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  • lactamase
  • Guidelines recommend the use of fluoroquinolones, cephalosporins, and β lactam/β lactamase inhibitor combinations as treatment options [ 2 , 3 ]. (kjim.org)
  • Infections
  • Despite the increased 3GC resistance in community-onset infections, an amikacin combination therapy could provide an option for treatment of bacteremic patients with previous antibiotic exposure in an ED. (kjim.org)
  • First-generation and second-generation cephalosporins are inactive against Enterobacter infections. (medscape.com)
  • Third-generation cephalosporins are not indicated for the treatment of severe Enterobacter infections, perhaps with the notable exception of uncomplicated infections. (medscape.com)
  • Intensive Care Antimicrobial Resistance Epidemiology (ICARE) Surveillance Report, data summary from January 1996 through December 1997: A report from the National Nosocomial Infections Surveillance (NNIS) System. (medscape.com)
  • Gonorrhea
  • But the effectiveness of cephalosporins for treating gonorrhea has been decreasing rapidly. (redorbit.com)
  • A change in prescribing recommendations for gonorrhea in England and Wales -- prompted by rising drug resistance -- appears to have been rewarded with success, researchers reported. (medpagetoday.com)
  • species
  • While cephalosporins were found to be efficient inhibitors of penicillin-binding protein 1 (PBP1), -2, and -4 in L. monocytogenes , which are completely blocked at concentrations well below the MIC, the innate resistance to cephalosporins is thought to be due to their lack of affinity for PBP3, the primary lethal target for β-lactams in the species ( 18 , 44 ). (asm.org)
  • ampC
  • Standard Kirby-Bauer disc diffusion (KBDD) methods and automated minimal inhibitory concentration (MIC) instruments used in most clinical laboratories do not readily detect ampC -type of inducible resistance. (biomedcentral.com)
  • multidrug
  • Relatively little is known about the role that multidrug-resistant organisms (MDROs), and specifically ESC-resistance, play in recurrent UTIs. (biomedcentral.com)
  • Resistance to gentamicin, kanamycin and chloramphenicol as well as the frequency of bla(TEM) and IncA/C significantly decreased over the study period, whereas the frequency of IncI1 and multidrug resistance to seven antimicrobial categories significantly increased. (edu.au)
  • significantly increased
  • Community-onset UTI due to EB demonstrating ESC-resistance is associated with a significantly increased hazard of recurrent UTI within 12 months compared to ESC-susceptible EB, even after adjusting for baseline factors that predispose patients to UTI recurrence. (biomedcentral.com)