• She has worked with xenograft models and many cancer cell lines, and she has expertise in in vitro cell based functional assays and in vivo experiments. (brighttalk.com)
  • In addition to spheroids, collagen-based scaffolds that encourage cell aggregation into tumoroids have been used for immunotherapy applications such as natural killer cell cytotoxicity assays. (genengnews.com)
  • Physiological relevance is a key parameter to improve predictivity of cell-based assays in drug discovery and toxicity testing for compound. (dechema.de)
  • In culture assays it was possible to test human and sheep agent strain combinations that could not be discriminated in animals. (medicalnewstoday.com)
  • The µ-Dish 35-mm Quad from Ibidi GmbH is a four-compartment cell culture dish that can be used for simultaneous assays, guaranteeing high optical quality. (photonics.com)
  • Mutation assays in cultured cells of transgenic rodents constitute, in many ways, viable alternatives to in vivo mutagenicity experiments in the corresponding animals. (mdpi.com)
  • Nuclear runoff assays documented an increased transcriptional rate for the HB-EGF gene in lyso-PC-treated cells. (jci.org)
  • This week (and a half) in Portland Community College's Bioscience Technology Program we continued work with assays, and had guest speakers in Current Topics and Cell Culture. (bio-link.org)
  • He has over 25 years experience in cell biology with specific interests in cell culture technology, neuroscience and stem cell research. (smi-online.co.uk)
  • Scientific advances in cancer cell biology are changing the paradigm in oncology research. (corning.com)
  • Current preclinical GBM models are limited by the lack of a "normal" human microenvironment and the inability of many tumor cell lines to accurately reproduce GBM biology. (brighttalk.com)
  • This text is an indispensable resource for those in or entering the field, including academic research scientists, clinical and biopharmaceutical researchers, undergraduate and graduate students, cell and molecular biology and genetics lab managers, trainees and technicians. (wiley-vch.de)
  • The market for primary cell lines is growing as such cells are thought to be more biologically relevant than other cell lines for studying human and animal biology from basic research to drug discovery. (bccresearch.com)
  • Classical cell biology teaches that exocytosis causes the membrane of exocytic vesicles to disperse into the cell surface and that a cell must later retrieve by molecular sorting whatever membrane components it wishes to keep inside. (pnas.org)
  • The general process of cell culture has been used extensively since the early 1900s for research on tissue growth and development, virus biology, properties of cancer cells, studies relating to aging, genetics, and gene therapy. (encyclopedia.com)
  • The project will provide the opportunity to develop expertise in a wide range of both engineering and cell biology techniques, including microfabrication and lab-on-a-chip techniques, electrochemical sensors, vascular cell isolation and culture, and live-cell imaging. (strath.ac.uk)
  • We propose to apply a systems biology approach to achieve a computational representation of tissue-level physiological responses by integrating empirical data derived from organotypic culture systems with computational models of intracellular pathways to better predict human responses. (osti.gov)
  • 3D cell culture enables cells to grow and interact with their surroundings in all three dimensions, better mimicking the in-vivo conditions in which the cells are naturally present. (smi-online.co.uk)
  • Create a more in vivo-like cell culture to advance your discoveries right from the start. (corning.com)
  • As research demands have become increasingly complex, we have been there every step of the way, creating 3D cell culture solutions that allow you to produce optimal environments for growing cells that exhibit in-vivo like behaviors and functionality. (corning.com)
  • Cells can be isolated from tissues for ex vivo culture in several ways. (wikipedia.org)
  • Quasi Vivo Systems are a series of advanced, interconnected cell culture flow systems, specifically designed to improve cellular phenotypes and human in vivo relevance of in vitro cell culture models. (sciencemag.org)
  • Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry today announced the launch of the BIOSTAT RM TX single-use bioreactor, a new wave mixed system developed specifically for closed, automated expansion of consistent quality cell products such as ex vivo cellular immunotherapies. (news-medical.net)
  • It is becoming increasingly clear that these models mimic cells in vivo at a greater capacity than traditional cell culture. (genengnews.com)
  • Until now it has not been possible to establish progressively growing cultures of these cells in vitro , and cell lines have only been obtained after teratocarcinoma formation in vivo . (nature.com)
