• Electron microscopy reveals loss of desmosomes (epithelial intercellular junctions formed by membrane and submembrane protein complexes), breakdown of desmosome-keratin intermediate filament attachment, and perinuclear aggregates of keratin intermediate filaments. (medscape.com)
  • Even though its sequence along with its expressional pattern in cancer cell lines are evident, the functional aspects concerning cell proliferation, viability, differentiation and cell cycle regulation of NDRG1 remains vague. (scirp.org)
  • Unpredictably, cell cycle progression, cell proliferation and DNA synthesis were unaffected fol lowing NDRG1 expression. (scirp.org)
  • T. Napso, N. Azzam, A. Lerner and F. Fares, " N-myc Downstream Regulated Gene 1 Increases Differentiation Factors Level in Human Prostate Cancer Cells without Affecting Cell Proliferation and Cell Cycle Profiles," Journal of Cancer Therapy , Vol. 4 No. 2, 2013, pp. 568-574. (scirp.org)
  • Overexpression of this gene is associated with tumor cell proliferation and metastasis. (cancerindex.org)
  • Transwell migration, cell cycle analysis, MTT and colony formation assays were performed to determine the effect of DRAM2 overexpression and knockdown on NSCLC-cell migration and proliferation. (cancerindex.org)
  • Additionally, DRAM2 overexpression promoted cell metastasis and proliferation in vitro, while knockdown of DRAM2 expression yielded opposite result. (cancerindex.org)
  • The present work introduces a computational implementation of some principles of a theory of organism development, namely that the default state of cells is proliferation and motility, and includes the principle of variation and organization by closure of constraints. (nature.com)
  • In the present model, the bioelectric context of cells and tissue is the field responsible for organization, as it regulates cell proliferation and the level of communication driving the system's evolution. (nature.com)
  • Starting from a depolarized (proliferative) cell, the organism grows to a certain size, limited by the increasingly polarized state after successive proliferation events. (nature.com)
  • Previous researches completed by our team have also demonstrated that resveratrol inhibits the proliferation, invasion, and metastasis of colorectal cancer cells [ 5 ]. (hindawi.com)
  • This suggests a common cell proliferation defect in cartilage-hair hypoplasia. (medscape.com)
  • Our previous work showed that upon the alteration of the blood-retina barrier, the serine protease thrombin could contribute to the transformation, proliferation, and migration of RPE cells. (molvis.org)
  • Long noncoding RNAs (lncRNAs) regulate a number of physiological and pathological processes, including gene transcription and translation, chromatin modification, cell cycle progression, cell proliferation, and oncogenic and tumor-suppressive signals in cancer 6 . (researchsquare.com)
  • Combining the six-axis robot-based bioprinter and oil-bath-based cell printing system, the researchers achieved a full range of cell printing on a complex-shaped blood vessel scaffold without causing cell damage or compromising cell proliferation and function. (nanowerk.com)
  • In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (cdc.gov)
  • Carcinogenesis is introduced through a localized event (a spot of depolarized cells) or by random depolarization of cells in the tissue, which returns cells to their initial proliferative state. (nature.com)
  • This simplified model of embryogenesis, tissue organization and carcinogenesis, based on non-excitable cells' bioelectric properties, can be made more realistic with the introduction of other components, like biochemical fields and mechanical interactions, which are fundamental for a more faithful representation of reality. (nature.com)
  • An organism's growth and transformation during its life cycle is a tremendously complex succession of processes and events but even a simplistic and limited theory, dealing with only the general trend and generating a broad vision of tissue organization, can drive specific studies and experiments to further inform this field of research. (nature.com)
  • Similar to normal tissue stem cells, cancer stem cells (CSCs) are thought to be quiescent or slow-cycling and, thereby, insensitive to chemo- and radiotherapies. (elsevierpure.com)
  • To study cell and tissue dynamics we develop new technologies to measure physical forces at the cell-cell and cell-matrix interface. (ibecbarcelona.eu)
  • By combining these technologies with computational analysis of cell shape and velocity we obtain a full experimental characterization of epithelial dynamics during tissue growth, wound healing and cancer cell invasion. (ibecbarcelona.eu)
  • Surprisingly, some cells in the tissue barely stretch, while others become 'superstretched', increasing their area more than ten times. (ibecbarcelona.eu)
