Characteristics cells. Medical search. Frequent questions

Histologically, ALCL is characterized by sheets of large pleomorphic cells with abundant cytoplasm, horseshoe- or wreath-shaped nuclei, and multiple prominent nucleoli. (medscape.com)
Two morphological types of cell death were found: apoptosis which was characterized by round or semilunar nuclear chromatin condensations, condensation and shrinkage of the cytoplasm and formation of apoptotic bodies, and cell death without the morphological features of apoptosis which was characterized by pyknotic nuclear chromatin condensations, vacuolated cytoplasm and the formation of numerous intercellular spaces. (karger.com)
The cytoplasm of fungal cells contain different organelles such as Endoplasmic reticulum, mitochondria, ribosome , Golgi bodies etc.and inclusions such as stored foods, pigments and secretory granules. (microbiologynote.com)
At the hyphal tip, the cytoplasm contains Golgi vesicles known as the chitosomes which filled with cell wall materials. (microbiologynote.com)
Plant cells contain a substance called cytoplasm. (mindmeister.com)
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment. (jove.com)
In I-cell disease, the characteristic finding is abnormal vacuolization or inclusions that appear in the cytoplasm. (medscape.com)

ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
E1a thus appeared to partially convert diverse human tumor cells into an epithelial phenotype. (rupress.org)
Multiplexed immunohistochemistry demonstrated the predominance of CD8 + effector and central memory T cells (T CM ) in close proximity to tumor cells in patients with a favorable therapy response. (merkelcell.org)

Aim: The aim of the study was to evaluate the clinicopathological and prognostic significance of morphological subtyping of papillary renal cell carcinoma (PRCC). (elsevierpure.com)
Methods: The patients treated for renal cell carcinoma in our department from January 1985 to March 2006 were evaluated retrospectively. (elsevierpure.com)
To determine the prognostic factors, we re-evaluated the pathological stage according to the 2002 TNM classification of malignant tumors, and the tumor type of renal cell carcinoma according to the 2004 World Health Organization histological classification. (elsevierpure.com)
Purpose: To analyze the clinical characteristics of renal cell carcinoma (RCC) in Korean patients with von Hippel-Lindau (VHL) disease. (elsevierpure.com)
The present studies examined the response of renal epithelial cells to oxalate, a metabolite excreted by the kidney that produces oxidant stress and death of renal cells at pathophysiological concentrations. (elsevierpure.com)
These studies employed LLC-PK1 cells, a renal epithelial cell line from pig kidney and NRK-52E (NRK) cells, a line from normal rat kidney, and compared the effects of oxalate with those of known apoptotic agents. (elsevierpure.com)
These studies indicated that oxalate-induced death of renal epithelial cells exhibits several features characteristic of apoptotic cell death, including increased production of ceramide, increased abundance of apoptotic bodies, and marked sensitivity to the level of expression of the antiapoptotic gene bel-2. (elsevierpure.com)
These results suggest that toxic concentrations of oxalate trigger both forms of cell death in renal epithelial cells. (elsevierpure.com)
Other sites of abnormal cell vacuolization include the renal glomerular podocytes and in the fibroblasts of the liver's periportal spaces. (medscape.com)

Our preceding studies demonstrated that cysteine414 (zinc-binding site of mCRY1) - alanine mutant mCRY1 transgenic mice (TG mice) exhibit diabetes characterized by the reduction of β-cell proliferation caused by senescence-associated secretory phenotype (SASP)-like characters of β-cells. (diabetesjournals.org)
When genetically susceptible individuals are exposed to infection, stress or trauma, cutaneous dendritic cells are activated to produce tumor necrosis factor (TNF)-α and interleukin (IL)-23, which subsequently stimulate the proliferation and differentiation of proinflammatory T cells. (nature.com)
Matrix stiffness as an important physical attribute of extracellular matrix exerts significant impacts on biological behaviors of cancer cells such as growth, proliferation, motility, metabolism and invasion. (oncotarget.com)
1994. Mesothelial cell proliferation: A nonspecific response to lung injury associated with fibrosis. (cdc.gov)

