Cell underwent nucleus. Medical search. Frequent questions

Cell cycle analysis showed a significant increase in the accumulation of KSO-SFE-treated cells at sub-G1 phase, indicating the induction of apoptosis by KSO-SFE. (hindawi.com)
And macrophages and CD8 + T cells were harvested for apoptosis analysis by FCM after 2 days of co-cultures. (medsci.org)
FCM analysis found that human NP cells with increased FasL expression resulted in significantly increased apoptosis ratio of macrophages and CD8 + T cells. (medsci.org)
The ability of E2F-1 to prompt apoptosis in DNA damaged cells coincides with enhanced PRMT1 methylation. (embl.de)
A diagram of the synthesis of degradable nanocapsules into cell nuclei to induce apoptosis, or programmed cell death, in cancer cells. (understandingnano.com)
There is mounting experimental evidence that NF- kB is activated during tumorigenesis in different tissues, and that NF-kB is critically important for cell protection against apoptosis induced by different treatments including chemotherapeutic drugs and gamma-irradiation. (dtic.mil)
The released NF-kB factors then translocate to the nucleus and activate kB-responsive genes involved in cell growth, apoptosis, and metastasis. (dtic.mil)
We also studied whether IKK blockage induces apoptosis andor inhibits PC cell growth. (dtic.mil)
When DNA becomes damaged, p53 helps determine whether the DNA will be repaired or the cell will self-destruct ( undergo apoptosis ). (medlineplus.gov)
While some assays utilize antibodies to study cell health, proliferation, cell cycle or apoptosis, other types of experiments can rely on non-antibody based methods of assessment, often called non-antibody chemical probes. (biolegend.com)
Cellular division for any cell type is dependent on the inherent function, location and the response of cells to repair, apoptosis, or death. (biolegend.com)

Subsequently, clathrins from the host cell lead to endocytosis of the virus. (medscape.com)
Subsequently, the conjugating ciliates pull apart and their zygotic nuclei divide repeatedly to create both types of nuclei. (fsu.edu)
The patient subsequently underwent gall bladder removal surgery. (cellimagelibrary.org)
This unstable nucleus subsequently undergoes essentially instantaneous fission to release 2.4 MeV of kinetic energy in the form of a pair of 7Li3+ and 4He2+ ions, which are confined to the volume of about one cell. (umsystem.edu)

Keratin also protects epithelial cells from damage or stress. (wikipedia.org)
They are also present in epithelial cells in general. (wikipedia.org)
For example, mouse thymic epithelial cells react with antibodies for keratin 5, keratin 8, and keratin 14. (wikipedia.org)
These antibodies are used as fluorescent markers to distinguish subsets of mouse thymic epithelial cells in genetic studies of the thymus . (wikipedia.org)
We already knew that this pathway plays a key role in regulating cell survival in epithelial tissue, but we were surprised to observe such protective dynamics between cells, " comments Romain Levayer, Head of the Cell Death and Epithelial Homeostasis Unit at the Institut Pasteur and last author of the study. (pasteur.fr)
The scientists' research also shows that inhibiting this protective mechanism has a drastic effect on epithelial tissue: cell elimination becomes random and neighboring cells can be eliminated simultaneously, leading to repeated losses of connectivity. (pasteur.fr)
The elimination of groups of neighboring cells is never observed in epithelial tissue in normal conditions, when the EGFR-ERK pathway is not deliberately inhibited, even if a large number of cells are eliminated. (pasteur.fr)
By using a new optogenetic tool that can control cell death in time and space and bypass the protective mechanism, the scientists confirmed that epithelial integrity was compromised when neighboring cells were eliminated simultaneously. (pasteur.fr)
Surprisingly, epithelial tissue is highly sensitive to the spatial distribution of eliminated cells. (pasteur.fr)
explains Léo Valon, a scientist in the Cell Death and Epithelial Homeostasis Unit at the Institut Pasteur and first author of the study. (pasteur.fr)
Histologically, it shows sheets of polyhedral epithelial cells with deep eosinophilic cytoplasm and prominent nuclei. (oldcitypublishing.com)
The duct (clear zone at center) is lined by highly polarized epithelial cells with dark nuclei at the base. (cellimagelibrary.org)
Large cell carcinoma arises from epithelial cells that line the lungs. (medlineplus.gov)

