Cells from dogs. Medical search. Frequent questions

Mast cells in dogs are particularly likely to develop the mutations necessary to start growing uncontrollably, and it is not uncommon for dogs to have small mast cell tumors. (vetinfo.com)
If a mast cell tumor becomes malignant, the dog is diagnosed with cancer, and has a significantly reduced chance of survival, so mast cell tumors are often removed using surgery before they get a chance to become malignant. (vetinfo.com)
What Dogs Are Prone to Mast Cell Tumors? (vetinfo.com)
While it is uncommon for humans or cats to develop mast cell tumors, all ages and breeds of dogs are at risk. (vetinfo.com)
There are some canines that are more likely to develop mast cell tumors than others, including Golden Retrievers and the brachiocephalic breeds (dogs with a short, flattened snout and a wide head, such as Boxers, Pugs, and Bulldogs). (vetinfo.com)
Risk of mast cell tumor development is hereditary, so dogs are more likely to have mast cell tumors if their parents had them. (vetinfo.com)
Mast cell tumors do not usually form on young canines, but are much more likely to develop on dogs that are between eight and nine years of age. (vetinfo.com)
Grade two mast cell tumors extend below the skin, and show some signs of malignancy. (vetinfo.com)
Grade three mast cell tumors are the most dangerous. (vetinfo.com)
Since grade one and grade two mast cell tumors are close to the surface of the skin, cutting them off of the dog's body is an easy cure. (vetinfo.com)
Grade three mast cell tumors extend too far inside the body to be removed with surgery, and are usually treated with radiation therapy or chemotherapy. (vetinfo.com)
All mammals have mast cells, but canine mast cells are the most likely out of all mammals to become cancerous tumors. (vetinfo.com)
Surgical treatment is designed to eliminate small tumors such as grade one and two mast cell tumors, and, as long as the tumor has not yet reached malignancy, it is the most effective treatment. (vetinfo.com)
Unfortunately, the squished-nosed dogs of the world are not the only ones who get mast cell tumors. (dogsnaturallymagazine.com)
What Are Mast Cell Tumors? (dogsnaturallymagazine.com)
Mast cell tumors (MCTs) happen mostly on the skin but sometimes in the internal organs . (dogsnaturallymagazine.com)
On Monday, the US Food and Drug Administration (FDA) approved Stelfonta (tigilanol tiglate injection) to treat nonmetastatic, skin-based mast cell tumors (MCTs) in dogs. (aaha.org)
Another common and potentially deadly type of cancer are Mast Cell Tumors. (thehonestkitchen.com)
Mast cell tumors (MCT, or mastocytoma) are collections of cancerous mast cells that form a mass-like lesion. (thehonestkitchen.com)
Cancer occurs when cells that have lost their ability to stop dividing, grow in an out-of-control manner and form tumors. (thehonestkitchen.com)
Background Tumor infiltrating NK (TINK) cells are present and linked to prognosis in many solid tumors. (bmj.com)
Knowing how to recognize common signs of mast cell tumors in dogs can help you catch them early. (embarkvet.com)
Here, we'll explain what mast cell tumors are, how genetics and breed ancestry affect our risk model, and the steps you can take if you know your dog's risk. (embarkvet.com)
Mast cell tumors (MCT) are the most common type of malignant skin tumor found in dogs. (embarkvet.com)
If caught early, mast cell tumors are treatable. (embarkvet.com)
More than 80% of mast cell tumors are curable by surgery alone. (embarkvet.com)
What are the signs and symptoms of mast cell tumors in dogs? (embarkvet.com)
In addition to knowing the signs to look out for, knowing your dog's risk for developing mast cell tumors is a key part of management. (embarkvet.com)
How does Embark determine genetic risk for mast cell tumors in dogs? (embarkvet.com)
Powered by Embark Research and our customers, this novel method uses several genetic factors to calculate an estimated risk of mast cell tumors for both single-breed and mixed-breed dogs of specific origin. (embarkvet.com)
To investigate the chromosomal fragility, we researched by cytogenetic technique in the peripheral blood lymphocytes cultures and in the tumors cells cultures from canines presenting oral and cutaneous warts lesions. (fiocruz.br)
Although squamous cell carcinoma is the most common primary malignant tumor of the oral cavity, the most common tumors of the hard palate are of minor salivary gland origin. (medscape.com)

Dr. Dressler and Dr. Ettinger discuss the detection, diagnosis, and Full Spectrum Care Approach to treatment of transitional cell carcinoma in dogs. (dogcancerblog.com)
The symptoms of transitional cell carcinoma in dogs are typical of other more common conditions like a urinary bladder infection and bladder stone. (petinsurancequotes.com)

