Shal-related subfamily, member 3) voltage-gated potassium channels Nitric oxide synthase TRPC5 channel Ric8a Frq modulates Ca2+ entry through a functional interaction with the α1 voltage-gated Ca2+-channel subunit. (wikipedia.org)
This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. (nih.gov)
Homo sapiens potassium voltage-gated channel subfamily A regulatory beta subunit 2 (KCNAB2), transcript variant 5, mRNA. (ucsc.edu)
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. (ucsc.edu)
Voltage-gated3
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. (nih.gov)
The role of the voltage-gated potassium channel, Kv2.1 in prostate cancer cell migration. (nih.gov)
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. (nih.gov)
Shaker2
Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). (nih.gov)
Belongs to the shaker potassium channel beta subunit family. (ucsc.edu)
Subunit1
Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. (ucsc.edu)
SIMILARITY2
channel properties depend on the type of alpha subunits that are part of the channel (By similarity). (nih.gov)
Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation (By similarity). (nih.gov)
Member1
This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. (nih.gov)
Type1
Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) is an intracellular Ca2+ release channel important for a number of fundamental cellular functions. (bvsalud.org)
Activation2
Homotetrameric channels display rapid activation and slow inactivation (PubMed:2347305). (nih.gov)
To determine whether GOF in ITPR1 itself has pathological ramifications, we employed a newly developed mouse model expressing an ITPR1 mutation in the gating domain of the channel, D2594K, that markedly increased the channel's sensitivity to activation by IP3. (bvsalud.org)
Kv4.31
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. (nih.gov)
Kv4.22
In mammalian hippocampal pyramidal neurons, this current is carried primarily by ion channels comprising Kv4.2 α-subunits. (nih.gov)
Here, we describe the role of p38 kinase phosphorylation of a C-terminal motif in Kv4.2 in modulating hippocampal neuronal excitability and behavioral seizure strength. (nih.gov)
Neuronal1
Here, we review the diverse molecular mechanisms that have been shown or proposed to underlie the functional diversity of native neuronal IA channels. (nih.gov)
Cell membrane2
Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. (nih.gov)
Cell membrane glycoproteins that form channels to selectively pass chloride ions. (lookformedical.com)
Neurons2
These channels occupy the somatodendritic domains of these principle excitatory neurons and thus regulate membrane voltage relevant to the input-output efficacy of these cells. (nih.gov)
The syndrome is caused by changes in the structure and function of certain cardiac ion channels and reduced expression of Connexin 43 (Cx43) in the Right Ventricle (RV), predominantly in the Right Ventricular Outflow Tract (VSVD), causing electromechanical abnormalities. (bvsalud.org)