• this approach has been championed as an answer to the many issues concerning embryonic stem cells (ESCs) and the destruction of viable embryos for medical use, though questions remain on how homologous the two cell types truly are. (wikipedia.org)
  • Controversy surrounds human ESC work due to the destruction of viable human embryos, leading scientists to seek alternative methods of obtaining pluripotent stem cells, SCNT is one such method. (wikipedia.org)
  • To facilitate discussion, it was agreed to distinguish between human cloning for reproductive purposes, that is to produce a human individual, and human cloning for nonreproductive purposes, that is to produce embryos for basic and applied research. (who.int)
  • Some countries have proposed a total ban on any research involving the cloning of human embryos. (who.int)
  • Several participants reported interest among the scientific and medical communities of their countries and regions in the use of somatic cell nuclear transfer techniques to produce cloned human embryos for time-limited basic research on ageing and genetic diseases. (who.int)
  • The Catholic Church has always held that stem-cell research and therapies are morally acceptable, as long as they don't involve the creation and destruction of human embryos. (archstl.org)
  • Citizens disagree about whether we should destroy human embryos for their stem cells-and if so, which embryos, with whose money, under what regulatory guidelines. (eppc.org)
  • The holy grail of regenerative medicine-whatever one's ethical beliefs about destroying embryos-is to "reprogram" regular cells from one's own body so that individuals can be the source of their own rejection-proof therapies. (eppc.org)
  • That is to say, we risk turning developed cells into developing embryos, and thus risk engaging in the very activities of embryo destruction and human cloning that we seek to avoid. (eppc.org)
  • Far more controversial-and for good reason-are stem cells derived from destroyed human embryos. (eppc.org)
  • And now Washington joins the infamous list with Senate Bill 5594, a thoroughly disingenuous piece of legislation that purports to outlaw the cloning of human beings, but by manipulating language and redefining terms, actually permits human cloning and gestation of the resulting cloned embryos through the ninth month. (cbc-network.org)
  • The use of embryonic stem cells has been a source of considerable controversy due to its sacrifice of human embryos in the blastocyst stage, which some people view as the destruction of human life . (citizendium.org)
  • Human embryos fertilized in the ordinary manner and harvested in the blastocyst stage have been used as an extensive source of stem cells for research purposes, and have been shown to possess therapeutic value in laboratory animals. (citizendium.org)
  • The most infamous study of embryonic stem cells asserted that cloned human embryos had been created via somatic cell nuclear transfer, and stem cells had been generated from these embryos. (citizendium.org)
  • Ethical objections to the use of human embryonic stem cells revolve around the destruction of human embryos in the blastocyst stage to obtain the stem cells. (citizendium.org)
  • Animals (or embryos) composed of cells of different genetic origin. (nationalacademies.org)
  • Cell lines derived from early embryos that have the potential to differentiate into all types of somatic cells as well as to form germ line cells, and hence whole animals, when injected into early embryos. (nationalacademies.org)
  • I've been working with mammalian embryos for over 40 years, with some work in my lab specifically focusing on various methods of cloning cattle and other livestock species. (wptv.com)
  • Sometimes the process of cloning by somatic cell nuclear transfer still produces abnormal embryos, most of which die. (wptv.com)
  • The removal and re-introduction of the nucleus, the electric stimulation of the cell, and the in vitro fertilization all combine to make viable embryos in only about 1 in 200 attempts. (humansfuture.org)
  • In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
  • They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
  • The somatic cell and the oocyte is then fused (f) and the embryos is allowed to develop to a blastocyst in vitro (g). (biomedcentral.com)
  • Currently, the efficiency for nuclear transfer is between 0-10%, i.e., 0-10 live births after transfer of 100 cloned embryos. (biomedcentral.com)
  • Outline example of cloning animal embryos via natural and artificial embryo splitting. (biologyforlife.com)
  • 3.5.A4 Production of clones embryos produced by somatic-cell nuclear transfer. (biologyforlife.com)
  • Outline the production of embryos via somatic cell nuclear transfer. (biologyforlife.com)
  • Stem cells may be derived from adult tissues but the most potent are extracted from developing human embryos. (edu.au)
  • First, while stem-cell experimentation could involve the creation of embryos with the express purpose of destroying them, this is not the only means available for obtaining embryos. (jewishvaluesonline.org)
  • Thus, there is broad halakhic (Jewish legal) agreement that stem cell research is permitted on "excess" embryos. (jewishvaluesonline.org)
  • Most (but not all) authorities would forbid the creation of embryos with the express purpose of killing them in the pursuit of stem cell research. (jewishvaluesonline.org)
  • The controversy over stem cell research is focused specifically on the use of stem cells taken from embryos. (jewishvaluesonline.org)
  • Our study established the optimal TSA treatment on porcine donor cells and cloned embryos, 250 nmol/L, 24 h and 40 nmol/L, 24 h, respectively. (chinagene.cn)
  • Aberrant methylation of donor genome in cloned bovine embryos. (chinagene.cn)
  • Precise recapitulation of methylation change in early cloned embryos. (chinagene.cn)
  • It is used in both therapeutic and reproductive cloning. (wikipedia.org)
  • In 1996, Dolly the sheep became famous for being the first successful case of the reproductive cloning of a mammal. (wikipedia.org)
  • Stem cells can then be obtained by the destruction of this clone embryo for use in therapeutic cloning or in the case of reproductive cloning the clone embryo is implanted into a host mother for further development and brought to term. (wikipedia.org)
