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  • embryonic stem
  • The Times failed to mention important issues covered during the panel discussion, which include, but are not limited to, the uncontested fact that human embryonic stem cells have never been used successfully in clinical trials in humans and carry significant risks, including immune rejection and tumor formation. (freerepublic.com)
  • A study published in the Jan. 23, 2002, New Scientist reports on research conducted at the University of Minnesota showing that stem cells taken from adult bone marrow have the ability to proliferate extensively in culture and form virtually any tissue in the body _ properties once claimed exclusively for embryonic stem cells. (freerepublic.com)
  • The New York Times echoed that sentiment saying that research using embryonic stem cells and therapeutic cloning using artificially manufactured cloned human embryos is not even close to being perfected, let alone yielding cures (``The Promise of Therapeutic Cloning,'' Jan. 5). (freerepublic.com)
  • Light-sensitive retinal cells grown in laboratory from embryonic stem cells help restore sight to blind mice, this marks a further boost for the fast-moving field of retinal therapy, finds study. (medindia.net)
  • biopsies
  • RS cells in Hodgkin's Lymphoma biopsies specifically expressed the senescence markers and cell cycle inhibitors p21 Cip1 and p16 INK4a and were negative for the proliferation marker Ki-67, suggesting that these cells have ceased to proliferate. (hematopoiesisnews.com)
  • INTESTINAL STEM CELL
  • The authors used modular synthetic hydrogel networks to define the key extracellular matrix (ECM) parameters that govern intestinal stem cell expansion and organoid formation, and showed that separate stages of the process require different mechanical environments and ECM components. (intestinalcellnews.com)
  • vivo
  • The authors found that DNA methyltransferase 3A ( Dnmt3a ) mutations induced hematopoietic stem cell expansion, cooperated with mutations in the FMS-like tyrosine kinase 3 gene ( Flt3 ITD ) and the nucleophosmin gene ( Npm1c ) to induce acute myeloid leukemia in vivo , and promoted resistance to anthracycline chemotherapy. (hematopoiesisnews.com)
  • neurons
  • You can imagine it's pretty difficult to get neurons from individuals, but now we don't have to," said Courtney Kronenthal, spokeswoman for the Coriell Institute for Medical Research, which will store and deliver stem cells to buyers. (sacbee.com)
  • We can get those from skin and blood cells (of someone with Alzheimer's disease) and develop them into neurons. (sacbee.com)
  • Knockout of Sam68 constricted the pool of proliferating NPCs by accelerating their cell cycle exit and differentiation into post-mitotic neurons. (neuralcellnews.com)
  • taxpayer
  • While the Obama administration prepares to dump billions of taxpayer dollars into the controversial and now obsolete embryonic stem cell research, people who have been helped with adult stem cell technology are struggling to pay the bills because of insufficient funding. (womenofgrace.com)
  • Rep. Doug Lamborn (R-Co.) tweeted on Tuesday that the FDA was using federal money to create demand for aborted fetal remains, and that "Taxpayer dollars should not be used to fund this grotesque practice. (catholic.org)
  • dialogue
  • David Ayares, head of research and development at the U.S. division of PPL Therapeutics, said, "This changes the whole dialogue. (californiahealthline.org)
  • To most laypeople-and certainly, to most pro-lifers-her casual manner seems inappropriate for a dialogue about fetal body parts, but for medical professionals accustomed to discussing clinical procedures with clinical language, it's not suspect at all. (slate.com)
  • subsequent
  • The Times' story covering a panel discussion on stem - cell research and its subsequent editorial advocating passage of S-1909/A-2840 had a number of important omissions and inaccuracies. (freerepublic.com)
  • Hematopoietic
  • They also analyzed the possibility of further improving the GvT effect by loading the DCs with peptides of mismatched hematopoietic cell-specific minor histocompatibility antigens. (hematopoiesisnews.com)
  • patients
  • These guidance documents will provide greater transparency for patients, medical professionals, and law enforcement authorities, about the legal status of stem cell treatments in the U.S. (isscr.org)
  • A measure signed into law 3 October in the state of California, U.S., requires clinics to inform patients if they are using stem cell interventions that have not been approved by the Food and Drug Administration (FDA). (isscr.org)
  • To date, more than 350 PD and approximately 100 HD patients have received primary fetal grafts, and so far no contamination has been reported," said Dr. Nikkah. (medindia.net)
  • Hande MP, Balajee AS, Tchirkov A, Wynshaw-Boris A, Lansdorp PM , Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. (cogforlife.org)
  • proliferation
  • The authors showed that the atypical Fat1 cadherin acts as a molecular 'brake' on mitochondrial respiration that regulates vascular smooth muscle cell proliferation after arterial injury. (musclecellnews.com)
  • Von Kobbe C, May A, Grandori C, Bohr VA , Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest. (cogforlife.org)
  • mice
