• Here, the authors describe a 50-year-old male with an aggressive ENB, initially treated with resection and chemotherapy/radiation, who developed multiple thoracic and lumbar spinal metastases. (thejns.org)
  • This article highlights the specific symptoms, causes, and treatments of central canal stenosis in the neck (cervical), upper back (thoracic), and lower back (lumbar) regions. (spine-health.com)
  • Spine conditions occur in the cervical (neck), thoracic (mid-back) or lumbar (low back). (sanramonmedctr.com)
  • MRI of the spine showed a spinal cord compression due to bone and epidural tumoral lesions of the posterior wall of the D1 to D5 thoracic vertebras ( Figure 1 ). (scirp.org)
  • T1 and T2 magnetic resonance imaging (MRI) images show cord compressing tumoral mass at D1 to D5 thoracic vertebras. (scirp.org)
  • MRI of the spine showed multifocal, longitudinally extensive, partially enhancing lesions of the central thoracic spinal cord and gray matter of the conus medullaris, with a single cervical level of canal stenosis with partial cord compression (presumably chronic and not acute). (cdc.gov)
  • Typically, stenosis is seen in up to 80% of people above 60 years of age, with an estimated 5% having coexisting cervical and lumbar stenosis (also called tandem spinal stenosis). (spine-health.com)
  • About 20% of the patients I see with cervical spinal stenosis also have lumbar stenosis, which is a narrowing of the spinal canal in the lower part of the back. (parkview.com)
  • If you have cervical instability and deformity as the result of odontoid pannus, but are not having neurological compression, the recommended treatment is cranio-cervical fusion to stabilize the joints. (upmc.com)
  • Atlantoaxial instability is an uncommon condition of dogs in which there is abnormal movement in the neck , between the atlas (first cervical vertebra) and axis (second vertebra). (acvs.org)
  • This instability allows abnormal bending between the two bones, which causes compression of the spinal cord . (acvs.org)
  • Views during flexion, as tolerated by the patient, show dynamic instability of the entire cervical spine. (merckmanuals.com)
  • Indications for treatment of atlantoaxial subluxation include pain, neurologic deficits, and potential spinal instability. (merckmanuals.com)
  • Depending upon the extent and level of fusion, some people may develop cervical or craniocervical instability and require fusion surgery to prevent serious injury. (pediatriconcall.com)
  • Osseous destruction is often associated with mechanical instability, intractable pain, radiculopathy, and symptoms of cord compression. (ajnr.org)
  • The atlanto-axial instability is defined as a result in spinal cord compression4,5. (bvsalud.org)
  • A computed tomography (CT) scan of the cervical spine makes cross-sectional pictures of the neck. (medlineplus.gov)
  • These include neck and shoulder pain, suboccipital pain and headache, radicular symptoms, and cervical spondylotic myelopathy (CSM). (medscape.com)
  • The spinal cord descends from the brain, traveling down through the neck and ending at the upper part of the low back. (spine-health.com)
  • Spinal cord compression in the neck may cause bending or twisting of blood vessels that supply the spinal cord and the brain. (spine-health.com)
  • Central stenosis of the cervical spine may cause neck, shoulder, and/or arm pain. (spine-health.com)
  • Cervical myelopathy occurs due to compression of the cervical spinal cord in the neck. (apollohospitals.com)
  • Cervical myelopathy is mostly caused due to several factors like degeneration or rupture of a cervical disc, slipped disc, neck dislocation or fracture, traumatic cervical spine injury, compression and tumors in the spinal cord and other auto immune diseases that include multiple sclerosis, myelitis and neuromyelitisoptica. (apollohospitals.com)
  • Odontoid pannus can also develop as a result of severe trauma to the neck, at the second cervical vertebra. (upmc.com)
  • Spinal stenosis, both neck and lower back, are common for people age 60 and older. (mainlinehealth.org)
  • Spinal stenosis in the neck can compress the spinal cord and lead to total body weakness or even paralysis. (mainlinehealth.org)
  • Stenosis is caused by the narrowing of the open spaces within your spine that puts pressure on the spinal cord and the nerves that travel along the spine, particularly in the cervical and lumbar regions of the spine-neck area and lower back, respectively. (mainlinehealth.org)