  • Since the term "born" has been used as an essential part of the definition of " reproductive cloning " used by Weissman, the National Academy of Sciences, etc., then it is critical to use the accurate term with the proper meaning. (lifeissues.net)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
  • In most countries, it is illegal to attempt reproductive cloning in humans. (eurostemcell.org)
  • Summary information is provided here on the outcome of the meetings held during the last three months of 1997, in which the ethical, scientific and social implications of cloning were discussed in relation to the potential biomedical applications of this technique in such areas of human health as reproductive health, xenotransplantation and medical genetics. (who.int)
  • Other regions reported that some individuals and religious leaders might consider reproductive cloning acceptable in certain cases such as otherwise untreatable infertility, or to avoid inherited genetic diseases. (who.int)
  • But what is not getting such wide reporting is the use of pluripotent stem cells (as well as many other types of cells and genetic engineering techniques) for reproductive purposes . (lifeissues.net)
  • 3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
  • In order to better appreciate the role of stem cell research in reproductive medicine, there is a need to understand the critical biological principles of stem cell research and its potential applications to medicine. (jcpa.org)
  • While there is a great deal published on the potential medical applications of stem cell research to treat or cure diseases such as diabetes, Alzheimer's disease, Parkinson's disease, cancer, and heart disease, much less has been published on the future impact of stem cell research in reproductive medicine. (jcpa.org)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • If it is to be brought to birth, the process is usually called "reproductive cloning. (cbc-network.org)
  • Dolly's creation triggered fears of human reproductive cloning, or producing genetic copies of living or dead people, but mainstream scientists have ruled this out as far too dangerous. (cyprus-mail.com)
  • … "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
  • Describe the process of reproductive cloning via embryo splitting. (biologyforlife.com)
  • Describe the process of reproductive cloning via somatic cell nuclear transfer. (biologyforlife.com)
  • Compare therapeutic cloning to reproductive cloning. (biologyforlife.com)
  • and the general public debate about reproductive cloning. (edu.au)
  • In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
  • Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
  • To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
  • In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
  • But adult stem cells also raise some interesting ethical dilemmas alongside their great therapeutic promise. (eppc.org)
  • If the cloned human organism is to be experimented upon and destroyed, the process is often called "therapeutic cloning. (cbc-network.org)
  • The use of the pluripotent and/or self-renewing qualities of stem cells is believed to have therapeutic benefits for the regeneration of tissue in humans. (citizendium.org)
  • The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
  • Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
  • This paper's main objective is to support the argument that embryo's cloning for one's self to serve as the stem cells' source for purposes of therapy should be considered morally permissible for people who want to prolong lives via this type of therapeutic option . (premiumessays.net)
  • As such, when a person opts to clone their embryo in order to produce stem cells that can be used for therapeutic purposes that will prolong life, they violate one of these moral principles which entail protecting human life as a duty. (premiumessays.net)
  • Development will ensue normally and after many mitotic divisions, the single cell forms a blastocyst (an early stage embryo with about 100 cells) with an identical genome to the original organism (i.e. a clone). (wikipedia.org)
  • These cells genetically matched the donor organism from which they came. (wikipedia.org)
  • These cells are deemed to have a pluripotent potential because they have the ability to give rise to all of the tissues found in an adult organism. (wikipedia.org)
  • These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
  • Stem cell research is, in part, a quest to understand cellular differentiation, the process by which a human being develops from one fertilized cell into a multicellular organism composed of over 200 different cell types - for example muscle, nerve, blood cell, or kidney. (jcpa.org)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • At that point - and this is important to understand - there is no more cloning to be done since a new human organism now exists. (cbc-network.org)
  • If the authors of this bill really meant what they appear to have written, their legislation would ban all human cloning, since as we have seen, biologically, a new human organism, that is, a new human being, comes into existence with the completion of SCNT. (cbc-network.org)
  • Or to put it the other way around, cloning, not implantation, is what produces a new and distinct human organism. (cbc-network.org)
  • XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
  • … "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
  • Cloning, Organism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • This graph shows the total number of publications written about "Cloning, Organism" by people in this website by year, and whether "Cloning, Organism" was a major or minor topic of these publications. (childrensmercy.org)
  • Below are the most recent publications written about "Cloning, Organism" by people in Profiles. (childrensmercy.org)
  • Cloning is the process of creating a genetically identical duplicate of an organism. (humansfuture.org)
  • SCNT refers to a process that entails transferring somatic cells of an existing organism into the oocyte where the nucleus came from (National Human Genome Research Institute Para 1). (premiumessays.net)
  • Viruses do their damage by entering the cells of the host organism and then using the cellular machinery to replicate themselves, often killing the host cells in the process. (khanneasuntzu.com)
  • We showed that COG4 knockout led to a decrease of extracellular HS that specifically affected dsRNA transfection efficiency and reduced viral production, which explains the increased cell survival of these mutants.IMPORTANCE When facing a viral infection, the organism has to put in place a number of defense mechanisms in order to clear the pathogen from the cell. (cnrs.fr)
