DNA DamageDNA RepairComet AssayImmunohistochemistryApoptosisAtaxia Telangiectasia Mutated ProteinsCell CycleCells, CulturedCell LineCell Line, TumorCell Cycle ProteinsUltraviolet RaysTime FactorsFibroblastsMutationDeoxyguanosinePhosphorylationCell DifferentiationCell NucleusCheckpoint Kinase 2Tumor Suppressor Protein p53DNA-Binding ProteinsFluorescent Antibody TechniqueSignal TransductionProtein-Serine-Threonine KinasesDNA Breaks, Double-StrandedOxidative StressPhenotypeRNA, MessengerMolecular Sequence DataEpithelial CellsTumor Suppressor ProteinsNeuronsFlow CytometryGamma RaysBlotting, WesternTumor Cells, CulturedMicroscopy, ElectronCell ProliferationCell DivisionDNAHistonesMethyl MethanesulfonateMutagensNuclear ProteinsGenomic InstabilityG2 PhaseDNA ReplicationMice, Inbred BALB CDose-Response Relationship, RadiationCell SurvivalDNA Repair EnzymesAntibodies, MonoclonalDNA AdductsReactive Oxygen SpeciesHydrogen PeroxideCell MovementCalciumDNA BreaksProtein KinasesRadiation TolerancePoly(ADP-ribose) PolymerasesGenes, cdcCell Cycle CheckpointsHeLa CellsDNA Breaks, Single-StrandedRad51 RecombinaseDNA GlycosylasesSaccharomyces cerevisiae ProteinsS PhaseBRCA1 ProteinMitosisSaccharomyces cerevisiaeCell AgingMicronucleus TestsModels, BiologicalAntioxidantsProtein BindingHydroxyureaIntracellular Signaling Peptides and ProteinsChromatinG2 Phase Cell Cycle CheckpointsX-RaysDNA-Activated Protein KinaseAlkylating AgentsReplication Protein AOxidation-ReductionBase SequenceRecombinational DNA RepairCell DeathDNA HelicasesRNA, Small InterferingRecombination, GeneticPoly Adenosine Diphosphate RiboseDose-Response Relationship, DrugProto-Oncogene Proteins c-mdm2SOS Response (Genetics)Amino Acid SequenceMitomycinHCT116 Cells