To this end, the biophysical characteristics that describe the osmotic reaction of CD34 + CD38 - human fetal liver stem cell candidates were studied using fluorescent microscopy. (ulster.ac.uk)

Characteristic vibrational bands were analyzed with respect to storage time-dependent changes in peak position and in intensity. (ru.nl)

Animal and human studies have demonstrated that stem cells isolated from placentas and umbilical cords may differentiate into a variety of specialized tissue, such as nerve, liver, heart, kidney, bone marrow, and cartilage cells, among many other types. (cellmedicine.com)
The precise origin of adult stem cells in mature tissues is unknown, although bone marrow is suspected. (cellmedicine.com)
Indeed, recent studies have found that even liver regeneration comes from bone marrow, which produces new (adult) stem cells capable of "homing in" on the liver. (cellmedicine.com)
Adult stem cells capable of forming blood, and derived from bone marrow, have been used in transplants for over 30 years. (cellmedicine.com)
The first studies to be conducted on adult stem cells occurred in the 1960s, with bone marrow. (cellmedicine.com)
In the 1980's, Arnold Caplan and his colleagues published an isolation method of fibroblast-like stromal cells from bone marrow and first identified them as mesenchymal stem cells (MSCs) because of their multilineage differentiation potential ( Caplan, 1991 ). (frontiersin.org)
Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, splenomegaly, and anemia with nucleated and teardrop-shaped red blood cells. (msdmanuals.com)
Overview of Myeloproliferative Neoplasms Myeloproliferative neoplasms are clonal proliferations of bone marrow stem cells, which can manifest as an increased number of platelets, red blood cells (RBCs), or white blood cells (WBCs). (msdmanuals.com)
Primary myelofibrosis results from neoplastic transformation of a multipotent bone marrow stem cell. (msdmanuals.com)
These primary myelofibrosis progeny cells stimulate bone marrow fibroblasts (which are not part of the neoplastic transformation) to secrete excessive collagen. (msdmanuals.com)

This study compared demographic, product use, and clinical characteristics of EVALI patients in Illinois who reported using only nicotine-containing e-cigarette, or vaping, products with those of patients who reported using any THC-containing products. (cdc.gov)
Materials and Methods: The clinical characteristics of 21 patients who were diagnosed with VHL disease were analyzed. (elsevierpure.com)
In patients with RCC related to VHL disease, the clinical characteristics of the tumor, type of pathology and survival were investigated. (elsevierpure.com)
Spranger and Wiedermann subsequently classified this disease as mucolipidosis type II (ML II) because it had clinical characteristics that included mucopolysaccharidoses and sphingolipidoses. (medscape.com)

Many other cell types emerge via epithelial-mesenchymal differentiation. (rupress.org)
Taken together, our results suggest that the direct trans-differentiation of endocrine cells (possibly β cells) to ductal cells is involved in the generation of the intra-islet ductal cells. (diabetesjournals.org)
Scholars@Duke publication: Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts. (duke.edu)
To investigate the characteristics of exosomes derived from dental pulp stem cells (DPSCs) in the direction of odontogenic differentiation, to analyze the differences in microRNA expression profile between exosomes derived from undifferentiated and odontogenic DPSCs, and to analyze their possible signal transduction pathways . (bvsalud.org)
Odontogenic differentiation group showed a large number of dark deposits in alizarin red staining and the cells were darkly stained in alkaline phosphatase staining , while the cells in normal culture medium group did not show obvious dyeing. (bvsalud.org)

Last, we show that established UM cell lines and UM STCs are plastic in nature and switch their phenotype in response to environmental stimuli. (whiterose.ac.uk)

