• He is mostly known for his discovery of encephalitis lethargica and his atlas of cytoarchitectonics of the cerebral cortex. (wikipedia.org)
  • In contrast, caffeine at doses reflecting daily human consumption does not induce a release of dopamine in the shell of the nucleus accumbens but leads to a release of dopamine in the prefrontal cortex, which is consistent with its reinforcing properties. (medscape.com)
  • In AD, plaques develop in the hippocampus, a structure deep in the brain that helps to encode memories, and in other areas of the cerebral cortex that are involved in thinking and making decisions. (medscape.com)
  • For example, within the cerebellum, a structural separation emerges between lobules that are functionally connected to distinct, mainly sensorimotor, cognitive and limbic regions of the cerebral cortex and subcortex. (nih.gov)
  • Cerebral Cortex , 33 (11), 6891-6901. (upenn.edu)
  • Many studies have examined motor impairments using voxel-based lesion symptom mapping (VLSM), but few are reported regarding the corresponding relationship between cerebral cortex injury and lower limb motor impairment analyzed using this technique. (news-medical.net)
  • The human cerebral cortex is generally considered the most complex organ, and is the structure that we hold responsible for the repertoire of behavior that distinguishes us from our closest living and extinct relatives. (biologists.com)
  • held in September 2013, researchers considered new information from the fields of developmental biology, genetics, genomics, molecular biology and ethology to understand unique features of the human cerebral cortex and their developmental and evolutionary origin. (biologists.com)
  • In 1664, Thomas Willis proposed that higher cognitive functions originate from the convolutions of the cerebral cortex and not from the fluid or other structures in the brain or other parts of the body ( Molnár, 2004 ). (biologists.com)
  • The cerebral cortex constitutes half the volume of the human brain and is presumed to be responsible for the neuronal computations underlying complex phenomena such as perception, thought, language, attention, episodic memory and voluntary movement. (biologists.com)
  • Is the human cerebral cortex unique? (biologists.com)
  • By isolating and analyzing the nuclei of individual human brain cells, researchers identified 16 neuronal subtypes in the cerebral cortex-the brain's outer layer of neural tissue responsible for cognitive functions including memory, attention and decision making. (neurodegenerationresearch.eu)
  • To better understand this diversity, researchers analyzed more than 3,200 single human neurons in six Brodmann areas, which are regions of the cerebral cortex classified by their functions and arrangements of neurons. (neurodegenerationresearch.eu)
  • The ascending pathway transmits impulses from the spiral organ (of Corti) to the cerebral cortex (see the following image). (medscape.com)
  • Previous studies of global brain hypoxia ischemia have primarily focused on injury to the cerebral cortex and to the hippocampus. (cdc.gov)
  • In summary, our results demonstrate that the relationship between structural and functional connectivity is fine-grained, widespread across the entire brain, and driven by covariation in cortical area, i.e. likely differences in shape, depth, or number of foldings. (nih.gov)
  • Correlation analyses revealed a cerebral cortical volumetric loss of ∼ 0.11% of the intracranial vault for each daily drink (0.25 g/kg), and selective vulnerability of cortical and non-cortical brain regions. (nature.com)
  • The pattern of volumetric changes observed in nonhuman primates following 15 months of drinking suggests that cerebral cortical gray matter changes are the first macroscopic manifestation of chronic ethanol exposure in the brain. (nature.com)
  • Schizophrenia is characterized by cortical circuit abnormalities, which might be reflected in γ-frequency (30-100 Hz) oscillations in the electroencephalogram. (harvard.edu)
  • By bringing together researchers from diverse backgrounds but with a common interest, and encouraging in-depth discussion between participants, this intimate workshop helped to identify key areas for future work to ultimately improve ourunderstanding of human-specific brain evolution and of diseases related to higher cortical function. (biologists.com)
  • Researchers deciphered what types of genes were "turned on" within each nucleus and revealed that various combinations of the 16 subtypes tended to cluster in cortical layers and Brodmann areas, helping explain why these regions look and function differently. (neurodegenerationresearch.eu)