  • These cells are able to differentiate either in vitro or after innoculation into a mouse as a tumour in vivo . (nature.com)
  • Culture systems that better mimic the biological milieu are needed to bridge the gap between conventional cultures and complex native in vivo environments. (nature.com)
  • The pluripotency of ES and EG cells can be demonstrated in vitro and in vivo . (pnas.org)
  • Perhaps the most definitive in vivo test of developmental potential would be a demonstrated contribution to all cell lineages in a chimeric animal, but this test is not practical or possible for all species and cannot be done with human cells. (pnas.org)
  • It uses a novel method to create high-density collagen scaffolds with cells embedded, enabling improved cellular interactions that more closely resemble an in vivo environment. (lonza.com)
  • Primary cells are considered by many researchers to be more physiologically similar to in vivo cells. (qiagen.com)
  • In addition, mouse ES cells have been used to generate in vitro cultures of neurons ( 26 ), skeletal muscle ( 27 ), and vascular endothelial cells ( 28 ). (pnas.org)
  • The company's exVive3D™ human liver tissue model is constructed from three basic cellular elements: primary hepatocytes, primary endothelial cells, and primary stellate cells. (genengnews.com)
  • Two key aspects of this process are initial endothelial cell (EC) dysfunction and subsequent phenotypic change and accumulation of smooth muscle cells (SMCs), with inherent disruption in local cell-cell communication. (strath.ac.uk)
  • Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells. (jci.org)
  • In this study, we have found that lyso-PC increased steady state mRNA levels for two smooth muscle/fibroblast-directed growth factors, the A and B chains of PDGF and heparin-binding EGF-like protein (HB-EGF), in cultured human endothelial cells. (jci.org)
  • Lyso-PC did not upregulate the expression of certain other inducible endothelial genes, including E-selectin, IL-8, or monocyte chemoattractant protein-1 in the same cells, in contrast to the coordinate pattern of activation typically observed with other stimuli, such as TNF alpha, bacterial endotoxin, or PMA. (jci.org)
  • Endothelin-1 (ET-1) is a vasoconstrictive peptide of 21 amino acids that was first isolated from porcine vascular endothelial cells. (ahajournals.org)
  • 8 11 12 In human endothelial cells, phorbol esters, activators of PKC, cause a marked and immediate stimulation of ET-1 production, accompanied by induction of preproendothelin mRNA. (ahajournals.org)
  • Join us in February 2019, as we look at the latest developments in the 3D Cell Culture field. (smi-online.co.uk)
  • According to Verified Market Research, Global Primary Cell Culture Market was valued at USD 2.49 Billion in 2018 and is projected to reach USD 5.3 Billion by 2026, growing at a CAGR of 9.84% from 2019 to 2026. (bccresearch.com)
  • A team of scientists led by Prof. Antonella Consiglio from the IDIBELL and the University of Barcelona, and Prof. Angel Raya from the Center of Regenerative Medicine of Barcelona have discovered that defective versions of human brain cells called astrocytes are linked to the buildup of a toxic protein that is one the hallmarks of Parkinson's disease. (news-medical.net)
  • The book is based on lectures, seminars and practical courses in stem cells, tissue engineering, regenerative medicine and 3D cell culture held at the University Natural Resources and Life Sciences Vienna BOKU and the Gottfried Wilhelm Leibniz University Hannover and therefore delivers in a compact and clear way important theoretical as well as practical knowledge to advanced graduate students on cell culture techniques and the current status of research. (powells.com)
  • Naturally based" hydrogels such as Matrigel (made of native extracellular matrix proteins) and collagen (the major extracellular matrix protein) have been explored extensively for applications in three-dimensional tissue culture and regenerative medicine. (sciencemag.org)
  • BD Biosciences: Diverse set of tools for stem cell research. (ucl.ac.uk)
  • Furthermore, disease research areas are expanding to include neurology, stem cell research, cell therapy , and (potentially) tissue engineering. (genengnews.com)
  • As Paul Rabinow does in Making PCR: A Story of Biotechnology (1996), Landecker poses the question of how today's cell manipulations-from cloning techniques to stem cell research and reproductive medicine-have altered our understanding and experience of life. (jhu.edu)
  • Researchers globally are realizing the potential of 3D cell culture for various applications, including testing and discovering new drugs to treat cancer, organ-on-chip models to study the human physiology in an organ specific context, and 3D cell printing to produce organ models. (smi-online.co.uk)
  • From product selection guides to application notes to protocols, our online resource library is available anytime you need to facilitate your cell culture applications. (corning.com)
