• A tumor is an abnormal growth of body tissue. (wikipedia.org)
  • Tumor development has been promoted in mice exposed to 2,4-dichlorophenol which was nonmutagenic in the Ames assay and produced abnormal fetuses in mice. (cdc.gov)
  • A neuroblastoma may arise from sympathetic nervous tissue anywhere in the body, but this tumor most often develops in the abdomen. (aafp.org)
  • A tumor of the musculoskeletal system is often first detected when trauma appears to cause pain and dysfunction out of proportion to the injury. (aafp.org)
  • Some people with Aicardi-Goutières syndrome have features characteristic of autoimmune disorders, which occur when the immune system malfunctions and attacks the body's own systems and organs. (medlineplus.gov)
  • Neuro-ophthalmic manifestations frequently are encountered in persons with multiple sclerosis (MS) and other central nervous system (CNS) inflammatory disorders, including neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD). (medscape.com)
  • This review focuses on the structure of ADAM17, its signaling in the cardiovascular system and its participation in certain disorders involving the heart, blood vessels, and neural regulation of autonomic and cardiovascular modulation. (frontiersin.org)
  • This deficiency could cause a host of problems ranging from indigestion, stunted growth, nervous disorders, or worse. (shirleys-wellness-cafe.com)
  • Workers exposed to 4-chlorophenol have demonstrated signs of functional disorders of the central and peripheral nervous systems and mucous membrane structure. (cdc.gov)
  • The 18-kDa translocator protein (TSPO) is increasingly recognized as a molecular target for PET imaging of inflammatory responses in various central nervous system (CNS) disorders. (iasp-pain.org)
  • Both are central nervous system disorders and both have the same outcome of error and difficulty in speech. (differencebetween.net)
  • Some patients with retinal abnormalities have been found to have abnormal visual acuity. (drugs.com)
  • Partial Fetal Alcohol Syndrome - diagnosis used when the infant does not meet the full FAS diagnostic criteria but was exposed to alcohol before birth, presents some facial abnormalities, a growth problem and malfunctions of the central nervous system. (dallasexaminer.com)
  • Patterns of hair growth can be abnormal, serving as external markers of underlying structural brain and central nervous system abnormalities. (medscape.com)
  • Cerebral palsy (CP) is characterized by abnormalities in the controlled or postural movements of the body secondary to central nervous system injury, damage, or dysfunction, and is not known to be the result of a progressive or degenerative brain disease 1-2 . (bvsalud.org)
  • But it appears to cause issues with the central nervous system and bodily reflexes. (healthline.com)
  • The clinical picture usually involves delayed motor development, persistence of primitive reflexes, presence of abnormal reflexes, and deficient development of protective reflexes 1 . (bvsalud.org)
  • If you have abnormal heart rhythm (heart block) and you are taking this medicine, contact your doctor immediately if you feel one or more of the following symptoms: fainting, short-lasting loss of consciousness, dizziness or light-headedness, fatigue (tiredness), shortness of breath, chest pain, irregular heart-beat or confusion. (medicines.org.uk)
  • Problems with the body's immune system can lead to tumors. (wikipedia.org)
  • Multiple sclerosis is a disease that involves an immune-mediated process that results in an abnormal response in the body's immune system that damages central nervous system (CNS) tissues in which the immune system attacks myelin, the substance that surrounds and insulates nerve fibers causing demyelination that leads to nerve damage. (medicinenet.com)
  • A pediatric ocular imaging system (RetCam3) may be used in newborns, infants, and uncooperative children. (medscape.com)
  • Abnormal liver function, jaundice and liver failure. (medindia.net)
  • In extremely rare cases, affected individuals may experience abnormal enlargement of the liver and/or spleen (hepatosplenomegaly). (rarediseases.org)
  • Patients with neuropathy typically present with symptoms of pain, tingling, or numbness in their feet, consistent with dysfunction affecting the longest and largest fibers of the peripheral nervous system (PNS). (medscape.com)
  • Sensory neuron dysfunction results in abnormal or lost sensation. (msdmanuals.com)
  • General scientific consensus states that CJD occurs due to abnormal changes to cellular proteins called prions. (healthline.com)
  • In brief, prions perform a specific function within cells and is most abundant in the central nervous system. (healthline.com)
  • When you develop sporadic or inherited CJD, one of the proteins responsible for creating prions becomes abnormal and produces an infected prion. (healthline.com)
  • It causes proteins to fold, creating abnormal protein formations called prions. (wyo.gov)
  • These prions disrupt normal nervous system functions, and as the disease progresses, animals become lethargic, have progressive weight loss, and eventually die. (wyo.gov)