Polarized endocytosis by Madin-Darby canine kidney cells transfected with functional chicken liver glycoprotein receptor. (rupress.org)
We have studied the expression of the chicken hepatic glycoprotein receptor (chicken hepatic lectin [CHL]) in Madin-Darby canine kidney (MDCK) cells, by transfection of its cDNA under the control of a retroviral promotor. (rupress.org)
Structure and assembly of desmosome junctions: biosynthesis and turnover of the major desmosome components of Madin-Darby canine kidney cells in low calcium medium. (rupress.org)

Suitable for small and medium size dog breeds. (chewy.com)
Well, this tumor is most common cancer of the urinary tract that you see more in dogs or in certain breeds like Scottish and also dogs that are more overweight or obese. (dogcancerblog.com)
Although this is very helpful in the early detection of TCC particularly in predisposed breeds, it is important to note that 15% of dogs with TCC will test negative for BRAF mutation. (petinsurancequotes.com)
Twenty-four dogs of different breeds between 1 and 10 years of age with acute and chronic wounds were studied. (biomedcentral.com)
In fact, adipose mesenchymal stem cells (ASCs) are being used, especially in small breeds where the amount of bone marrow that can be harvested is limited and the collection is more laborious and painful. (biomedcentral.com)
They are usually seen in small breeds and older dogs' (of more than10 years). (petmoo.com)
Which dog breeds are included in the mast cell tumor risk model? (embarkvet.com)
Any dog can develop a mast cell tumor, but some breeds are more susceptible than others. (embarkvet.com)
Dogs with ancestry in other breeds can also develop MCT. (embarkvet.com)
While lymphoma can affect any type of dog, large breeds such as Boxers, Retrievers, and Shepherds are most commonly affected. (naturalpet.health)
Since the life spans of other breeds vary, further studies are needed to find out the real age of every very good dog, the scientists say. (sciencenews.org)

Cutaneous round cell tumours (CRCTs) (including mast cell tumours, histiocytic neoplasms, plasmacytomas, lymphomas and melanomas) comprise a significant proportion of these masses. (thewebinarvet.com)
In dogs, almost 5-10 % of cutaneous neoplasms are SCC. (petmoo.com)
The findings documented as mucosal and cutaneous tropism, which the PV viral infection not confined only epithelial sites, but also involved intracellular genome of host cell. (fiocruz.br)

The aim of the present study was to evaluate the clinical relevance of determining AMH concentration in peripheral blood in the diagnostic workup of dogs with suspected testicular tumours. (vin.com)
This supports the use of canine MSC transplants or their secreted products in the clinical treatment of dogs with neurological disorders and provides some insight into possible mechanisms of action. (aston.ac.uk)
CBD is effective at hindering cell proliferation and induction of autophagy and apoptosis rapidly across neoplastic cell lines and further clinical trials are needed to understand its efficacy and interactions with traditional chemotherapy. (wildliferx.com)
In this paper, we evaluated the clinical value and safety of the application of cultured allogenic MSCs from AT for acute and chronic skin wound healing in a canine model. (biomedcentral.com)
The development of an allogenic ASC therapy to improve wound healing in a canine model could have a clinical impact in human treatment. (biomedcentral.com)
Adult mesenchymal stem cells (MSCs) have been widely used in regenerative medicine in both in vitro and in vivo preclinical research and clinical trials. (biomedcentral.com)
In the present study, we reported about papillomavirus (PV) clinical infection and viral latent investigation in canines. (fiocruz.br)
Clinical and molecular analyses for detection of DNA PV infection, as well as histopathology examination and cytogenetic evaluation were carried out in clinical lesions canines. (fiocruz.br)
[ 5 ] Their landmark paper included laboratory studies in a canine model and clinical results in 30 adult patients with a variety of gastrointestinal (GI) maladies ranging from achalasia to traumatic pancreatitis to regional enteritis. (medscape.com)

In order to properly identify a lump on your dog's skin as a mast cell tumor, you have to take the dog in to the veterinarian, where a biopsy of the tumor must be performed. (vetinfo.com)
A mast cell tumor diagnosis rates the tumor according to how dangerous it is. (vetinfo.com)
The most common treatment for a mast cell tumor is surgery. (vetinfo.com)
If the lump is detected early, the mast cell tumor will have less time to develop into a serious problem before it is surgically removed. (vetinfo.com)
If you suspect a mast cell tumor, take your dog to the vet for diagnosis so that you can decide on the best treatment option. (dogsnaturallymagazine.com)

They've become a common diagnosis and an inevitable fear for most dog owners. (dogsnaturallymagazine.com)
AMH is a promising biomarker for the diagnosis of Sertoli cell tumours in dogs. (vin.com)
Once there's a diagnosis of transitional cell carcinoma, treatment hugely depends on the stage of the disease. (petinsurancequotes.com)

