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  • short amino
  • A nuclear export signal (NES) is a short amino acid sequence of 4 hydrophobic residues in a protein that targets it for export from the cell nucleus to the cytoplasm through the nuclear pore complex using nuclear transport. (wikipedia.org)
  • Genetics
  • Centre for Applied Genomics and Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. (nih.gov)
  • GeneDB, a pathogen sequence database MEROPS, a peptidase database Mouse Genetics Project, including a database of standardised phenotypic analysis for many hundreds of mutant mice. (wikipedia.org)
  • 1993
  • In 1993 the then 17 Sanger Centre staff moved into temporary laboratory space at Hinxton Hall in Cambridgeshire. (wikipedia.org)
  • alignment
  • On this relatively simple system, we developed a sequence alignment method based on artificial neural networks that allows insertions and deletions in the alignment. (dtu.dk)
  • The NetMHC-4.0 method for the prediction of peptide-MHC class I binding affinity using gapped sequence alignment is publicly available at: http://www.cbs.dtu.dk/services/NetMHC-4.0. (dtu.dk)
  • Lawrence has particular contributions in the development of sequence alignment algorithms, which is approaching the modif finding problem by integrating the Bayesian statistics and Gibbs sampling strategy. (wikipedia.org)
  • molecules
  • The RNA molecules from the biological sample are called targets , and the polymers of nucleic acids fixed on the surface are called probes . (biomedcentral.com)
  • The encoded information is contained and conveyed via the nucleic acid sequence, which provides the 'ladder-step' ordering of nucleotides within the molecules of RNA and DNA. (wikipedia.org)
  • alleles
  • The sequence type is then determined by the combination of alleles identified. (asm.org)
  • Unique sequences (alleles) are assigned a random integer number, and a unique combination of alleles at each locus, an "allelic profile," specifies the sequence type (ST). Following the introduction of the Neisseria MLST scheme, MLST has been considered the "gold standard" of typing, and additional schemes that cover bacterial and fungal species have been developed. (asm.org)
  • Tissue
  • Tissue selection is an important factor to consider for eQTL analysis. (royalsocietypublishing.org)
  • The gene tends to have expression correlated to lymphatic system, vascular/arterial endothelial tissue, and notable expression in the bladder based on expression profiles and microarray analysis. (wikipedia.org)
  • We applied the workflow to 686 sequencing libraries from 252 cancer samples of different cancer and tissue types, 32 non-template controls, and 24 test samples. (mdpi.com)
  • functional
  • Additionally, they are designed to facilitate scientific exploration in the areas of functional curation, pathogenicity, therapeutics, comparative analysis and functional genomics. (wikipedia.org)