  • Rely on innovative vessels from Corning for quality and consistency in your cell culture applications. (corning.com)
  • One complication of these blood-derived ingredients is the potential for contamination of the culture with viruses or prions, particularly in medical biotechnology applications. (wikipedia.org)
  • It is available with three different culture chambers (QV500, QV600, and QV900) to support a wide range of applications, including submerged cell culture, coculture, and modeling of air-liquid and liquid-liquid interfaces. (sciencemag.org)
  • Corning™ Untreated 245mm Square Low Profile BioAssay Dishes provide a superior option for applications where cell attachment is not desired. (fishersci.com)
  • Using Nunc Glass Bottom Dishes in your research applications gives you the flexibility to convert your culture device into an imaging device. (fishersci.com)
  • Gibco™ DMEM, Powder, High Glucose, No Sodium Bicarbonate Buffer is used in cell culture processing applications. (fishersci.com)
  • Cell culture is a fundamental technique for a variety of applications. (brighttalk.com)
  • And in therapeutics, 3D cell culture promises to realize several exciting applications, from patient-specific drug-efficacy screening to the manufacturing of bioprinted organs. (genengnews.com)
  • GEN: Are 3D cell culture models as strongly focused as ever on drug safety testing, or are they finding new applications? (genengnews.com)
  • We would argue that 3D cell culture models have been used for many years in basic research and disease modeling, notably in cancer research-this was, after all, one of the original applications of Corning® Matrigel®, a naturally occurring extracellular matrix for us in 3D cell culture. (genengnews.com)
  • Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, Seventh Edition is the updated version of this benchmark text, addressing these recent developments in the field as well as the basic skills and protocols. (wiley-vch.de)
  • Because of the continuing expansion of cell culture, and to keep the bulk of the book to a reasonable size, some specialized protocols are presented as supplementary material online.Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, Seventh Edition provides the most accessible and comprehensive introduction available to the culture and experimental manipulation of animal cells. (wiley-vch.de)
  • Fortunately, bioprinters are becoming commonplace, and the applications that they enable-such as 3D cell cultures-are starting to go mainstream. (genengnews.com)
  • Click here to register for free and to view the entire webinar: http://bit.ly/kosi_136 Since 2008 Kaiser Optical has worked closely with industry leading bioprocessing companies to develop a Raman solution enabled to deliver in situ, real-time measurement to a host of bioprocessing applications including but not limited to cell culture, fermentation, and purification. (environmental-expert.com)
  • Since our first symposium in 2009, the 3D Cell Culture conference series has developed into a 'place to be' for experts active in this field, and will highlight successful applications and newest developments. (dechema.de)
  • Success stories of 3D culture applications will be presented as well as newest technologies and innovations. (dechema.de)
  • Relevant disease models, applications of 3D models in clinic and industry, predictive cell models for compound characterization and enabling technologies will be covered. (dechema.de)
  • This textbook provides an overview on current cell culture techniques, conditions and applications, it specifically focuses on human cell culture. (powells.com)
  • Optimization of cell culture conditions is necessary to ensure that cells are healthy and in optimal condition for downstream applications. (qiagen.com)
  • Corning™ Stripette™ Individually Wrapped Plastic or Paper/Plastic Disposable Polystyrene Serological Pipets are ideal for sterile tissue culture applications, especially while wearing latex gloves, as the wrap reduces static cling. (fishersci.ca)
  • These disposable, space saving containers are specifically designed for optimal plant cell culture applications. (mpbio.com)
  • The 'Recombinant Cell Culture Supplements' market can be divided based on product types and It's sub-type, major applications and Third Party usage area, and important regions. (openpr.com)
  • This Request for Applications (RFA), Papillomavirus In Vitro Cell Culture Systems, is related to the priority area of sexually transmitted diseases. (nih.gov)
  • ELIGIBILITY REQUIREMENTS Applications may be submitted by domestic and foreign for-profit or nonprofit organizations, public and private, such as universities, medical colleges, hospitals, laboratories, units of State and local governments, and eligible agencies of the Federal government having adequate resources or access to resources to support papillomavirus in vitro cell culture research. (nih.gov)