At the RVC Stem Cell Centre, we prepare autologous mesenchymal stem cells in our Veterinary Medicines Directorate-licenced laboratory and under the same quality control as for horse stem cells. (rvc.ac.uk)
Mesenchymal stem cells (MSCs) are "adult" or tissue-resident stem cells. (rvc.ac.uk)
Mesenchymal stem cells (MSCs) have been used in cell replacement therapies for connective tissue damage, but also can stimulate wound healing through paracrine activity. (aston.ac.uk)

Feline panleukopenia virus (FPV) is a pathogen whose canine-adapted form (canine parvovirus (CPV)) emerged in 1978. (nih.gov)
Are you aware that there are many types of cancer your canine or feline companion can develop? (thehonestkitchen.com)

Finally, analysis of the mechanism by which multimeric alpha-lactalbumin induces apoptosis in transformed epithelial cells could lead to the design of antitumor agents. (lu.se)

Thanks to advancements in science, your vet can now test tumor cells to find out 2 important things: the "grade" and the "stage" of the tumor. (dogsnaturallymagazine.com)
1 While these cells may have potent antitumor effector function, they are thought to be dysfunctional in the tumor microenvironment (TME). (bmj.com)
Methods Canine sarcoma tumor specimens were cut into fragments and cultured individually in 24-well plates with medium supplemented with 6000 IU/ml of rhIL-2. (bmj.com)
While most TINKs and TILs were able to kill autologous tumor and resulted in increased Granzyme B expression, we surprisingly found that the number of TINKs (NKp46+) was positively corelated with tumor killing, with pure cultures of NKp46+ cells resulting in complete and efficient tumor elimination. (bmj.com)
Furthermore, the percentage of CD5+ T cells was negatively corelated with tumor killing. (bmj.com)
Compared with the less potent TIL cultures composed of mainly CD5+ T cells, NKp46+ TINKs secreted significantly higher T1 cytokines (IFN-γ, TNF-α and GM-CSF) after co-cultured with tumor. (bmj.com)
Conclusions Our results demonstrated that functional TINKs can be efficiently expanded from canine sarcoma tumor tissue with little NK cell infiltration seen by immunohistochemistry. (bmj.com)
The malignant tumor is usually found in the lower part of the urinary bladder, and could possibly affect the urethra, the duct that drains urine away from the body, as well as the prostate gland of male canines. (petinsurancequotes.com)
Approximately 30% of dogs with transitional cell carcinoma release tumor cells in the urine so the illness can sometimes be detected through urinalysis alone. (petinsurancequotes.com)
This non-invasive technique uses a urine sample from the dog to diagnose this type of tumor even in its early stages when the dog is not showing any symptoms and no tumor is detected on any imaging test. (petinsurancequotes.com)
Unlike other cancer types, surgery is often not an option with transitional cell carcinoma because it's almost impossible to completely excise the tumor. (petinsurancequotes.com)
In general, most dogs with SCC will go on to develop the metastatic disease even with complete removal of the local oral tumor. (petmoo.com)
Treatment regimen for Squamous cell carcinoma is intended for controlling the primary tumor and dealing with the concern for metastasis. (petmoo.com)

This presentation provides a brief overview of round cell tumours in dogs as well a review of several case examples. (thewebinarvet.com)

On the Honest Kitchen Blog I've covered Lymphoma, a type of white blood cell cancer see article here . (thehonestkitchen.com)
It appears to be effective in both B- and T-cell lymphoma. (naturalpet.health)
Unlike traditional chemotherapy, which targets and attacks ANY dividing cells in the body-hence the side effects of hair loss, nausea, etc- Tanovea preferentially targets and attacks only the cells causing lymphoma . (naturalpet.health)
It is effective in 60-80% of cases of lymphoma, and works best with B cell types which have not previously undergone chemotherapy. (naturalpet.health)
Lymphoma in dogs can take many different forms. (naturalpet.health)
There are two basic types of lymphoma, B cell and T cell. (naturalpet.health)
About 2/3 of lymphoma cases are of the B cell type, which carries a better prognosis than does T cell lymphoma. (naturalpet.health)
Dogs with B-cell lymphoma will generally live longer than those with T-cell lymphoma. (naturalpet.health)
Listen, there are no good studies supporting the use of integrative therapy to help dogs fight lymphoma. (naturalpet.health)
HERE ARE SEVEN NATURAL WAYS TO FIGHT LYMPHOMA IN DOGS- Each proven in multiple human Non-Hodgkins lymphoma studies, as listed on GreenMedInfo.com. (naturalpet.health)
Because of the poor long term prognosis associated with lymphoma in dogs, regardless of treatment, some pet lovers opt to keep things simple by treating their dog with prednisone alone. (naturalpet.health)
The most common recommendation for aggressive treatment of lymphoma in dogs is ROTATIONAL CHEMOTHERAPY , where a rotation of four oral or injectable drugs is used to kill any rapidly-dividing cell in the body. (naturalpet.health)
Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. (bvsalud.org)
Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs . (bvsalud.org)
We thus confirm the validity of this classification scheme across widely divergent mammalian taxa and add to the growing body of literature suggesting cellular and molecular similarities between human and canine non-Hodgkin lymphoma. (bvsalud.org)