  • These patients are experiencing compression in the spinal cord and/or neck, which often leads to uncomfortable or concerning symptoms. (parkview.com)
  • When should someone seek a consult about their spinal/neck pain? (parkview.com)
  • These conditions can be addressed surgically at the same time, but cervical spinal stenosis is the priority, since it affects all downstream functions with the nerves from the neck, down. (parkview.com)
  • A cervical MRI (magnetic resonance imaging) scan uses energy from strong magnets to create pictures of the part of the spine that runs through the neck area (cervical spine). (ucsfhealth.org)
  • The solitary cervical neurofibroma was treated surgically in a single stage through laminoplasty and excision of the intradural tumor along with that of the neck component. (thieme-connect.com)
  • In children, lymphoma may present as one or more painless masses, often in the neck, accompanied by signs and symptoms resulting from local compression, as well as signs and symptoms of systemic disturbances, such as fever and weight loss. (aafp.org)
  • Injuries and disorders can put pressure on the spinal cord, causing back or neck pain, tingling, muscle weakness, and other symptoms. (msdmanuals.com)
  • Basilar Invagination is a relatively rare condition that occurs at the junction of the skull and the upper neck in which the upper portion of the second cervical vertebra migrates upward and posteriorly into the intracranial space. (uclahealth.org)
  • There are muscles in your head and neck that help to keep the head balanced upon your spinal column. (raymondsheridandds.com)
  • Cervical compression occurs when pressure is put on the spinal cord in the neck area. (raymondsheridandds.com)
  • Most of the CM/SM cases that the author encounters are presented for signs referable to the cervical region (e.g., neck pain, scratching activity) and subtle signs of central vestibular dysfunction are apparent on neurologic examination. (vin.com)
  • A simple model consisting of four risk factors can help surgeons to predict the risk of complications after surgery for cervical spondylotic myelopathy (CSM)-a common condition causing compression of the spinal cord in the neck, reports a study in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer. (news-medical.net)
  • Atlantoaxial subluxation is usually asymptomatic but may cause vague neck pain, occipital headache, or occasionally intermittent (and potentially fatal) cervical spinal cord compression. (merckmanuals.com)
  • Inclusion criteria: (a) Patients with cervical radiculopathy, which can be felt on one or both sides of the body and may or may not be accompanied by neck pain for more than 3 months, (b) presence of paresthesia or numbness, weakness, or altered reflex in the dermatome or myotome of the cervical nerve root C2-C8. (who.int)
  • Surgical indications for cervical spondylotic myelopathy remain somewhat controversial, but most clinicians recommend operative therapy over conservative therapy for moderate-to-severe myelopathy. (medscape.com)
  • At UPMC, the preferred surgical treatment for spinal cord or brainstem compression caused by odontoid pannus, rheumatoid pannus, or synovial cyst is the Endoscopic Endonasal Approach (EEA) to decompress the brainstem and spinal cord. (upmc.com)
  • Surgical decompression is necessary if the spinal cord and brainstem are compressed. (upmc.com)
  • Revisiting the surgical corridors for cervical type IIb-c dumbbell neurofibroma: A series of two unconventional approaches and review of literature. (thieme-connect.com)
  • 5 Asazuma T, Toyama Y, Maruiwa H, Fujimura Y, Hirabayashi K. Surgical strategy for cervical dumbbell tumors based on a three-dimensional classification. (thieme-connect.com)
  • Spinal nerves schwannomas: experience on 367 cases-historic overview on how clinical, radiological, and surgical practices have changed over a course of 60 years. (thieme-connect.com)
  • Surgical management of dumbbell tumors of the cervical spine. (thieme-connect.com)
  • Surgical principles for spinal and paraspinal neurofibromas. (thieme-connect.com)
  • 12 Ito K, Aoyama T, Miyaoka Y, Horiuchi T, Hongo K. Surgical strategies for cervical spinal neurinomas. (thieme-connect.com)
  • Surgical treatment is reserved for patients with symptoms refractory to non-operative management, neurological deficit, or severe spinal cord compression. (uclahealth.org)
  • His specialist interest includes assessment, non-surgical and surgical treatment of adult spinal conditions. (nuffieldhealth.com)