0.5% of repertoire) post-treatment than non-responding patients or controls, and this correlates with effector memory T cell percentage. (ox.ac.uk)
Single-cell RNA-sequencing of eight post-treatment samples demonstrates that large clones overexpress genes implicated in cytotoxicity and characteristic of effector memory T cells, including CCL4, GNLY and NKG7. (ox.ac.uk)

Beyond the 8th week of development, the embryo has matured into a fetus and the embryonic stem cells have matured into fetal stem cells, which exist until birth (after which time they are known as "adult" stem cells). (cellmedicine.com)
Embryonic and fetal stem cells are known to be pluripotent, which makes them attractive candidates for use in medical therapies. (cellmedicine.com)
Although it was originally thought that only embryonic and fetal stem cells exhibit pluripotency and are free of antigens or HLA, it is now known that placental and umbilical cord stem cells also exhibit these same desirable characteristics. (cellmedicine.com)

Many previous reports have indicated that microRNA and EMT regulated cancer stem cell characteristics, and miR-17 and MKL-1 were involved as a critical gene in migration and invasion in the EMT pathway. (nih.gov)

Title : Comparison response patterns on landline and cell phone in a call back survey: effects of demographic characteristics and lag days Personal Author(s) : Qin, Xiaoting;Bailey, Cathy M.;Zahran, Hatice S. (cdc.gov)

Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
Each of the cell lines also reacted with antibodies against neural cell adhesion molecules, but none of them were positive for antibodies against glial fibrillary acidic protein, keratin, microtubule-associated protein tau and microtubule-associated protein 2, human lymphocyte antigen-DR, epidermal growth factor receptor, and T-cell antigen. (duke.edu)
Anti-human lymphocyte antigen-A,B and anti-beta 2-microglobulin antibodies reacted with xenografts of D384 Med and D425 Med and were weakly positive for a small population of D384 Med cultured cells. (duke.edu)

2 Psoriasis is a disease with innate and adaptive immune system disorder and dendritic cells, neutrophils, keratinocytes and T cells play major roles in the pathogenesis. (nature.com)

E1a induces the expression of epithelial characteristics. (rupress.org)
Differences in the biological effects of crocidolite asbestos and two glass fibres on epithelial lung cells. (cdc.gov)

Mesenchymal stem cells (MSCs) have immunomodulatory properties. (nature.com)
Although mesenchymal stem cells (MSCs) have been shown as a novel approach in tissue regeneration, the therapeutic potential of MSCs mediated by the interaction between MSC-derived paracrine mediators and Mφs remains elusive. (frontiersin.org)
These are observed in cells of mesenchymal origin, especially fibroblasts. (medscape.com)

BACKGROUND: To maintain a high quality of red blood cells (RBCs), RBC characteristics must be followed during storage under blood bank conditions. (ru.nl)

Through RT-PCR, Western Blot, flow cytometry, immunofluorescence, sphere formation xenograft tumor assays and drug resistance, the role of miR-17-5p and MKL-1 on promoting stem cell-like properties of gastric cancer were verified in vivo and vitro . (nih.gov)
The fluorochrome-labeled cells are analyzed by flow cytometry, which categorizes individual cells according to size, granularity, fluorochrome, and fluorochrome intensity. (cdc.gov)

A single assay for multiple storage-sensitive red blood cell characteristics by means of infrared spectroscopy. (ru.nl)
Oxalate-induced cell death also exhibits several characteristics of necrotic cell death in that the majority of the cells exhibited cellular and nuclear swelling after oxalate treatment and showed little evidence of DNA cleavage by TUNEL assay. (elsevierpure.com)

Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma. (ox.ac.uk)

Placental stem cells are isolated from placentas, and umbilical cord stem cells are isolated from umbilical cords, at the time of a healthy birth. (cellmedicine.com)
Unlike with embryonic stem cells, the destruction of an embryo is not involved in the gathering of placental and umbilical cord stem cells, yet the placental and umbilical cord stem cells exhibit the same pluripotency as do embryonic stem cells. (cellmedicine.com)
Furthermore, placental and umbilical cord stem cells are free of antigens, HLA or other cellular markers that could potentially be rejected by the body. (cellmedicine.com)
Additionally, umbilical cord stem cells were used in the successful treatment of a woman who had been paralysed for 19 years. (cellmedicine.com)