  • 3D bioprinting, which combines a 3D printer with bioinks (often containing cells and biomaterials) to fabricate tissue/organ-mimicking structures, is one of the most promising technologies for in vitro human organ generation. (nanowerk.com)
  • In this study ( Bioactive Materials , 'A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication' ), the researchers creatively converted a six-axis robotic arm into a 3D bio-printer, enabling cell printing from all directions. (nanowerk.com)
  • In theory, repeating such print-and-culture cycle could generate complex tissue/organs with printed cells interlaced and connected with blood vessel networks to maintain long-term survival and functions. (nanowerk.com)
  • By printing the mixture of endothelial cells and cardiomyocytes, researchers generated a piece of vascularized cardiac tissue, which maintained rhythmic beating and alive for at least 6 months. (nanowerk.com)
  • WD-repeat proteins are a large family found in all eukaryotes and are implicated in a variety of functions ranging from signal transduction and transcription regulation to cell cycle control and apoptosis. (embl.de)
  • Biochemical and molecular aspects of cellular function, interactions and communication including cell cycle, apoptosis, cancer, neuronal transmission and the signal transduction pathways that integrate them. (sfu.ca)
  • In a different study, in which researchers systematically analyzed mutations identical to those found in patients with Darier disease, mutant SERCA2 protein aggregates were found to cause stress to the endoplasmic reticulum, subsequently inducing cell apoptosis. (medscape.com)
  • Tight junctions (TJs) located at the apical lateral region of adjacent intestinal epithelial cells are largely responsible for regulating the intestinal mucosal barrier. (ecco-ibd.eu)
  • Gene ontology annotation revealed a number of critical signalling pathways that were differentially expressed in cells treated with LA, including biological processes involved in establishment of cell polarity, molecular functions that regulate junctional structures, and cellular components associated with epithelial repair (cell leading edge, ruffle and apical junctional complex). (ecco-ibd.eu)
  • The apical face of each seam cell faces the cuticle and remains in contact with the cuticle along the full length of the cell (a, b). (wormatlas.org)
  • In response to DNA damage, a synthetic lethal relationship exists between the cell cycle checkpoint kinase MK2 and the tumor suppressor p53. (nature.com)
  • Because BRCA mutations are observed in fewer than 10% of cancer patients (cBioPortal: 6.7%) 11 , 12 , 13 the identification of additional genes that share synthetic lethal sensitivity relationships with mutated oncogenes or tumor suppressors would greatly enhance the implementation of tumor cell-specific synthetic lethal sensitivity to improve an anticancer therapeutic response. (nature.com)
  • Because most tumors are deficient in one or more aspects of the function of the p53 tumor suppressor, either as a consequence of mutations within p53, or impairment of upstream and downstream modulators of p53 activity 19 , targeting MK2 has the potential to selectively enhance tumor cell killing without increasing the genotoxic effects of chemotherapy on normal p53-wild type tissues. (nature.com)
  • In addition to basic science investigations in such areas as tumor cell invasion, oncogenes, immunotherapy and genetic inheritance, our scientists and physicians participate in national cancer trials. (upstate.edu)
  • Furthermore, each expanded CD44 + gland in gastric tumor of K19-Wnt1/C2mE mouse contains a few BrdU label-retaining quiescent or slow-cycling cells, suggesting that the CD44 + SCJ cells in normal mouse are candidates for the cell-of-origin of gastric CSCs. (elsevierpure.com)
  • Both processes are the result of a complex interaction between tumor cells and their microenvironment. (ibecbarcelona.eu)
  • CD44, a cell surface component that interacts with the extracellular matrix, has been found to be highly expressed in CSCs of several solid tumors. (elsevierpure.com)
  • When one connexon on a cell membrane encounters another connexon on the adjacent cell, they create a complete continuous channel that can open and close. (jove.com)
  • Similarly, in plants, the rigid walls of adjacent cells are connected via membrane-lined channels called plasmodesmata. (jove.com)
  • In animal cells, gap junctions are formed when a set of six proteins called connexins arrange themselves to form a cylindrical structure within the plasma membrane. (jove.com)
  • However, the pathway downstream NDRG1, involving p21 and c8/18, regulating cell cycle progression and DNA synthesis is unfunctional. (scirp.org)
  • These results revealed that NDRG1 is functional in prostate cancer cells and able to induce expression of differentiation factors through p53 independent pathway. (scirp.org)
