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  • improves
  • Vitamin D improves gut flora and metabolic syndrome - Science Daily, 12/21/16 - 'a high fat diet affects the balance between good and bad bacteria in the gut. (qualitycounts.com)
  • In animals, activation of the protein ataxia telangiectasia mutated (ATM) using the antimalarial drug chloroquine improves features of metabolic syndrome and decreases atherosclerosis, a build-up of fatty plaque within arteries. (clinicaltrials.gov)
  • To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors. (mja.com.au)
  • receptor substrate
  • The molecular mechanisms underlying this linkage, however, are poorly understood, although TNF-α has been shown to cause insulin resistance by increasing serine phosphorylation of insulin receptor substrate (IRS)-1 ( 6 ). (pnas.org)
  • insulin receptor substrate (IRS)-1 or -2, phosphatidylinositol 3-kinase (PI3-K), protein kinase B (PKB) or glucose transporter (GLUT) 4, or the regulation of lipolysis rate. (diva-portal.org)
  • rates of metabolic
  • Four DHBs have systems for measuring their rates of metabolic monitoring. (nzma.org.nz)
  • Global rates of metabolic syndrome are on the rise and the results of the present study suggest Montmorency tart cherries, in juice or capsule form, could exert beneficial effects for adults with this condition when incorporated into an overall healthy diet," said Desai. (eurekalert.org)
  • clinically
  • Belly fat, known clinically as central obesity, has been linked to the development of asthma in a new study. (nutritionreview.org)
  • There is no consensus on who is clinically responsible for metabolic monitoring. (nzma.org.nz)
  • The U.K. researchers found Montmorency tart cherry juice led to a significant, clinically-relevant reduction in systolic blood pressure when compared to the placebo 2 hours after consumption, and Montmorency tart cherry juice and Montmorency tart cherry capsules both lowered insulin levels significantly more than the placebo at 1 hour and 3 hours, respectively. (eurekalert.org)
  • cardiometabolic
  • As PCOS seems to be dominated by metabolic consequences, both as a consequence of the condition and as a vector for further complications, including DM2, CVD, and the exacerbation of the reproductive features of the syndrome (hirsutism and an/oligoovulation) [ 5 ], it is evident that research on the metabolic and cardiometabolic features of PCOS is needed. (hindawi.com)
  • The search was conducted with a combination of terms that included "PCOS," "cardiometabolic," "cardiovascular disease," "metabolic syndrome," "insulin resistance," and "obesity" that were assumed to be relevant. (hindawi.com)
  • obese children
  • No significant correlations were found between AHI, lowest arterial oxygen saturation, or arousal index and serum insulin, serum glucose, I/G ratio, HOMA, or serum lipids for either the whole group or the obese children only. (aappublications.org)
  • Diseases
  • Lately, it is increasingly being recognized that psoriasis is not merely a skin disease but is probably associated with other co-morbidities such as psoriatic arthritis, Crohn's disease, the metabolic syndrome and cardio-vascular diseases (CVD). (clinicaltrials.gov)
  • 1) Robert Drapkin, M.D. , a board-certified physician in Internal Medicine, Medical Oncology and Palliative Care, warns against the dangers of poor health habits, and encourages American's to become a good example of health through knowledge, to prevent and eliminate metabolic diseases. (prweb.com)
  • Rather than taking another pill, I want to educate and show examples of how good health through knowledge can prevent and even eliminate metabolic diseases. (prweb.com)
  • cholesterol
  • While men conceived by ICSI, but not women, had lower mean HDL cholesterol concentrations in comparison to controls, other markers of the metabolic syndrome were not affected by the mode of conception. (hindawi.com)
  • complications
  • Recent evidences also suggest that they may serve as valuable molecule for the treatment of obesity related health complications. (biomedcentral.com)
  • Through these diverse mechanisms hydroxycinnamic acid derivatives reduce obesity and curtail associated adverse health complications. (biomedcentral.com)
  • pathways