  • Surgical repair of spinal metastases from renal origin is often complicated by excessive bleeding. (ajnr.org)
  • Anterior surgical decompression and stabilization are the treatments of choice for radiation-resistant metastatic spinal tumors, resulting in improved neurologic function and pain reduction in more than 80% of patients (4, 5) . (ajnr.org)
  • Although sarcoid management typically involves immune suppression, in cases of active cord compression surgical intervention is warranted. (surgicalneurologyint.com)
  • 1 ] Contrary to conventional sarcoid treatment, surgical resection is recommended for spinal decompression where patients have significant neurological deficits. (surgicalneurologyint.com)
  • How often do deep surgical site infections occur after spinal surgery, and what are the risk factors for recurrence? (medscape.com)
  • Predictive Model for Cervical Alignment and Malalignment Following Surgical Correction of Adult Spinal Deformity. (medscape.com)
  • The Influence of Diabetes on Surgical Outcomes in Cervical Myelopathy. (medscape.com)
  • He looks after patients with degenerative, traumatic, tumour and spinal deformity problems within the whole spine. (nuffieldhealth.com)
  • Deformity Angular Ratio Describes the Severity of Spinal Deformity and Predicts the Risk of Neurologic Deficit in Posterior Vertebral Column Resection Surgery. (medscape.com)
  • Validity, Reliability, and Responsiveness of SRS-7 as an Outcomes Assessment Instrument for Operatively Treated Patients With Adult Spinal Deformity. (medscape.com)
  • A 20-year-old female with HCS and progressive symptomatic BI, initially managed with posterior fossa decompression and occipital to cervical fusion, subsequently required cranial vault expansion due to symptomatic shifting of her cranium secondary to POCS. (thejns.org)
  • After endonasal decompression of the neural structures, you will need a cranio-cervical fusion to prevent recurrence and promote stability of the joints to avoid further neurological deterioration. (upmc.com)
  • Nevertheless, in the presented case the patient had an isolated, extramedullary compressive cervical sarcoid mass warranting operative decompression. (surgicalneurologyint.com)
  • Cervical spondylosis is a common degenerative condition of the cervical spine. (medscape.com)
  • However, only a small percentage of patients with radiographic evidence of cervical spondylosis are symptomatic. (medscape.com)
  • Many of the treatment modalities for cervical spondylosis have not been subjected to rigorous, controlled trials. (medscape.com)
  • Cervical spondylosis is the result of disk degeneration. (medscape.com)
  • Ossification of the posterior longitudinal ligament, a condition often seen in certain Asian populations, can occur with cervical spondylosis. (medscape.com)
  • It is triggered by the development of degenerative changes - so-called cervical spondylosis, which affects bone, ligamentous and cartilaginous structures and leads to static or dynamic compression of the spinal cord and its vessels. (muni.cz)
  • Surgery is indicated in localised compression as long as there is some hope of regaining function. (wikipedia.org)
  • Surgery is advocated for cervical radiculopathy in patients who have intractable pain, progressive symptoms, or weakness that fails to improve with conservative therapy. (medscape.com)
  • 2014. doi:10.1016/c2009-0-42800-9 Spine surgery in people over 65 years is most commonly performed for treating spinal stenosis. (spine-health.com)
  • However, if you suffer from spinal cord or brainstem compression, then we recommend surgery to decompress these vital neural elements. (upmc.com)
  • In severe cases, surgery may be required to create additional space for the spinal cord and nerves. (mainlinehealth.org)
  • Laminectomy or Spinal Fusion surgery may be required if the nonsurgical treatments have not helped. (mainlinehealth.org)
  • If a patient shows evidence of cervical stenosis on an MRI, but isn't experiencing significant symptoms and/or isn't a good candidate for surgery, the typical recommendation for treatment is physical management through physical therapy, though this will not address the spinal compression. (parkview.com)
  • A cervical MRI may also be done before spinal surgery. (ucsfhealth.org)
  • We report a rare case of adult Langerhans cell histiocytosis in the dorsal spine causing a spinal cord compression associated with a pulmonary process treated by surgery, radiotherapy and systemic therapy with good evolution. (scirp.org)