  • Legislators, pro-life groups, and ethicists have condemned a new government contract to obtain human tissue from aborted children for use in medical research and in the creation of "humanized mice. (catholic.org)
  • Washington D.C., (CNA) - The Food and Drug Administration signed a $15,900 contract to acquire human fetal tissue for use on mice on July 25. (catholic.org)
  • The fetal tissue the FDA intends to purchase would be injected into mice with compromised immune systems in order to create a "chimeric animal" with an immune system like that of a human being. (catholic.org)
  • reveal
  • Stochastic simulations and experimental validations reveal Paneth cell-secreted WNT as the key intercellular coupling component linking the circadian clock and cell cycle in enteroids. (intestinalcellnews.com)
  • ethical
  • And even less, really nothing at all, is said about the ethical dilemmas the Nazi research raises. (jaapl.org)
  • The FDA released a statement defending the contract and the research, saying that the agency is "committed to ensuring that its research is conducted responsibly, conforms with all legal requirements, and meets the highest ethical standards," and noting that this type of research is a "very small fraction" of the agencyďż˝ s work. (catholic.org)
  • The ISSCR advocates worldwide for ethical stem cell research and its translation to the clinic. (isscr.org)
  • Vatican
  • And I find it intensely interesting that shortly after Robert Graham's death, the Vatican ordered all his research papers sealed and returned to Rome. (bookbrowse.com)
  • protocol
  • Their research provided a protocol for the isolation and expansion of large numbers of MFDCs that may see future clinical use, said the study authors. (medindia.net)
  • CD34
  • Investigators showed that mixed-lineage leukemia (MLL) fused to murine Af4, highly conserved with human AF4, produced high-titer retrovirus permitting efficient transduction of human CD34 + cells, thereby generating a model of t(4;11) pro-B acute lymphoblastic leukemia that fully recapitulates the immunophenotypic and molecular aspects of the disease. (hematopoiesisnews.com)
  • practice
  • In this senior leadership role, Jane has overseen the implementation of the university's research integrity program aimed at promoting responsible research practice and the development of the mechanism to managing allegations of research misconduct. (publicationethics.org)
  • Based on the technique's success in decontaminating fetal tissue cells transplanted into laboratory animals, the washing technique was subsequently used in clinical practice. (medindia.net)
  • The FDA further defended the use of aborted remains in research, saying the practice "has led to a better understanding of a number of conditions and diseases that affect millions of Americans. (catholic.org)
  • myeloid
  • Furthermore, selective pharmacologic targeting of the gamma isoform of phosphoinositide 3-kinase (PI3Kγ), highly expressed in myeloid cells, restores sensitivity to ICB. (hematopoiesisnews.com)
  • issues
  • We also provide background and current understanding about stem cell science to inform decision makers about key issues affecting science and health. (isscr.org)
  • A treatment such as this becomes especially interesting as we seek parallels with current issues - for example, fetal tissue and embryonic stem cell research, use of individual and population genomic information, and DNA editing. (upenn.edu)
  • Using natural law, Christians can establish common moral ground upon which to engage the secular world in the public square over many moral issues, including sexual ethics, cloning, and stem cell research. (equip.org)
  • 2002
  • The ISSCR was founded in 2002 to foster the exchange of information on stem cell research and now claims more than 4,100 members worldwide. (isscr.org)
  • This article first appeared in the Christian Research Journal , volume 25, number 2 (2002). (equip.org)
  • Investigators
  • Investigators examined the effect of n-3 polyunsaturated fatty acids (PUFAs) and polyphenol (curcumin) combination on leucine-rich repeat-containing G-protein-coupled receptor 5-positive (Lgr5 + ) stem cells during tumor initiation and progression in the colon compared with an n-6 PUFA-enriched control diet. (intestinalcellnews.com)
  • ISSCR
  • The ISSCR commends the U.S. Food and Drug Administration (FDA) for reaffirming its regulatory authority over stem cell biologics and clarifying the criteria that determine which cell-based products fall under its oversight. (isscr.org)
  • In an opinion editorial published today, the president of the ISSCR, Hans Clevers, underscores the importance of fetal tissue research. (isscr.org)
  • The ISSCR joined with more than 60 medical, patient, and academic groups in writing a letter to the U.S. Senate to oppose prohibitions or restrictions that would further impede the use of federal funding for fetal tissue or embryonic stem cell research. (isscr.org)
  • The ISSCR Board writes a letter to the stem cell community regarding travel to the ISSCR 2017 meeting, 14-17 June. (isscr.org)
  • The ISSCR is troubled by the recent decision by the U.S. Department of Health and Human Services to "conduct a comprehensive review of all fetal tissue research. (isscr.org)
  • Whether you are a job seeker or employer, the ISSCR Job Board is the best place to find and post jobs or CVs within the stem cell science community. (isscr.org)
  • Stem Cell Reports is the official journal of the ISSCR and is published by Cell Press. (isscr.org)