• Chemokine (C-C motif) ligand 24 (CCL24) also known as myeloid progenitor inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (eotaxin-2) is a protein that in humans is encoded by the CCL24 gene. (wikipedia.org)
  • The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MGSA-α). (wikidoc.org)
  • CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. (wikipedia.org)
  • PF4 is chemotactic for neutrophils , fibroblasts and monocytes , and interacts with a splice variant of the chemokine receptor CXCR3 , known as CXCR3B. (wikidoc.org)
  • However, potential associations between chemokine and chemokine receptor polymorphisms and BD have been fundamentally understudied. (psychiatryinvestigation.org)
  • To identify participation of chemokines in BD pathogenesis, we examined genetic variants of several chemokine and chemokine receptor genes. (psychiatryinvestigation.org)
  • Our findings indicate an association between genetic variants of certain chemokine and chemokine receptor (especially MCP-1) genes and BD. (psychiatryinvestigation.org)
  • 1 By contrast, potential associations between chemokine and chemokine receptor polymorphisms and BD have been fundamen tally understudied and only MCP-1 gene polymorphisms have been investigated in patients with BD. (psychiatryinvestigation.org)
  • This chemokine is also strongly chemotactic for resting T lymphocytes and slightly chemotactic for neutrophils. (wikipedia.org)
  • Assessment of blister fluid-derived chemokines showed a persistent presence of several chemotactic molecules, including CXCL1 + 2 and CXCL5. (biomedcentral.com)
  • The key mechanism that regulates recruitment of leukocytes and progenitor stem cells to distal anatomical tissues affected with disease is chemotaxis, which depends on the signaling molecules, chemokines, and acts primarily as part of the host defense and repair mechanism. (biomedcentral.com)
  • Despite their well-known involvement in neuroimmunologic processes, the pathogenic significance of chemokines, which are small signaling proteins with the ability to induce chemotaxis, has been relatively understudied in BD as compared with other immune system components. (psychiatryinvestigation.org)
  • The effect of Mast cell Tryptase to the Expression of Eotaxin-1/CCL11, Eotaxin-2/CCL24 and Eotaxin-3/CCL26 by Conjunctival Fibroblasts. (nii.ac.jp)
  • CCL24 is a small cytokine belonging to the CC chemokine family. (wikipedia.org)
  • [8] The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. (wikidoc.org)
  • Z200369CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. (topsan.org)
  • Comprehensive proteomic screening of chemokines in the blister fluids of DEB-affected mice was conducted to define the inflammatory and immune activities, thus providing potential to examine local biological mechanisms and define the protein signature within lesional skin as a potential marker of disease activity. (biomedcentral.com)
  • Z200049Exodus-2 has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. (topsan.org)
  • [3] Its gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22 . (wikidoc.org)
  • CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin -like stalk and a chemokine domain on top. (wikidoc.org)
  • CCL24 is a small cytokine belonging to the CC chemokine family. (wikipedia.org)