  • A Novel Gene Which Is Up-Regulated during Colon Epithelial Cell Differentiation and Down-Regulated in Colorectal Neoplasms," Laboratory Investigation: A Journal of Technical Methods and Pathology, Vol. 77, No. 1, 1997, pp. 85-92. (scirp.org)
  • DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. (cipsm.de)
  • The adult alae are commonly used as an indicator of hypodermal seam cell terminal differentiation. (wormatlas.org)
  • Microarray analyses detected a suite of master developmental regulators that control differentiation and maintenance of diverse cell lineages. (biomedcentral.com)
  • Molecular Biology of the Cell , 7th edition. (sfu.ca)
  • Directed cell migration is one of the earliest observations in cell biology, dating back to the late XIX century. (ibecbarcelona.eu)
  • After mitosis, daughter cells can either remain proliferative and re-enter the cell cycle or become terminally postmitotic and migrate out of the VZ ( McConnell, 1995 ). (jneurosci.org)
  • Human embryonic stem cells (hESc) can also be used to analyze the in vitro development from undifferentiated pluripotent cells leading to terminally differentiated cell types, recapitulating the process of early embryonic development [5] . (plos.org)
  • For example, increased expression of LINC00958 attributes to cell metastasis in gastric cancer 7 . (researchsquare.com)
  • Cancer cell invasion and metastasis remain the leading cause of death in patients with cancer. (ibecbarcelona.eu)
  • iCLIP of spliceosome components reveals that PRPF8 depletion decreases RNP complex formation at most splice sites in exon-intron junctions throughout the genome. (biomedcentral.com)
  • The oocyte is loaded with maternal mRNAs and proteins that control the cell maintenance and fate and the formation of the body plan prior to the onset of zygotic genome expression [ 3 , 4 ]. (biomedcentral.com)
  • DRAM2 overexpression also increased proteins CDK4, CyclinD3, and decreased p27 expression, all of which are cell cycle-related factors. (cancerindex.org)
  • Gap junctions are composed of transmembrane connexin proteins. (jove.com)
  • In the central nervous system, synapses form when specific organelles and proteins are recruited to a site where the axon of one cell contacts a dendrite of another. (rupress.org)
  • Transcripts found in unfertilized oocytes also encoded a large number of proteins implicated in cell adherence, tight junction and focal adhesion, suggesting high complexity in terms of structure and cellular interactions in embryos prior to midblastula transition (MBT). (biomedcentral.com)
  • The selectivity of gap junctions allows a single cell to regulate communication with its neighbors and coordinate a complex multicellular response. (jove.com)
  • Organoids from many organs have now been obtained from embryonic stem cells, induced pluripotent stem cells and organ progenitors. (ibecbarcelona.eu)
  • K. Kokame, H. Kato and T. Miyata, "Homocysteine-Respondent Genes in Vascular Endothelial Cells Identified by Differential Display Analysis. (scirp.org)
  • C. Two-robot cooperation platform (left) can simultaneously print different types of cells onto complex-shaped vascular scaffold (middle) to form patterned cell organization (right). (nanowerk.com)
  • In summary, compared with conventional methods, the novel 3D bioprinting system reported in this study offers a new strategy to print cells on complex-shaped vascular scaffolds and facilitate angiogenesis among post-printed cells, therefore enables long-term cell survival and demonstrates a feasible way to generate large-scale and functional artificial tissues/organs in vitro. (nanowerk.com)
  • Gap junctions in vascular tissues. (forex-consultant.com)
  • As shown by examination of semi-thin and ultrathin sections, cell surface occupied by the basal ES connecting neighboring Sertoli cells and the number of gap and tight junctions coexisting with the basal ES were apparently reduced in flutamide-treated rats. (biomedcentral.com)
  • This study explores the use of a simple human neurosphere-based in vitro model to characterise the pharmacological and toxicological effects of LiCl and VPA using gene expression changes linked to phenotypic alterations in cells. (plos.org)
  • These results demonstrate distinct patterns of spontaneous [Ca 2+ ] i change in cortical precursor cells and raise the possibility that these dynamics may contribute to the regulation of neurogenesis. (jneurosci.org)
  • This theory would deal with the way an organism spontaneously grows from a single cell to a complete and complex organism, introducing organization at the different development stages and homeostasis for a mature organism. (nature.com)
  • For example, the gap junctions in cardiac muscles control the flow of ions in a rhythmic manner. (jove.com)
  • SL originally described a relationship between two genes, where alteration of either gene alone results in viable cells, but alteration (mutation, loss, or inhibition) of both genes simultaneously was lethal. (nature.com)
