Cell AgingCell CycleCell Line, TumorCell ProliferationCell Cycle ProteinsCell DivisionCyclin-Dependent Kinase Inhibitor p16Signal TransductionTumor Suppressor Protein p53Cells, CulturedCyclin-Dependent Kinase Inhibitor p21Tumor Cells, CulturedMice, Inbred C57BLTelomereApoptosisCell Linebeta-GalactosidaseRNA, MessengerCell DifferentiationNeoplasms, ExperimentalTransfectionAging, PrematureNeoplasmsTumor BurdenMice, KnockoutTelomeraseCell Cycle CheckpointsGene Expression Regulation, NeoplasticRetinoblastoma ProteinNeovascularization, PathologicMice, NudeDNA DamageFibroblastsBiological ProcessesTime FactorsFibrosarcomaAgingNeoplasm TransplantationMolecular Sequence DataMammary Neoplasms, ExperimentalTumor Markers, BiologicalNeoplasm MetastasisImmunohistochemistryCell SurvivalCell Transformation, NeoplasticTumor MicroenvironmentFlow CytometryTelomere ShorteningG1 PhaseCoculture TechniquesTumor Suppressor ProteinsAntineoplastic AgentsBlotting, WesternXenograft Model Antitumor AssaysRNA, Small InterferingDown-RegulationMice, Inbred BALB CTransplantation, HeterologousReverse Transcriptase Polymerase Chain ReactionMelanoma, ExperimentalTumor Necrosis Factor-alphaAdenocarcinomaDNA-Binding ProteinsMitosisPhosphorylationBreast NeoplasmsUp-RegulationReactive Oxygen SpeciesCell MovementGene Expression RegulationCyclinsMice, SCIDOxidative StressRNA InterferencePhenotypeEndothelial CellsS PhaseGenes, Tumor SuppressorDose-Response Relationship, DrugMutationLung NeoplasmsNeoplasm ProteinsG2 PhaseTOR Serine-Threonine KinasesHistonesDisease ProgressionCyclin-Dependent Kinase Inhibitor p27Protein-Serine-Threonine KinasesCarcinoma, Ehrlich TumorBrain NeoplasmsNeoplasm InvasivenessMice, TransgenicWilms TumorModels, BiologicalBase SequenceTranscription FactorsStem CellsColonic NeoplasmsAntigens, NeoplasmG2 Phase Cell Cycle Checkpoints