• The results of numerous studies demonstrate that diazoxide limits infarct size after middle cerebral artery or unilateral carotid artery occlusion in rodents, preserves cerebrovascular function in newborn piglets, and reduces the activation of microglia after permanent, bilateral common carotid artery occlusion in rats. (elsevier.com)
  • The study of variations in genes involved in the different events that trigger the atherogenic process, such as lipid metabolism (modification of LDL-cholesterol), endothelial function and hypertension, immune response (recruitment of macrophages and foam cell formation) and stability of atherosclerotic plaques (thrombosis), established the risk for suffering a vascular disorder. (cdc.gov)
  • Cerebrovascular disorders include a wide variety of conditions that affect the blood vessels and circulation in the brain. (muhealth.org)
  • Similarly, cerebrovascular disorders affect the blood vessels and arteries that supply the brain, but come in many forms. (guthrie.org)
  • The neurologists and neurosurgeons at Scripps care for the entire spectrum of cerebrovascular disorders, which involve the veins and arteries within the brain and neck. (scripps.org)
  • The defining syndromes of bipolar disorder, mania and hypomania, can occur following stroke, including in individuals who are seemingly otherwise not at risk based on age, family history, and past psychiatric history. (springer.com)
  • Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies with Major Depressive Disorder (MDD) and other psychiatric disorders. (nih.gov)
  • Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. (nih.gov)
  • An association between cerebrovascular events and psychiatric disorders has been reported. (bioportfolio.com)
  • In recent years, polyphenols have gained considerable attention owing to their potential in preserving cognitive function and preventing neurodegenerative disorders [ 8 , 10 , 11 , 12 , 13 ]. (mdpi.com)
  • Glial biology has come into its own recently, as researchers have shown that glia are critical for the development of the nervous system and have key roles in various neurodegenerative disorders" (Aamodt 2007). (scienceblogs.com)
  • Deficient sleep duration and sleep disturbances - such as insomnia, sleep disordered breathing (SDB) and restless legs syndrome (RLS)- are associated with hypertension and cardio-cerebrova. (bioportfolio.com)
  • These mechanisms include-though are not limited to-inflammation, oxidative stress/mitochondrial dysfunction, abnormalities in the hypothalamic-pituitary-adrenal axis, and sleep disorders. (springer.com)
  • This elevation in risk is large and estimated to be approximately twice that expected from general population estimates for both cerebrovascular mortality and events. (springer.com)
  • Osby U, Brandt L, Correia N, Ekbom A, Sparen P. Excess mortality in bipolar and unipolar disorder in Sweden. (springer.com)
  • Excess cardiovascular and suicide mortality of affective disorders may be reduced by lithium prophylaxis. (springer.com)