• In humans, gamma-glutamyl hydrolase is encoded by the GGH gene. (wikipedia.org)
  • A human and mouse gene that showed high amino acid identity to the rat ninjurin protein, were cloned and mapped. (ucl.ac.uk)
  • A human gene showing high amino acid homology to the lymphoid cell activation antigen CD39 was cloned and mapped to 9q34(CD39L1). (ucl.ac.uk)
  • Database searches with the CD39L1 protein sequence revealed that it is likely to be a member of the ectoATPase gene family, and that several other human homologues exist. (ucl.ac.uk)
  • The underlying genetic defect in patients with NBCCS was recently shown to be due to mutations in the human homologue of the drosophila segment polarity gene patched. (ucl.ac.uk)
  • The hOAT3 protein was shown to be localized in the basolateral membrane of renal proximal tubules and the hOAT3 gene was determined to be located on the human chromosome 11q12-q13.3 by fluorescent in situ hybridization analysis. (aspetjournals.org)
  • The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. (musc.edu)
  • AceView: gene:him-8, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView. (nih.gov)
  • Subsequently, the AdnaTest ProstateCancerPanel AR-V7 is used for molecular characterization by analyzing gene expression of AR-V7 and further prostate cancer associated genes. (qiagen.com)
  • Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease. (scielo.br)
  • Characterization of the Wilson disease gene encoding a P-type copper transposting ATPase: genomic organization, alternative splicing, and structure/function predictions. (scielo.br)
  • 1990). Characterization and Expression of the Gene for the Human Fc Receptor γ Subunit. (igem.org)
  • The work described in this thesis focussed on the cloning of the GPI8 gene from Leishmania mexicana and its characterisation. (gla.ac.uk)
  • All human infections caused by a new influenza subtype are required to be reported under the International Health Regulations (IHR, 2005).4 This includes any influenza A virus that has demonstrated the capacity to infect a human and its haemagglutinin gene (or protein) is not a mutated form of those, i.e. (who.int)
  • These monocytes isolation protocols can contribute to the development of reliable methods for the purification of human dendritic cells for research and clinical applications. (jove.com)
  • Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar. (harvard.edu)
  • Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
  • 2009). Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins. (igem.org)
  • Human mesenchymal stem cells (HMSCs) are multipotent somatic stem cells that can be isolated from a variety of tissues such as the bone marrow, adipose tissue, and dental pulp. (frontiersin.org)
  • This study compares two different methods of human monocyte isolation for obtaining in vitro dendritic cells (DCs). (jove.com)
  • The overall goal of this study is to compare two different methods of human monocyte isolation for dendritic cell generation in vitro and to characterize the CT11c, CT14 cell surface expression of the resulting monocyte derived populations by imaging flow cytometry. (jove.com)
  • During the past year, we have made the following significant findingsobservations i employing a specific feeder layer rSVM, human prostate cancer xenograft cells from 3D structures we have termed glandoids, ii glandoids appear to be clonal and form tumors in vivo that recapitulate the parent xenograft and iii readily obtaining rSVM for in vitro cultures is challenging. (dtic.mil)
  • a partial map of receptors on human mast cells cultured in vitro. (bdbiosciences.com)
  • 2009). Physiologic Oxygen Concentration Enhances the Stem-Like Properties of CD133+ Human Glioblastoma Cells In Vitro. (igem.org)
  • AdnaTest ProstateCancerPanel AR-V7 allows molecular characterization of CTCs using the Combination of Combinations Principle (COCP). (qiagen.com)
  • Molecular cloning and characterization of a human uronyl 2-sulfotransferase that sulfates iduronyl and glucuronyl residues in dermatan/chondroitin sulfate. (harvard.edu)
  • In addition to the microvesicles released during the treatment of human erythrocytes with Ca2+ and ionophore A23187, a new subpopulation of still smaller dense vesicles ('nanovesicles') has now been identified. (uea.ac.uk)