A canine mast cell is part of a dog's immune system. (vetinfo.com)
Mast cells are part of your dog's immune defense system. (dogsnaturallymagazine.com)

Squamous Cell Carcinoma (SCC) is the second most common malignant neoplasm in dogs that can develop in a variety of locations. (petmoo.com)
The terms 'epidermoid carcinoma,' 'squamous cell epithelioma,' 'epithelioma spinocellular,' 'spinalioma' and 'prickle cell epithelioma' have all been used in medical circles, but 'squamous cell carcinoma' is the most commonly used terminology. (petmoo.com)
How To Prevent Squamous Cell Carcinoma In Dogs? (petmoo.com)
Prevention is not possible for Squamous cell carcinoma as the causes in dogs is varied. (petmoo.com)

In the present study we investigated Dexa's in vitro effects on the growth of cell proliferation and the induction of apoptosis in canine Achilles tendon cells and chondrocytes. (vin.com)
Cell apoptosis was induced by Dexa, as evidenced by the typical nuclear apoptosis using Hoechst 33258 staining. (vin.com)
Dexa increased the apoptosis of canine tendon cells and chondrocytes in a time-dependent manner. (vin.com)
In addition, culturing with Dexa and the glucocorticoid receptor blocker mifepristone significantly arrested apoptosis of tendon cells and chondrocytes. (vin.com)
Based on our in vitro data, we speculate that in vivo treatment with glucocorticoids may diminish the proliferation of tendon and cartilage cells by increasing apoptosis and suppressing the proliferation. (vin.com)
Overall, the study found that Yunnan Baiyao causes dose and time dependent HSA cell death through initiation of caspase-mediated apoptosis, which supports future studies involving Yunnan Baiyao. (fitzpatrickreferrals.co.uk)

Fortunately, his story made the news and through donations and good will, Max was able to have surgery and treatment with VetStem Cell Therapy. (vetstem.com)
Fortunately for Sherlock, his veterinarian recommended using VetStem Cell Therapy in conjunction with surgery. (vetstem.com)

The PulseNet specimens have no connection other than symbiotic flora, colonization, contamination, or infection by bacteria that at some point years ago were progeny of the same cell. (cdc.gov)
If the lives of this cell appear in 2 specimens sent to PulseNet, connections are revealed across time and space. (cdc.gov)

For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
The aims of this study were to investigate the effect of oviductal cells on in vitro maturation (IVM) of canine oocyte in Tissue Culture Medium 199 (TCM-199) or synthetic oviductal fluid (SOF) supplemented with bovine serum albumin (BSA) or fetal calf serum (FCS) and to compare the maturation rates of oocytes from the diestrus and anestrus stages. (tubitak.gov.tr)
In conclusion, in the oocytes obtained from bitches in diestrus and anestrus supplemented with FCS or BSA in SOF medium without oviductal cells, more positive effects were seen on canine oocyte maturation than with TCM-199 medium supplemented with same protein sources and oviductal cells. (tubitak.gov.tr)

An epithelial cell line derived from a kidney of a normal adult female dog. (bvsalud.org)

Why choose the RVC for your dog's canine stem cell treatment? (rvc.ac.uk)
Max once again recovered well and hasn't required a repeat stem cell treatment since. (vetstem.com)
Sherlock's owner reported that he responded well to his initial stem cell treatment but that shortly after, he injured the cruciate ligament in his left knee. (vetstem.com)

Cell proliferation after treating with Dexa for 2-6 days was quantified by a 2,3-bis{2-methoxy-4-nitro-5-sulfophenyl}-2H-tetrazolium-5-carboxyanilide inner salt assay (XTT). (vin.com)
The results showed that Dexa could inhibit the proliferation of tendon cells and chondrocytes at increasing concentrations (0.1-50 µg/ml) in compared with untreated cells. (vin.com)
They are invasive, the unregulated proliferation of epidermal prickle-squamous cell layers that also show keratinocytic differentiation. (petmoo.com)

In humans, AMH has been shown to be a specific marker of Sertoli cell origin in gonadal tumours. (vin.com)
A recent study from the UK revealed that dogs are experiencing depression from being ignored by their smartphone-consumed humans. (calendar-canada.ca)
Dogs, on the other hand, perceive information at least 25% faster than us humans. (calendar-canada.ca)
The scientists found that not only could the dog recognize her owners smell from the rest, but they found that her brain's pleasure center was activated only when she detected her owners smell, not when she detected other humans' scents. (calendar-canada.ca)
Early in life, puppies develop much faster than humans, but as dogs get older, their aging curve begins to flatten. (sciencenews.org)
Humans and dogs develop primarily cancer of the bladder, whereas rodents develop primarily liver cancer. (cdc.gov)