Cytoadherence characteristics of Plasmodium falciparum isolates in Thailand using an in vitro human lung endothelial cells model. (ajtmh.org)
Using an in vitro model of human lung endothelial cells, we studied different characteristics of Plasmodium falciparum isolates as potential factors for malaria severity in 2 Thai patient groups: 27 with complicated malaria and 42 with uncomplicated malaria. (ajtmh.org)

The dependence of the weight of the electron-donating material, poly(3-hexylthiophene-2,5-diyl) (P3HT), and electron-accepting material, [6,6]-phenyl C 61 butyric acid methyl ester (PCBM), on the photovoltaic characteristics of a polymer photovoltaic (PV) cell was investigated. (springer.com)
Cell death in the axial structures, i.e. spinal cord, notochord and surrounding mesenchyme and somites, was analyzed using light and electron microscopy. (karger.com)
A light and electron microscopic study of naturally occurring and induced cell loss during development. (karger.com)
Electron microscopy illustrated characteristics of native RPE. (arvojournals.org)
Ultrastructural characteristics of oligodendrocyte precursor cells in the early postnatal mouse optic nerve observed by serial block-face scanning electron microscopy. (mendeley.com)
Here atom probe tomography, transmission electron microscopy and electron beam-induced current are used to clarify the dependence of Se content on the photoactive properties of CdTe x Se 1₋x alloy layers in bandgap-graded CdTe solar cells. (osti.gov)

Cells Tissues Organs (2001) 169 (4): 347-354. (karger.com)
It was found that absence of immunosuppression, a limited number of tumor-affected organs, and an elevated number of 'killer' (CD8 T) cells within the tumor were associated with a higher chance of responding to immune therapy. (merkelcell.org)
Other signs and symptoms that may occur in Langerhans cell histiocytosis, depending on which organs and tissues have Langerhans cell deposits, include swollen lymph nodes, abdominal pain, yellowing of the skin and whites of the eyes (jaundice), delayed puberty, protruding eyes, dizziness, irritability, and seizures. (medlineplus.gov)
In primary myelofibrosis, nucleated red blood cells (normoblasts) and myelocytes are released into the circulation (leukoerythroblastosis) when there is extramedullary hematopoiesis (ie, non-marrow organs have taken over blood cell production because of the fibrosed marrow). (msdmanuals.com)

They found similarities across certain families of immune cells, such as macrophages, as well as differences in others. (sanger.ac.uk)
By using single-cell sequencing data we have been able to reveal around a hundred different kinds of immune cells including macrophages, B cells, and T cells, uncovering crucial information about how the immune system works. (sanger.ac.uk)
1998. Activation of alveolar macrophages and peripheral red blood cells in rats exposed to fibers/particles. (cdc.gov)

These papers are two of four major studies published in Science this week, which have created comprehensive and openly available cross-tissue cell atlases. (sanger.ac.uk)
Using CellTypist and further in-depth analysis, the researchers created a cross-tissue immune cell atlas that revealed the relationship between immune cells in one tissue and their counterparts in others. (sanger.ac.uk)
For example, some memory T cells show unique features depending on which tissue they are in. (sanger.ac.uk)
The nature of the response has important consequences for the injured tissue in that necrotic cells elicit inflammatory responses, whereas apoptotic cells do not. (elsevierpure.com)
however, significant vacuolization is present in the heart's connective tissue cells of the heart valves. (medscape.com)

