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  • HSCTs
  • Candidates for HSCTs include pediatric cases where the patient has an inborn defect such as severe combined immunodeficiency or congenital neutropenia with defective stem cells, and also children or adults with aplastic anemia who have lost their stem cells after birth. (wikipedia.org)
  • tissue
  • Billingham RE and Brent L (1954) Quantitative studies of tissue transplantation immunity. (springer.com)
  • A lab technician examines the surface of the sample tissue cells to identify the proteins that give everyone his or her own unique tissue type, called human leukocyte antigens (HLAs). (lls.org)
  • As a result, many researchers have focused on adult stem cells , or stem cells isolated from adult humans that can be transplanted into damaged tissue. (wikipedia.org)
  • Once these MSCs are ready for re-implanation, they are usually transferred with growth factors to allow for continued cell growth and engraftment to the damaged tissue. (wikipedia.org)
  • The National Organ, Tissue and Cell Transplantation Policy is a policy that was formulated by the Surgical and Emergency Services Unit of the Medical Services Development Section, Medical Development Division of the Malaysian Ministry of Health in June 2007. (wikipedia.org)
  • It is also responsible for getting more people to pledge and at the same time act as the registrar for organ, tissue and cells donation in Malaysia. (wikipedia.org)
  • Research into new treatments for spinal cord injuries includes stem cell implantation, engineered materials for tissue support, epidural spinal stimulation, and wearable robotic exoskeletons. (wikipedia.org)
  • The damage can also be divided into primary and secondary injury: the cell death that occurs immediately in the original injury, and biochemical cascades that are initiated by the original insult and cause further tissue damage. (wikipedia.org)
  • An advantage of using teleost fish over other animals, such as pigs, in the studies of diabetes mellitus is that its endocrine cells are separated from the pancreatic exocrine tissue and can be easily isolated and harvested. (wikipedia.org)
  • radiation
  • Ionizing radiation kills lymphoid cells while leaving other tissues of the body intact, and this eliminates immune function. (wikipedia.org)
  • mesenchymal stem
  • Recent research demonstrates that articular cartilage may be able to be repaired via percutaneous introduction of mesenchymal stem cells (MSC's). (wikipedia.org)
  • As an example, a PubMed search for the year 1999 reveals about 90 papers published under the MESH heading of "Mesenchymal Stem Cells", the same search ran for the year 2007 reveals more than 4,000 entries. (wikipedia.org)
  • Until recently, the use of cultured mesenchymal stem cells to regenerate cartilage has been primarily in research with animal models. (wikipedia.org)
  • While the use of cultured mesenchymal stem cells has shown promising results, a more recent study using uncultured MSC's has resulted in full thickness, histologically confirmed hyaline cartilage regrowth. (wikipedia.org)
  • organ
  • Many approaches which have proven successful in rodent models of solid organ or cellular transplantation have not translated well to large animals or humans. (springer.com)
  • Its main objective is to spread correct information and increase awareness on organ donation and transplantation in Malaysia. (wikipedia.org)
  • The NTRC also collaborate with various NGOs, religious bodies, students' association, corporate bodies as well as the media to spread information on organ donation and transplantation to the public. (wikipedia.org)
  • embryonic stem
  • The majority of research involving genetically modified mammals involves mice with attempts to produce knockout animals in other mammalian species limited by the inability to derive and stably culture embryonic stem cells. (wikipedia.org)
  • lesion
  • The knee microfracture surgery technique popularized by Steadman relies on the release of these cells into a cartilage lesion to initiate fibrocartilage repair in osteochondral defects. (wikipedia.org)
  • involves
  • This often involves the analysis of antiserum samples that contain specific antibodies against the immunizing antigen, and blood lymphocytes from lymphoid organs for examination of T cell-mediated responses. (wikipedia.org)