  • Surgery usually involves the removal of bone that is causing the compression and stabilization with a fusion. (uclahealth.org)
  • If the spinal cord is compressed, surgery to relieve compression is required. (pediatriconcall.com)
  • In years 2014 and 2015 he enhanced his experience in complex spinal surgery with two prestigious fellowships: National Spinal Fellowship and National British Orthopaedic Association Fellowship in Spinal Surgery. (nuffieldhealth.com)
  • A control group of 10 patients with 11 spinal metastases of renal origin underwent surgery without embolization. (ajnr.org)
  • Do Caucasians and East Asians have Different Outcomes Following Surgery for the Treatment of Degenerative Cervical Myelopathy? (medscape.com)
  • Who are the Best Candidates for Decompressive Surgery and Spine Stabilization in Patients With Metastatic Spinal Cord Compression? (medscape.com)
  • Exclusion criteria: (a) Patients who previously had cervical spine surgery. (who.int)
  • Children who had undergone cervical spine surgery or who had disea- ses not associated with this syndrome were excluded. (bvsalud.org)
  • The median survival of patients with metastatic spinal cord compression is about 12 weeks, reflecting the generally advanced nature of the underlying malignant disease. (wikipedia.org)
  • This treatment went through October 2008, with Powell undergoing testing, including an October 2007 EMG that showed rightS 1 radiculopathy and chronic cervical radiculopathy. (justia.com)
  • The most common causes of cord compression are tumors, but abscesses and granulomas (e.g. in tuberculosis) are equally capable of producing the syndrome. (wikipedia.org)
  • Tumors that commonly cause cord compression are lung cancer (non-small cell type), breast cancer, prostate cancer, renal cell carcinoma, thyroid cancer, lymphoma and multiple myeloma. (wikipedia.org)
  • Spinal nerve root tumors can arise throughout the spine and at multiple levels, likely representing plexiform neurofibromas that grow from the nerve root into the intraspinal space either intradurally or epidurally and exit through the neural foramen, producing a dumbbell-shaped appearance. (thieme-connect.com)
  • 8 Ozawa H, Kokubun S, Aizawa T, Hoshikawa T, Kawahara C. Spinal dumbbell tumors: an analysis of a series of 118 cases. (thieme-connect.com)
  • Brain and Spinal Tumors: Primary and Secondary. (thieme-connect.com)
  • The spinal cord may be compressed by bone, blood (hematomas), pus (abscesses), tumors (cancerous or not), or a ruptured or herniated disk. (msdmanuals.com)
  • Embolization has been used as a presurgical maneuver in the treatment of a variety of primary and secondary spinal tumors (6-22) . (ajnr.org)
  • The most common horse vertebral issues seen over a decade at one diagnostic lab were wobbler syndrome, fracture/subluxation, and abnormal spinal curvature. (thehorse.com)
  • Distribution of diseases included equine cervical vertebral stenotic myelopathy (n=224), fracture/subluxation (n=123), abnormal spinal curvature (n=51), osteomyelitis (n=13), intervertebral disc disease (n=7), congenital vertebral anomaly (n=5), and neoplasia (n=3). (thehorse.com)
  • Odontoid pannus is abnormal tissue that grows in the region of the odontoid process, a toothlike projection at the back of the second cervical vertebra. (upmc.com)
  • All can contribute to impingement on pain-sensitive structures (eg, nerves, spinal cord), thus creating various clinical syndromes. (medscape.com)
  • A positive Hoffman's sign may indicate that you have a neurological or nervous system condition that affects the cervical spine nerves or brain. (healthline.com)
  • A bundle of nerves descends from the bottom of the spinal cord to form the cauda equina. (spine-health.com)
  • Other causes include bone disease that causes an excess of bone growth of around the spinal nerves as in osteoarthritis. (mainlinehealth.org)
  • Cauda Equina Syndrome Cauda equina syndrome occurs when the bundle of nerves that extends from the bottom of the spinal cord is compressed or damaged. (msdmanuals.com)
  • SEPs provide information concerning the integrity of the pathway through the brain, brain stem, spinal cord, dorsal roots, and peripheral nerves. (medscape.com)
  • The U.S. Department of Labor defines CTS as a disorder associated with the peripheral nervous system, which includes nerves and ganglia located outside the spinal cord and brain. (cdc.gov)