Previously underexplored immune cell populations have been mapped across multiple tissues in development and adulthood to provide new insights into how our immune system works. (sanger.ac.uk)
One study focuses on the early development of the immune system and the localisation of immune cells across several tissues. (sanger.ac.uk)
The other study looks at immune cells in multiple tissues from adult individuals, providing a framework for prediction of cell type identity and insights into immunological memory. (sanger.ac.uk)
Published today (12 May 2022) in Science , both studies explore the similarities and differences of immune cells across different tissues, which are understudied, compared to those circulating in the blood. (sanger.ac.uk)
Knowing more about immune cell traits and reactions in these tissues at different stages of life could help future research into therapies that aim to produce or enhance an immune response to fight disease, such as vaccinations or anti-cancer treatments. (sanger.ac.uk)
They used spatial transcriptomics and single-cell RNA sequencing to map the exact location of specific cells within developing tissues. (sanger.ac.uk)
This comprehensive atlas of human immune development reveals tissues involved in the formation of blood and immune cells, enhancing our understanding of immune and blood disorders. (sanger.ac.uk)
In the second study **, scientists from the Wellcome Sanger Institute, the University of Cambridge, and their collaborators simultaneously analysed immune cells across 16 tissues from 12 individual adult organ donors. (sanger.ac.uk)
We have created a catalogue of immune cells within the adult human body, allowing us to automatically identify cell types across multiple tissues. (sanger.ac.uk)
The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)

In most cases, dying cells during development exhibit generalized morphological features typical of apoptosis. (karger.com)
According to our findings, apoptosis seems to be the most frequently observed type of PCD, but it is not the exclusive type of morphological cell death during the development of axial structures in human embryos. (karger.com)

Sixty percent of cases express 1 or more T-cell antigens (CD3 + , CD43, or CD45RO). (medscape.com)
The aim is to produce an attenuated virus that incorporates the key immunizing antigens and antigenic determinants of circulating wild influenzaviruses but retains the stable genetic and phenotypic characteristics of the attenuated donor strain when given to susceptible individuals on a wide scale. (who.int)

Confluent monolayers of adult human RPE cultures exhibit characteristics of native RPE. (arvojournals.org)

However, the effect of microRNA miR-17/MKL-1 on gastric cancer stem cells has not been studied yet. (nih.gov)
Characteristics and microRNA expression profile of exosomes derived from odontogenic dental pulp stem cells]. (bvsalud.org)

Spectra of the soluble cell components were acquired separately after hypotonic lysis of the cells, followed by centrifugation. (ru.nl)
The results obtained suggest that post-hypertonic and hypotonic stress are the possible reasons for damage to a CD34 + CD38 - cell during the cryopreservation procedure. (ulster.ac.uk)

Ten percent of CVID patients have low B cell counts and 20-30 % develop autoimmune conditions, mainly idiopathic thrombocytopenic purpura (ITP), autoimmune haemolytic anaemia (AIHA) and thyroiditis. (ucl.ac.uk)
The aim of this study was to investigate why some CVID patients have low B cell numbers. (ucl.ac.uk)
B cells from healthy donors were incubated with patients' sera and stained with anti- human CD19, - IgM and -IgG antibodies. (ucl.ac.uk)
Thirty-six CVID patients with low B cell numbers, autoimmune manifestation or both were screened. (ucl.ac.uk)
B cell phenotypes and BAFF serum levels were used to select patients for sequencing BAFF, or BAFF receptor (BAFF-R) for possible mutations. (ucl.ac.uk)
The surface expression of BAFF-R on B cells from patients with rare polymorphisms showed no major impairment compared to healthy individuals. (ucl.ac.uk)
After UMSC transplantation (UMSCT), the frequencies of Tregs and CD4 + memory T cells were significantly increased, and the frequencies of T helper (Th) 17 and CD4 + naive T cells were significantly decreased in peripheral blood (PB) of psoriasis patients. (nature.com)
Background: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis complex (TSC) entered into the TuberOus SClerosis registry to increase disease Awareness (TOSCA). (gencat.cat)
Methods The present multicenter retrospective study investigated clinical and molecular characteristics in 114 patients with unresectable MCC at baseline before treatment with ICI for their association with therapy response (best overall response, BOR). (merkelcell.org)
To explore this in peripheral samples, we characterized CD8+ T cell gene expression across a cohort of patients with MM receiving anti-PD-1 alone (sICB) or in combination with anti-CTLA-4 (cICB). (ox.ac.uk)
Early samples from patients with durable clinical benefit demonstrated overexpression of T cell receptor-encoding genes. (ox.ac.uk)
The 6-month clinical response to ICB in patients with MM is associated with the large CD8+ T cell clone count 21 d after treatment and agnostic to clonal specificity, suggesting that post-ICB peripheral CD8+ clonality can provide information regarding long-term treatment response and, potentially, facilitate treatment stratification. (ox.ac.uk)
Early enzymologic studies showed that cultured fibroblasts from patients with I-cell disease were deficient in numerous lysosomal enzymes. (medscape.com)