  • Patients with renal and central nervous involvement were excluded from the study. (bmj.com)
  • Filamin A is mutated in X-linked chronic idiopathic intestinal pseudo-obstruction with central nervous system involvement. (nih.gov)
  • DEXTROCARDIA) and/or abnormal SPLEEN (e.g., asplenia and polysplenia). (bvsalud.org)
  • A 5-week-old female infant born at 38 weeks presents to her pediatrician with abnormal eye movements. (contemporarypediatrics.com)
  • Due to abnormal movements of the facial muscles, compounded by impairment of the self-cleansing mechanism of the oral cavity, patients with this condition can develop oral diseases such as caries, periodontal disease, and tooth loss. (bvsalud.org)
  • The inflammation may be in the bowel itself or in the centers of the mid-brain where the regulatory (rhythmic) functions of the digestive system-and all the other automatic functions of the body-are controlled. (autism.org)
  • Chest pain, abnormal heart rate, low blood pressure, abnormal heart rhythm with QT prolongation and torsades de pointes. (medindia.net)
  • Leukemia should be suspected if persistent vague symptoms are accompanied by evidence of abnormal bleeding, bone pain, lymphadenopathy or hepatosplenomegaly. (aafp.org)
  • Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. (medscape.com)
  • Sporadic CJD occurs when normal proteins spontaneously mutate to the abnormal prion type. (healthline.com)
  • It inhibits the activities of the helminth-specific mitochondrial enzyme fumarate reductase, thereby stopping the citric acid cycle or Krebs cycle, which is the system used by all aerobic organisms to release stored energy through the oxidation of acetyl coenzyme A (acetyl-CoA) derived from carbohydrates, fats, and proteins into carbon dioxide. (naturalpedia.com)
  • The symptoms and physical findings associated with Rosai-Dorfman disease vary greatly from one person to another depending upon the extent of the disorder and the specific organ systems affected. (rarediseases.org)
  • Patients should be monitored carefully for dose-related adverse reactions, particularly nervous system symptoms (see sections 4.3 and 4.4). (who.int)
  • Dysarthria results from a neurological injury of the motor component of the motor speech system i.e. the neuromuscular system involved in talking. (differencebetween.net)
  • Addiction is a disorder of the brain's reward system which arises through transcriptional and epigenetic mechanisms and occurs over time from chronically high levels of exposure to an addictive stimulus (e.g., morphine, cocaine, sexual intercourse, gambling, etc. (wikipedia.org)
  • When heart failure occurs along with the collection of an abnormal protein in the heart tissue (cardiac amyloidosis), an alternative therapy may be prescribed by the doctor. (medicines.org.uk)
  • The infected prion then spread through the central nervous system in a chain reaction or like dominoes getting knocked over until it eventually reaches the brain and causes the development of lesions or holes. (healthline.com)
  • Dysarthria is disrupted muscular control due to lesions of either the central or the peripheral nervous systems, meaning there will be difficulty in pronunciation of words. (differencebetween.net)
  • The body has peripheral and central thermoreceptors. (nih.gov)
  • On the other hand, the peripheral and central mechanisms of tonic immobility were intensely investigated at a behavioural and a neuronal level in stick insects and crickets. (nhbs.com)
  • Mutations in any of these genes are believed to result the absence or abnormal functioning of the respective nuclease enzyme. (medlineplus.gov)
  • The aim of this paper is to report a case of a patient with cerebral palsy who presented with absence of the maxillary central incisors, removable prosthesis wear, and oral candidiasis. (bvsalud.org)
  • If unequivocal hyperglycemia is absent, two abnormal test results are required for diagnosis, using the same sample or two separate test samples. (medscape.com)
  • L4s migrate through tissues and the blood vascular system for several weeks. (capcvet.org)
  • Infants with suspected pathology may benefit from a focused reassessment, an in-depth family history, and a careful inventory of atypical or abnormal hair characteristics. (medscape.com)
  • Irregularidades en el sistema nervioso central, esqueleto y tracto urinario a menudo se asocian con el síndrome. (bvsalud.org)
  • A paralisia cerebral é uma anormalidade causada por lesões no sistema nervoso central que podem ocorrer durante o período pré, peri ou pósnatal. (bvsalud.org)
  • The results of surveys, analyses, and studies are made known through a number of data release mechanisms including publications, mainframe computer data files, CD-ROMs (Search and Retrieval Software, Statistical Export and Tabulation System (SETS)), and the Internet. (cdc.gov)
  • Abnormal results include higher and lower glucose levels. (stlukes-stl.com)
  • It is best thought of as being part of the holoprosencephaly spectrum (see classification system for midline malformations ). (radiopaedia.org)