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  • proliferation
  • GelMA ShyMs, with dual media exposure, were found to be compatible with both the cell-seeding and the cell-encapsulation approach as tested using murine 10T1/2 cells and demonstrated higher cellular spreading and proliferation as compared to flat GelMA unsuspended control. (asme.org)
  • vertebrate
  • A conspicuous feature of the vertebrate embryonic CNS is the absence of a homogeneous gradient of neurogenesis across the neural tube, young post-mitotic neuroblasts arise at discrete patches of the neuroepithelium in a disjoined spatiotemporal pattern. (biologists.org)
  • neurons
  • Strikingly, the MH is also characterized by a distinct pattern of neurogenesis at early stages: mesencephalic and anterior rhombencephalic neurons are separated by a neuron-free, transverse stripe of delayed differentiation (hereafter referred to as `intervening zone', IZ), precisely located at the level of the MHB. (biologists.org)
  • approaches
  • In this review, we summarize and examine the recent advances in application of engineering and biomaterial-based approaches to control ESC differentiation. (asme.org)
  • We focus on physical strategies (e.g., geometrical constraint, mechanical stimulation, extracellular matrix (ECM) stiffness, and topography) and biochemical approaches (e.g., genetic engineering, soluble bioactive factors, coculture, and synthetic small molecules), and highlight the three-dimensional (3D) hydrogel-based microenvironment for directed ESC differentiation. (asme.org)
  • The first of these to be identified was MyoD , which was isolated by subtractive hybridization approaches in an inducible differentiation system in which multipotential 10T1/2 cells were converted to skeletal muscle through treatment with the DNA hypomethylating agent 5-azacytidine. (ahajournals.org)
  • cells
  • To combat these insults, cells have evolved DNA damage checkpoint signaling as a surveillance mechanism to sense DNA damage and direct cellular responses to DNA damage. (jove.com)
  • The transcript corresponding to the RBP2 isoform containing the C-terminal PHD accumulates during differentiation of promonocytic, lymphoma-derived, U937 cells into monocytes 2 . (jove.com)
  • This approach could not be used to investigate the dynamic nature of cellular processes or pathogenic events that occur in a subset of cells. (jove.com)
  • These reporter cell lines will also facilitating purification of these marked cells from within a background of non-specific differentiation. (mcmaster.ca)
  • 2005). Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite side of the same coin. (mcmaster.ca)
  • describe
  • In addition, a roundness measure of the embryonic mouth opening is used to describe the shape of the mouth. (jove.com)
  • progress
  • Further progress in evaluating the function of mammalian Gata4 has been limited, in large part, because of the early embryonic lethality of the knockout mouse embryos (E7.0-9.5). (biologists.org)
  • Progress in this field has been hampered by the lack of an inducible in vitro system for study of the early steps of smooth muscle differentiation. (ahajournals.org)
  • early
  • After isolating embryonic ventral halves at early and late gastrulation, we analyze the transcriptional response to these molecules within the generated ectopic organizers using oligonucleotide microarrays. (biomedcentral.com)
  • various
  • HCS is the cell-based quantification of several processes simultaneously, which provides a more detailed representation of the cellular response to various perturbations compared to HTS. (jove.com)