METHODS: Corneal transplant procedures registered in the European Cornea and Cell Transplantation Registry were identified. (lu.se)
Preoperative donor and recipient characteristics, indication and reason for transplantation, and surgical techniques were analyzed. (lu.se)
Treatment is often supportive, but Janus kinase 2 (JAK2) inhibitors, such as ruxolitinib , fedratinib , or pacritnib, may decrease symptoms and stem cell transplantation may be curative. (msdmanuals.com)

By means of infrared (IR) spectroscopy, several characteristics can be measured simultaneously. (ru.nl)

The fungal cell membrane is made up of unique sterol and ergosterol. (microbiologynote.com)
Furthermore, the results illustrated that changing geometrical and mechanical properties of the membrane by 45% have a negligible effect on the natural frequency of the fuel cell. (irost.ir)
6] Diloyan G, Sobel M, Das K, Hutapea P. Effect of mechanical vibration on platinum particle agglomeration and growth in Polymer Electrolyte Membrane Fuel Cell catalyst layers. (irost.ir)
Effect of vibrations on performance of polymer electrolyte membrane fuel cells. (irost.ir)
10] Wang X, Wang S, Chen S, Zhu T, Xie X, Mao Z. Dynamic response of proton exchange membrane fuel cell under mechanical vibration. (irost.ir)
14] Ahn S, Koh H, Lee J, Park J. Dependence between the vibration characteristics of the proton exchange membrane fuel cell and the stack structural feature. (irost.ir)
DNA can be localized to a particular cell region, as in the nucleoid of a prokaryotic cell, or it can be contained inside another membrane, such as the nucleus of eukaryotes. (jove.com)

Prior to this, laboratory research on adult stem cells first began over 40 years ago. (cellmedicine.com)
Characteristics of a laboratory scale immobilized cell bioreactor for acidification of milk. (ncsu.edu)

To explore the second hypothesis, serum levels of the B cell activating factor BAFF were analyzed. (ucl.ac.uk)
And all responders showed significant increases in Tregs and CD4 + memory T cells, and significant decreases in Th17 cells and serum IL-17 level after UMSCT. (nature.com)

MCPyV, Merkel cell polyomavirus. (cdc.gov)
The immune system plays an important role in preventing the development and progression of Merkel cell carcinoma (MCC). (merkelcell.org)
Background Based on its viral-associated or UV-associated carcinogenesis, Merkel cell carcinoma (MCC) is a highly immunogenic skin cancer. (merkelcell.org)
While neither tumor Merkel cell polyomavirus nor tumor PD-L1 status showed a correlation with therapy response, treatment with anti-PD-1 antibodies was associated with a higher probability of disease control than treatment with anti-PD-L1 antibodies. (merkelcell.org)
The authoritative source on Merkel cell carcinoma. (merkelcell.org)

In conclusion, dermal exposure to unused semi-synthetic MWF penetrates the normal skin, induces mast cell accumulation in the skin, produces hypertrophy of the sebaceous glands, and may affect females more than males. (cdc.gov)