  • In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. (wikipedia.org)
  • For example, if a person with Parkinson's disease donated their somatic cells, the stem cells resulting from SCNT would have genes that contribute to Parkinson's disease. (wikipedia.org)
  • Another application of SCNT stem cell research is using the patient specific stem cell lines to generate tissues or even organs for transplant into the specific patient. (wikipedia.org)
  • Only a handful of the labs in the world are currently using SCNT techniques in human stem cell research. (wikipedia.org)
  • Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
  • For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
  • The first cloned monkeys made with somatic cell nuclear transfer (SCNT) were born recently, according to Chinese scientists. (bioedge.org)
  • Although Zhong Zhong and Hua Hua, two genetically identical long-tailed macaques, are not the world's first cloned monkeys, they are the first to be born using SCNT. (bioedge.org)
  • The first successful SCNT monkey clones immediately sparked interest in in the dream of human cloning. (bioedge.org)
  • The primary cloning technique is called "somatic cell nuclear transfer" (SCNT). (cbc-network.org)
  • This is junk biology since implanting isn't the act of asexual reproduction: SCNT cloning is. (cbc-network.org)
  • Dolly, named after country singer Dolly Parton, was the first mammal to be cloned from an adult cell, using a process called somatic cell nuclear transfer (SCNT). (cyprus-mail.com)
  • Somatic Cell Nuclear Transfer (SCNT-Cloning) is a promising technique in many areas and is based on genetically identical individuals. (pvb.com.br)
  • One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
  • SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
  • This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
  • But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
  • This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
  • Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
  • The American Medical Association (AMA) defines human cloning as genetically identical organism's production through a process of somatic cell's nuclear transfer (SCNT). (premiumessays.net)
  • Researchers from the Chinese Academy of Sciences Institute of Neuroscience announced in a Jan. 24 article for the journal Cell that they produced two genetically-identical long-tailed macaque monkeys using a scientific technique known as somatic cell nuclear transfer (SCNT). (christian-heritage-news.com)
  • However, ethical problems were foreseen with the production by cloning of fully formed and functioning organs, as participants could not envisage how such organs could be made without first producing a cloned embryo and allowing it to grow, at least partially, through the fetal stage of development. (who.int)
  • Research advocates attack President Bush for "banning stem cell research," while pro-life advocates lament a Republican administration and Congress that have banned nothing-not embryo destruction, not human cloning, not fetal farming, not genetic engineering. (eppc.org)
  • Bovine fetal mesenchymal stem cells exert antiproliferative efect against mastitis causing pathogen Staphylococcus aureus. (sciendo.com)
  • Totipotent cells have the capacity to differentiate to all cell types, including somatic cells, germ cells, and certain cells that exist outside the embryo and are important to fetal development that are termed extraembryonic cells. (citizendium.org)
  • Dolly was the culmination of hundreds of cloning experiments that, for example, showed diploid embryonic and fetal cells could be parents of offspring. (wptv.com)
  • Production of transgenic cloned piglets from genetically transformed fetal fibroblasts selected by green fluorescent protein. (chinagene.cn)
  • Wilmut, along with Keith Campbell from the animal sciences research institute in Scotland, generated news headlines and heated ethical debates in 1996 when they created Dolly, the first mammal to be cloned from an adult cell. (cyprus-mail.com)
  • The birth and adult development of 'Dolly' the sheep, the first mammal produced by the transfer of a terminally differentiated cell nucleus into an egg, provided unequivocal evidence of nuclear equivalence among somatic cells. (bioscientifica.com)
  • It's been 20 years since scientists in Scotland told the world about Dolly the sheep , the first mammal successfully cloned from an adult body cell. (wptv.com)
  • Back in 1996, when the sheep Dolly was the first mammal cloned into existence, she was not cloned from the cells of a live animal. (khanneasuntzu.com)
  • The second way to reproduce is a strictly human invention - known as "asexual" reproduction - or more commonly, cloning. (cbc-network.org)
  • Cloning of a human being" means asexual reproduction by implanting or attempting to implant the product of nuclear transplantation [e.g., an embryo] into a uterus or substitute for a uterus with the purpose of producing a human being. (cbc-network.org)
  • So here we summarize references that address this matter for both sexual (fertilization) and asexual (twinning, cloning, etc.) human reproduction. (americanrtl.org)
  • The blastocyst stage is developed by the egg to help create embryonic stem cells from the inner cell mass of the blastocyst. (wikipedia.org)
  • After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
  • To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
  • Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
  • Most researchers obtain embryonic stem cells from the inner mass of a blastocyst, an embryonic stage when a fertilized egg has divided into 128 cells. (jcpa.org)
  • The stem cells derived from the inner mass of a blastocyst lack the ability to form a fetus when implanted into a woman, but are self-renewing and can be maintained for long periods of time in the laboratory as undifferentiated stem cells. (jcpa.org)
  • Such tissue renewal may be accomplished via the use of adult stem cells, or embryonic stem cells, which may be derived from a human embryo in the blastocyst stage. (citizendium.org)
