Squamous cell carcSubtypesLymph node metastasisColorectal cancerGastric cancersMetastasisCarcinomasEndometrialPapillaryLeiomyosarcomaClinicalCardiaLungPrognosisUterineOvarian cancerGlandularLesionsPathologyMalignanciesRegistryMethodsMalignant tumorsBladder cancerMortalitiesInvolvementBiomarkersPreoperativeProvenTypesIncidencePatientsUterusDysplasiaProgressionSynchronousTobacco2016DiagnosisRareIncludeCommonTherapeuticDataGroupsDisease
Squamous cell carc3
- Analysis of TCGA pan-cancer data revealed significant overexpression of CASC9 across different other entities including bladder, liver, lung and stomach cancers and especially in squamous cell carcinoma (SCC) of the lung. (biomedcentral.com)
- We retrospectively analyzed the clinical data of 16 patients who underwent resection of synchronous advanced esophageal squamous cell carcinoma (ESCC) and gastric adenocarcinoma from January 2009 to Dec 2021. (biomedcentral.com)
- In this study, we retrospectively analyzed the clinical data of 16 patients who received synchronous resection of advanced esophageal squamous cell carcinoma (ESCC) and gastric adenocarcinoma at our institution, and evaluated the feasibility and efficacy of this treatment modality and analyzed the impacts of different clinical parameters on the overall survival. (biomedcentral.com)
Subtypes1
- Some are of different histological subtypes (including the category extremely rare occurrences (and will normally have been `flagged' `uncertain histology') within the total of morphologically verified as such by some verification procedure within the registry or at cases for the particular ICD category. (who.int)
Lymph node metastasis1
- Cox regression analysis indicated that lymph node metastasis of both cancers was independent risk factor for overall survival. (biomedcentral.com)
Colorectal cancer2
- It is the fourth most common cancer, accounting for 7% of female cancers, following breast, lung, and colorectal cancer. (medscape.com)
- Another group of women at increased risk of premenopausal endometrial cancer are those with Lynch II syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC). (medscape.com)
Gastric cancers1
- The aim of this study was to evaluate the feasibility and efficacy of simultaneous resection of synchronous advanced esophageal and gastric cancers. (biomedcentral.com)
Metastasis2
- Metastasis from endometrial cancer to small bowel is very rare [ 3 ]. (karger.com)
- In this report, we highlight an unusual site of metastasis of an endometrial adenocarcinoma to the small intestine. (karger.com)
Carcinomas4
- It proved to be a valid biomarker especially in detecting squamous intraepithelial lesions in cervical liquid-based samples and in discerning these lesions from their mimickers, as well as in ovarian, endometrial, vulvar, primary and metastatic melanomas, breast, pancreatic and renal cell carcinomas. (medsci.org)
- Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)
- Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)
- Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
Endometrial12
- Ovarian cancer, uterine cervical cancer, endometrial cancer, and trophoblastic neoplasms are gynecologic malignancies for which tumor markers are in clinical use. (medscape.com)
- No tumor markers with high sensitivity and high specificity for endometrial cancer are known at present, although CA-125 is often used in clinical practice. (medscape.com)
- Endometrial cancer is the fourth most common cancer in females and is the most prevalent gynecological malignancy. (karger.com)
- Endometrial adenocarcinoma is the most common gynecologic malignancy in the United States. (medscape.com)
- No evidence suggests that routine endometrial sampling or transvaginal sonography to evaluate the endometrial stripe in asymptomatic women has a role in early detection of uterine cancer, even in women who take tamoxifen after breast cancer or has a cancer syndrome. (medscape.com)
- This article discusses endometrial cancer and uterine sarcomas. (medscape.com)
- While endometrial cancer affects reproductive age as well as postmenopausal women, 75% of endometrial cancers occur in postmenopausal women, with the mean age of diagnosis at 61 years. (medscape.com)
- 4] The most common low-grade endometrioid endometrial cancers have been associated with obesity, nulliparity, anovulatory menstrual cycles, diabetes, and hypertension. (medscape.com)
- This is an autosomally dominant germline mutation in DNA mismatch repair (MMR) genes (MSH1, MSH2, MSH6) and accounts for 9% of patients younger than 50 years with endometrial cancer. (medscape.com)
- These mutations lead to microsatellite instability in 90% of colon cancers and 75% of endometrial cancers. (medscape.com)
- Besides colon cancer, women affected have a 40-60% risk of endometrial cancer by age 70 years, compared to a baseline population risk of 1.5% at the same age. (medscape.com)
- Fifty-one percent of women had endometrial or ovarian cancer diagnosed first as the sentinel cancer. (medscape.com)
Papillary1
- 1. Adenocarcinoma: papillary, mucoid, trabecular (well-differentiated). (poznayka.org)
Leiomyosarcoma1