  • Also, by examining drawing characteristics made by the normal children and handicapped children (intellectually handicapped children, down syndrome children, cerebral palsy), the relationship between the M scale and the intellectual ability or writing motion function of the children was confirmed. (scirp.org)
  • age, 9 +/- 1.5 yrs) and two cerebral palsy (CP) patients (1 male age 10 yrs with apparent equinus, 1 female age 14 yrs with Winters type 4 gait pattern) walking over ground at a preferred speed. (cdc.gov)
  • Cerebral palsy is a neurological condition that often impacts joints, muscles, bones and tendons. (jdch.com)
  • Pediatric orthopedic surgeons at Joe DiMaggio Children's Hospital have extensive knowledge of cerebral palsy complications. (jdch.com)
  • We are in clinics throughout South Florida, making it easier to receive cerebral palsy evaluations and treatment close to home. (jdch.com)
  • Addressing orthopedic conditions of cerebral palsy with surgery requires expert care from an experienced team. (jdch.com)
  • Our cerebral palsy surgery options include procedures that are not widely available. (jdch.com)
  • Nationally renowned pediatric specialists in hip, spine and other specialties deliver services reflecting the latest science in orthopedic cerebral palsy care. (jdch.com)
  • All providers specialize in pediatrics and have deep experience in cerebral palsy. (jdch.com)
  • Conservative approach: Your child has more treatment options when you come to an orthopedic program specializing in cerebral palsy such as ours. (jdch.com)
  • Before recommending cerebral palsy surgery, we first consider nonsurgical therapies offering the greatest benefit. (jdch.com)
  • In pediatric rehabilitation, cerebral palsy constitutes one of the most diagnosed clinical conditions, however, further research is still necessary to improve care quality in the Brazilian context. (bvsalud.org)
  • Pediatric rehabilitation and cerebral palsy más diagnosticadas, pero se requiere pesquisas para mejorar la calidad asistencial brasileña. (bvsalud.org)
  • Cerebral blood flow (CBF) is an indirect marker of neuronal function. (frontiersin.org)
  • In the mammalian cerebral neocortex, different regions have different cytoarchitecture, neuronal birthdates, and functions. (elsevierpure.com)
  • Researchers can use these different neuronal subtypes to build a "reference map" of the human brain-a foundation to understand the differences between a healthy brain and a diseased brain. (neurodegenerationresearch.eu)
  • In this review, the role of cerebrovascular reactivity to L-arginine (CVR-L-Arg) for assessment of cerebral endothelial function is discussed. (hindawi.com)
  • CVR-L-Arg has been compared to flow-mediated dilatation as a gold standard for systemic endothelial function and intima-media thickness as a marker for morphological changes. (hindawi.com)
  • However, it seems to show specific cerebral endothelial function. (hindawi.com)
  • So far CVR-L-Arg has been used to study cerebral endothelial function in many pathological conditions such as stroke, migraine, etc. (hindawi.com)
  • In conclusion CVR-L-Arg is a promising noninvasive research method that could provide means for evaluation of cerebral endothelial function in physiological and pathological conditions. (hindawi.com)
  • Endothelial function is not uniform throughout the arterial system. (hindawi.com)
  • Until recently it was impossible to determine specific cerebral endothelial function. (hindawi.com)
  • However, these techniques do not enable any evaluation of cerebral endothelial function. (hindawi.com)
  • In the past few years cerebrovascular reactivity to L-arginine by means of TCD has emerged as a parameter for evaluation of cerebral endothelial function [ 3 - 7 ]. (hindawi.com)
  • Recently, we analyzed serum biomarkers by using samples from the Gulu outbreak and identified associations between cytokines/chemokines, acute-phase reactants, makers of coagulopathy, and markers of endothelial function and patient death, hemorrhage, and viremia ( 10 ). (cdc.gov)
  • Blood flow is indeed directly related to the cerebral metabolic rate of glucose consumption (CMR glc ) ( Sokoloff, 1978 ). (frontiersin.org)
  • The origin of the latter problem is not due to our current inability to estimate accurately cerebral metabolic rate of oxygen (CMRO2) from the BOLD signal, but to the fact that haemodynamic responses are sensitive to the size of the activated population, which may change as the sparsity of neural representations varies spatially and temporally. (freethoughtblogs.com)