The RPE is a monolayer of cells between the neural retina and choroidal blood supply, and is critically important for photoreceptor function. (arvojournals.org)

By definition, "adult" stem cells are present from the moment of birth, and thereafter throughout the remainder of an individual's lifetime. (cellmedicine.com)
Adult" stem cells are also sometimes called "somatic" stem cells, or "master" cells. (cellmedicine.com)
This phenomenon will be described in more detail later, as new discoveries in the versatility and "plasticity" of adult stem cells are continually being made. (cellmedicine.com)
In 2004, NIH allocated $ 190 million of its budget to adult stem cell research, and $ 25 million to embryonic stem cell research. (cellmedicine.com)
The role of adult stem cells in medical science is well established. (cellmedicine.com)
Adult" stem cell therapy is not new. (cellmedicine.com)

Effectively targeting cancer stem cells to treat cancer has great therapeutic prospects. (nih.gov)
Hematopoietic stem cells derived from fetal liver have promising therapeutic potential for allotransplantation but require a specific protocol to minimize the damage produced by cryopreservation procedures. (ulster.ac.uk)

J Cell Biol (1994) 127 (4): 1085-1096. (rupress.org)
J. Cell Biol. (rupress.org)
Am J Respir Cell Mol Biol 10:253-258. (cdc.gov)

Summary: The effect of pTR2030 on phage DNA injection, transfection, release of progeny phage, and cell death was evaluated for a number of lactococcal phages. (ncsu.edu)

Methods: Expression of postulated stem cell markers aldehyde dehydrogenase (ALDH), CD44, and CD133 was analyzed in UM cell lines and primary UM short-term cultures (STCs) established from tumor samples. (whiterose.ac.uk)

MSCs are multipotent cells characterized by their regenerative capabilities and immunomodulatory properties. (nature.com)

We analyzed the morphological features of dying cells in the developing axial structures of 5 human embryos between 5 and 8 weeks of postovulatory age. (karger.com)
Clarke, P.G.H. (1990) Developmental cell death: Morphological diversity and multiple mechanisms. (karger.com)

Chu-Wang, I.W., R.W. Oppenheim (1978) Cell death of motoneurons in the chick embryo spinal cord. (karger.com)
Cells closely resembling epithelia constitute the first specific cell type in a mammalian embryo. (rupress.org)
An embryonic stem cell is derived from a group of cells called the inner cell mass, which is part of the early (4 to 5 day old) embryo called the blastocyst. (cellmedicine.com)
In order to create an embryonic stem cell line, the destruction of the embryo is required. (cellmedicine.com)

I-cell disease fibroblasts were subsequently discovered to be able to internalize and use lysosomal enzymes produced by normal cells, whereas normal or other lysosomal disease fibroblasts were incapable of internalizing lysosomal enzymes secreted by the I-cell disease fibroblasts. (medscape.com)

Somatic mutations in the BRAF gene have been identified in the Langerhans cells of about half of individuals with Langerhans cell histiocytosis. (medlineplus.gov)
Somatic gene mutations are acquired during a person's lifetime and are present only in certain cells. (medlineplus.gov)

This ulcerated nodule of localized primary cutaneous CD30+ anaplastic large cell lymphoma is relatively nonspecific in appearance. (medscape.com)
PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)

The cell is the basic unit of every living organism on this planet. (elitetutorslab.com)

The BRAF gene provides instructions for making a protein that is normally switched on and off in response to signals that control cell growth and development. (medlineplus.gov)
Four solar cells were prepared with 50, 100, 200 and 400 nm-thick CdSe layers to reveal the formation, growth, composition, structure and photoactivity of the CdTe x Se 1₋x alloy with respect to the degree of Se diffusion. (osti.gov)