  • Numerous genes transcribed in oocytes are involved in multiple aspects of cell maintenance and protection, including metabolism, signal perception and transduction, RNA processing, cell cycle, defense against pathogens and DNA damage. (biomedcentral.com)
  • Modulation of intracellular free calcium concentration ([Ca 2+ ] i ) may be part of the signaling pathway by which both local environmental factors and cell autonomous developmental programs influence corticogenesis. (jneurosci.org)
  • But how do the cells coordinate the extracellular formation of a contact with the intracellular movement of organelles? (rupress.org)
  • describe the interaction of neural cell adhesion molecule (NCAM) clusters with intracellular organelle aggregates derived from the trans-Golgi network (TGN). (rupress.org)
  • NEUROBIOTIN is an amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons and some have fluorophores conjugated enabling direct visualisation as well as an alternative label via the biotin. (2bscientific.com)
  • The three germ layers and the body plan of the mature organism are established during gastrulation, and the period is characterized by extensive cell movements and intracellular communications [ 21 , 22 ]. (biomedcentral.com)
  • In some tissues, cell junctions, such as gap junctions act as contact points between neighboring cells and facilitate contact-dependent signaling. (jove.com)
  • In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants. (jove.com)
  • But these treatments, to some extent, easily produce side effects on normal cells, organs, and other tissues of the human body, thus accelerating the death process of cancer patients. (hindawi.com)
  • We develop new technologies to map and perturb the main physical properties that determine how cells and tissues grow, move, invade and remodel. (ibecbarcelona.eu)
  • Preexisting antivector immunity can severely compromise the ability of Salmonella enterica serovar Typhimurium live vaccines to induce protective CD8 T-cell frequencies after type III secretion system-mediated heterologous protein translocation in orally immunized mice. (cipsm.de)
  • Furthermore, inspired by the natural organ developmental process, the team designed a repeated print-and-culture bioprinting strategy: after printing mono- or multi-layers of cells on the blood vessel scaffold, the printed cells would be cultured for certain intervals to induce the formation of cell-cell contact and new blood vessels, then the scaffold and already printed cells were subjected to a new round of bioprinting. (nanowerk.com)
  • MJ solar cell technology provides a direct replacement for lower efficiency single-junction cells. (spacefoundation.org)
  • The dynamical photoresponse of a bulk heterojunction solar cell based on PTB7 and PC 71 BM is subsequently investigated by recording point-spectroscopy curves as a function of the optical power at the cathode and by mapping 2D time-resolved images of the surface photovoltage of the bare organic active layer. (beilstein-journals.org)
  • Whatever material used, improving the performance of the solar cell requires a precise understanding of the relationship of the structural, chemical and optoelectronic properties of the device. (beilstein-journals.org)
  • By doing away with silicon wafers, the Ampuse model will have the potential to produce a 15%-efficient solar cell at less than 50 cents per watt. (scitechdaily.com)
  • Think of it as the Rube Goldberg approach to creating a solar cell. (scitechdaily.com)
  • However, the commonly used 3D bioprinting approach is unable to incorporate blood vessel networks during the bioprinting process, therefore facing difficulties in fabricating functional and long-lived complex organs due to the lack of nutrient supply to printed cells. (nanowerk.com)
  • Although spontaneous changes of [Ca 2+ ] i have been examined in immature cortical neurons, the calcium dynamics of cortical precursor cells have received less attention. (jneurosci.org)
  • Immunohistochemical staining confirmed that these events occurred primarily in precursor cells rather than in postmitotic neurons. (jneurosci.org)
  • Whilst LiCl exposure did not significantly alter the proportion of cells expressing markers for stem cells/undifferentiated cells (Oct4, SSEA4), neurons (Neurofilament M), astrocytes (GFAP) or cell cycle phase, the drug caused a 1.4-fold increase in total cell number. (plos.org)
  • Therefore, compared to normal p53-proficient cells, p53-defective cells are more reliant on MK2 activity, which drives an alternative cell cycle checkpoint pathway that stabilizes the CKI inhibitors p27 Kip1 and Gadd45α in order to maintain G 1 /S and G 2 /M arrest after certain types of DNA damage 16 , 18 . (nature.com)
  • The KEGG and GO analyses indicated 'Human T − cell leukemia virus 1 infection' and 'Hippo signaling pathway' were the main affected biological processes. (researchsquare.com)