- Oesophageal cancer is group comprising several histological types, chiefly squamous cell (SCC), adenocarcinoma, leiomyosarcoma and other rarer types. (omicsonline.org)
Clinical3
- SCC antigen is useful in the clinical management of advanced cervical cancer. (medscape.com)
- Here we explore the epidemiology, aetiology and clinical aspects of this group of cancers. (omicsonline.org)
- Thus, surgeons may face the dilemma of patients presenting with simultaneous gastric and esophageal cancers in clinical settings, but there are no established treatment guidelines for these patients. (biomedcentral.com)
Cardia1
- The involvement may be localized to pyloric antrum, or diffuse affecting whole of the stomach from the cardia to pylorus. (poznayka.org)
Lung2
- [ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)
- [ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)
Prognosis3
- However, it has a favorable prognosis because the majority of patients present at an early stage, resulting in only 4% of cancer deaths in women. (medscape.com)
- 9% of cancers of uterine corpus, however is associated with more aggressive behavior and a poorer prognosis. (medscape.com)
- Background: Vestigial like family member 3 (VGLL3) is associated with the prognosis of epithelial ovarian cancer and soft tissue sarcoma, but its role in gastric cancer (GC) is unclear. (researchgate.net)
Uterine4
- Uterine cancer is defined as any invasive neoplasm of the uterine corpus. (medscape.com)
- The most common of these malignancies is uterine cancer. (medscape.com)
- Cancer of the uterine corpus is the most common pelvic gynecologic malignancy in the United States and in most developed countries with access to sufficient health care. (medscape.com)
- After doubling in the early 1970s, the incidence of uterine cancer has remained fairly constant. (medscape.com)
Ovarian cancer1
- Because pathologic diagnosis of ovarian cancer is difficult without laparotomy, tumor markers such as CA-125, in addition to diagnostic imaging, are useful in preoperative evaluation for ovarian cancer. (medscape.com)
Glandular2
- Microscopically, early gastric carcinoma is a typical glandular adenocarcinoma, usually well-differentiated. (poznayka.org)
- A few notes on each cancer site and its subgroups staining techniques (e.g., glandular and diffuse neoplasms of are included in this chapter. (who.int)
Lesions1
- Majority of ulcer-cancers are malignant lesions from the beginning. (poznayka.org)
Pathology1
- Corresponding author: Dr. Maria Gabriella Malzone, Pathology and Cytopathology Unit, National Cancer Institute "Fondazione G. Pascale", via Mariano Semmola, 80131 Napoli, Italy. (medsci.org)
Malignancies1
- The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
Registry2
- reported that about 5.3% of patients with esophageal cancer had synchronous gastric cancer [ 5 ], and the nationwide registry of Japan reported that about 4.3% of patients with esophageal cancer had synchronous gastric cancer [ 6 ]. (biomedcentral.com)
- We sought to address this issue through the Surveillance, Epidemiology, and End Results (SEER) database, a large population-based cancer registry. (biomedcentral.com)
Methods1
- Overall survival (OS) and cancer-specific survival (CSS) of patients who had SRC were compared with those of patients who had non-SRC using Cox regression and propensity score methods. (biomedcentral.com)
Malignant tumors1
- Adenoid cystic carcinoma, adenocarcinoma and expleomorphic adenoma were observed as primary malignant tumors. (selcukmedj.org)
Bladder cancer1
- Two independent HNSCC tissue sets and a bladder cancer tissue set were analyzed by RT-qPCR. (biomedcentral.com)
Mortalities1
- Moreover, these two cancers are responsible for about half of all cancer mortalities worldwide [ 2 ]. (biomedcentral.com)
Involvement1
- In addition, mean levels of CA-15-3 and CA-19-9 were significantly higher in women who required adjuvant therapy, and levels of CA-19-9 were also predictive of deep myometrial invasion, cervical involvement. (medscape.com)
Biomarkers2
- Long non-coding RNAs (lncRNAs) have shown promise as biomarkers in other cancer types and in some cases functionally contribute to tumor development and progression. (biomedcentral.com)
- Long non-coding RNAs (lncRNAs) have moved into the focus of cancer research as good candidates for tumor biomarkers and as regulators of various neoplastic cell properties. (biomedcentral.com)
Preoperative1
- Synchronous gastric cancer was defined as detection of gastric cancer before surgery based on preoperative esophagogastroduodenoscopy(EGD) that was pathologically proven as adenocarcinoma.Any patient who received simultaneous endoscopic resection for esophageal or gastric cancer was excluded. (biomedcentral.com)
Proven1
- Whereas pleural mesothelioma is highly associated with asbestos exposure , nonmesotheliomatous cancers have generally not been proven to result from exposure to airborne asbestos. (medscape.com)
Types3
- Dysregulation of lncRNA expression has been reported for different cancer types and may contribute to tumor development and progression [ 2 , 3 ]. (biomedcentral.com)