  • Classic drugs of abuse lead to specific increases in cerebral functional activity and dopamine release in the shell of the nucleus accumbens (the key neural structure for reward, motivation, and addiction). (medscape.com)
  • Moreover, this dose is 5-10 times higher than the dose necessary to stimulate the caudate nucleus (extrapyramidal motor system) and the neural structures regulating the sleep-wake cycle, the 2 functions that are most sensitive to caffeine. (medscape.com)
  • This represents the first study to show that women remitted from AN have aberrant resting neurovascular function in homeostatic neural circuitry in response to hunger. (frontiersin.org)
  • Alpha and beta neural oscillations differentially reflect age-related differences in bilateral coordination. (mpg.de)
  • These findings suggest that the basic E/I imbalance model should be updated to higher-dimensional models that can better capture the multidimensional computational functions of neural circuits. (biorxiv.org)
  • Background: In chronic schizophrenia and chronic bipolar disorder, gamma band (30-100 Hz) auditory steady-state EEG responses (ASSRs) are reduced in power and phase locking, likely reflecting neural circuit dysfunction. (harvard.edu)
  • Background: Oscillatory electroencephalogram (EEG) abnormalities may reflect neural circuit dysfunction in neuropsychiatric disorders. (harvard.edu)
  • Next, speakers considered how changes to developmental processes might underlie these anatomical differences, with a focus on neural stem and progenitor populations, human-specific developmental processes, and the search for genomic events that may underlie the developmental and morphological differences that distinguish modern humans. (biologists.com)
  • In addition, imaging of the cerebral function became possible by functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) scan. (hindawi.com)
  • Ultrasound remains the ultimate method for real time functional cerebral blood flow imaging. (hindawi.com)
  • Methods: Fifteen individuals with gambling disorder and 17 matched healthy controls were studied with resting-state functional connectivity MRI and three brain positron emission tomography scans, investigating dopamine (18F-FDOPA), opioid (11C-carfentanil) and serotonin (11C-MADAM) function. (bvsalud.org)
  • The current paper reviews functional magnetic resonance imaging studies investigating age-related differences in emotional processing and discusses how this evidence relates to two opposing theoretical accounts of older adults' positivity effect. (researchgate.net)
  • Long-range coherences in spontaneous brain activity reflect functional connectivity. (nature.com)
  • Here we propose a novel, highly resolved connectivity mapping approach, using ultrafast functional ultrasound (fUS), which enables imaging of cerebral microvascular haemodynamics deep in the anaesthetized rodent brain, through a large thinned-skull cranial window, with pixel dimensions of 100 μm × 100 μm in-plane. (nature.com)
  • For some time, electroencephalography (EEG) has been employed clinically as a measure of brain function in the hope of determining and differentiating certain functional conditions of the brain. (medscape.com)
  • Have the rest of the cognitive functions preserved? (whiteblog.net)
  • The clinical high risk (CHR) period is a phase denoting a risk for overt psychosis during which subacute symptoms often appear, and cognitive functions may deteriorate. (harvard.edu)
  • Objective: Schizophrenia impairs many cognitive functions, including face perception. (harvard.edu)
  • For the first time, this study demonstrated that indices of RT variability, in particular those derived from the ex-Gaussian function, may complement speed and accuracy parameters in the assessment of executive function impairments in fibromyalgia. (hindawi.com)
  • Much CCA variability is independent of cerebral volume. (ajnr.org)
  • Coffman et al ( 25 ) and Rauch and Jinkins ( 26 ) have both reported significant variability in midsagittal measurements of cerebral structures (including the corpus callosum) that are dependent on subject orientation within the magnet. (ajnr.org)
  • Variability in brain structure and function reflects lack of peer support. (mpg.de)
