Energy MetabolismGlycolysisLipid MetabolismGlucoseMetabolic Networks and PathwaysCellsModels, BiologicalLactic AcidCitric Acid CycleAdenosine TriphosphateMitochondriaOxidative PhosphorylationLiverSignal TransductionOxidation-ReductionCells, CulturedNeoplasmsCellular StructuresMetabolismMetabolomicsCarbonOxygen Consumption2,3-DiphosphoglyceratePyruvate KinaseMycoplasma hyorhinisCell SurvivalKineticsPyruvic AcidFatty AcidsGene Expression ProfilingCell ProliferationEnzymesCell Line, TumorLactatesGlutamineOxygenCell RespirationDiphosphoglyceric AcidsHomeostasisInsulinCell LineTOR Serine-Threonine KinasesGene Expression RegulationNADPOxidative StressCarbon IsotopesTime FactorsAutophagyCell HypoxiaBiological TransportAMP-Activated Protein KinasesReactive Oxygen SpeciesHypoxia-Inducible Factor 1, alpha SubunitRNA, MessengerInsulin-Secreting CellsBiotransformationDeoxyglucoseMagnetic Resonance SpectroscopyProteomicsMutationOligonucleotide Array Sequence AnalysisCulture MediaMitochondrial ProteinsMicrosomes, LiverCytochrome P-450 Enzyme SystemErythrocytesHydrogen-Ion ConcentrationMolecular Sequence DataDose-Response Relationship, DrugStress, PhysiologicalNADApoptosisProteomeSuccinate DehydrogenaseMice, Inbred C57BLTranscription, GeneticMass SpectrometryCalciumPotassium Channels, Inwardly RectifyingBrainMice, KnockoutSulfonylurea ReceptorsMetabolism, Inborn ErrorsElectrophoresis, Gel, Two-DimensionalL-Lactate DehydrogenaseCell MembraneChromatography, High Pressure LiquidBlotting, WesternReverse Transcriptase Polymerase Chain ReactionHEK293 CellsFibroblastsEnzyme InhibitorsGene ExpressionUp-RegulationPhenotypeProtein BiosynthesisBacterial ProteinsCarbon RadioisotopesCarrier ProteinsRNA