Previously, intra- and interspecific canine embryos have been constructed by canine SCNT into canine and bovine oocytes, respectively, but this did not result in viable offspring 9 . (nature.com)
We have used polyclonal antisera to the major bovine epidermal desmosome components (greater than 100 kD) in a sensitive assay involving immunoprecipitation of the components from metabolically labeled MDCK cell monolayers to investigate the mechanism of calcium-induced desmosome formation. (rupress.org)

These dogs are commonly labeled "at risk," due to their likelihood of being euthanized or their past history of fighting. (wikipedia.org)
Others, most commonly Sertoli cell tumours (SCT), may present with signs of feminization. (vin.com)
Although both male and female dogs could be affected, this type of cancer commonly occurs in older female canines. (petinsurancequotes.com)
This study demonstrated the in vitro anti-neoplastic properties of CBD on five canine cancer cell lines representative of all three major cancer lineages when used as a single agent, as well as in combination with commonly utilized chemotherapeutics. (wildliferx.com)

It tells you whether all abnormal cells were removed, and whether - or how fast - the cancerous mast cells may spread in the body. (dogsnaturallymagazine.com)
It consists of pills given orally at home by owners, and works by preventing protein metabolism in cancerous cells. (naturalpet.health)

The successful expression of a functional basolateral receptor in MDCK cells opens the way for the characterization of the mechanisms that control targeting and recycling of proteins to the basolateral membrane of epithelial cells. (rupress.org)
MDCK cells, whether cultured in LCM or SCM, were found to synthesize the desmosome protein, DPI and desmosome glycoproteins DGI and DGII/III with identical electrophoretic mobility, and also, where relevant, with similar carbohydrate addition/processing and proteolytic processing. (rupress.org)
The half-lives decreased by a factor of about 7 for DGI and 12 for DGII/III and, consistent with this, MDCK cells labeled for 48 h in SCM had three and six times the amount of DGI and DGII/III, respectively, as cells labeled for 48 h in LCM. (rupress.org)

However, Neu5Gc expression on target cells did not enhance CPV or FPV infection in vitro. (nih.gov)
White blood cells are immune system cells having responsibility to control inflammation, fight infection, clean up the breakdown products of day-to-day cellular function, and more. (thehonestkitchen.com)
And one of the tricky things for the Veterinarian and also in aspect that all guardian should be aware is that often a urinalysis will look just like a urinary infection and so we always need to have this type of cancer in mind when we're dealing with an apparent diagnoses of a urinary tract infection, especially if you have scotty or an obese dog or an elderly dog. (dogcancerblog.com)
It's one of those that guardians look back and wonder if it's should have been caught sooner because and actually was interesting as a lot of dogs with transitional cell carcinoma have a secondary bacterial infection, or secondary urinary tract infection, and that's why they temporarily respond to the antibiotics and then they complete the course of antibiotics and the symptoms recur. (dogcancerblog.com)
If a dog has an elevated white blood cell count , it could mean that there is an infection in the body or it is stressed by metabolic toxins. (vetinfo.com)
An increased lymphocyte count is usually present when an animal has a prolonged illness, such as a bacterial or viral infection that has occurred for a long period of time, or if the dog has certain auto-immune diseases, such as leukemia . (vetinfo.com)
Blood sample from the both epithelial infection and the asymptomatic dogs had been collected for molecular analysis. (fiocruz.br)
White blood cells in your stool are usually a sign that you have an infection or other condition in your digestive system that's causing inflammation. (medlineplus.gov)
Infection can happen from food and contact with dog and cat feces (poop). (medlineplus.gov)

When your vet tests the cells within the lump or lesion, she'll be able to tell you whether an MCT is benign or malignant. (dogsnaturallymagazine.com)

Ferritin is a multimeric protein consisting of heavy and light chains assembled in different tissue-specific ratios, which can protect cells from oxidative stress by storing reactive iron (Fe). (bioone.org)
Stem cells have the ability to reduce pain, inflammation, and minimize the formation of scar tissue. (vetstem.com)

Histamine -A nitrogen-based biochemical which makes blood vessels more permeable to the movements of white blood cells in order for the white blood cells to do their job in defending against invading bacteria, parasites, and viruses. (thehonestkitchen.com)
Photomicrograph of exfoliative vaginal cytologic slide of a bitch during early diestrus, showing two metestrum cells (asterisks), a large intermediate cell, neutrophils, and bacteria. (msdvetmanual.com)
White blood cells, also called leukocytes, help to defend the body against bacteria, viruses and fungi. (vetinfo.com)
The cells will actually engulf bacteria and other materials to keep them from causing problems. (vetinfo.com)

These cells are multipotent, meaning they have the ability to differentiate into several different specialised cell types, such as cartilage cells (chondrocytes), bone cells (osteoblasts) and fat cells (adipocytes). (rvc.ac.uk)