  • However, supporters of embryonic stem cell research frequently contend that even the comparison to abortion is inappropriate, since while a several month old fetus might have sufficient neurological development to be conscious in some meaningful sense, a human embryo in the blastocyst stage has so little development that one can safely conclude that it cannot exist as a conscious being. (citizendium.org)
  • The blastocyst can then be transferred to a recipient (h) and cloned animals are born after completion of gestation (i). (biomedcentral.com)
  • In the first 4 - 5 days after fertilization, the early-stage embryo (or blastocyst) is comprised of about 150 cells, within which there is a region called the Inner Cell Mass containing the stem cells. (jewishvaluesonline.org)
  • No ethical problems were envisaged with the use of somatic cell nuclear transfer techniques which would lead directly to cloned differentiated cells or tissues such as skin, for future use by the nuclear donor. (who.int)
  • Today, we can derive stem cells from a range of adult and newborn tissues: liver cells, kidney cells, brain cells, fat cells, and umbilical cord blood. (eppc.org)
  • Comparison of human mesenchymal stromal cells from four neonatal tissues: Amniotic membrane, chorionic membrane, placental decidua and umbilical cord. (sciendo.com)
  • Transplantation of cells, tissues, or organs from another member of the same species. (nationalacademies.org)
  • Combined with the incorporation of new tools for genetic modification, these novel techniques promise to (i) transform and accelerate our understanding of genetic diseases and the development of targeted therapies through creation of tailored animal models, (ii) provide safe animal cells, tissues and organs for xenotransplantation, (iii) contribute to the preservation of endangered species, and (iv) improve global food security whilst reducing the environmental impact of animal production. (bioscientifica.com)
  • Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
  • Cloning also entails organs and tissues production through cell implantation in cultures with the real embryo that will be born. (premiumessays.net)
  • Some cells differentiate to become stem cells which produce tissues and tissues develop to become organs (National Human Genome Research Institute Para 2). (premiumessays.net)
  • In the normal course of gestation, these cells will divide and split off from one another to become every cell in the human body, forming the various organs and tissues. (jewishvaluesonline.org)
  • B cells One of the body's lines of defense ( immune system) involves white blood cells (leukocytes) that travel through the bloodstream and into tissues, searching for and attacking microorganisms and. (msdmanuals.com)
  • genic models are inadequate for number of activated CD8-positive T LMP1 was strongly expressed in the understanding the cancer etiology in cells increased considerably in the lymphoma tissues but was hardly the context of natural viral infection. (who.int)
  • In January 2018, a team of scientists in Shanghai announced the successful cloning of two female crab-eating macaques (named Zhong Zhong and Hua Hua) from foetal nuclei. (wikipedia.org)
  • Somatic cell nuclear transplantation has become a focus of study in stem cell research. (wikipedia.org)
  • The disease specific stem cell lines could then be studied in order to better understand the condition. (wikipedia.org)
  • In the United States, scientists at the Harvard Stem Cell Institute, the University of California San Francisco, the Oregon Health & Science University, Stemagen (La Jolla, CA) and possibly Advanced Cell Technology are currently researching a technique to use somatic cell nuclear transfer to produce embryonic stem cells. (wikipedia.org)
  • What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
  • This form of cloning is unrelated to stem cell research. (eurostemcell.org)
  • So when I was recently contacted by an earnest and amiable member of a local school board who was concerned about the questionable manner in which the issue of "stem cell" research - both human embryonic and adult - was presented to the high school students in his district in a currently-used science textbook, I agreed to evaluate that section in the text for him. (lifeissues.net)
  • My edited analysis of the section on "stem cell research" in this science textbook is copied below. (lifeissues.net)
  • In my opinion there is no question but that the scientific information on stem cell research included in this science text book being used in Illinois schools incorporates some inaccurate scientific facts, and seems to be very partial to the use of human embryonic "stem cell" research. (lifeissues.net)
  • Cellular differentiation begins with the fertilized egg which serves as the identifying characteristic of an embryonic stem cell. (jcpa.org)
  • In addition, specific proteins or biological substances can be added to these stem cell cultures to transform them in the laboratory into a large variety of specialized cell types, such as nerve, liver, muscle, bone, and blood cells. (jcpa.org)
  • In 2009, in a major reversal of U.S. policy, President Obama signed an executive order pledging to "vigorously support" embryonic stem cell research. (jcpa.org)
  • That's why Father Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia, said that the efforts to help people understand the immorality of embryo reserch, including human cloning, must focus on humanizing the issue and appreciating our own embryonic origins, not just on the desired results of embryonic or other types of stem-cell research. (archstl.org)
  • A decade later, cloning came to the forefront in Missouri with the narrow passage of Amendment 2, a ballot initiative in 2006 that constitutionally protects embryonic stem-cell research and human cloning. (archstl.org)
  • This is our sad state of stem cell affairs. (eppc.org)
  • But if we are to make wise policy the stem cell/cloning arena, we need to step back, sort out the various scientific alternatives and moral issues, and search for a way forward that all citizens can embrace. (eppc.org)
  • To this end, we offer a detailed analysis of the stem cell/cloning question-where is the science, what are the political alternatives, and what moral obligations should guide us? (eppc.org)
  • Last May, the House of Representatives passed a bill to create a cord blood stem cell bank, legislation that is likely to become law with virtually unanimous support. (eppc.org)
  • These moral perils are surely not a reason to oppose adult stem cell research, which deserves vigorous and expanded public support. (eppc.org)