  • Although there is basic structural similarity across the entire neocortex, different functions are clearly localized in a large number of distinct fields, characterized by their input and output connectivity, their cytoarchitecture, the proportions of cell types, their modular structure and their microcircuitry. (biologists.com)
  • No statistically significant differences were found between viral loads in adults and pediatric patients. (cdc.gov)
  • however, in the pediatric population, this difference did not reach statistical significance, likely because of the small sample size and the wide range of observed values in the pediatric patients with nonfatal cases. (cdc.gov)
  • While the greater decline in hit rate after the change in task rule indicates deficient cognitive flexibility, the lack of any difference in false alarm rate suggests intact response inhibition. (hindawi.com)
  • Individual differences in control of language interference in late bilinguals are mainly related to general executive abilities. (crossref.org)
  • Background: We examined whether individual differences in hemispheric utilization can interact with the intrinsic attentional biases of the cerebral hemispheres. (harvard.edu)
  • Although the bones of the scull remain an obstacle for ultrasound waves and therefore ultrasound may not seem to be the optimal technique for cerebral vessel imaging, transcranial ultrasound techniques were improved and found their place and indications. (hindawi.com)
  • Researchers also looked at brain scans for signs of cerebral small vessel disease, which are signs of vascular brain damage often seen in patients who have dementia. (scienceblog.com)
  • Ischaemic reperfusion injury (IRI) after tourniquet release during total knee arthroplasty (TKR) is related to postoperative cerebral complications. (medsci.org)
  • As a result, transient hypotension and acidosis can occur [ 4 , 5 ], and serious cerebral complications can be induced [ 3 , 6 , 7 ]. (medsci.org)
  • Shedding light on the role of astrocytes in brain metabolism, the earlier picture of astrocytes being restricted to a scaffold-associated function in the brain is now out of date. (frontiersin.org)
  • With the development and optimization of non-invasive techniques, such as nuclear magnetic resonance spectroscopy (MRS), several groups have worked on assessing cerebral metabolism in vivo . (frontiersin.org)
  • Here, we review state-of-the-art MR methods to study brain function and metabolism in vivo , and their contribution to the current understanding of how astrocytic energy metabolism supports glutamatergic activity and cerebral function. (frontiersin.org)
  • In healthy adults, fasting increases CBF, reflecting increased delivery of oxygen and glucose to support brain metabolism. (frontiersin.org)
  • Regions involved in homeostatic regulation showed group differences in the Hungry − Fed contrast, suggesting altered cellular energy metabolism in this circuitry that may reduce motivation to eat. (frontiersin.org)
  • Carbon dioxide (CO2), the major product of metabolism, has a strong impact on cerebral blood vessels, a phenomenon known as cerebrovascular reactivity. (uni-luebeck.de)
  • ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow. (jamanetwork.com)
  • However, it is unknown whether the differences found actually reflect greater accuracy, or whether comparable differences would be observed in pathological gait. (cdc.gov)
  • According to many theories, life habits: mild cognitive impairment is associated with pathological situations such as obesity and alcohol abuse due to the toxicity of some substances that would directly affect the proper functioning of the brain. (whiteblog.net)
  • this, in turn, nonspecifically stimulates most brain structures and thus likely reflects the side effects linked to high caffeine ingestion alone. (medscape.com)
  • Thus, although caffeine fulfills some of the criteria for drug dependence and shares with amphetamine and cocaine a certain specificity of action on the cerebral dopaminergic system, it does not act on the dopaminergic structures related to reward, motivation, and addiction. (medscape.com)
  • Integrating brain function and structure in the study of the human attentional networks. (googleapis.com)
  • The study also found that in men, the test scores were associated with poor memory function and markers of brain shrinkage. (scienceblog.com)
  • Significant brain volume shrinkage occurred in the cerebral cortices of monkeys drinking ⩾ 3 g/kg ethanol/day (12 alcoholic drinks) at 6 months, and this persisted throughout the period of continuous access to ethanol. (nature.com)
  • Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. (frontiersin.org)
  • Cerebral function requires the cooperative interaction between different cell types, namely neurons, astrocytes, microglia and oligodendrocytes, and depends on high metabolic activity supported by continuous supply of oxygen and glucose from the blood ( Siesjö, 1978 ). (frontiersin.org)
  • Endothelium forms the inner cellular lining of blood vessels and plays an important role in many physiological functions including the control of vasomotor tone. (hindawi.com)
  • Transcranial Doppler sonography is used for evaluation of cerebral blood flow changes. (hindawi.com)
  • Endothelial cells are highly metabolically active and play an important role in many physiological functions, including the control of vasomotor tone, blood cell trafficking, haemostatic balance, permeability, proliferation, and immunity. (hindawi.com)
  • Cerebral endothelium is probably one of the most specific types since it is the crucial element of the well-known blood-brain barrier. (hindawi.com)
  • In the past few decades the immense development of neuroradiological methods enabled better imaging of cerebral blood vessels. (hindawi.com)
  • TCD enables continuous monitoring of mean blood flow velocity through the cerebral arteries and therefore the evaluation of cerebral blood flow [ 2 ]. (hindawi.com)
  • Cerebral autoregulation maintains constant blood flow (CBF) through the brain in spite of changing mean arterial pressure [ 8 ]. (hindawi.com)
  • Autoregulation of cerebral blood flow consists of mechano- and chemoregulation. (hindawi.com)
  • Cardiovascular risk factors: the presence of diabetes, arterial hypertension, and its consequences at the level of the cerebral blood vessels are essential for the development of this pathology. (whiteblog.net)
  • Methods We measured sH2a levels in serum using a monoclonal antibody and an ELISA assay that we developed, comparing with routine liver function markers. (centralparkcarriagesofficial.org)
  • Researchers have identified structural brain differences that could help to distinguish patients with unipolar and bipolar depression. (news-medical.net)
  • Cardiac Auscultation Auscultation of the heart requires excellent hearing and the ability to distinguish subtle differences in pitch and timing. (msdmanuals.com)
  • Cerebral endothelial dysfunction is mentioned in the pathophysiology of several neurological diseases. (hindawi.com)
  • It is known that aging per se leads to a progressive loss or dysfunction of neurological functions, visual, auditory, language, and memory, especially for recent events (episodic memory), not for long-term memory, which stores practically unlimited. (whiteblog.net)
  • Alzheimer disease (AD) is a neurodegenerative disorder marked by cognitive and behavioral impairment that significantly interferes with social and occupational functioning. (medscape.com)
  • After many years of research in this regard, mild cognitive impairment is defined as the intermediate state between a normal mental situation and dementia, emphasizing memory impairment as the primary function affected. (whiteblog.net)
  • The non-amnesic focal form (individual involvement of a function such as a language, without memory impairment). (whiteblog.net)
  • Sociodemographic factors: although it is not universally accepted, numerous scientific works reflect a higher incidence of cognitive impairment in people with a lower educational and social level, either because their mental reserve is lower or because their health care for years has been worse and, therefore, less protective against external factors harmful to the cognitive state. (whiteblog.net)
  • PDF) Age Differences in Brain Activity during Emotion Processing: Reflections of Age-Related Decline or Increased Emotion Regulation? (researchgate.net)
  • The term executive functions refer to complex cognitive abilities that enable the regulation, coordination, and sequencing of basic mental operations [ 11 , 12 ]. (hindawi.com)
  • Researchers found no differences between the participants in Studies 1 and 2. (bvsalud.org)
  • MR imaging enables the in vivo study of cerebral structure and function. (ajnr.org)
  • Fortunately, I can just tell you to go read Christian Jarrett, who explains most of the flaws in the study , or you can look at these graphical illustrations of the magnitude of the differences . (freethoughtblogs.com)
  • Participants in the study took tests of memory and other thinking skills, such as information processing speed, executive function and attention. (scienceblog.com)