Using immunohistochemistry, AMH has been shown to be a useful marker of immature and neoplastic Sertoli cells in dogs. (vin.com)
The only way to distinguish between B and T cell types is with specialized testing called flow cytometry or immunohistochemistry (IHC). (naturalpet.health)

Political pollsters have been under pressure to make sure their samples include Americans who rely solely on cell phones-and the latest NBC News/Marist polls of Florida, Ohio and Virginia exhibit why. (yahoo.com)
According to the poll, 28 percent of its respondents in Ohio and Florida were cell phone users, compared to 27 percent in Virginia. (yahoo.com)

Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
The effect of oviductal cells on in vitro maturation of canine oocytes" by SİNEM ÖZLEM ENGİNLER, ASİYE İZEM SANDAL et al. (tubitak.gov.tr)

Because the lens is constantly exposed to UV irradiation, we studied its effects on ferritin synthesis and Fe metabolism in cultured lens epithelial cells with and without ascorbic acid (Asc). (bioone.org)
J. Harned , A. M. Grimes , and M. C. McGahan "The Effect of UVB Irradiation on Ferritin Subunit Synthesis, Ferritin Assembly and Fe Metabolism in Cultured Canine Lens Epithelial Cells," Photochemistry and Photobiology 77(4), 440-445, (1 April 2003). (bioone.org)

Junginger J , Schwittlick U , Lemensieck F , Immunohistochemical investigation of Foxp3 expression in the intestine in healthy and diseased dogs . (avma.org)
The objectives of this study was to explore the anti-proliferative and cell death response associated with in vitro treatment of canine cancer cell lines with CBD alone and combination with common chemotherapeutics, as well as investigation into major proliferative pathways (eg, p38, JNK, AKT and mTOR) potentially involved in the response to treatment with CBD. (wildliferx.com)

Over months to years of life the body's cells are exposed to a variety of noxious agents that cause cellular DNA changes ultimately manifesting as cancer. (thehonestkitchen.com)
One of the cancers that you both talk about in the Dog Cancer Survival Guide is transitional cell carcinoma. (dogcancerblog.com)
So, it's a little bit frustrating and quite some tends to be 20/20, but it's a cancer with a lot of treatable option, some dogs depending on the location in the bladder will recommend surgery, but it is a cancer that even if it's non-surgical they can respond very well to chemotherapy. (dogcancerblog.com)
There's a lot of information on transitional cell carcinoma in The Dog Cancer Survival Guide, and I want to thank you both for joining us today. (dogcancerblog.com)
Transitional cell carcinoma (TCC) is a cancer of the transitional epithelial cells of the urinary tract in dogs. (petinsurancequotes.com)
Pending additional research, CBD and other cannabinoids may be utilized as adjuvant therapy for canine cancer patients, but must take into account the current chemotherapeutic protocol with trepidation because of potential drug-drug interactions. (wildliferx.com)
Our scientific model for MCT risk is unique, offering the first cancer-related risk assessment of its kind from a dog DNA company. (embarkvet.com)
However, that does not mean that such therapy has no benefit for our dogs in their journey through cancer. (naturalpet.health)
While investigating the effect of human milk on bacterial adherence to a human lung cancer cell line, we were surprised to discover that the milk killed the cells. (lu.se)

What is the difference between stem cell therapy and platelet rich plasma (PRP)? (rvc.ac.uk)
Aim: To compare the alveolar bone repair process using biomaterial in dogs with and without the incorporation of platelet-rich plasma. (bvsalud.org)
The purpose of the present study was to perform bilateral tooth extractions in dogs and compare the alveolar bone repair process using Bio-gen® (Bioteck) and Genox® (Baumer) with and without the incorporation of platelet-rich plasma. (bvsalud.org)

Dr. Dressler, what are your thoughts on treatment options for transitional cell carcinoma? (dogcancerblog.com)
This study evaluated the in vitro activity of Yunnan Baiyao against three canine HSA cell lines after treatment with increasing concentrations of Yunnan Baiyao (50, 100, 200, 400, 600 and 800 µg mL−1) at 24, 48 and 72 h. (fitzpatrickreferrals.co.uk)
ASC treatment upregulated granulocyte-macrophage colony stimulating factor (GM-CSF) at the gene level, which may contribute to the recruitment of cells that participate in skin repair to the site of injury. (biomedcentral.com)
The overexpression of a single transcription factor in MSCs may promote transdifferentiation into a specific cell lineage, which could then be used for the treatment of some diseases. (biomedcentral.com)

A white blood cell in stool test is used if you have diarrhea that could be caused by inflammation. (medlineplus.gov)
A white blood cell in stool test is used to find out whether diarrhea is caused by conditions that involve inflammation in the digestive system. (medlineplus.gov)
But you may need a white blood cell in stool test and other tests if you have symptoms of diarrhea from inflammation that don't improve after a few days. (medlineplus.gov)

