Models, BiologicalCell LineInclusion BodiesCells, CulturedRotenoneCell Line, TumorFriedreich AtaxiaHuntington Diseasealpha-SynucleinSignal TransductionMutationParkinson DiseaseApoptosisMolecular Sequence DataNeuronsGene Expression RegulationDrug Evaluation, PreclinicalBiological ProductsLong-Term Potentiation1-Methyl-4-phenylpyridiniumTransfectionCell SurvivalGene Expression ProfilingPC12 CellsProtein BindingBlotting, WesternTime FactorsTrinucleotide Repeat ExpansionCell DifferentiationRNA, MessengerBiological AssayAmino Acid SequencePeptidesCell DeathBiological TherapyCell Line, TransformedInduced Pluripotent Stem CellsCell ProliferationNerve Tissue ProteinsIron-Binding ProteinsPhosphorylationDisease Models, AnimalReverse Transcriptase Polymerase Chain ReactionFibroblastsDose-Response Relationship, DrugEnzyme InhibitorsMitochondriaGreen Fluorescent ProteinsPhenotypeDoxycyclineOligonucleotide Array Sequence AnalysisHep G2 CellsTumor Cells, CulturedNeurodegenerative DiseasesBase SequenceProteasome Endopeptidase Complextau ProteinsNuclear ProteinsRecombinant ProteinsGene ExpressionAutophagyTranscription FactorsProtein TransportMice, TransgenicBiological WarfareMicroscopy, FluorescenceNeuroprotective AgentsCytoprotectionImmunohistochemistryTranscription, GeneticHEK293 CellsBiological MarkersBiological ProcessesRNA, Small InterferingEpithelial CellsCOS CellsOxidative StressNeuroblastomaKineticsCricetulusMicroscopy, ConfocalCalciumBiological TransportCricetinaeCell NucleusAlgorithmsRats, Sprague-DawleyComputational BiologyHeLa CellsUp-RegulationMembrane Potential, MitochondrialPromoter Regions, GeneticMitochondrial ProteinsSynapsesHydrogen PeroxideRecombinant Fusion ProteinsDown-RegulationGene Expression Regulation, NeoplasticCell Culture TechniquesDNA Primers