  • The bill purports to promote stem-cell research, while outlawing the cloning of a human being. (cbc-network.org)
  • While stem-cell research holds enormous potential for treating or even curing some diseases, the cloning of a human being is morally and ethically unacceptable…Any attempt to clone a human being is in direct conflict with the public policies of this state. (cbc-network.org)
  • Stem Cell Res. (sciendo.com)
  • The term stem cell is generally used to describe cells that are totipotent , pluripotent , or multipotent . (citizendium.org)
  • The term stem cell is also used in reference to any adult cells that are capable of assisting in the restoration of adult tissue via self-renewal. (citizendium.org)
  • After sixteen weeks, the injured mice who received human stem cell injections experienced a significant improvement in the motor functions that had been impaired by their injuries. (citizendium.org)
  • Adult stem cells hold great promise in mitigating much of the ethical debate over embryonic stem cell use. (citizendium.org)
  • Dolly was an important milestone, inspiring scientists to continue improving cloning technology as well as to pursue new concepts in stem cell research. (wptv.com)
  • By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
  • The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
  • However, it should be noted that these morality principles cannot be valued instantaneously in the stem cell study (ESC 1). (premiumessays.net)
  • I. Introduction The progress of stem cell research was a significant turning point in history and certainly caught the attention of scientific medicine. (proficientwriters.net)
  • Stem cell research is being followed to achieve medical developments and breakthroughs in science. (proficientwriters.net)
  • Once scientists and researchers realized stem cell potential, they aimed to create therapies and treatments to replace and rebuild. (proficientwriters.net)
  • Stem cell technology is the latest development in this controversial branch of science. (edu.au)
  • Embryonic stem cell technology is still at a preliminary research stage and announcements about its potential may be premature. (edu.au)
  • The ethical and legal controversies that were aroused in the ART debates during the 1980s have been re-ignited with the development of stem cell technology. (edu.au)
  • Experts from around the world are assessing the difficult issue of the extent to which embryonic stem cell research should be allowed to proceed, and to date there is little international consensus on this matter. (edu.au)
  • How, then, should embryonic stem cell research be regulated in Australia? (edu.au)
  • This issue was considered by the House of Representatives Standing Committee on Legal and Constitutional Affairs in its report entitled Human Cloning: Scientific, Ethical and Regulatory Aspects of Human Cloning and Stem Cell Research (hereafter the Andrews Report , after the Chair of the Committee, Mr Kevin Andrews, MP) released in September 2001. (edu.au)
  • In this article we examine embryonic stem cell research and explore the current regulatory framework associated with this research in Australia, with particular reference to the Andrews Report . (edu.au)
  • Stem cell technology in humans derives from earlier and complementary work in animal studies. (edu.au)
  • What is the Jewish perspective on stem cell research? (jewishvaluesonline.org)
  • A few years ago, in an article in the The Times of London newspaper, the author, Michael Gove, made the following statement: "Embryonic stem-cell experimentation involves not just the destruction of human life but the creation of life with the specific intent to destroy it. (jewishvaluesonline.org)
  • If embryonic stem-cell research offers real possibilities for future cures then, from a Jewish point of view, it may be pursued with caution, humility, and strict supervision. (jewishvaluesonline.org)
  • Inherited bone marrow failure syndromes (IBMFS) are usually the result of intrinsic stem cell/progenitor defects. (medscape.com)
  • Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)
  • Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
  • We discuss these properties with examples both from the hematopoietic and embryonic stem cell (ESC) systems. (lu.se)
  • The nature of the stem cell substates and their relationship to commitment to differ- entiate and lineage selection can be elucidated in terms of a landscape picture in which stable states can be defined mathematically as attractors. (lu.se)
  • Donor fibroblasts were obtained from an ear-skin biopsy of a male Afghan hound and cultured for two to five passages (in which fully grown cells are transferred to a new culture dish). (nature.com)
  • Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
  • The microenvironment, consisting of lymphocytes, macrophages, fibroblasts, endothelial elements, and stroma in which hematopoietic cells reside, creates a regulatory niche that determines the local area network. (medscape.com)
  • 2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)
  • that is histopathological y very simi- T cel s, B cel s, natural kil er cel s, LMP1 of EBV can transform ro- lar to that caused by hepatitis B vi- macrophages, and dendritic cells, dent fibroblasts and is expressed rus (HBV) in humans, but it does so and this humanized mouse model in most of the human cancers as- through a different mechanism. (who.int)
  • The technique consists of taking an denucleated oocyte (egg cell) and implanting a donor nucleus from a somatic (body) cell. (wikipedia.org)
  • Pregnancy was established only after embryo transfer of very-early-stage nuclear-transfer constructs (that is, less than 4 hours after oocyte activation). (nature.com)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • Somatic cell cloning (cloning or nuclear transfer) is a technique in which the nucleus (DNA) of a somatic cell is transferred into an enucleated metaphase-II oocyte for the generation of a new individual, genetically identical to the somatic cell donor (Figure 1 ). (biomedcentral.com)
  • A matured oocyte (c) is then enucleated (d) and a donor cell is transferred into the enucleated oocyte (e). (biomedcentral.com)
  • Similarly, there was interest in using the procedure to produce cloned tissue and organs for possible future transplantation in the nuclear donor and perhaps other tissue- compatible recipients. (who.int)