Results: We demonstrate that expression of ALDH, CD44, and CD133 does not select for a subpopulation of stem-like cells in either UM cell lines or UM STCs. (whiterose.ac.uk)
The results showed that the expression of GRP78 was higher in PanINs and PDGs than in normal ductal cells in TG mice, suggesting that GRP78 plays important roles in the maintenance of the atypical ductal lesions. (diabetesjournals.org)
The expression of GRP78 was higher in β cells than in alpha and delta cells in both mice. (diabetesjournals.org)
As the substrate stiffness increased, HCC cells exhibited high proportion of cells with CD133(+)/EpCAM(+), high expression levels of CD133, EpCAM, Nanog and SOX2, greater self-renewing ability and oxaliplatin resistance. (oncotarget.com)
Additionally, mTOR inhibitor suppressed the mTOR phosphorylation level and expression levels of p-4E-BP and SOX2 in HCC cells grown on higher stiffness substrate, as well as depressed their stemness properties significantly, favoring a regulating role of mTOR signaling pathway in matrix stiffness-mediated effects on stemness. (oncotarget.com)

However, the details of in vivo distribution of GRP78, particularly in endocrine cells outside β cells, are still remain elusive. (diabetesjournals.org)

In this study, we conducted staining experiments for GRP78 in the pancreatic sections of well-matured mice to explore the relation between endocrine cells and intra-islet ducts. (diabetesjournals.org)
11 The regulatory effect of MSCs on T cells has also been demonstrated in mice models of autoimmune disease such as rheumatoid arthritis and sjogren syndrome (SS). (nature.com)
To visualize the glutamatergic neurons, we used MS-DBB slices from transgenic mice in which the green fluorescent protein is expressed specifically by vesicular glutamate transporter 2-positive neurons and characterized their properties using whole-cell patch-clamp technique. (jneurosci.org)

It also helps to inform cell engineering and regenerative medicine research. (sanger.ac.uk)

The center of a cell is called a nucleus. (mindmeister.com)

Two new papers from the Human Cell Atlas shed new light on the types and traits of immune cells that can be found in the human body, from developmental stages to adulthood. (sanger.ac.uk)
Two new papers from the Wellcome Sanger Institute, the University of Cambridge and collaborators have created open-access atlases of the immune cells in the human body. (sanger.ac.uk)
The team used data from the other Human Cell Atlas study** to prove that these particular immune cells are not found in adults. (sanger.ac.uk)
The team developed a database and algorithm that automatically classifies different cell types, called CellTypist, to handle the large volume and variation of immune cells. (sanger.ac.uk)

In Langerhans cell histiocytosis, excess immature Langerhans cells usually form tumors called granulomas. (medlineplus.gov)

3 An up-to-date list of WHO International Standards and Reference Reagents is available at http://www.who.int/bloodproducts/catalogue/en/ (accessed 28 February 2013). (who.int)

Cytoplasm7

Tumor cells3

Renal9

Proliferation4

Biophysical characteristics1

Vibrational1

Bone marrow10

Clinical characteristics4

Differentiation5

Phenotype1

Effector2

Fetal stem cells3

Cancer stem cell characteri1

Demographic1

Antigen3

Dendritic1

Epithelial2

Mesenchymal3

RBCs1

Flow Cytometry2

Assay2

Melanoma1

Umbilical cord4

Isolates2

Electron6

Organs4

Macrophages3

Tissue5

Tissues10

Apoptosis2

Antigens2

Exhibit1

MicroRNA2

Hypotonic2

Patients13

Transplantation3

Several characteristics1

Membrane7

Laboratory2

Serum2

Merkel5

Induces1

Neural1

Adult6

Therapeutic2

Biol3

Progeny1

Methods1

Multipotent1

Morphological2

Embryo4

Fibroblasts1

Somatic2

Cutaneous2

Living organism1

Growth2

Expression5

Vivo1

Mice3

Regenerative1

Nucleus1

Immune cells4

Tumors1

Catalogue1