  • Predictors of symptomatic myelopathy in degenerative cervical spinal cord compression. (spine-health.com)
  • Patients generally become symptomatic when the displaced vertebral segment causes sufficient pressure on the upper spinal cord or lower portion of the brainstem. (uclahealth.org)
  • Treatment includes symptomatic measures and cervical immobilization, usually beginning with a rigid cervical collar. (merckmanuals.com)
  • This retrospective study included 18 consecutive patients with 21 symptomatic spinal metastases who underwent preoperative spinal angiography and embolization at our institution between October 1995 and August 1999. (ajnr.org)
  • Acute compression may follow subacute and chronic compression, especially if the cause is abscess or tumor. (wikipedia.org)
  • The authors performed targeted exome sequencing on both the resected primary tumor and biopsied spinal metastases, which revealed 12 total variants of unknown clinical significance in genes associated with the PI3K/AKT/mTOR pathway, chromatin remodeling, DNA repair, and cell proliferation. (thejns.org)
  • A spinal tumor often presents with signs and symptoms of spinal cord compression. (aafp.org)
  • Rarely, a tumor within the spinal cord causes compression. (msdmanuals.com)
  • When there is no neurological compromise, the recommended treatment is cranio-cervical fusion to stabilize the joints. (upmc.com)
  • We present a case of brucellar spondylitis with paravertebral mass in the cervical segment that resulted in neurological deficits. (who.int)
  • Physical examination revealed nothing but cervical spine tenderness at C4-C6, while neurological examination revealed a decrease in strength in the right biceps and triceps, with attenuation of their reflexes. (who.int)
  • Can cause compression of the spinal cord potentially resulting in worsening weakness and sensory problems in upper and lower limbs, and in extreme cases resulting in major neurological deficit. (advancedneurosurgery.co.uk)
  • Myelopathy is a clinical diagnosis with localization of the neurological findings to the spinal cord, rather than the brain or the peripheral nervous system, and then to a particular segment of the spinal cord. (bvsalud.org)
  • A change in the atlanto-axial alignment in children with Down syndrome may be associated with pain, neurological disorders, high spinal cord compression and sudden death. (bvsalud.org)
  • The change in alignment of the atlanto-axial and dysmorphic changes such as superior eyelid segment can be associated with pain, neurological slope, single palmar crease, small mouth, small disorders, high spinal cord compression and, in ears, protruding tongue and greater space between some cases, can cause sudden death. (bvsalud.org)
  • By far, evidence of cervical dysfunction and cerebellovestibular dysfunction are the most common and are often both present (e.g., multifocal CNS disease). (vin.com)
  • Notably, approximately 81% of spinal sarcoid lesions are intramedullary in location (2). (surgicalneurologyint.com)
  • AFM is an illness that's characterized by the sudden onset of flaccid weakness in one or more extremities and also by distinct longitudinal gray matter lesions in the spinal cord. (cdc.gov)
  • [ 6 , 9 ] Dynamic factors relate to the fact that normal flexion and extension of the cord may aggravate spinal cord damage initiated by static compression of the cord. (medscape.com)
  • During flexion, the spinal cord lengthens, resulting in it being stretched over ventral osteophytic bars. (medscape.com)
  • Symptoms can become worse with flexion of the head, which even further drapes the spinal cord over the upper portion of C2. (uclahealth.org)
  • The ligamentous laxity and It is imperative that health care professionals generalized hypotonia are characteristics that be aware about the presence of this condition, since contribute to the change of alignment in the atlanto- physical activity involving cervical flexion may cause axial segment in children with Down syndrome1,2. (bvsalud.org)
  • Cervical spondylotic myelopathy occurs as a result of several important pathophysiological factors. (medscape.com)
  • thus, patients with congenitally narrowed spinal canals (10-13 mm) are predisposed to developing cervical spondylotic myelopathy. (medscape.com)
  • Imaging tests can find other abnormalities in your spine, such as spinal cord compression or osteoarthritis . (healthline.com)
  • Symptoms of cervical-spinal abnormalities develop in approximately 60 to 80 percent of patients with rheumatoid arthritis. (upmc.com)