  • It is the policy of Washington state that research involving the derivation and use of human embryonic stem cells, human embryonic germ cells, and human adult stem cells from any source, including somatic cell nuclear transplantation , is permitted upon full consideration of the ethical and medical implications of this research. (cbc-network.org)
  • Cross-species transplantation was possible without the rejection of the human embryonic stem cells by the mice's immune systems because the mice were genetically modified to suppress certain immune responses that would have interfered with transplantation. (citizendium.org)
  • Cloning by nuclear transfer using mammalian somatic cells has enormous potential application. (biomedcentral.com)
  • The formation of one or more genetically identical organisms derived by vegetative reproduction from a single cell. (childrensmercy.org)
  • 3.5.U5 Clones are groups of genetically identical organisms, derived from a single original parent cell. (biologyforlife.com)
  • In 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become pluripotent stem cells, which have the capacity to produce many different types of cells. (asu.edu)
  • They called the pluripotent stem cells that they produced induced pluripotent stem cells (iPSCs) because they had induced the adult cells, called differentiated cells, to become pluripotent stem cells through genetic manipulation. (asu.edu)
  • The proliferation and differentiation of pluripotent stem cells give rise to progeny that can populate the entire immunologic and hematopoietic systems through committed progenitors of both the lymphoid and myeloid lineages. (medscape.com)
  • But there was no way to easily know all the characteristics of the animal that would result from a cloned embryo or fetus. (wptv.com)
  • There is now no barrier for cloning primate species, thus cloning humans is closer to reality. (bioedge.org)
  • Properly controlled, adequately sized studies have yet to demonstrate that human embryonic stem cells have medical value in humans. (citizendium.org)
  • But they warned that two monkeys engineered by Chinese researchers must not become a step toward cloning humans. (christian-heritage-news.com)
  • One exception is hu- humanized SCID mice, the use of al oncogenic viruses that are strictly man T-cell lymphotropic virus type 1 surrogate hosts has not proven very species-specific, causing cancer in (HTLV-1): in addition to its ability to useful for defining tumour site con- humans only. (who.int)
  • These data document for the first time that a substantial proportion of wild monkeys in Cameroon are SIV infected and that humans who hunt and handle bushmeat are exposed to a plethora of genetically highly divergent viruses. (cdc.gov)
  • This review discusses recent advances that build on the conceptual legacy of nuclear transfer and - when combined with gene editing - will have transformative potential for medicine, biodiversity and sustainable agriculture. (bioscientifica.com)
  • This study aimed to characterize the methylation pattern of the exon 10 regions of the IGF2 gene and the Imprinting Control Region (ICR) of the H19 gene in the placenta of cloned calves. (pvb.com.br)
  • 3] Watanabe S, Iwamoto M, Suzuki SI, Fuchimoto D, Honma D, Nagai T, Hashimoto M, Yazaki S, Sato M, Onishi A. A novel method for the production of transgenic cloned pigs: electroporation-mediated gene transfer to non-cultured cells and subsequent selection with puromycin. (chinagene.cn)
  • Methods for gene identification and analysis of gene structure: cloning, PCR, restriction mapping, in situ hybridisation, DNA sequencing. (lu.se)
  • Molecular mechanisms for regulation of gene expression at different levels: remodeling of chromatin, initiation of transcription, nuclear transport and signalling, and RNA interference. (lu.se)
  • Gene regulation in developmental biology and the cell cycle. (lu.se)
  • Strategies for gene therapy and production of medicines via genetically-modified organisms (expression vectors and viral vectors). (lu.se)
  • Similarly, GATA-1 has been shown to induce lineage switching expression values even if, for simplicity, we assume only ``on'' of committed cells in hematopoiesis, first in cell lines (Kulessa and ``off'' states for each gene. (lu.se)
  • In reality, gene somatic cells to a pluripotent cell state by a handful of transcrip- expression is graded, making the potential gene expression tion factors (Takahashi and Yamanaka, 2006). (lu.se)
  • These developmental defects have been attributed to incomplete reprogramming of the somatic nuclei by the cloning process. (biomedcentral.com)
  • These observations suggest that further studies on nuclear reprogramming are needed in order to understand the underlying mechanisms of reprogramming and significantly improve the ability of the differentiated somatic nuclei to be reprogrammed. (biomedcentral.com)
  • Biologists have developed techniques for artificial manipulation of DNA, cells and organisms. (biologyforlife.com)
  • Mechanisms that regulate development from single cell to multicellular organisms. (lu.se)
  • This policy is similar to that of other countries, including Israel, where scientists are funded by Government to study embryonic stem cells despite the aforementioned bioethical issue. (jcpa.org)
  • Long before the controversy emerged over human embryonic stem cells, scientists and doctors began using first-generation stem cells from adult bone marrow. (eppc.org)
  • But they are also less equipped to produce every cell type of the body and less able to reproduce themselves indefinitely, which makes them less appealing to scientists interested in basic research. (eppc.org)
  • In July 2005, for example, scientists announced that they had engineered adult mouse stem cells into usable mouse eggs, a technique that might one day allow for the creation of human eggs from ordinary human cells. (eppc.org)
  • Scientists plan to use somatic cell nuclear transfer for the first human clone, which is the same technique that was used to create Dolly the sheep. (humansfuture.org)
  • 3.5.NOS Assessing risks associated with scientific research- scientists attempt to assess the risks associated with genetically modified crops or livestock. (biologyforlife.com)
  • Because the early stem cells have the ability to become any one of the hundreds of different kinds of human cells, scientists are working on research using these cells with the aim of creating therapies to treat a variety of diseases. (jewishvaluesonline.org)