  • Each plasmodesma allows the transport of molecules between cells through the connected cytoplasm as well as through a desmotubule, the tubular continuation of the smooth endoplasmic reticulum. (jove.com)
  • RMRP is required for cell growth, consistent with observations that a generalized defect in cell growth is observed in T cells, B cells, and fibroblasts. (medscape.com)
  • We focus on the interaction between epithelial cancer cells and Cancer Associated Fibroblasts (CAFs), the most abundant cell type in the tumour stroma. (ibecbarcelona.eu)
  • This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. (jove.com)
  • When imaging near the ventricular surface, synchronous spontaneous [Ca 2+ ] i increases were frequently observed in pairs of adjacent cells. (jneurosci.org)
  • Gap junctions are specialized protein channels that connect the cytoplasms of adjacent cells. (jove.com)
  • When connexons of adjacent animal cells align, a channel forms between the two cells. (jove.com)
  • In order to continue to improve the environmental performance of PV manufacturing using proposed industrial symbiosis techniques, this paper performs a life cycle analysis (LCA) on both conventional 1-GW scaled a-Si:H-based single junction and a-Si:H/microcrystalline-Si:H tandem cell solar PV manufacturing plants and such plants coupled to silane recycling plants. (appropedia.org)
  • Using a recycling process that results in a silane loss of only 17% instead of conventional processing that loses 85% silane, results in an energy savings of 81,700 GJ and prevents 4400 tons of CO 2 from being released into the atmosphere per year for the single junction plant. (appropedia.org)
  • The stimulation for these contractions likely originates in modified smooth muscle cells called interstitial cells of Cajal. (wikipedia.org)
  • In the interstitial compartment, however, short-term exposure leads to both histological and functional changes of the Leydig cells. (biomedcentral.com)
  • To further identify the potential signaling pathways after the knockdown of LINC00958 in Ishikawa cells, we performed the KEGG and GO analyses (Figure 2). (researchsquare.com)
  • Occurring between meals, the migrating motor complex is a series of peristaltic wave cycles in distinct phases starting with relaxation, followed by an increasing level of activity to a peak level of peristaltic activity lasting for 5-15 minutes. (wikipedia.org)
  • During this time, precursor cells undergo interkinetic nuclear migration ( Seymour and Berry, 1975 ) in which cells in the DNA synthetic S phase have their nuclei in the upper third of the VZ. (jneurosci.org)
  • Also known as taxis, directed cell migration has been commonly associated with chemotaxis, i.e. the ability of a broad variety of cell types to migrate following gradients of chemical factors. (ibecbarcelona.eu)
  • This new migration mode emerges only in cell collectives and, strikingly, does not require isolated cells to exhibit gradient sensing. (ibecbarcelona.eu)
  • Immunoreceptor signaling during development, homeostasis, and effector function of T cells and NK cells. (upstate.edu)
  • Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). (cancerindex.org)
  • Larazotide acetate (LA, Innovate Biopharmaceuticals, Inc., Raleigh, NC) is a synthetic, eight amino acid peptide that is known to act as a TJ regulator capable of closing 'leaky' interepithelial junctions. (ecco-ibd.eu)
  • Glial cells are primarily produced in a second germinal zone, the subventricular zone that is located superficially to the VZ. (jneurosci.org)
  • Glial cell production increases as neurogenesis declines, peaking during the early postnatal period ( Bayer and Altman, 1991 ). (jneurosci.org)
  • Contact-dependent signaling requires the establishment of a direct contact between cells for communication. (jove.com)
  • Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. (jove.com)
  • Here we show that a gastric gland residing at the squamo-columnar junction (SCJ) in normal mouse stomach contains CD44 + stem cell-like slow-cycling cells and that this characteristic CD44 + gland was expanded by prostaglandin E2 (PGE 2 ) and Wnt signaling in K19-Wnt1/C2mE mouse, a genetic mouse model for gastric tumorigenesis. (elsevierpure.com)
  • The analysis of three transgenic mouse lines, K19-Wnt1, K19-C2mE and K19-Wnt1/C2mE, revealed that the expansion of CD44 + SCJ cells is triggered by PGE 2 -mediated signaling and is prominently enhanced by the addition of Wnt activation. (elsevierpure.com)
  • These observations suggest that PGE 2 -mediated inflammatory signaling and Wnt signaling cooperatively trigger the expansion of CD44 + slow-cycling stem-like cells in SCJ, leading to development of lethal gastric tumors in mice. (elsevierpure.com)
