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  • molecules
  • As children and young adults, our bodies manufacture plenty of ceramide molecules to keep our skin healthy, supple, and strong. (skinstore.com)
  • These ceramides affect the molecules through various mechanisms and ultimately lead to apoptosis (programmed cell death) and heart muscle protein instability. (medindia.net)
  • For example, if this interaction between Unc45 and ceramide is preventing Unc45 from performing its normal maintenance, then screening for small molecules that block that interaction could be an avenue to find therapeutics that help Unc45 maintain its role in optimizing muscle protein function. (medindia.net)
  • waxy
  • A long version of waxy, fat-like ceramide appears critical to helping brain cells called astrocytes stay focused on supporting neurons rather than contributing to their demise. (news-medical.net)
  • cardiovascular events
  • Other groups have found relationships between circulating ceramides and future cardiovascular events. (diabetesjournals.org)
  • Mayo Clinic has launched a new type of blood test that will measures blood concentrations of plasma ceramides to predict adverse cardiovascular events in patients with progressing coronary artery disease (CAD). (medindia.net)
  • Cream
  • We highly suggest First Aid Beauty Ultra Repair Cream that incorporates ceramides with shea butter and colloidal oatmeal to produce an amazing calming, smoothing, hydrating cream that reduce symptoms of eczema, dermatitis, and keratosis pilaris. (skinstore.com)
  • This cream fortifies thin skin and supports natural collagen with skin-replenishing Ceramides and high-performance retinols. (elizabetharden.com)
  • proteins
  • The researchers identified a dozen ceramide-interacting proteins (CIPs) out of which ten of them were tested. (medindia.net)
  • He also wants to identify what he believes are the different sets of proteins long and short ceramide bind to. (news-medical.net)
  • Restore
  • Designed to impart sensory appeal, instant smoothing and regenerative benefits to stressed and mature skin, Orgasol ® Restore brings the original efficacy of ceramides into a multifunctional powder. (arkema.com)
  • This formula steps in to give skin back five essential ceramides to restore firmer-looking, supple-feeling skin. (paulaschoice.com)
  • 2000
  • Kolesnick RN, Goni FM, Alonso A (2000) Compartmentalization of ceramide signaling: physical foundations and biological effects. (springer.com)
  • suggest
  • Over the past 20 years, a large number of studies in preclinical models suggest that ceramides may be among the most pathogenic nutrient metabolites that accumulate in obesity, linking overnutrition to insulin resistance and its sequelae of comorbidities. (diabetesjournals.org)
  • dysfunction
  • Here, we summarize these results in the context of other preclinical and clinical studies investigating roles for ceramides as drivers of cardiometabolic dysfunction. (diabetesjournals.org)
  • 1 ) are interesting to consider in relation to other recent studies evaluating relationships between ceramides and clinical indices of cardiometabolic dysfunction. (diabetesjournals.org)
  • Mask
  • Your skin goes into natural repair mode while you sleep - Ceramide Overnight Firming Mask is formulated to optimally support this process. (elizabetharden.com)
  • Formulated with 30 percent coconut water and ceramides, this sheet mask quickly recharges skin with deep and refreshing hydration, leaving skin dewy and healthy-looking. (jcpenney.com)
  • levels
  • Decreased levels of ceramides occur in atopic skin as compared with age-matched healthy controls. (cosmeticsandtoiletries.com)
  • Normalization of ceramide levels in the lungs of patients with cystic fibrosis may be a promising therapeutic approach. (sciencemag.org)
  • We have used Drosophila as a model to show that elevated levels of ceramide --driven by genetic or dietary manipulation-- is sufficient to induce LCM," says Rolf Bodmer, Ph.D., professor and director of the Development, Aging and Regeneration Program at SBP and senior author of the paper. (medindia.net)
  • According to Bodmer, the reduction and elevation of ceramide levels cause a specific form of lipotoxic cardiomyopathy. (medindia.net)
  • The results of the study were based on various genetic and pharmacological methods that were used to increase and decrease ceramide levels. (medindia.net)