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  • mRNA
  • A necessary step in attaining such a goal is to first produce an mRNA transcript from a plasmid containing the open reading frame (ORF) for a transcription factor for cellular activation. (usm.edu)
  • organism
  • Further studies will be required to identify the precise mechanism of TPC action and their link with NAADP signalling, as well as relating this to their roles in differentiation and other key processes in the cell and organism. (ovid.com)
  • In terms of cellular composition, V. carteri is about as simple as a multicellular organism can be, yet it shares many features that characterize the life cycles and developmental histories of much more complex, higher organisms. (biomedcentral.com)
  • H. volcanii demonstrates some biofilm phenotypes similar to bacterial biofilms, but also has interesting phenotypes that may be unique to this organism or to this class of organisms, including changes in cellular morphology and an unusual form of social motility. (biomedcentral.com)
  • Dictyostelium is dealt, firstly, according to cell differentiation and pattern formation common in this type of organism. (elsevier.com)
  • cells
  • Our results indicated that antigen-sensitive units were unipotent for they displayed in the spleens of unprimed donors the same restrictions of function and heterogeneity (antibody-specificity differentiation, antibody-class differentiation) found among antibody-forming cells. (rupress.org)
  • We concluded that relatively advanced differentiation of potentially competent cells occurs before sheep erythrocyte administration. (rupress.org)
  • In this review, we focus on the role of TATA-box associated factor 4 (TAF4) and its functional isoforms generated by alternative splicing in controlling lineage-specific differentiation of normal mesenchymal stem cells and cancer stem cells. (mdpi.com)
  • Specialized cells are the product of differentiation. (thefreedictionary.com)
  • Remarkably, neural differentiation of P19 cells leads to dramatically reduced SRSF5 shuttling. (rupress.org)
  • This study provides the first integrated picture of the interplay between transcription factors, proximal promoter activity, and RNA transcripts required for differentiation of human leukemia cells. (biomedcentral.com)
  • The investigation of the role of NAADP and TPCs in differentiation is still at an early stage, but recent studies have suggested that they are important mediators of differentiation of neurones, skeletal muscle cells and osteoclasts. (ovid.com)
  • To visualize the extracellular matrix, biofilms formed by GFP-expressing cells were stained with concanavalin A, DAPI, Congo red and thioflavin T. Stains colocalized with larger cellular structures and indicated that the extracellular matrix may contain a combination of polysaccharides, extracellular DNA and amyloid protein. (biomedcentral.com)
  • Our results revealed that OPCs and HOG cells cultured under differentiation conditions became more susceptible to HSV-1. (blogspot.com)
  • From these colonial organisms, natural selection generated more complex forms with cellular differentiation, with cells specialized in vegetative (i.e., soma) and reproductive (i.e., germ) functions. (docplayer.net)
  • tissue
  • On the basis of these reports and of the observations on tissue differentiation and IAA distribution in defective endosperm-B18 mutant and in N -1-naphthylphthalamic acid-treated kernels, a model for ZmPIN1-mediated transport of auxin and the related auxin fluxes during maize kernel development is proposed. (plantphysiol.org)
  • Development
  • To further evaluate the Klf7 function in the central nervous system development, I have compared self-renewal and neuronal differentiation ability of wt and Klf7-KO derived neurospheres. (unina.it)
  • Advances in biofilm biology have been made over decades for model bacterial species, and include characterizations of social behaviors and cellular differentiation during biofilm development. (biomedcentral.com)
  • starvation
  • As a result, responding to starvation requires a gene regulatory network that can detect the availability of a variety of nutrients and integrate this information into the cellular response. (embopress.org)
  • approaches
  • Engineering and biomaterial-based approaches to recreate a biomimetic cellular microenvironment provide valuable strategies for directing ESCs differentiation to specific lineages in vitro. (asme.org)
  • In this review, we summarize and examine the recent advances in application of engineering and biomaterial-based approaches to control ESC differentiation. (asme.org)
  • We focus on physical strategies (e.g., geometrical constraint, mechanical stimulation, extracellular matrix (ECM) stiffness, and topography) and biochemical approaches (e.g., genetic engineering, soluble bioactive factors, coculture, and synthetic small molecules), and highlight the three-dimensional (3D) hydrogel-based microenvironment for directed ESC differentiation. (asme.org)
  • function
  • These results demonstrate that Spo14 PLD catalytic activity and cellular function can be differentially regulated at the level of phosphatidylcholine hydrolysis. (genetics.org)
  • researchers
  • Conclusions The method presented here represents a useful framework to assist researchers in the field of cellular reprogramming to design experimental strategies with potential applications in the regenerative medicine and disease modelling. (isvhld2012.org)
  • Given the increasing interest of cellular reprogramming in regenerative medicine and basic research, our method Tariquidar Cd14 represents a useful computational methodology to assist researchers in developing experimental strategies. (isvhld2012.org)
  • further
  • A concentration yield of 4.2g/L of the RNA transcript was obtained (Figure 9) and stored for further downstream cellular differentiation and innate immune response application. (usm.edu)
  • regulatory
  • GRNs generated with biological properties as that of regulatory network, and selective six different biological examples of cellular reprogramming. (isvhld2012.org)
  • Differential stability analysis takes as input a gene regulatory network and experimental manifestation data comparing initial and final cellular phenotypes. (isvhld2012.org)
  • Analysis
  • The output of the analysis … Number 3 Differential stability analysis: quality recipes for cellular reprogramming in three methods. (isvhld2012.org)
  • stage
  • Finally, electron microscopy assays indicated that HSV-1 may be also entering OLs by macropinocytosis depending on their differentiation stage. (blogspot.com)
  • effective
  • Software to six biologically relevant good examples finds experimental validation in literature for the recognized units of RDs as effective inducers of transitions between cellular phenotypes. (isvhld2012.org)