  • This study investigated executive functions in fibromyalgia via a Go/No-Go task. (hindawi.com)
  • The present study is concerned with executive functions in FMS. (hindawi.com)
  • However, negative findings have also been reported, including for response inhibition tests [ 18 , 19 ] and by a study quantifying multiple executive functions [ 20 ]. (hindawi.com)
  • [ 1 ] This study revealed no conclusive differences between the young and the elderly. (medscape.com)
  • The new study reflects a growing understanding that individual brain cells are unique: they express different types of genes and perform different functions. (neurodegenerationresearch.eu)
  • However, the research investment into DS also reflects the aspiration that the study of AD in DS will bring benefit to patients with AD whether or not they have DS. (acnr.co.uk)
  • Neurotransmitter systems underlying the identified connectivity differences were investigated using region-of-interest and voxelwise approaches. (bvsalud.org)
  • Our findings provide anatomic evidence of sex differences in interhemispheric connectivity. (ajnr.org)
  • Astrocytic functions modulate neu- served in patients with liver failure and/or ronal ammonia toxicity because ammonia is portal-systemic bypass. (who.int)
  • S100 is an acidic acute liver failure may in part be correlated to protein with a molecular weight of 21 kDA impaired astrocytic functions [16]. (who.int)
  • Finally, we discuss the possible future role of these white matter maps in the assessment of white matter diseases, congenital brain malformations, central nervous system neoplasms (presurgical evaluation), and brain function. (ajronline.org)
  • Optimized assessment may facilitate the personalization of therapies aimed at improving the cognitive function of those with the disorder. (hindawi.com)
  • Assessment of reward-related brain function after a single-dose of oxytocin in autism: A randomized controlled trial. (mpg.de)
  • According to patients' reports, these difficulties can significantly affect social and professional functioning and are among the most serious symptoms of the disorder [ 9 , 10 ]. (hindawi.com)
  • Much of the information about its function has been gained from clinical studies of patients after surgical resection of the callosum for intractable epilepsy ( 1 - 5 ). (ajnr.org)
  • Differential effects of anodal and dual tDCS on sensorimotor functions in chronic hemiparetic stroke patients. (mpg.de)
  • It is used in patients with cognitive dysfunction involving either a general decline of overall brain function or a localized or lateralized deficit. (medscape.com)
  • Results: There was a significant difference in lateral geniculate nuclei volume between the control and advanced glaucoma groups in the right hemisphere ( p = 0.03) and in the left hemisphere between the early and advanced glaucoma patients ( p = 0.026). (mdpi.com)
  • The fMRI signal cannot easily differentiate between function-specific processing and neuromodulation, between bottom-up and top-down signals, and it may potentially confuse excitation and inhibition. (freethoughtblogs.com)
  • The magnitude of the fMRI signal cannot be quantified to reflect accurately differences between brain regions, or between tasks within the same region. (freethoughtblogs.com)
  • Significant differences were found, showing a low presence of the first four variables and a higher presence of the last three. (revistacomunicar.com)
  • There are no significant differences between men and women. (whiteblog.net)
  • Liver function tests, including serum ratio 6/ 5. (who.int)
  • Even at atmospheric CO2 concentrations, impaired cerebrovascular reactivity caused longer apneic episodes and more anxiety, indicating that cerebrovascular reactivity is essential for normal brain function. (uni-luebeck.de)
  • The site-specific reactivity of vessels to CO2 is reflected by regional differences in their gene expression and the release of vasoactive factors from endothelial cells. (uni-luebeck.de)
  • There is increasing evidence for the olfactory system playing a dominant role in dog cognition rather than a more complementary role as is often described in human functioning. (jneurosci.org)
  • Reviewing over 20 years of neuroscience research into sex differences in brain structure, a Cambridge University team has conducted the first meta-analysis of the evidence, published this week in the prestigious journal Neuroscience and Biobehavioral Reviews. (news-medical.net)