14 , 15 HIF-1 and HIF-2 mediate adaptive responses to hypoxia by inducing the transcription of genes associated with erythropoiesis, glycolytic metabolism, cell survival and angiogenesis. (haematologica.org)
The total chromosomal content of a cell involves approximately 105 genes in a specialized macromolecule of deoxyribonucleic acid (DNA). (cdc.gov)
Cancers occur when genetic mutations build up in critical genes, specifically those that control cell growth and division (proliferation) or the repair of damaged DNA. (medlineplus.gov)
Somatic mutations in many different genes have been found in lung cancer cells. (medlineplus.gov)
The EGFR and KRAS genes each provide instructions for making a protein that is embedded within the cell membrane. (medlineplus.gov)

Summary: Astrocytoma, or pituicytoma, of the posterior pituitary is a relatively rare entity consisting of poorly characterized glial tumor cells. (ajnr.org)
Tumor cells invade through extracellular matrices by forming actin-rich structures called invadopodia, which contain the transmembrane matrix metalloproteinase MT1-MMP. (scivee.tv)
Globules of amyloid like material among tumor cells which undergoes calcification are evident. (oldcitypublishing.com)
12 It is well established that hypoxia is an important selective force in the evolution of tumor cells, 13 and elevated expression of the hypoxia-inducible transcription factors HIF-1 and HIF-2 has been documented in several human cancers. (haematologica.org)
Delivering a large protein complex such as apoptin to the innermost compartment of tumor cells was a challenge, but the reversible polymer encapsulation strategy was very effective in protecting and escorting the cargo in its functional form," said Muxun Zhao, lead author of the research and a graduate student in chemical and biomolecular engineering at UCLA. (understandingnano.com)

Electrons are emitted by the krypton nuclei when they undergo beta decay. (aps.org)
The cell contains a small amount of gaseous krypton-83, a radioactive isotope that produces electrons as its nuclei undergo beta decay. (aps.org)
Essentially, the plasma is confined in a magnetic bottle, since its component charged nuclei and electrons tend to follow the field of magnetic force, which can be so arranged that the lines of force occupy a prescribed region and are thus centralised to a particular volume. (scitizen.com)
The cell contains a small amount of metastable krypton-83 gas, a radioactive isotope that spews out electrons as its nucleus undergoes radioactive decay. (washington.edu)

[ 4 ] High levels of M1 protein, which is encoded by an alternative splicing of the segment 6 of the viral genome, induces genome segments to be exported from the nucleus of the virion through nuclear export protein (NEP protein). (medscape.com)
Vacuolated cells show a striking phenotype of a large perinuclear vacuole (nuclear associated vacuole, NAV) that is distinct from vesicles observed by treatment with an autophagy-inducing agent. (nih.gov)
Treatment with S. occidentalis extracts and light induces an intense lamin A/C signal at the junction of a nuclear vacuole and the nucleus. (nih.gov)
Further study of S. occidentalis extracts and vacuolation provide chemical tools that may contribute to the understanding of nuclear envelope organization and human cell biology. (nih.gov)
nuclear associated vacuole (NAV), nucleus. (nih.gov)
Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an individual, membrane-bound cell. (scivee.tv)
It is, however, important to differentiate between the nuclear cycles that result in polyploid nuclei and those that produce polytene nuclei, because these two terms of the nuclear types are often used indiscriminately in the literature. (scielo.br)
In such a modified nuclear cycle, the chromatin duplicates its DNA content during the G 1 and S stages, but, instead of passing to the G 2 stage, the nucleus initiates a new G 1 phase, thus starting a new cycle of chromatin duplication. (scielo.br)
The endomitotic cycle (endomitosis) starts with a normal prophase (endoprophase), after which the chromosome contracts further (endometaphase), their sister chromatids separate from each other (endoanaphase) and decondense to assume the interphase nuclear structure, resulting in polyploid cells, with double the chromosome number (endopolyploidy) at the end of each cycle. (scielo.br)
The essential difference between endomitosis and the normal cell cycle is the absence of nuclear membrane dissolution in endomitosis, with the whole cycle occurring inside the nucleus. (scielo.br)
In cells characterized by a high rate of protein synthesis and hence by the need for many ribosomes, the nucleolus can occupy 20-25% of nuclear volume (3-5 micron diameter in a 20-micron cell), mostly comprised of the granular component. (nanomedicine.com)
In nuclei having a centrally located nucleolus, the nuclear envelope is folded to form a nucleolar canal that is in direct contact with the nucleolus. (nanomedicine.com)
One of the central anti-apoptotic pathways in cells is mediated by NF-kB nuclear factor kappa-B transcription factors. (dtic.mil)
A DNA virus that enters a host cell needs to find an appropriate nuclear zip code to successfully express, replicate, and persist over long time," said Majumder, who is also an assistant professor in the Department of Oncology at UW. (uwhealth.org)
In addition, nuclear factor κB (NF‑κB), c‑Jun N‑terminal kinase (JNK), extracellular signal‑regulated kinases and p38 mitogen‑activated protein kinase inhibitors and TNF‑α were used to determine the molecular mechanism of autophagy during the inflammatory conditions, and only the NF‑κB and JNK inhibitor were found to enhance the autophagy of rat NP cells. (spandidos-publications.com)

