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  • malignant
  • Malignant melanoma (see the image below) is a neoplasm of melanocytes or a neoplasm of the cells that develop from melanocytes. (medscape.com)
  • The pathological study showed malignant epithelial neoplasm which is composed of glands of irregular shapes, anastomosing with cribriform (Figure 2 ) and papillary (Figure 3 ) arrangements whose cells have a cylindrical shape with a high ratio nucleus/cytoplasm, hyperchromatic nuclei, with evident nucleoli, frequent mitotic figures, and vacuolated cytoplasm. (hindawi.com)
  • Ideally, these anticancer drugs should interfere only with cellular processes that are unique to malignant cells. (brilliantnurse.com)
  • Cutaneous malignant melanoma (CMM) is a neoplasm generated through the malignant transformation of epidermal melanocytes, the cells which normally reside in the basal layer of the epidermis and produce the skin pigment melanin ( Figure 1A - C ). Noncutaneous melanomas can also develop at other sites populated by melanocytes such as choroidal layer of the eye, respiratory, gastrointestinal, and genitourinary mucosal surfaces, or the meninges. (intechopen.com)
  • Diagnosis
  • This chapter provides an extended, updated biological status of TRP2/L-DCT encompassing the structural and functional particularities within melanoma molecularity, in the attempt to get new insights into the complex mechanisms of this neoplasm and raise the interest for DCT unexplored yet potential in melanoma diagnosis/prognosis and therapy. (intechopen.com)