This is a time to recognize and honor the hard work and selfless love that assistance dogs provide day in and day out. (vetstem.com)
These dogs can find anything with digital storage by training them to recognize the scent of TPPO, a chemical that coats memory chips to protect them from overheating. (calendar-canada.ca)

There are a lot of different options and some new chemotherapy options out there for transitional cell carcinoma. (dogcancerblog.com)

The knowledge we have gained from a proven successful track record in stem cell applications in horses has now been applied to canine clients for joint, tendon and ligament injuries. (rvc.ac.uk)
In canine tendon cells and chondrocytes treated with 25 and 50 µg/ml concentration of Dexa the number of condensed apoptotic nuclei was significantly increased. (vin.com)
Our findings suggest that Dexa could be used with caution in dogs with articular or tendon problems. (vin.com)

There are a number of hypothesized that regulating the transgene with a GFAP promoter in a different vectors that transduce cells in the brain in a slightly different viral vector would give rise to a high transgenic expression in the manner (for a review see, e.g. (lu.se)

The body produces mast cells as an inflammatory and histamine response. (dogsnaturallymagazine.com)
Inflammatory bowel disease versus chronic enteropathy in dogs: are they one and the same? (avma.org)
Jergens AE , Schreiner CA , Frank DE , A scoring index for disease activity in canine inflammatory bowel disease . (avma.org)
Canine atopic dermatitis (cAD) is a chronic and recurrent inflammatory and pruritic skin disease in dogs. (mdpi.com)

Department of Cell Biology and Anatomy, Cornell University Medical College, New York 10021. (rupress.org)

All control dogs except one had AMH concentrations ≤ 10 ng/mL. (vin.com)
Dogs with SCT or mixed tumours containing SCT had AMH concentrations higher than 22 ng/mL, significantly higher than AMH concentrations in control dogs (p = 0.0004). (vin.com)
Concentrations between 10 and 22 ng/mL were found in about half of the dogs with non-neoplastic testicular pathologies or with testicular tumours other than SCTs. (vin.com)

In order to further understand the potential use of MSCs to treat dogs with neurological disorders, this study examined the paracrine action of adipose-derived canine MSCs on neuronal and endothelial cell models. (aston.ac.uk)
The culture-expanded MSCs exhibited a MSC phenotype according to plastic adherence, cell morphology, CD profiling and differentiation potential along mesenchymal lineages. (aston.ac.uk)

Throughout the training, inmates receive animal-assisted therapy as well as human-canine bonding. (wikipedia.org)
The inmates train therapy and service dogs as a way to give back to society. (wikipedia.org)
Weekly training sessions led by professional therapy, emotional support, and guide dog trainers, provides the inmates with the skills needed to teach the dogs the necessary skills it takes to assist someone in need. (wikipedia.org)
What are stem cells and how does stem cell therapy work? (rvc.ac.uk)
Whilst we still don't completely understand the underlying mechanisms, current research suggests that the beneficial effects of stem cell therapy are more likely to be derived from their immunomodulatory properties, rather than being truly regenerative, however some degree of regeneration has been shown in some research. (rvc.ac.uk)
PRP is very quick and simple to prepare and therefore cheaper than stem cell therapy, however due to a lack of large studies published it is hard to say how effective PRP is, and it can vary in quality depending on how it is prepared. (rvc.ac.uk)
Are there any negative side effects or risks associated with canine stem cell therapy? (rvc.ac.uk)
As an experienced VetStem provider, Dr. Christiansen recommended stem cell and platelet therapy in conjunction with the surgery to aid Max's healing. (vetstem.com)
VetStem provided a free platelet therapy kit as well as discounted stem cell processing services. (vetstem.com)
Max received surgery on his other knee in addition to stem cells and platelet therapy. (vetstem.com)
The improvement was fantastic after he recieved his stem cell therapy. (veterinarystemcells.com.au)
In the European Union, the use of these treatments has been possible because cell therapy products have been considered medicinal products since 2003, according to legislation through Directive 2003/63/EC [ 7 ]. (biomedcentral.com)
Our decision was stem cell therapy, and not once have we regretted the choice we made. (vetstem.com)
The aim of our research was to determine how immunotherapy changes the proportion of lymphocyte subsets in dog peripheral blood and the levels of cytokines secreted by these cells during therapy. (mdpi.com)

It has been utilized in the veterinary profession to control bleeding in dogs with hemangiosarcoma (HSA) and has been anecdotally reported to prolong survival times in dogs with this neoplasm. (fitzpatrickreferrals.co.uk)
NK cell infiltration is associated with improved overall survival in solid cancers: a systematic review and meta-analysis. (bmj.com)

Mast cells release these chemicals into the body when they are triggered by the immune system. (vetinfo.com)
Mast cells are filled with granules, which are sack-like pockets of biochemicals that help protect the body from invading pathogens (parasites, etc.) and antigens (immune system stimulating substances, like pollen, etc. (thehonestkitchen.com)
White blood cells are part of your immune system . (medlineplus.gov)