S. occidentalis (Caprifoliaceae) extracts are cytotoxic, and, strikingly, treated cells undergo light-dependent vacuolation near the nucleus. (nih.gov)
C) Ultrathin sections of a Hep2 cell with a typical inclusion of cowpox virus detected near the nucleus. (cdc.gov)

Induced pluripotent stem cells (iPSCs) hold great potential for the modelling of these diseases or as potential therapeutic agents. (nature.com)

Laboratory tests showed leukocytosis (20.79 × 10 9 /L), moderate anemia (69 g/L), increased percent of neutrophils (91.6%), increased C-reactive protein (CRP) (80.90 mg/L), procalcitonin (PCT) (5.87 ng/ml) and erythrocyte sedimentation rate (ESR) (106.0 mm/h) level, and mild hypoalbuminemia (31.0 g/L). Stool routine revealed Leukocyte ++++/HP, pus cell ++++/HP, stool blood was positive. (frontiersin.org)
Using protein-sensitive fluorescent markers, the research team revealed that when a cell dies, the EGFR-ERK pathway - a cell activation signaling pathway known for its involvement in the regulation of cell survival - is temporarily activated in the neighboring cells. (pasteur.fr)
BRAF is a protein kinase and part of the MAP kinase signalling cascade which involves transduction of a growth signal from the cell membrane to the nucleus via a chain of protein kinases and is responsible for cellular proliferation and survival. (hindawi.com)
There were foci of eosinophilia, stellate cytoplasm, and occasional gemistocytic morphology, and many cells were positive for glial fibrillary acidic protein (GFAP). (ajnr.org)
Results Strong hypoxia-inducible factor-2 protein expression was detected in CD138 + multiple myeloma plasma cells in patients' biopsy specimens. (haematologica.org)
Possibly, the abnormal huntingtin protein undergoes proteolysis and is then transported to the nucleus, where it undergoes aggregation. (medscape.com)
Transport to the nucleus may involve specific protein-to-protein interactions that occur in certain cell types only, possibly explaining the selective neuronal vulnerability present in patients with HD. (medscape.com)
In a new study, published online Feb. 1 in the peer-reviewed journal Nano Today, a group led by Yi Tang, a professor of chemical and biomolecular engineering and a member of the California NanoSystems Institute at UCLA, reports developing tiny shells composed of a water-soluble polymer that safely deliver a protein complex to the nucleus of cancer cells to induce their death. (understandingnano.com)
The cell-destroying material, apoptin, is a protein complex derived from an anemia virus in birds. (understandingnano.com)
This protein cargo accumulates in the nucleus of cancer cells and signals to the cell to undergo programmed self-destruction. (understandingnano.com)
The TP53 gene provides instructions for making a protein, called p53, that is located in the nucleus of cells throughout the body, where it attaches (binds) directly to DNA. (medlineplus.gov)
The protein regulates cell growth and division by monitoring DNA damage. (medlineplus.gov)
The altered protein cannot regulate cell proliferation effectively and allows DNA damage to accumulate in cells. (medlineplus.gov)
HT29-Lucia™ AhR cells are engineered from the human HT-29 colon adenocarcinoma cell line for the study of the aryl hydrocarbon receptor (AhR) genomic signaling induction (see details), by monitoring the activity of the Lucia luciferase reporter protein. (invivogen.com)
This 58-residue (6.5 kDa) basic (pI ¼ 10.5) isoelectric point of BPTI, with phosphate as the salting-out protein has long been thought to undergo self-association. (lu.se)
Altered responsiveness to co- oup the nucleus accumbens reflect the behavioral approaches that incorporate caine and increased immobility in the forced swim test associated with elevated cAMP response ele- memory of associations between the extinction-like processes may have effi- ment binding protein in nucleus accumbens. (lu.se)

