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  • nucleolar
  • A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching. (sigmaaldrich.com)
  • Our findings suggest that directional nucleolar transit is important for the physiological function of AID and demonstrate that nuclear/nucleolar import and DNA cytosine deamination together define the biological activity of AID. (sigmaaldrich.com)
  • peptide
  • PTHrP mutants from a human PTHrP (-36/+139) cDNA (wild type) cloned into pcDNA3.1 plasmid with deletion (Δ) of the signal peptide (SP), NLS, T(107), or T107A replacing T(107) by A(107) were generated and stably transfected into osteoblastic MC3T3-E1 cells. (sigmaaldrich.com)
  • The distribution of quantum dots is affected by a TATHA2 peptide sequence in live cells. (spie.org)
  • lipid
  • Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis. (abcam.com)
  • fibroblasts
  • A Travelling Fellowship from Journal of Cell Science allowed her to spend time in Prof Maddy Parson's lab at King's College London, learning new cell migration assays and analysing fibroblasts cultured from individuals with Parkinson's. (biologists.org)
  • Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53-dependent senescence and favors cell transformation. (abcam.com)
  • epithelial
  • inhibits epithelial-mesenchymal transition, migration and invasion of colorectal cancer cells through Rac1-JNK pathway. (abcam.com)
  • Imaging
  • Wiraja C, Yeo DC, Tham KC, Chew SWT, Lim X, Xu C . Real-Time Imaging of Dynamic Cell Reprogramming with Nanosensors. (academictree.org)
  • function
  • Of note, these effects of PTHrP overexpression on cell growth and function were similarly decreased in the ΔSP mutant after PTH1R small interfering RNA transfection or by a PTH1R antagonist. (sigmaaldrich.com)
  • Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinases. (springer.com)
  • assembly
  • Merkl PE & Knipe DM Role for a Filamentous Nuclear Assembly of IFI16, DNA, and Host Factors in Restriction of Herpesviral Infection. (abcam.com)
  • expression
  • Our results indicate that high nuclear STAT3 expression levels by automated quantitative analysis are associated with favorable outcome in HNSCC. (nih.gov)
  • Programmed cell death-ligand 1 expression and efficacy of cisplatin-based chemotherapy in lung cancer: A sub-analysis of data from the two Okayama Lung Cancer Study Group prospective feasibility studies. (nih.gov)
  • export
  • Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis. (icr.ac.uk)
  • MAPK
  • Xiao C, Zhong L, Shan Z, Xu T, Gan L, Song H, Yang R, Li L, Liu B. NLS-RARα Inhibits the Effects of All-trans Retinoic Acid on NB4 Cells by Interacting with P38α MAPK. (medsci.org)
  • transient
  • Laser irradiation of the cells heats the nanoparticles to high temperatures resulting in vapourisation of the water-based cytosol, and the transient formation of nanobubbles. (rsc.org)