DNA DamageAtaxia Telangiectasia Mutated ProteinsDNA RepairCell Cycle ProteinsTumor Suppressor ProteinsProtein-Serine-Threonine KinasesDNA-Binding ProteinsNuclear ProteinsCheckpoint Kinase 2Cell LineRadiation, IonizingTumor Suppressor Protein p53DNA ReplicationDNA Breaks, Double-StrandedHistonesPhosphorylationCell CycleComet AssayGenomic InstabilitySignal TransductionUltraviolet RaysCell Cycle CheckpointsDNAGamma RaysBRCA1 ProteinDNA BreaksDNA Repair EnzymesTelomereCell Line, TumorApoptosisG2 Phase Cell Cycle CheckpointsG2 PhaseCell AgingDNA-Activated Protein KinaseHeLa CellsRadiation ToleranceMutationS PhaseProtein KinasesGenes, cdcTelomeric Repeat Binding Protein 2Intracellular Signaling Peptides and ProteinsMethyl MethanesulfonateReplication Protein AUbiquitinationRad51 RecombinaseMutagensChromatinMitosisFibroblastsDNA End-Joining RepairRecombinational DNA RepairRNA, Small InterferingLaser Scanning CytometryHomologous RecombinationCell SurvivalTelomere-Binding ProteinsPoly(ADP-ribose) PolymerasesDNA Breaks, Single-StrandedChromosomal Proteins, Non-HistoneCyclin-Dependent Kinase Inhibitor p21HydroxyureaHCT116 CellsCells, CulturedCell NucleusSaccharomyces cerevisiae ProteinsAtaxia TelangiectasiaDNA, ViralRNA InterferenceProtein BindingDeoxyguanosineOxidative StressRecombination, GeneticDose-Response Relationship, RadiationUbiquitin-Protein LigasesFanconi Anemia Complementation Group D2 ProteinNucleic Acid Synthesis InhibitorsModels, BiologicalSaccharomyces cerevisiaeChromatin Assembly and DisassemblyMolecular Sequence DataChromosomal InstabilityCell ProliferationUbiquitinHEK293 CellsGene Knockdown TechniquesAntigens, NuclearBase SequenceDNA, NeoplasmDNA AdductsNeoplasmsFlow CytometryEndodeoxyribonucleasesFanconi AnemiaPoly Adenosine Diphosphate RiboseExodeoxyribonucleasesBlotting, WesternEnediynesCell Transformation, NeoplasticDNA Helicases