DNA DamageDNA RepairComet AssayAtaxia Telangiectasia Mutated ProteinsCell Cycle ProteinsUltraviolet RaysTumor Suppressor Protein p53DNA-Binding ProteinsProtein-Serine-Threonine KinasesCheckpoint Kinase 2Signal TransductionCell CycleApoptosisOxidative StressTumor Suppressor ProteinsDNA Breaks, Double-StrandedDeoxyguanosineGamma RaysCell LinePhosphorylationNuclear ProteinsDNACell Line, TumorMethyl MethanesulfonateHistonesMutationCell SurvivalMutagensCells, CulturedG2 PhaseGenomic InstabilityDNA ReplicationFibroblastsProtein KinasesReactive Oxygen SpeciesHeLa CellsHydrogen PeroxideDose-Response Relationship, RadiationDNA Repair EnzymesRadiation ToleranceModels, BiologicalProtein BindingMolecular Sequence DataDNA AdductsPoly(ADP-ribose) PolymerasesGenes, cdcCell Cycle CheckpointsTime FactorsCell NucleusSaccharomyces cerevisiae ProteinsIntracellular Signaling Peptides and ProteinsDNA Breaks, Single-StrandedRad51 RecombinaseSaccharomyces cerevisiaeGene Expression RegulationS PhaseBRCA1 ProteinRNA, Small InterferingDNA BreaksMitosisCell AgingEnzyme ActivationCell DeathBlotting, WesternTranscription, GeneticHydroxyureaDNA-Activated Protein KinaseCell ProliferationDNA GlycosylasesMicronucleus TestsAmino Acid SequenceChromatinTumor Cells, CulturedDose-Response Relationship, DrugTranscription FactorsRNA, MessengerHCT116 CellsCyclin-Dependent Kinase Inhibitor p21TransfectionRNA InterferenceAntioxidantsBase SequenceMice, KnockoutOxidation-ReductionReplication Protein AX-RaysG2 Phase Cell Cycle CheckpointsCell DivisionMice, Inbred C57BLUbiquitinationPoly Adenosine Diphosphate RiboseProto-Oncogene Proteins c-mdm2Ataxia TelangiectasiaProtein Structure, TertiaryDNA HelicasesRecombinational DNA RepairNucleic Acid Synthesis InhibitorsAntineoplastic AgentsFlow CytometryOxidants