  • All these biological activities are mainly regulated by phenolic acid's ability to scavenge free radicals generated due to excess nutrition supply to the tissues in obesity, or they may regulate the energy homeostasis and inflammatory pathways. (biomedcentral.com)
  • disorder
  • Although PCOS is diagnosed exclusively based on reproductive criteria, it is also a metabolic disorder. (hindawi.com)
  • It is a heterogeneous disorder of uncertain etiology, but there is strong evidence that complex interactions between genetic, environmental, and behavioral factors contribute to causing this syndrome [ 1 ]. (hindawi.com)
  • Although the diagnosis of PCOS is based exclusively on reproductive criteria (hyperandrogenism, oligo/anovulation, and/or PCO on ultrasound) [ 4 ], and management tends to focus primarily on treatment of infertility and hirsutism [ 5 ], PCOS is also a metabolic disorder. (hindawi.com)
  • The syndrome substantially increases the risk of developing diabetes and vascular disease, but there is no clear unifying approach to treat this disorder. (clinicaltrials.gov)
  • study
  • In this study, we show that SOCS-1 and -3 are increased in insulin-resistant obese animals, and that insulin resistance can be induced in vivo by overexpression of SOCS-1 or -3 in liver using adenoviral vectors. (pnas.org)
  • Ben Brumpton, from the Norwegian University of Science and Technology, said: "Asthma can affect people of all sizes, but our study has highlighted both the individual and combined effect of central obesity and overall obesity on asthma development. (nutritionreview.org)
  • Bosy-Westphal A, Onur S, Geisler C, Wolf A, Korth O, Pfeuffer M, Schrezenmeir J, Krawczak M, Müller MJ (2006) Common familial influences on clustering of metabolic syndrome traits with central obesity and insulin resistance: the Kiel obesity prevention study. (springer.com)
  • The purpose of this study is to define the mechanism(s) through which Obstructive Sleep Apnea/Hypopnea (OSAH) promotes abnormal metabolic processes which characterize the metabolic syndrome. (clinicaltrials.gov)
  • Aim: 3: Using microarray data from peripheral monocytes, we will explore if specific gene expression patterns after the study conditions are associated with alterations consistent with metabolic syndrome. (clinicaltrials.gov)
  • The aim of this study was to elucidate the interplay between hormones, nutrients and adipose depots in normal and insulin-resistant fat cell metabolism. (diva-portal.org)
  • and International Association for the Study of Obesity. (nzma.org.nz)
  • The objective of the present study was to determine the suitability of a swine breed with leptin resistance and predisposition to obesity (the Iberian pig) as model for studies on metabolic syndrome and type 2 diabetes. (hindawi.com)
  • 1988
  • The literature proliferation popularised the concept of the 'metabolic syndrome', which, like a young prince, grew rapidly from its baptism in 1988, confirmation by the WHO [ 3 ] in 1999 and ultimate coronation in heavily sponsored world conferences held in its own name. (springer.com)
  • fatty
  • Here we show that overexpression of suppressors of cytokine signaling (SOCS)-1 and SOCS-3 in liver causes insulin resistance and an increase in the key regulator of fatty acid synthesis in liver, sterol regulatory element-binding protein (SREBP)-1c. (pnas.org)
  • Nonalcoholic fatty liver, also a component of the metabolic syndrome, is the most common liver abnormality in the U.S. and may lead to hepatic fibrosis, cirrhosis, and death ( 2 ). (pnas.org)
  • High levels of free fatty acids (FFAs) induce insulin resistance in muscle and liver in vivo. (diva-portal.org)
  • cortisol
  • Glucocorticoids, e.g. cortisol, exert pronounced insulin-antagonistic effects and are associated with redistribution of fat from peripheral to central fat depots in humans. (diva-portal.org)
  • Treatment of human subcutaneous and omental adipocytes in vitro, with the cortisol analogue dexamethasone, resulted in a dose dependent down-regulation of basal and insulin-stimulated glucose uptake capacity in omental, but not in subcutaneous cells. (diva-portal.org)
  • features
  • The pig is emerging rapidly as a biomedical model for energy metabolism and obesity in humans because it shares several similarities with humans: omnivorous habits, propensity to sedentary behaviour and fattening, and similar metabolic and cardiovascular features [ 10 - 13 ]. (hindawi.com)