Cells that are eukaryote in nature divide through the process of mitosis. (differencebetween.net)
In other words, mitosis divides the cell into two daughter nuclei while binary fission divides the cell to form two duplicate cells. (differencebetween.net)
Mitosis commonly occurs in somatic cells of multicellular organisms. (differencebetween.net)
For mitosis, cells undergo a series of stages in order for them to divide into daughter nuclei. (differencebetween.net)
During mitosis, a lot of changes happen to the organelles of the cell. (differencebetween.net)
The whole idea of cell division which involves either mitosis or binary fission is a very particular matter. (differencebetween.net)
3.Mitosis has stages of cell division. (differencebetween.net)
A cell undergoing mitosis thus has no nucleolus and synthesizes no rRNA. (nanomedicine.com)
G 2 is a checkpoint stage of interphase where the cell has two sets of dsDNA and must commit to mitosis. (biolegend.com)
Mitosis is the actual division stage where two daughter cells are created. (biolegend.com)
Mitosis can be further subdivided into prophase, metaphase, anaphase, and telophase as the nucleus undergoes division and chromatids are pulled away from one another. (biolegend.com)
After mitosis, the cell will undergo the G 0 /G 1 phase when the cells rest to become ready for the next round of replication. (biolegend.com)

This development is often immediately followed by the creation of new cells via fission. (fsu.edu)
However, binary fission or prokaryotic fission involves prokaryotic cells wherein the growth of the daughter cell is much like that of the parent cell. (differencebetween.net)
Conversely, binary fission is said to be a simple process of cell division. (differencebetween.net)

Replication and transcription occur in the cell nucleus. (medscape.com)
Thogotoviruses undergo replication and transcription within the cell nucleus. (medscape.com)
Opposite to the mitotic spindle, the separation of chromosomal replication is done through the cell membrane. (differencebetween.net)
They found that MVM sets up replication centers in regions prone to undergoing DNA damage - where cancers can arise. (uwhealth.org)
For additional reagents (including antibodies) on cell cycle analysis or DNA replication, check here . (biolegend.com)
However, it appears that the ability of the In its simplest form, cloning is defined stem cells to transform is limited, except as the exact replication of cells. (who.int)

The nuclei had generally maintained their ovoid shapes, with stippled to hyperchromatic chromatin and fusiform piloid cytoplasm. (ajnr.org)
Arrows indicate dense inclusion bodies as well as its viral factory containing viral crescents in the cell cytoplasm. (cdc.gov)

All other macro- and micronuclei then dissipate, leaving a single nucleus in both cells. (fsu.edu)
Here, we performed single-nucleus RNA-sequencing of ~116,000 nuclei of lungs from 19 COVID-19 decedents who underwent rapid autopsy and 7 control lungs. (cdc.gov)

these are proteins which have undergone keratinization . (wikipedia.org)
Cells depend on their DNA for coding information to make various classes of proteins that include enzymes, certain hormones, transport proteins, and structural proteins that support life. (cdc.gov)
Specialized cell structures called ribosomes are the cellular organelles that actually synthesize the proteins (RNA transcription). (cdc.gov)
Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells. (understandingnano.com)
The polymer shells are developed under mild physiological conditions so as not to alter the chemical structure of the proteins or cause them to clump, preserving their effectiveness on the cancer cells. (understandingnano.com)
Tang's group continues to research ways of more precisely targeting tumors, prolonging the circulation time of the capsules and delivering other highly sought-after proteins to cancer cells. (understandingnano.com)
Like DNA in the nucleus of human cells, archaeal DNA coils around proteins like string wrapped around a yo-yo. (uncommondescent.com)
Also, here's a 2017 Abstract from Nature, noting that "Our results expand the known repertoire of 'eukaryote-specific' proteins in Archaea, indicating that the archaeal host cell already contained many key components that govern eukaryotic cellular complexity. (uncommondescent.com)
When these proteins are turned on (activated) by binding to other molecules, signaling pathways are triggered within cells that promote cell proliferation. (medlineplus.gov)

The mechanisms of immune privilege in human nucleus pulposus (NP) remain unclear. (medsci.org)
A critical role of autophagy was identified in rat nucleus pulposus (NP) cells: Inhibition of autophagy suppresses, while activation of autophagy enhances, the catabolic effect of cytokines. (spandidos-publications.com)
IVDs are composed of two distinct components: The inner gel-like core nucleus pulposus (NP) and the outer firm annulus fibrosus (AF). (spandidos-publications.com)