  • Mycoplasma genitalium is a human pathogen adhering to host target epithelial cells and causing urethritis, cervicitis and pelvic inflammatory disease. (nature.com)
  • Studies on protein-polysaccharide complex (proteoglycan) from human nucleus pulposus. (wikidata.org)
  • The predicted protein shares 31% identity with yeast and human homologues. (gla.ac.uk)
  • A cDNA encoding a multispecific organic anion transporter 3 (hOAT3) was isolated from a human kidney cDNA library. (aspetjournals.org)
  • Reverse transcription results in cDNA, which is subsequently used as template for preamplification and tumor cell detection and characterization by qRT-PCR. (qiagen.com)
  • Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells. (bdbiosciences.com)
  • Iduronic acid-rich proteoglycans (PGIdoA) and human post-burn scar maturation: isolation and characterization. (harvard.edu)
  • The aim of this thesis was to isolate transcribed sequences from the Nevoid Basal Cell Carcinoma Syndrome (NBCCS) candidate region on human chromosome 9q22. (ucl.ac.uk)
  • Since 1986, two human tickborne diseases caused by Ehrlichia spp. (cdc.gov)
  • Ehrlichia chaffeensis causes a tick-borne disease affecting both animals and humans. (kenyon.edu)
  • The first incident of human ehrlichiosis (the infection caused by the Ehrlichia bacterium) was reported in Japan in 1954. (kenyon.edu)
  • Among the OAT isoforms, rOAT3, as well as rOAT1, exhibits a markedly wide substrate selectivity, and its human homolog is considered a key molecule in the renal handling of organic anions. (aspetjournals.org)
  • Our study shows that Jurkat human T cells have a molecule that reacts with both anti-CR2 antibodies and the third component of complement, C3. (nih.gov)
  • Additionally, we are performing biochemical characterization of this molecule to determine how it may affect cell adhesion and other cell functions. (cincinnatichildrens.org)
  • Morphological and proliferative analyses, as well as immunophenotype characterization with monoclonal antibodies against CD117, CD34 and CD45 surface receptors were performed. (bvsalud.org)
  • Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. (bdbiosciences.com)
  • A comparative analysis of single-cell RNA sequencing data collected from three HUCMSCs and two human umbilical vein endothelial cell (HUVEC) controls identified eight common cell clusters, all of which indicated regenerative potential specific for HUCMSCs. (nature.com)
  • Here, we describe the isolation, characterization, and expansion of human saphenous vein endothelial cells (hSVECs). (bvsalud.org)
  • The main advantage of these protocols is that they facilitate the isolation of human monocytes and their differentiation into viable and functional monocyte derived cells. (jove.com)
  • Nurmi T, Mursu J, Heinonen M, Nurmi A, Hiltunen R, Voutilainen S (2009) Metabolism of berry anthocyanins to phenolic acids in humans. (springer.com)
  • A recent study on children reported that the common clinical signs and symptoms of patients with human monocytotrophic ehrlichiosis (HME) include headache, rash, myalgia, nausea/vomiting, fever and altered mental status. (kenyon.edu)
  • Inseparable iduronic acid-containing proteoglycan PG(IdoA) preparations of human skin and post-burn scar tissues: evidence for elevated levels of PG(IdoA)-I in hypertrophic scar by N-terminal sequencing. (harvard.edu)
  • 2004). Fcγ receptor signaling in primary human microglia: differential roles of PI-3K and Ras/ERK MAPK pathways in phagocytosis and chemokine induction. (igem.org)
  • In an effort to identify and characterize minor forms of human liver cytochrome P450, immunoblot analyses of microsome samples were developed with antibodies to various P450s that recognized multiple human P450s. (nih.gov)
  • The feasibility of using human autoimmune antibodies to isolate and characterize specific nuclear ribonucleoprotein (nRNP) complexes was investigated. (eurekamag.com)
  • An event of human ehrlichiosis was not reported in the United States until 1986. (kenyon.edu)