  • Pagina 621 - Jessell TM, Siegel RE, and Fischbach GD (1979) Induction of acetylcholine receptors on cultured skeletal muscle by a factor extracted from brain and spinal cord. (google.it)
  • This test is intended for tissue samples that do not have any accompanying cytogenetic test order (e.g. chromosome analysis or microarray analysis) but needs to be cultured for other molecular genetic or biochemical testing (e.g. (nationwidechildrens.org)
  • Wide-ranging and highly practical, Human Cell Culture, Second Edition, provides novice and experienced researchers alike with a detailed, step-by-step guide to successful culture human cells today. (springer.com)
  • Today, during the 85thth General Session of the International Association for Dental Research, a team of researchers from the Institute of Medical Science, the University of Tokyo (Japan), reports on a new technique for culturing cells that have the capacity to produce enamel. (eurekalert.org)
  • UPM launches GrowDex-T - a new hydrogel offering researchers exceptional imaging properties for visualization of cells in 3D. (news-medical.net)
  • Although most scientists concede that standard cell culture materials (tissue culture plastic and glass) do a poor job of recapitulating native cellular milieus, there is currently a knowledge barrier for many researchers in regard to the application of hydrogels for cell culture. (nature.com)
  • Authoritative and cutting-edge, Protocols for Neural Cell Culture, Fourth Edition continues the previous editions' tradition of exceptional quality and thorough coverage in tissue culture protocols for today's neuroscience in order to inspire researchers in the field to further explore this imperative area of study. (springer.com)
  • With the increasing incidence of neurodegenerative disorders such as Alzheimer's disease, multiple sclerosis, and Parkinson's disease, researchers are testing 3D cellular models that could be superior to animal studies because the cells are derived from humans instead of rodents. (genengnews.com)
  • Researchers are now bridging the gap between natural and synthetic gels by combining well-characterized synthetic materials with biomimetic cues to support physiologically relevant cell-gel interactions (see the figure). (sciencemag.org)
  • A Spinner is a type of bioreactor which features an impeller, stirrer or similar device to agitate the contents (usually a mixture of cells, medium and products like proteins that can be harvested). (wikipedia.org)
  • There have been some breakthroughs on 1, last I heard a group had shown you can just culture with modified proteins to induce pluripotency. (slashdot.org)
  • Consolidating and expanding current, fundamental notions of virology and animal cell cultivation, this practical reference examines the development of insect cell culture techniques for the production of recombinant proteins and insect pathogenic viruses. (routledge.com)
  • One simple method to detect maintained adherence of cells is the staining of attached cells with crystal violet dye, which binds to proteins and DNA. (chemie.de)
  • Physiological processes are guided by interactions between cells and their extracellular matrix, the proteins and polysaccacharides that cells secrete into their environment to support tissue structure and survival. (sciencemag.org)
  • The advantages of synthetic gels include their consistent composition and predictable manipulation of properties, but they lack functional sites to interact with soluble or cell-surface proteins. (sciencemag.org)
  • The second approach explored how the kinetics of amperometric spikes changed in intact cells while stimulus patterns varied ( 8 ), or in permeabilized cells while they overexpressed proteins involved in exo- and endocytosis ( 9 ). (pnas.org)
  • d) repeating steps (b) and (c) as necessary to produce extracellular matrix proteins in the three dimensional stromal culture. (google.com)
  • The effects of these agents on renin mRNA were examined in rabbit and rat proximal tubular cells in primary culture with the use of an S 1 nuclease protection assay. (ahajournals.org)
  • This study, reported in the journal Science, duplicated and extended results of the animal experiments in a neural cell culture assay. (medicalnewstoday.com)
  • In the first, exocytosis of single granules was detected as step increases in membrane capacitance, an assay of cell surface area. (pnas.org)
  • Furthermore, we highlight representative studies in which the Big Blue ® mouse cell culture model and the λ Select cII assay have been used for mutagenicity testing of diverse carcinogens. (mdpi.com)
  • Network with industry experts, gain insight into how the pharmaceutical industry is utilizing 3D Cell Culture technologies to enhance research and development, discuss the potential for novel in-vitro cell culture models to replace animal models, and discover novel 3D cell culture systems, organ-on-chip, 3D imaging of organoids and other technologies in development. (smi-online.co.uk)
