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  • Gene
  • To use genetic variants in the CETP gene to assess potential risks and benefits of lifelong lower CETP activity on CVD and other outcomes. (ovid.com)
  • 1.0 x 10 10 gene copies) containing CETP with a liver-specific thyroxine binding globulin (TBG) promoter or control virus. (ahajournals.org)
  • The CETP gene is located on the sixteenth chromosome (16q21). (wikipedia.org)
  • In contrast, a polymorphism (I405V) of the CETP gene leading to lower serum levels has also been linked to exceptional longevity and to metabolic response to nutritional intervention. (wikipedia.org)
  • Genes
  • Combined exposure to variants in the genes that encode the targets of CETP inhibitors and statins was associated with discordant reductions in LDL-C and apoB (show APOB ELISA Kits ) levels and a corresponding risk of cardiovascular events that was proportional to the attenuated reduction in apoB (show APOB ELISA Kits ) but significantly less than expected per unit change in LDL-C. (antibodies-online.com)
  • Studies in women reported associations between polymorphisms in ESR1 , LPL and CETP genes and MetS. (mdpi.com)
  • Our aim was to evaluate the association between variants in ESR1 , LPL and CETP genes with MetS and its components. (mdpi.com)
  • In conclusion, our results show the involvement of the variants of ESR1 , LPL and CETP genes in metabolic events related to MetS or some of its features. (mdpi.com)
  • statins
  • Based on results from the study with a relatively large sample size, CETP may be the only detectable locus with common genetic variants that influence HDL (show HSD11B1 ELISA Kits )-C response to statins substantially in individuals of European descent. (antibodies-online.com)
  • antibody
  • The following antibody was used in this experiment: CETP Polyclonal Antibody from Thermo Fisher Scientific, catalog # PA5-29090, RRID AB_2546566. (thermofisher.com)
  • Pfizer
  • At its recent research and development meeting, Pfizer highlighted T/A and CETP research as the most important new development in CV medicine in years. (pharmamanufacturing.com)
  • outcome
  • There are theoretical reasons why CETP inhibitors may not deliver their promise and this underlines the need for properly conducted clinical outcome trials. (bjcardio.co.uk)