  • Urgency of treatment is generally based on symptoms or presence of cord abnormalities on MRI in susceptible patients. (merckmanuals.com)
  • Cervical vertebral stenotic myelopathy (CSM) occurs as either a static or dynamic form in young horses and described as a multifactorial disease when stenosis is observed in older horses it is primarily due to osteoarthritis of the articular process joints. (ivis.org)
  • When acute it can cause a medical emergency independent of its cause, and require swift diagnosis and treatment to prevent long-term disability due to irreversible spinal cord injury. (wikipedia.org)
  • Dexamethasone (a potent glucocorticoid) in doses of 16 mg/day may reduce edema around the lesion and protect the cord from injury. (wikipedia.org)
  • Treatment of Spinal Cord Injury - Similar to trauma, surgeons specifically work on the spinal cord. (sanramonmedctr.com)
  • Whilst playing at home he fell sustaining a minor cervical hyperextension injury. (bmj.com)
  • The most common cause of a spinal hematoma is an injury, but many other conditions can cause hematomas. (msdmanuals.com)
  • The severity of the injury to the spinal cord depends both on the amount of pressure, and the duration of the condition. (acvs.org)
  • Some children may have spinal cord injury after minor trauma due to high-risk patterns of cervical fusion. (pediatriconcall.com)
  • Where are the most common sites of cervical spine injuries? (brainscape.com)
  • He also opined that Powell was unable to use her hands and fingers for more than one-third of each day due to nerve problems stemming from her spinal injuries. (justia.com)
  • At the UCLA Health Spine Center, our experts diagnose, manage and treat all spinal injuries and conditions. (uclahealth.org)
  • This stock medical-legal exhibit depicts an initial cut-away view revealing widespread cervical spine injuries creating compression of the spinal cord. (smartimagebase.com)
  • Repetitive strain injuries (RSI), which include several musculoskeletal disorders and nerve compression injuries, are associated with performance of repetitive and forceful tasks. (cdc.gov)
  • This condition can be an additional contributing source of severe anterior cord compression. (medscape.com)
  • While lumbar spine involvement is the most common, cervical involvement is a rare, but more severe, complication, accounting for 8.3% of cases of vertebral osteomyelitis in a recent study [4]. (who.int)
  • Overview of Spinal Cord Disorders Spinal cord disorders can cause permanent severe problems, such as paralysis or impaired bladder and bowel control ( urinary incontinence and fecal incontinence). (msdmanuals.com)
  • Patients should have failed at least 6 weeks of non-operative treatment or have had the presence of progressive symptoms or signs of nerve root/spinal cord compression in the face of continued non-operative management prior to implantation of the PRESTIGE LP™ Cervical Disc. (medtronic.com)
  • c) Confirmation of nerve root compression on Magnetic Resonance Imaging (MRI) that is related to the clinical findings. (who.int)
  • Myelopathy can be the result of primary intrinsic disorders of the spinal cord or from secondary conditions, which result in extrinsic compression of the spinal cord. (bvsalud.org)
  • Disc degeneration with herniation is a common clinical manifestation of spinal column pathology in young and adult people. (bmj.com)
  • Globus ExcelsiusGPS™ is a sophisticated system that is designed to make spinal fusion safer and help with precise placement of implants and hardware placement. (sanramonmedctr.com)
  • This fusion stabilizes the underlying problem that caused the compression. (upmc.com)
  • Normal voiding is essentially a spinal reflex modulated by the central nervous system (brain and spinal cord), which coordinates function of the bladder and urethra. (medscape.com)
  • The central nervous system is composed of the brain, brain stem, and the spinal cord. (medscape.com)
  • The signal transmitted by the brain is routed through 2 intermediate segments (the brainstem and the sacral spinal cord) prior to reaching the bladder. (medscape.com)
  • A cervical spine computerized tomography (CT) scan consequently performed revealed spondylodiscitis in the C5-C6 intravertebral space, with destructive changes in the C5 vertebral body and presence of tissue in the right lateral paravertebral space. (who.int)
  • Floating Lateral Mass Fractures of the Cervical Spine. (medscape.com)