- Tumor markers are soluble glycoproteins that are found in the blood, urine, or tissues of patients with certain types of cancer. (medscape.com)
- Diseases for Oncology (ICD-O-2)) that were used for tabulation of Diagnostic subgroups are presented for 15 cancers, as defined by the major types of sarcoma, and for mesotheliomas. (who.int)
Incidence3
- The incidence of gastro-oesophageal cancer has striking geographical variation as does the gold standard treatment. (omicsonline.org)
- While incidence is increasing overall 5-year survival remains poor making this relatively rare cancer the 6th leading cause of cancer related death world-wide [ 1 - 3 ]. (omicsonline.org)
- Oesophageal adenocarcinoma is also associated with tobacco use, with a higher incidence in men [ 7 ]. (omicsonline.org)
Patients6
- Tumor markers are not elevated in all cancer patients, particularly patients with early-stage cancer. (medscape.com)
- From January 2009 to December 2021, patients who had primary ESCC and gastric adenocarcinoma and received simultaneous radical surgical resection at the Department of Cardiothoracic Surgery in Huashan Hospital were retrospectively enrolled. (biomedcentral.com)
- Patients with early tumors located in the upper gastric cancer and adenocarcinoma infiltrating the dentate line were also excluded. (biomedcentral.com)
- Patients with adenocarcinoma of the gallbladder were identified in the Surveillance, Epidemiology, and End Results database from 1973 to 2016. (biomedcentral.com)
- At the end of the follow-up period, 3050 patients (13.4%) were alive, 13,890 patients (61.0%) died from cancer, and 5841 (25.6%) patients died of other causes. (biomedcentral.com)
- Targeted tailored management of the breast cancer patient at risk for harboring a germline mutation-current trends affecting the selection of patients considering surgical prophylaxis for breast cancer. (nebraska.edu)
Uterus1
- Currently, no screening tests for cancer of the uterus are recommended for asymptomatic women. (medscape.com)
Dysplasia2
- carcinoma in situ in the stomach (a state of severe cellular atypia or dysplasia, without invasion across the basement membrane of the glands). (poznayka.org)
- The protective changes in the lower oesophagus brought about by persistent acid exposure can result in dysplasia, with a 0.5% risk of development of adenocarcinoma per year [ 13 ]. (omicsonline.org)
Progression4
- Cancers will recur in 30-80% of cases, with a progression to muscle invasive disease of 1-45% within 5 year [ 2 , 3 ]. (medsci.org)
- LPA receptors and autotaxin (ATX), a secreted phosphodiesterase that produces this phospholipid, are overexpressed in many cancers and impact several features of the disease, including cancer-related inflammation, development, and progression. (hindawi.com)
- In this review, we discuss the evidence linking LPA signaling to cancer-related inflammation and its impact on cancer progression. (hindawi.com)
- Recent evidences demonstrate that dysregulated expression of microRNA-320d (miR-320d) has been associated with several cancer development and progression. (biomedcentral.com)
Synchronous1
- The existence of synchronous tumors of the esophagus and stomach is not unusual, the radical surgical treatment could be carried out whenever possible. (biomedcentral.com)
Tobacco1
- Many of the risk factors are shared in these two cancers, especially the use of alcohol and tobacco, and poor social and economic status. (biomedcentral.com)
20161
- The adenocarcinoma of the gallbladder part in the SEER database diagnosed from 1973 to 2016 was the source of present analysis. (biomedcentral.com)
Diagnosis2
- The diagnosis of this condition has been made possible by extensive work on histogenesis of gastric cancer by Japanese pathologists by the use of fiberoptic endoscope and gastrocamera. (poznayka.org)
- Gastro-oesophageal cancer remains a devastating diagnosis for the patient and a challenge for the clinician. (omicsonline.org)
Rare1
- Signet ring cell carcinoma (SRC) is a rare histological subtype of gallbladder adenocarcinoma. (biomedcentral.com)
Include1
- Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
Common1
- A recent review of cancer statistics in China reported that gastric cancer was the second most common cancer and esophageal cancer was the sixth most common [ 1 ]. (biomedcentral.com)
Therapeutic1
- Many ongoing studies aim to understand ATX-LPA axis signaling in cancer and its potential as a therapeutic target. (hindawi.com)
Data1
- Data table showing topics related to specific cancers and associated disorders. (cancerindex.org)
Groups3
- In contrast to adenocarcinoma, SCC appears to be commoner in lower socioeconomic groups [ 10 ]. (omicsonline.org)
- IARC Technical Report Histological Groups for Comparative available at IARC. (who.int)
- Signet ring cell carcinoma (SRC) is an adenocarcinoma in which more than 50% of the tumor consists of isolated or small groups of malignant cells containing intracytoplasmic mucins [ 1 ]. (biomedcentral.com)
Disease1
- In the case of adenocarcinoma, this may be accompanied by symptoms relating to reflux disease. (omicsonline.org)