  • The cloning method used by the Chinese scientists "should not become a test case for the perfection of human cloning techniques," said Raymond Johnson, a Pennsylvania pastor who received a financial award from Trinity International University last year to help him study the relationship between Christianity and science. (christian-heritage-news.com)
  • The aim of carrying out this procedure is to obtain pluripotent cells from a cloned embryo. (wikipedia.org)
  • In this procedure, the nucleus of an egg cell is removed and replaced by the nucleus of a cell from another adult. (eurostemcell.org)
  • As such, cloning refers to a procedure via which the production of a baby with a genetic factor that is identical to that of the parents occurs. (premiumessays.net)
  • Various strategies have been employed to modify donor cells and the nuclear transfer procedure in attempts to improve the efficiency of nuclear transfer. (biomedcentral.com)
  • Even while clones are genetically identical, their phenotypes - the characteristics they express - will be different. (wptv.com)
  • For this study, female and male cloned calves presenting different phenotypes were used. (pvb.com.br)
  • A significant difference was found between controls and clones with healthy phenotypes for the ICR/H19 region. (pvb.com.br)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • However, changing the genetic code of the host cell, as well as that of the cellular machinery that reads and expresses the viral genome, could thwart the virus's ability to infect cells. (khanneasuntzu.com)
  • In this study, we employed a genome-wide CRISPR-Cas9 loss-of-function screen based on cell survival in order to identify genes implicated in the host response to dsRNA. (cnrs.fr)
  • Using a genome-wide screening approach, we set to identify genes involved in dsRNA entry, sensing, and apoptosis induction in human cells. (cnrs.fr)
  • [ 7 , 8 ] Sister chromatid exchanges are considered a sensitive indicator for cell genome instability, as they are thought to be the outcome of DNA double-strand breaks resulting from homologous recombination repair. (medscape.com)
  • explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)
  • If Naegleria core genome was enriched in conserved genes essential for metabolic, regulatory and survival processes, the accessory genome revealed the presence of genes involved in stress response, macromolecule modifications, cell signaling and immune response. (cdc.gov)
  • your supposed cloning ban actually authorizes human cloning, implantation, and gestation through the ninth month. (cbc-network.org)
  • That is what New Jersey legislators did when they passed and then Governor James McGreevey signed S-1909 last year, a law that was sold to the public as outlawing human cloning but which actually permits the creation of cloned human life, and its implantation and gestation up to and including the very moment prior to the emergence of the cloned baby from the birth canal. (cbc-network.org)
  • These germ cells are the only ones in the body that have their genetic material all jumbled up and in half the quantity of every other kind of cell. (wptv.com)
  • Since germ therapy is too late for everyone alive, we have to correct the genotype of a significant number of our somatic cells or replace them by new ones. (senescence.info)
  • Quantitative RT-PCR and in situ hybridization detected the expression of PRL not only in Leydig cells but also in germ cells, in particular in spermatogonia. (go.jp)
  • The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
  • The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)
  • Father Tad Pacholczyk is convinced that embryonic stem cells will someday cure diseases. (archstl.org)
  • Already, non-embryonic stem cells are being used to treat a variety of diseases-most notably certain cancers of the blood. (eppc.org)
  • These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
  • Both diseases show phenotypical similarity and both demonstrate bone marrow failure, skeletal growth deficiency, short stature, and predisposition to hematological malignancies, although they are genetically unrelated. (medscape.com)
  • Developmental defects, including abnormalities in cloned fetuses and placentas, in addition to high rates of pregnancy loss and neonatal death have been encountered by every research team studying somatic cloning. (biomedcentral.com)
  • It became a hot topic in 1996 when Dolly the sheep was cloned via a process called somatic cell nuclear transfer. (archstl.org)
  • British scientist Ian Wilmut, whose research was central to the creation of the cloned animal, Dolly the Sheep, has died at the age of 79, the University of Edinburgh said on Monday. (cyprus-mail.com)
  • Outline the production of Dolly the sheep using somatic cell nuclear transfer. (biologyforlife.com)
  • SHANGHAI (BP) -- The first-ever primates cloned through a technique that produced Dolly the sheep have been cited by Christian bioethicists as a potentially valuable development in animal research. (christian-heritage-news.com)
  • The Church also supports research and therapies using adult stem cells, which are cells that come from any person who has been born - including umbilical cord blood, bone marrow, skin and other organs. (archstl.org)
  • And recent experimental trials, while still very preliminary, suggest that adult stem cells may one day help us treat a host of terrible pathologies. (eppc.org)
  • Yet for now, the utility of adult stem cells also remains limited. (eppc.org)
  • Adult stem cells are easier to control than embryonic stem cells and thus less likely to form tumors. (eppc.org)
  • In addition, the possibility of reprogramming adult stem cells back to a "pluripotent" (or embryonic-like) state raises the biological prospect of going back too far. (eppc.org)
  • Cells are collected from donor (a) and cultured in vitro (b). (biomedcentral.com)
  • Cloned transgenic swine via in vitro production and cryopreservation. (chinagene.cn)
  • Furthermore, the use of diphtheria toxin -- which is far more toxic to human cells than mouse cells -- to destroy the human neurons in the mice reversed the observed improvements in motor function. (citizendium.org)
  • Normally 46 chromosomes, including two sex chromosomes are found in the nucleus of human cells. (edu.au)
  • Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)
