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  • brains
  • In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium . (wikipedia.org)
  • For species of mammals, larger brains (in absolute terms, not just in relation to body size) tend to have thicker cortices. (wikipedia.org)
  • We immunocytochemically identified microglia in fronto-insular (FI) and visual cortex (VC) in autopsy brains of well-phenotyped subjects with autism and matched controls, and stereologically quantified the microglial densities. (springer.com)
  • hemispheric
  • When unfolded in the human, each hemispheric cortex has a total surface area of about 0.12 square metres (1.3 sq ft). The folding is inward away from the surface of the brain, and is also present on the medial surface of each hemisphere within the longitudinal fissure . (wikipedia.org)
  • frontal
  • Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection. (springer.com)
  • We examined how this transformation progresses along multiple levels of the hierarchy by comparing neural representations in visual, temporal, parietal, and frontal cortices in monkeys categorizing across three visual domains (shape, motion direction, and color). (pnas.org)
  • vivo
  • Consequently, either depletion of endogenous DISC1 or expression of mutDISC1 impairs neurite outgrowth in vitro and proper development of the cerebral cortex in vivo. (nih.gov)
  • neuronal
  • Sparsification of neuronal activity in the visual cortex at eye-opening," Proceedings of the National Academy of Sciences of the United States of America , vol. 106, no. 35, pp. 15049-15054, 2009. (hindawi.com)
  • anatomy
  • Here, we present an automated method for accurately measuring the thickness of the cerebral cortex across the entire brain and for generating cross-subject statistics in a coordinate system based on cortical anatomy. (pnas.org)
  • Disorders
  • The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer's Disease, Parkinson's, addiction, and cardiovascular dysregulation. (elsevier.com)
  • Accurate and automated methods for measuring the thickness of human cerebral cortex could provide powerful tools for diagnosing and studying a variety of neurodegenerative and psychiatric disorders. (pnas.org)
  • The thickness of the cortex is of great interest in both normal development as well as a wide variety of neurodegenerative and psychiatric disorders. (pnas.org)
  • thickness
  • As a consequence, it has been impractical to obtain accurate thickness estimates for the entire cortex in individual subjects, or group statistics for patient or control populations. (pnas.org)
  • This difficulty arises because the thickness of the cortex is a property that can only be properly measured if the location and orientation of the gray/white and pial surfaces both are known. (pnas.org)
  • The difficulty of properly measuring the thickness of the cortex without explicit representations of both the gray/white and pial surfaces is illustrated in Fig. 1 , which shows coronal and axial slices through a T1-weighted MRI volume. (pnas.org)
  • temporal
  • They then pass the baton to the temporal love (dark green area) and the dorsolateral prefrontal cortex (light green area) that allows short-term memorisation. (sciencephoto.com)
  • regions
  • Furthermore, the highly folded nature of the cortex is problematic for manual techniques, frequently resulting in measurement errors in regions in which the cortical surface is not perpendicular to any of the cardinal axes. (pnas.org)