  • 2D cell culture has had an extraordinary place in cell culture history and will remain a viable cell culture model for many uses. (corning.com)
  • Due to strict regulatory demands [ 18 , 19 ], the development of a suitable storage method will be essential to enable the transportation of viable cell constructs from centralized laboratories to operating theatres [ 18 ]. (hindawi.com)
  • Professor Przyborski is developing new and innovative ways to manage the growth and function of cultured cells. (smi-online.co.uk)
  • however, only the white cells are capable of growth in culture. (wikipedia.org)
  • Alternatively, pieces of tissue can be placed in growth media, and the cells that grow out are available for culture. (wikipedia.org)
  • Aside from temperature and gas mixture, the most commonly varied factor in culture systems is the cell growth medium. (wikipedia.org)
  • In addition, the third floor culture room is equipped with one lighted incubation shaker and a Coy gloveless anaerobic chamber which was converted into a light chamber (owned by the Martin lab) for the growth of photosynthetic organisms. (concordia.ca)
  • The New Brunswick Innova 4430 incubation shakers are used for the growth of microbial cultures in liquid media. (concordia.ca)
  • Tissue-culture (TC) treated for optimum attachment and growth of anchorage-dependent cells. (fishersci.com)
  • Used in the growth of neuronal cells from hippocampus, cortex and otregions of the brain. (fishersci.com)
  • Cell culture is set to see huge increases in growth including the recent advances in techniques such as 3D cell culture. (smi-online.co.uk)
  • The global market for 3D cell cultures is poised for explosive growth. (genengnews.com)
  • How do I know the minimum of cells for a specific cell line that give a quick entry into log phase growth? (physicsforums.com)
  • Plate different dilutions of your cell line and see were the cut off point is, usually theres a treshold were the cells are suddenly to sparsely plated to give rise to normal growth. (physicsforums.com)
  • The Ph+ feature avoids any meniscus effect and facilitates homogenous cell growth. (photonics.com)
  • 2. The cell growth apparatus according to claim 1, wherein each compartment comprises opposing gas permeable, liquid impermeable surfaces. (freepatentsonline.com)
  • 3. The cell growth apparatus according to claim 1, wherein each compartment comprises a plurality of gas permeable, liquid impermeable surfaces which form the expandable walls of the compartment. (freepatentsonline.com)
  • 4. The cell growth apparatus according to claim 1, wherein the gas permeable, liquid impermeable surfaces are selected from the group consisting of polystyrene, polypropylene, polyethylene, polycarbonate, silicone rubber, fluoroethylenepropylene copolymer and a combination thereof. (freepatentsonline.com)
  • 6. The cell growth apparatus according to claim 1, wherein the spacer material is selected from the group consisting of a woven mesh and a planar sheet comprising protruding support features. (freepatentsonline.com)
  • 7. The cell growth apparatus according to claim 1, further comprising a support structure external to the compartments. (freepatentsonline.com)
  • 8. The cell growth apparatus according to claim 7, wherein the support structure comprises a compartment frame perimetrically surrounding each of the compartments for supporting the gas permeable, liquid impermeable surfaces. (freepatentsonline.com)
  • 9. The cell growth apparatus according to claim 7, wherein the support structure comprises a top platen and a bottom platen confining the plurality of compartments there-between. (freepatentsonline.com)
  • 10. The cell growth apparatus according to claim 7, wherein the support structure is optically transparent. (freepatentsonline.com)
  • 11. The cell growth apparatus according to claim 9, wherein the support structure further comprises at least one rod inserted through a supported hole in at least one of the compartments and attached to the top platen and the bottom platen. (freepatentsonline.com)
  • 12. The cell growth apparatus according to claim 10, wherein the rod is telescoping to form an expandable support structure. (freepatentsonline.com)
  • 13. The cell growth apparatus according to claim 1, wherein the interconnecting passageway comprises ports in the gas permeable, liquid impermeable surface of each compartment. (freepatentsonline.com)
  • This protocol describes a quick and reliable screening method that is suitable for the examination of the impact of chemotherapeutics or other compounds on cell survival and growth inhibition. (chemie.de)
  • From cell preparation and growth to investigation and analysis, our comprehensive portfolio provides the quality and consistency to ensure the validity of your results. (sigmaaldrich.com)