  • Prof. McMurray comments, "The concern about increased cerebral amyloid β deposition with sacubitril/valsartan was always hypothetical and multiple enzymatic and other amyloid β clearance pathways exist in the brain that would likely compensate for any decreased clearance related to neprilysin inhibition. (escardio.org)
  • Discrepancies between studies may be explained by differences in the tasks used, as well as in sample size and composition (see [ 15 ] for an overview of the findings of previous studies and a discussion of their differences). (hindawi.com)
  • Many scent breeds, such as the bloodhound, have been selectively bred for olfactory tasks such as tracking, an attribute reflected in their ear and head shape, which optimizes odor collection into the nostrils. (jneurosci.org)
  • How did the size, shape and cellular composition change during evolution to perform these unique functions? (biologists.com)
  • Neurons exhibited many differences in their transcriptomic profiles-the patterns of genes that are being actively expressed by these cells-revealing single neurons with shared, as well as unique, characteristics that likely lead to difference in cellular function. (neurodegenerationresearch.eu)
  • This fact shows that the M scale reflects the developmental standard for children in Japan. (scirp.org)
  • SIGNIFICANCE STATEMENT Questions about the relationship between structure and function in the human brain have engaged neuroscientists for centuries in a debate that continues to this day. (nih.gov)
  • Brains that perform successfully really do "light up" differently and work more efficiently, and Mark has investigated just how the structure and function of brains are altered as a result of how their owners use them. (hachettebookgroup.com)
  • Abnormal BBB function several behavioural manifestations, such frequently occurs with brain damage. (who.int)
  • In humans, the reinforcing stimulus functions of caffeine are limited to low or moderate doses, while high doses usually are avoided. (medscape.com)
  • No differences were found for tactile stimulus. (elsevier.es)
  • Changes in motor symptom severity were quantified using the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), executive function using trail making test (TMT) and parkinsonism using Unified Parkinson's Disease Rating Scale (UPDRS). (bvsalud.org)
  • The research lays the groundwork for "mapping" the gene activity in the human brain and could help provide a better understanding of brain functions and disorders, including Alzheimer's, Parkinson's, schizophrenia and depression. (neurodegenerationresearch.eu)
  • The total score reflects a person's potential for developing dementia. (scienceblog.com)
  • Higher scores reflect higher dementia risk, with scores ranging from -2.7 to +12.7. (scienceblog.com)
  • Clinical dementia is a fairly broad-based decline of brain function, and most definitions center on the patient's intellectual decline and memory dysfunction. (medscape.com)
  • The translating brain: Cerebral activation patterns during simultaneous interpreting. (crossref.org)
  • Only remitted subjects were examined to avoid the confounding effects of malnutrition on brain function. (frontiersin.org)
  • In addition to physical and emotional symptoms, FMS is frequently associated with cognitive disruption, reflected in problems with attention and memory or reduced processing speed, for example [ 6 - 8 ]. (hindawi.com)
  • semester time - and so I didn't have time to comment on this recent PNAS paper that reports on dramatic sex differences in the brains of men and women. (freethoughtblogs.com)
  • However, propofol is thought to produce its sedative/anesthetic effects by the positive modulation of the inhibitory function of the neurotransmitter GABA through the ligand-gated GABA A receptors. (guidelinecentral.com)
  • Processing demands upon cognitive, linguistic, and articulatory functions promote grey matter plasticity in the adult multilingual brain: Insights from simultaneous interpreters. (crossref.org)
  • Investigating adult age differences in real-life empathy, prosociality, and well-being using experience sampling. (mpg.de)
  • Only a small linear relationship of CCA with cerebral volume was noted ( r 2 = 0.15), and CCA was not significantly correlated with age or handedness. (ajnr.org)
  • Genetic factors: research has been carried out over the years that have revealed the relationship with a series of proteins and genes whose function is altered in this pathology. (whiteblog.net)