  • 1986. Environmentally significant volatile organic pollutants in human blood. (cdc.gov)
  • E. chaffeensis has been isolated in white-tailed deer and even dogs, with the latter being a possible carrier of the tick which can infect humans with HME. (kenyon.edu)
  • Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. (mdpi.com)
  • Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? (mdpi.com)
  • Update: universal precautions for prevention of transmission of human immunodeficiency virus, hepatitis B virus, and other bloodborne pathogens in healthcare settings. (bdbiosciences.com)
  • Telomeres shorten during ageing of human fibroblasts. (cshlpress.com)
  • AdnaTest ProstateCancerPanel AR-V7 contains Oligo (dT)25 Beads for the isolation of mRNA from the lysate of pre-enriched tumor cells. (qiagen.com)
  • This method can also be applied as an alternative for the isolation of other rare cells at an adequate yield for downstream research applications. (jove.com)
  • This study was developed to compare the morphological, proliferative and immunophenotypic profiles of pulp cells from permanent and primary teeth, obtained by two isolation methods. (bvsalud.org)
  • F-10 Ham supports the growth of human diploid cells, white blood cells for chromosomal analysis, and primary explants of rat, rabbit, and chicken tissues. (sigmaaldrich.com)
  • Processing-dependent and -independent pathways for recognition of iodinated contrast media by specific human T cells. (thieme-connect.com)
  • Isolation and characterization of human tonsil dendritic cells. (bdbiosciences.com)
  • Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. (bdbiosciences.com)
  • The human pathogen Mycoplasma genitalium , a member of the pneumoniae cluster of mycoplasmas, binds to eukaryotic cells by means of its adhesion complex, the Nap. (nature.com)
  • 2009). Isolation and characterization of cancer stem like cells in human glioblastoma cell lines. (igem.org)
  • 2005). Notch1 and syndecan-1 potent human embryonic stem (ES) cells. (lu.se)
  • 2002). In humans, SSEA4 is expressed by building the nervous system but also for their prospec- nonneural cells such as the erythrocytes (Kannagi et al. (lu.se)
  • Finally, we would like to emphasize the necessity of associating new plant breeding and genetic studies of berries with the expression and overexpression of compounds for human health and healthy aging. (springer.com)
  • Four P450s were recognized in immunoblot analyses of human liver microsome samples developed with an antibody previously demonstrated to specifically recognize rat 2B1/2. (nih.gov)
  • The relative levels of 2C19 were determined in 14 human liver microsome samples by quantitative immunoblot analyses developed with the anti-2C9/10 antibody. (nih.gov)
  • The levels of 2C19 were compared to the relative levels and catalytic activities of multiple human liver P450s. (nih.gov)
  • Immunohisto- have been used for positive selection of NSCs from em- chemistry on human embryonic central nervous system bryonic mice (Nagato et al. (lu.se)
  • There are two common types of influenza viruses that cause human infection - influenza A and influenza B. Influenza A viruses caused several influenza pandemics in the 20th century, and a pandemic caused by the influenza A(H1N1)pdm09 virus occurred in 2009. (who.int)
  • The overall public health risk from currently known influenza viruses at the human-animal interface has not changed, and the likelihood of sustained human-to-human transmission of these viruses remains low. (who.int)
  • Here we report application of human umbilical cord mesenchymal stem cell (HUCMSC)-derived therapy for pulmonary arterial hypertension (PAH). (nature.com)
  • have been recognized in the United States: human monocytic ehrlichiosis (HME), caused by E. chaffeensis, and human granulocytic ehrlichiosis (HGE), caused by an agent closely related to E. equi (1,2). (cdc.gov)
  • In 1991, E. chaffeensis was isolated from a military recruit stationed at Fort Chaffee, Arkansas, this was the first isolation from a human in the US. (kenyon.edu)
  • 3 Dawson) Public attention peaked after this bacterium was found to be the causative agent of human monocytotropic ehrlichiosis (HME). (kenyon.edu)