  • Primary Bronchial/Tracheal Epithelial Cells, Normal, Human, ATCC PCS-300-010), supplement Airway Epithelial Cell Basal Medium with the Bronchial Epithelial Cell Growth Kit (ATCC PCS-300-040). (atcc.org)
  • Different cell types vary greatly with respect to their growth behavior and nutritional requirements. (qiagen.com)
  • Growth, Nutrition, and Metabolism of Cells in Culture, Volume 1, summarizes the state of knowledge of the growth, nutrition, and metabolism of various types of cell cultures. (elsevier.com)
  • Dispersed cells are then transferred to a suitable growth medium and allowed to attach to the surface of culture flasks. (encyclopedia.com)
  • Cell culture requires careful attention to the growth medium to ensure cells are given all the components they require to grow. (encyclopedia.com)
  • Often the culture medium requires growth factors or hormones to stimulate growth. (encyclopedia.com)
  • Media used to propagate cells are rich in nutrients and, therefore, support growth of a multitude of organisms. (encyclopedia.com)
  • Topics include cellular organization at the molecular level, fibrogenesis in tissue culture, effect of radiation on the growth of isolated cells, and irradiation of the selected parts of the cell. (elsevier.com)
  • Corning™ Falcon™ Tissue Culture Treated Flasks features vacuum-gas plasma tissue culture treatment to ensure consistent growth surface. (fishersci.ca)
  • Designed to improve usability while maintaining the same environment for cell growth as previous designs. (fishersci.ca)
  • Designed to support cell culture growth and biomanufacturing processes. (fishersci.ca)
  • Resuspend the cells in an appropriate volume of prewarmed growth medium. (bio-medicine.org)
  • The volume and the dry weight of a Tetrahymena cell are determined by the particular medium and the growth temperature. (biomedsearch.com)
  • Large cells are seen in concentrated media and at low growth temperatures resulting in cell volumes up to 17,000 microns 3, whereas starving cells decrease gradually towards 700 microns 3 or even smaller sizes. (biomedsearch.com)
  • Cell growth kinetics, division asymmetry and volume control at division in the marine dinoflagellate. (biomedsearch.com)
  • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. (google.it)
  • All plant cell cultures in the PCCL are categorized into three levels of growth, High , Medium and Low . (umass.edu)
  • In the absence of the latter signal, the T cell makes only a partial response and, more importantly, enters an unresponsive state known as clonal anergy in which the T cell is incapable of producing its own growth hormone, interleukin-2, on restimulation. (sciencemag.org)
  • If cultured amniocytes will be used to perform fetal molecular genetic testing, submission of a maternal blood sample (4 mL in EDTA tube) is highly recommended to perform maternal cell contamination study. (nationwidechildrens.org)
  • Future Meat does not use animal serum (the liquid part of blood) in its process (some start-ups growing cultured beef, for example, began by using fetal bovine serum, a byproduct of the livestock industry, although they have since claimed to have validated animal-free alternatives). (foodnavigator.com)
  • 8 11 The isolated glomeruli were then cultured in RPMI 1640 medium containing 20% fetal calf serum (FCS) and antibiotics. (ahajournals.org)
  • To create tissue-specific structures and function in vitro, cell models have to be translated into the third dimension. (dechema.de)
  • This will provide novel mechanistic insights into cardiovascular disease and a well-characterised in vitro model of vascular cell-cell communication suitable for upscaling into an array format for multiplexed, label-free drug screening. (strath.ac.uk)
  • The plan is to release hybrid products combining plant-based and cell based meat in 2021 and a second line of 100% cultured ground meat products suitable for things like burgers and nuggets at a cost of " less than $10 per pound ​" by 2022 (current small-scale production costs are c. $150/lb for chicken and $200/lb for beef). (foodnavigator.com)
  • Although the simplicity of these platforms is attractive, cells cultured in these environments tend to display aberrant behaviors: flattened shape, abnormal polarization, altered response to pharmaceutical reagents, and loss of differentiated phenotype ( Fig. 1 ). (nature.com)
  • The subdivisions enable up to four parallel, individual experiments in one single dish, which saves time and decreases experimental costs by reducing cell numbers and the amount of reagents needed. (photonics.com)
  • cellTRAY forms the basis for lab-on-a-chip technology as it provides the means to automatically dispense and treat cells continually with reagents and cell culture media. (nsti.org)
  • Schwann cells in peripheral nerves receive molecular signals from axons to coordinate the process of myelination. (nih.gov)
  • Our current understanding at the molecular level of this modulatory process and its relevance to T cell tolerance are reviewed. (sciencemag.org)