  • Final diagnosis was therefore Langerhans cell histiocytosis of the dorsal spine complicated by spinal cord compression. (scirp.org)
  • Stimulation produces an action potential that travels up the axon toward the spinal cord and past the cell bodies of the sensory axons of the large-fiber sensory system in the dorsal root ganglia to the ipsilateral posterior columns of the spinal cord. (medscape.com)
  • 60% maximum pulling force) task for 12 weeks on motor behavior and nerve function, inflammatory responses in forearm musculoskeletal and nerve tissues and serum, and neurochemical immunoexpression in cervical spinal cord dorsal horns. (cdc.gov)
  • Lastly, Substance P and neurokinin-1 were both increased in weeks 6 and 12 in the dorsal horns of cervical spinal cord segments. (cdc.gov)
  • The peripheral inflammatory responses were associated with signs of central sensitization (mechanical allodynia and increased neurochemicals in spinal cord dorsal horns). (cdc.gov)
  • Although ENBs often recur and have an aggressive clinical course, spinal metastases are extremely rare and the underlying molecular mechanisms are poorly understood. (thejns.org)
  • Twenty spinal metastases from renal origin (17 patients) treated by preoperative embolization with polyvinyl alcohol particles were analyzed retrospectively. (ajnr.org)
  • Preoperative embolization of spinal metastases of renal origin with polyvinyl alcohol particles is safe and might reduce intraoperative blood loss significantly. (ajnr.org)
  • There is, however, limited data about the effect of preoperative embolization on intraoperative blood loss in spinal metastases of renal origin (6, 7, 15) . (ajnr.org)
  • The control group consisted of 10 consecutive patients with 11 spinal metastases of renal carcinoma, which were treated surgically without preoperative embolization between April 1994 and April 1997. (ajnr.org)
  • Powell also underwent an MRI in November 2007 that revealed multilevel cervical disc herniation with evidence of moderate cord compression. (justia.com)
  • The PRESTIGE LP™ Cervical Disc is implanted using an anterior approach. (medtronic.com)
  • The PRESTIGE LP™ Cervical Disc should only be used by surgeons who are experienced with anterior cervical spinal procedures and have undergone adequate hands-on training in the use of this specific device. (medtronic.com)
  • Only surgeons who are familiar with the implant components, instruments, procedure, clinical applications, biomechanics, adverse events, and risks associated with the PRESTIGE LP™ Cervical Disc should use this device. (medtronic.com)
  • Devices with metal-on-metal articulating surfaces (such as the Prestige LP Cervical Disc) may release wear debris, metallic particles or metal ions locally near the device and/or systemically. (medtronic.com)
  • Patients in the clinical study of the PRESTIGE LP™ Cervical Disc were instructed to use non-steroidal anti-inflammatory drugs (NSAIDs) for two weeks postoperatively. (medtronic.com)
  • moreover, no genetic linkage between spinal disc herniation and spastic paraplegia has ever been described. (bmj.com)
  • As far as upper spinal disc herniations and related paraplegia are concerned, similar genetic studies have not yet been reported, in spite of considerable information collected about hereditary spastic paraplegia (HSP). (bmj.com)
  • Anterior cervical procedures are minimally invasive and have great results for low infection, reduced pain and increased return to function. (parkview.com)
  • Similar to Chiari type I of humans, there is a wide spectrum of possible neurologic presentations for dogs with CM/SM, including cervical myelopathy, cerebellovestibular dysfunction, and forebrain dysfunction (e.g., seizure activity). (vin.com)
  • Cervical spine X-ray showed narrowed C5-C6 and C6-C7 intravertebral spaces and a possible paravertebral anterior mass in the C6-C7 area. (who.int)
  • Multilevel Corpectomy With Anterior Column Reconstruction and Plating for Subaxial Cervical Osteomyelitis. (medscape.com)
  • CT scan of the cervical spine, showing a calcified mass at the transverse ligament at baseline (A) and 2 months later (B). (medscape.com)
  • San Ramon Regional Medical Center offers advanced treatments to help patients find lasting relief from conditions ranging from lower back pain to spinal stenosis. (sanramonmedctr.com)
  • This is the case of a 39-year-old male presenting with cervical myelopathy caused by a compressive sarcoid nodule who underwent a successful posterior decompressive procedure. (surgicalneurologyint.com)