We already have many examples ure of a discrete action (lever press) to in the sensitivity of nucleus accumbens of how brain biology can affect behav- produce the expected results (cocaine). (lu.se)
Extinction-induced upregula- the work of Sutton et al .3, it has consid- of calcium into nucleus accumbens neu- tion in AMPA receptors reduces cocaine-seeking behaviour. (lu.se)

Each cell (except for red blood cells) contains a nucleus that houses these chromosomes. (cdc.gov)
In plants, polytene chromosomes have been observed in only a few species, and seemed to be restricted to ovary and immature seed tissues, e.g., in Phaseolus coccineus and P. vulgaris (Nagl, 1981), until relatively recently, when they were observed in the cells of the anther tapetum of Vigna unguiculata (Guerra and Carvalheira, 1994) and of some Phaseolus species (Carvalheira and Guerra, 1994). (scielo.br)
1141 The number of nucleoli in a eukaryotic cell nucleus normally is determined by the number of chromosomes with secondary constrictions, or nucleolus organizer regions (NORs). (nanomedicine.com)
However, instead of 10 separate nucleoli, the typical human nucleus contains a single large nucleolus representing the fusion of loops of chromatin from the 10 separate chromosomes with NORs ( Fig. 8.48 ). (nanomedicine.com)

To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form and connectivity. (pasteur.fr)
Scientists from the Institut Pasteur and the CNRS today revealed a new process which allows eliminated cells to temporarily protect their neighbors from cell death, thereby maintaining tissue integrity. (pasteur.fr)
The scientists observed that when the mechanism is deactivated, the simultaneous elimination of several neighboring cells compromises tissue integrity. (pasteur.fr)
Tissue renewal involves the formation of new cells by cell division and the elimination of dead cells. (pasteur.fr)
With the discovery of the polytenics in tapetum tissue, it was observed that in many other species of various angiosperm families the tapetal cells also display polytene, polyploid or both types of nuclei. (scielo.br)
If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
Discriminating between these different models requires biological information about the cells and tissue of the brain at the start of the folding process. (elifesciences.org)
Notably, the pattern of cells and tissue fibers in the cortex had no influence over these mechanical properties and provided no pre-indication of where the sites of folding would occur. (elifesciences.org)
Sample suitability indicates whether this reagent can be used to label already fixed tissue sections or single cells in suspension or cell culture. (biolegend.com)
There can be symmetrical or asymmetrical division depending on the cell and tissue type. (biolegend.com)
Peripheral and tissue Tregs/total CD4+ cell ratio, urinary parameters and renal histology were evaluated for 15 days. (bvsalud.org)
However, a systematic approach is needed to identify the most efficient AAV variants for different cell types, tissue types, and specific targets while avoiding off-target effects, particularly in non-target tissues such as the liver. (lu.se)
The experimental part involves the use of diverse AAV libraries with peptide insert modifications, designed to enhance AAV tropism and enable specific targeting of neuronal and non-neuronal populations in the central nervous system (CNS) and other tissue and cell types. (lu.se)
Tissue samples will be collected from mammalian species, ranging from rodents to non-human primates (NHPs), and subjected to various sequencing methods, including bulk sequencing of tissue samples, 10X single nuclei sequencing, and Parse Bio single nuclei sequencing. (lu.se)
Statistical analysis, visualization, and comparative studies will be performed to evaluate the performance of different AAV variants across various cell types and tissue types. (lu.se)
One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)

The endoreduplication cycle differs from endomitosis because it results in polytene cells (cells with many identical paired chromatids). (scielo.br)
Depending on the behavior of the sister chromatids, polytene nuclei can be divided into two structural types. (scielo.br)

These changes allow cells to grow and divide uncontrollably to form a tumor . (medlineplus.gov)
To divide, cells must duplicate a copy of their DNA, increase mitochondrial density, and assemble/synthesize microtubules during interphase. (biolegend.com)
This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)

Bone marrow examination showed the proliferation of hematopoietic cells were active, mainly granulocytes, and immature granulocytes increased. (frontiersin.org)
The patient underwent a second TSS, and histology of the specimen revealed neoplastic proliferation of astrocytes and spindle-shaped cells with fascicles. (ajnr.org)
Multiple myeloma (MM) is an incurable hematologic malignancy characterized by the clonal proliferation of malignant plasma cells in the bone marrow. (haematologica.org)
Below is a table to aid in reagent choice for cell health and proliferation labeling applications. (biolegend.com)
There are two accepted theories of their origin: remnants of dental lamina and proliferation of cells from the basal layer of oral epithelium into the mandible or maxilla. (bvsalud.org)

these enlarge, eventually fusing into the single large nucleolus characteristic of the interphase human nucleus. (nanomedicine.com)