  • Furthermore, human cDNA of NDRG1 from normal placenta was cloned into a eukaryotic expression vector and transfected into the three cancer cell lines. (scirp.org)
  • This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. (cancerindex.org)
  • In addition, in order to phenotypically anchor the gene expression data, changes in the heterogeneity of cell subtype populations and cell cycle phase were monitored using flow cytometry. (plos.org)
  • Loss of sensitivity to p21 cell cycle control may be associated with prostatic cancer behavior. (scirp.org)
  • DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53. (cancerindex.org)
  • These findings establish a mechanism for co-targeting DNA damage-induced cell cycle checkpoints in combination with repair of cisplatin-DNA lesions in vivo using RNAi nanocarriers, and motivate further exploration of ASL as a generalized strategy to improve cancer treatment. (nature.com)
  • Cancer cells that are defective in p53 function are deficient in their ability to transcriptionally upregulate the CDK inhibitor p21 after genotoxic stress. (nature.com)
  • Tyrosine kinase inhibitors (TKIs) against the human epidermal growth factor receptor (EGFR) are now standard treatment in the clinic for patients with advanced EGFR mutant non-small-cell lung cancer (NSCLC). (researchgate.net)
  • In our study, we analyzed the effects of the knockdown of LINC00958 in endometrial cancer cells by using the RNA-seq data. (researchsquare.com)
  • T lymphocytes for adoptive cell therapy against hematological cancer. (upstate.edu)
  • One of our main lines of research is to study how tumours exploit the functions of non-cancer cells in their microenvironment to invade and metastasize. (ibecbarcelona.eu)
  • Breast cancer cells attached to a surface rich in collagen. (ibecbarcelona.eu)
  • Of particular interest is their contribution to Developmental Neurotoxicity (DNT) as well as their potential impact on stem cells. (plos.org)
  • When cells pass from S to G 2 , the nuclei migrate toward the VZ surface where mitosis occurs. (jneurosci.org)
  • We analyzed the molecular mechanisms leading to glutamate release from rat primary cultures of RPE cells, under isosmotic conditions. (molvis.org)
  • Present study was designed to establish a causal connection between changes in the cell-cell junction protein expression at the blood-testis barrier and alterations in the adult rat testis histology following an anti-androgen flutamide exposure. (biomedcentral.com)
  • The investigators found that the resultant transfected cells showed defects in ATP2A2 protein expression (15 mutants), ATP hydrolysis (29 mutants), calcium transport (4 mutants), and calcium binding and kinetics (3 mutants). (medscape.com)
  • We have developed optogenetic tools based on controlling the activity of endogenous RhoA to upregulate or downregulate cell contractility and to control cell shape and mechanotransduction. (ibecbarcelona.eu)
  • These junctions allow selective small ions and water-soluble molecules to pass through but exclude macromolecules like large peptides. (jove.com)
  • At a developing contact site, the NCAM molecules of the two cells cluster, trapping the TGN organelles and stabilizing the nascent synapse. (rupress.org)
  • These cells are also sometimes referred to as lateral hypodermal cells, because they share some functions with the major hypodermis, including secreting cuticle and generating the contractile force during elongation of the embryo. (wormatlas.org)
  • A. Schematic view of left lateral seam cells in an L1-stage larva. (wormatlas.org)
  • B. Schematic view of left lateral seam cells in adult hermaphrodite. (wormatlas.org)
  • HSV1 infects a broad range of cells and shows fast trans-neuronal spread in the central nervous system and can lead to meningitis or encephalitis. (2bscientific.com)
  • B cells are therefore particularly dependent on 'quality control' mechanisms to oversee antibody production. (cipsm.de)
  • TradeRoute from Rice Lake Weighing Systems is designed to install around the frame of many common straight-truck designs using a combination of frame-hugging weigh modules, a stainless steel junction box, and a weatherproof control center that houses Rice Lake's 920i Indicator/Controller and Epson TM-U295 Ticket Printer. (ccjdigital.com)
  • The manufacturer said the new product is based on tunnel oxide passivated contact (TOPCon) cells, M10 wafers and high-performance hybrid passivity (HPDC) dual junction technology. (pv-magazine.com)
  • Hi-MO 7 effectively ensures its reliability throughout its life cycle with optimized designs such as high-quality monocrystalline silicon wafers, customized cell paste, optimized module encapsulation film system, SMBB high-precision interconnection, and high-reliability automatic welding of junction boxes," the manufacturer stated. (pv-magazine.com)
  • Its disadvantage is that purifying it into wafers suitable for solar cells is expensive and energy intensive. (scitechdaily.com)