C. and Blom A. M. (2006) Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein. (lu.se)
  • When proteins rich in triglycerides like chylomicrons and VLDL are broken down, this apoprotein is transferred again to HDL. (wikipedia.org)
  • In order to identify by a rational approach further human proteins carrying cryptic HDPs, we recently developed an in-silico screening method to localize antimicrobial regions hidden inside the primary structure of precursor proteins. (unina.it)
  • On diagnostic grounds of AD C-reactive protein, pentraxins, collapsin response mediator protein-2, and growth-associated protein-43 represent the future of new possible biomarkers for diagnosing AD. (benthamscience.com)
  • It is one of the most positively charged proteins in the human body. (wikipedia.org)
  • One of the duplicates encodes a basic protein designated apoC-IB that is orthologous to human apolipoprotein C-I. The other encodes an acidic protein, apoC-IA, that is orthologous to the virtual protein encoded by the pseudogene. (wikipedia.org)
  • Many human proteins with functions not necessarily related to host defense behave as sources of HDPs. (unina.it)
  • One of these HDPs has been identified in human 11-hydroxysteroid dehydrogenase-1 β-like, the other represents the first HDP from an archaeal protein, the transcription factor Stf76 encoded by the hybrid plasmid-virus pSSVx from Sulfolobus islandicus. (unina.it)
  • Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a). (uchicago.edu)
  • Here, we reviewed the physiological/pathological roles and therapeutic significance of nearly all the proteins associated with AD that addresses putative as well as probable targets for developing effective anti-AD therapies. (benthamscience.com)
  • By using the NanoAnalyzer, single-particle characterization can be achieved which simultaneously measures the side scatter (40 -1000nm) and fluorescent properties of particles. (selectbiosciences.com)
  • Through electrophoresis it was observed that Gr-VHDL has three proteins: a predominant band of 68 kDa and two others of 99 and 121 kDa. (scirp.org)
  • 2001. Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo. . (oregonstate.edu)
  • Webb, J. H., Villoutreix, B. O., Dahlbäck, B. and Blom A. M. (2001) Localization of a hydrophobic binding site for protein S on the b-chain of C4BP. (lu.se)