  • By challenging HCT116 human cells with either synthetic dsRNA or Sindbis virus (SINV), we identified the heparan sulfate (HS) pathway as a crucial factor for dsRNA entry, and we validated SINV dependency on HS. (cnrs.fr)
  • Interestingly, we uncovered a novel role for COG4, a component of the conserved oligomeric Golgi (COG) complex, as a factor involved in cell survival to both dsRNA and SINV in human cells. (cnrs.fr)
  • Similarly, when the fertilized egg divides from two cells into four cells, each of these four cells has the potential to individually form a human fetus. (jcpa.org)
  • However, by the time the fertilized egg divides into 8 or 16 cells something changes and each respective cell, if separated, no longer has the potential to create a fetus. (jcpa.org)
  • The source nuclear material can be embryo-derived, fetus-derived, or taken from an adult somatic cell. (childrensmercy.org)
  • The endgame was never meant to be armies of genetically identical livestock: Rather, researchers continue to refine the techniques and combine them with other methods to turbocharge traditional animal breeding methods as well as gain insights into aging and disease. (wptv.com)
  • It demonstrated that genes inactivated during tissue differentiation can be completely re-activated by a process called nuclear reprogramming: the reversion of a differentiated nucleus back to a totipotent status. (biomedcentral.com)
  • As the fertilized egg divides from one cell into two, physicians can separate these two cells and implant each one of them into a woman's uterus to generate two genetically identical children. (jcpa.org)
  • Viruses whose particles (virions) are surrounded by a lipid bilayer derived by budding from the cell membrane. (nationalacademies.org)
  • This leads to the release of new viruses that proceed to infect other cells, which in turn produce yet more virus particles, and so on. (khanneasuntzu.com)
  • Viruses can take control of a cell's genetic machinery because both the virus and the cell share the same genetic code. (khanneasuntzu.com)
  • 1940s and consisted of partially purified preparations of procedures based on limiting dilutions or cloning with influenza viruses grown in embryonated eggs. (cdc.gov)
  • Animal models for human tumour mental animals is not easy to answer does induce adult T-cell leukaemia/ viruses that make use of animal virus- for these agents, because cancer bi- lymphoma (ATLL), albeit in monkeys es are scarce. (who.int)
  • These results show that LMP1 , mour viruses classified by IARC in EBV-specific T-cell response. (who.int)
  • Analysis of eight canine-specific microsatellite loci confirmed that the cloned dogs were genetically identical to their donor dog. (nature.com)
  • Uncompleted epigenetic reprogramming is attributed to the low efficiency of producing transgenic cloned animals. (chinagene.cn)
  • TSA improve transgenic porcine cloned embryo development and transgene expression[J]. HEREDITAS, 2011, 33(7): 749-756. (chinagene.cn)
  • Inoculation with a high dose strains of LMP1 transgenic mice vide a powerful tool in mechanistic of EBV caused a B-cell lymphopro- were established that express LMP1 studies on the role of individual viral liferative disorder in these mice, under the control of the immunoglob- genes in cancer. (who.int)
  • The potential of intra-articular injection of chondrogenic-induced bone marrow stem cells to retard the progression of osteoarthritis in a sheep model. (sciendo.com)
  • Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stem Cells from Sheep: Culture Characteristics. (sciendo.com)
  • He led efforts to develop cloning, or nuclear transfer, techniques that could be used to make genetically modified sheep. (cyprus-mail.com)
  • This involved taking a sheep egg, removing its DNA and replacing it with DNA from a frozen udder cell of a sheep that died years before. (cyprus-mail.com)
  • Dolly was an exact genetic copy of that sheep - a clone. (wptv.com)
  • She lived to six and a half years, when she was eventually put down after a contagious disease spread through her flock, infecting cloned and normally reproduced sheep alike. (wptv.com)
  • Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
  • 1. Cloning is an umbrella term traditionally used to describe different processes for duplicating biological material. (who.int)
  • Describe different ways in which natural clones can arise. (biologyforlife.com)
  • In Dolly's case, the cell came from the mammary gland of an adult ewe. (eurostemcell.org)
  • Adipose stem cells in reparative goat mastitis mammary gland. (sciendo.com)
  • What was special about Dolly is that her "parents" were actually a single cell originating from mammary tissue of an adult ewe. (wptv.com)
  • When the one-cell embryo duplicates its genetic material, both cells of the now two-cell embryo are genetically identical. (wptv.com)
  • We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
  • BML mutations thus result in defects in DNA repair and genomic instability in the somatic cells, predisposing the patients to cancer development. (medscape.com)
  • The overall result of the genomic instability in the proliferating cells is a high risk of malignancy, reduced fertility or infertility, B- and T-cell immunodeficiencies, and cutaneous manifestations, including photosensitivity, poikiloderma, and telangiectatic erythema. (medscape.com)
  • The nucleus of a body cell from the DNA donor is removed, and put into the place formerly occupied by the egg's nucleus. (cbc-network.org)
  • The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
  • For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
  • The predominant bioethical concern arising from this technology is that the blastocyt-stage embryo must be destroyed in the process of isolating and separating the embryonic stem cells from the inner mass region of the pre-embryo. (jcpa.org)
  • In this process, researchers remove the genetic material from an egg and replace it with the nucleus of some other body cell. (wptv.com)
  • Schematic diagram of the somatic cloning process. (biomedcentral.com)
  • Dolly was a product of nuclear transfer cloning, a process in which a cell nucleus of the animal to be cloned is physically transferred into an egg cell whose nucleus had previously been removed. (khanneasuntzu.com)
  • In his experiments, Bridges studied Drosophila, the common fruit fly, and by doing so showed that a process called nondisjunction caused chromosomes, under some circumstances, to fail to separate when forming sperm and egg cells. (asu.edu)