The liver, spleen, bone marrow, and lymph nodes are organs where white blood cells are produced and stored. (thehonestkitchen.com)

Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
A factory produces a contaminated product, and the lives of a cell connect a retired person on a limited income to a young adult consuming the same product in a different county. (cdc.gov)

J Cell Biol (1989) 109 (6): 2809-2816. (rupress.org)
J Cell Biol (1987) 105 (5): 2327-2334. (rupress.org)

Our data support a One Health approach to the study of DLBCL, including the advancement of novel therapies of relevance to both canine and human health . (bvsalud.org)

A pilot study to characterize the transcriptomic phenotype of 11 dogs with multicentric BCL yielded two molecular subtypes distinguished on the basis of genes important in oxidative phosphorylation . (bvsalud.org)

Studies of the half-life of metabolically labeled receptor and of the stability of biotinylated cell surface receptor after internalization indicate that transfected CHL performs several rounds of uptake and recycling before it gets degraded. (rupress.org)

Here we report reproducible culture of highly potent TINKs from naturally occurring canine sarcomas for use in modeling the human TME. (bmj.com)
Future studies using canine TINKs will explore therapeutic potential for targeting, manipulating, and transferring these cells in human. (bmj.com)
Can dogs smell human arousal? (calendar-canada.ca)
The relationship between human and dog years changes over time, the scientists found. (sciencenews.org)
A 1-year-old dog corresponds to around 31 human years, and a 4-year-old dog is closer to a 53-year-old human. (sciencenews.org)
We propose a metabolic classification of canine BCL that transcends cell of origin and shows parallels to a similar molecular phenotype in human DLBCL. (bvsalud.org)
However, it has rarely been considered that human milk may also contain substances bioactive toward host cells. (lu.se)
The phrase lives of a cell refers to the independent yet interrelated parts of a human cell including mitochondria, centrioles, and basal bodies that once led independent lives. (cdc.gov)
Our human lives do not depend just on the lives in our individual cells. (cdc.gov)
A contamination in dog food can sicken a dog's human owners, while the dogs remain healthy. (cdc.gov)

Cell dogs often go on to help those in need after finishing their training in the form of a service dog. (wikipedia.org)
During the training process, inmates express they form special bonds with their Cell dog, and the thought of the dogs leaving their side once training is complete can be a challenging experience for many. (wikipedia.org)
However, sometimes, these mast cells can join together and form masses in or under the skin. (embarkvet.com)

Gastrin receptors on isolated canine parietal cells. (jci.org)
Canine parietal cells have specific receptors for gastrin that mediate stimulation of parietal cell function. (jci.org)
Gastrin receptors were undetectable on chief cells, and yet present on another smaller mucosal cell(s). (jci.org)
Transfected cell lines stably express 87,000 surface receptors/cell with a kd = 13 nM. (rupress.org)

PRP has a significant concentration of growth factors that enhance bone formation and mineralization, induce stem cells to differentiate into osteoblasts, diminish bone resorption, promote angiogenesis and produce collagen through the activation of fibroblasts 12-13 . (bvsalud.org)

Donor fibroblasts were obtained from an ear-skin biopsy of a male Afghan hound and cultured for two to five passages (in which fully grown cells are transferred to a new culture dish). (nature.com)
Dogs frequently present to first-opinion practice with skin masses, which may require diagnostic work-up including fine needle aspirate and/or biopsy. (thewebinarvet.com)

Anatomy35

Organisms39

Diseases43

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment42

Psychiatry and Psychology3

Phenomena and Processes42

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science3

Health Care7

Geographicals2

Tumors32

Transitional cell carcinoma in2

Madin-Darby3

Breeds11

Cutaneous3

Clinical9

Mast cell5

Diagnosis3

Mesenchymal stem3

Feline2

Induces Apoptosis1

Tumor13

Tumours in Dogs1

Lymphoma15

Dog's immune2

Squamous Cell Carc4

Apoptosis6

VetStem Cell Therapy2

Specimens2

Oocyte3

Epithelial cell1

Stem cell treatment3

Proliferation3

Humans6

Bovine2

Commonly4

Cancerous2

MDCK3

Infection9

Malignant1

Tissue2

Bacteria4

Cartilage cells1

Immunohistochemistry2

Florida2

Maturation2

Metabolism2

Investigation2

Cancer9

Platelet rich plasma3

Treatment4

Inflammation3

Recognize2

Chemotherapy1

Tendon3

Viral1

Inflammatory4

Anatomy1

Concentrations3

MSCs2

Therapy14

Survival2

Immune system3

Bone marrow1

Adult2

Biol2

Therapies1

Oxidative1

Metabolically labeled1

Human10

Form3

Receptors4

Osteoblasts1

Biopsy2