  • In the presence of active S. equina infection, antigens from the adult and microfilaraemic stages showed the highest degree of cross-reaction with human sera. (who.int)
  • 2 Between 2003 and 2012, 123 human cases of A(H5N1) infection were confirmed from 40 of the 63 provinces in Viet Nam, with 81 cases (66%) from northern Viet Nam. (who.int)
  • A(H1N2) variant viruses and one human case of infection with an influenza A(H3N2) variant virus were reported officially.3 One additional human case of infection with an influenza A(H1N1)v virus was detected. (who.int)
  • Since the last risk assessment on 21 May 2021, one new laboratory-confirmed human case of influenza A(H5N6) virus infection was reported from China to WHO on 30 May 2021. (who.int)
  • 1. What is the likelihood that additional human cases of infection with avian influenza A(H5) viruses will occur? (who.int)
  • Good quality serological investigations may be useful in differentiating infection from contamination in these cases and allow for better assessment of the risk of human infection. (who.int)
  • Human chorionic gonadotropin (hCG) is a dimer consisting of a 145 amino acid beta-subunit that is unique to hCG and a 92 amino acid alpha-subunit. (medscape.com)
  • 1991. Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans. (cdc.gov)
  • However, because reagents for these assays came from human volunteers, the reagents were available only in limited quantities and only at certain facilities. (cdc.gov)
  • According to the Center for Disease Control and Prevention (CDC), HME is one of the most frequent life-threatening tick-borne zoonoses (a disease that can be transmitted from an animal to a human) but frequently goes unreported in the United States since symptoms are similar to many other diseases or infections a person may get from insect bites, like Lyme disease from a tick. (kenyon.edu)
  • Members of this species vary from very pathogenic agents causing different types of diseases including meningitis, gastroenteritis, and septicemia, just to cite a few, to harmless organisms living in the intestines of both humans and animals. (intechopen.com)
  • As a scientist she has been involved in mapping the human genome and identifying genes and mutations, which give rise to heritable disorders. (bepress.com)
  • Therefore, the culture of human adipocytes provides a model system for the study of adipocyte derived EVs. (ox.ac.uk)
  • Here, we provide a detailed protocol for the extraction of total small EVs from cell culture media of human gluteal and abdominal adipocytes using filtration and ultracentrifugation. (ox.ac.uk)
  • In the 2014-2015 winter season, H5N1 was circulating heavily in poultry flocks and caused an unprecedented number of human infections. (who.int)
  • Human infections with viruses of animal origin are expected at the human-animal interface wherever these viruses circulate in animals. (who.int)
  • Even though small clusters of A(H5) virus infections have been reported previously including those involving healthcare workers, current epidemiological and virological evidence suggests that influenza A(H5) viruses have not acquired the ability of sustained transmission among humans, thus the likelihood is low. (who.int)
  • The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • Most human cases were exposed to A(H5) viruses through contact with infected poultry or contaminated environments, including live poultry markets. (who.int)
  • Since the viruses continue to be detected in animals and environments, further human cases can be expected. (who.int)
  • 2. What is the likelihood of human-to-human transmission of avian influenza A(H5) viruses? (who.int)
  • Sequence comparison of L. mexicana, yeast and human GPI8 proteins identified two potential active site cysteine residues. (gla.ac.uk)
  • In view of this, the human studies investigating the bioavailability and potential toxicity of phenolics are receiving more attention. (springer.com)
  • Valent P, Besemer J, Muhm M, Majdic O, Lechner K, Bettelheim P. Interleukin 3 activates human blood basophils via high-affinity binding sites. (bdbiosciences.com)
  • The development of the human blood-CSF-brain barrier. (cdc.gov)