In order to verify this hypothesis, we treated HTC cells with 1-10 mM Roundup and analysed cellular features by flow cytometry, fluorescence and electron microscopy. (biosafety-info.net)
Although we cannot exclude that other factors than the presence of the herbicide residues could be responsible for the cellular modifications described in GM-fed mice, the concordance of the effects induced by low concentrations of Roundup on HTC cells suggests that the presence of Roundup residues could be one of the factors interfering with multiple metabolic pathways. (biosafety-info.net)
Having multiple nuclei seems to make it easier for bigger cells to properly manage their relatively large cellular bodies. (listverse.com)
The cellular composition of the neurohypophysis is that of specialized glial cells (pituicytes) together with their axons. (ajnr.org)
This mass was resected via a transspenoidal approach, and histology revealed a moderately cellular astrocytomas with compact fibrillated cells in a fascicular pattern. (ajnr.org)
The mechanisms used by certain viruses to dysregulate the host cell through manipulation of epigenetic processes and the role of cellular cofactors such as BRD4 that are known to be involved in epigenetic regulation of host cell pathways will also be covered. (mdpi.com)
Studies in which OPDs were fluorescently labeled proved their localization within the cellular nucleus, increasing the relative efficacy of these species due to their proximity to the DNA target. (umsystem.edu)
Integrated analyses revealed significant alterations in cellular composition, transcriptional cell states, and cell-to-cell interactions, providing insights into the biology of lethal COVID-19. (cdc.gov)

During the recovery phase, the flow of cells from the marrow decreases, with a resultant decrease in the number of neutrophils. (medscape.com)
Lytic NET formation can be observed in neutrophils undergoing cell death, which is referred to as NETosis. (bvsalud.org)

Cryptoglena are consumed by species that are larger in size or that have the ability to increase oral cavity volume or break down cells prior to ingestion, such as those in the phylum amoebozoa. (wikipedia.org)
We are investigating plant species from the Canadian prairie ecological zone by phenotypic cell assays to discover toxins of biological interest. (nih.gov)
Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
When subjected to relatively benign thermal neutrons, the 10B nucleus undergoes a neutron capture reaction forming an excited 11B species. (umsystem.edu)
Ma et al ( 15 ) revealed that compression activated autophagy in NP cells and that compression-induced autophagy was closely associated with intracellular reactive oxygen species production. (spandidos-publications.com)

from the May 12, 2014, issue of The Journal of Cell Biology and includes an interview with senior author Stefano. (scivee.tv)
from the April 14, 2014, issue of The Journal of Cell Biology and includes an interview with authors Dylan Burnette (Vanderbilt University School of. (scivee.tv)
from the February 17, 2014, issue of The Journal of Cell Biology and. (scivee.tv)
from the December 23, 2013, issue of The Journal of Cell Biology and includes an interview with. (scivee.tv)
6 , 7 CXCL12 is an important mediator of several aspects of MM biology including transendothelial migration, 8 , 9 MM plasma cell migration and retention within the bone marrow, 10 , 11 angiogenesis, 7 and osteoclastic bone resorption. (haematologica.org)
Cold Spring Harbor, NY -- Cold Spring Harbor Laboratory Press (CSHLP) announced the release of The Digital Cell: Cell Biology as a Data Science, available on its website in hardcover format. (cshlpress.com)

Previous study has shown that kenaf seed oil extracted by SFE (KSO-SFE) is cytotoxic towards human cervical cancer cell line [ 7 ]. (hindawi.com)
It is an invasive lymphoma derived from NK cells or cytotoxic T cells, which is related to Epstein-Barr virus infection. (frontiersin.org)

The posterior pituitary, being part of the neurohypophysis, harbors specialized glial cells named "pituicytes. (ajnr.org)
The cell harbors, which is undergoing its replicative cycle. (cdc.gov)

Together, these proposals comprise the "microglial priming hypothesis," which predicts that microglia, primed by an existing pathology such as synapse, axon, or neuronal cell body degeneration or by amyloid deposition can be stimulated to an aggressive state of inflammation by secondary influences, such as infection and injury, and during this window of activation can exacerbate neuronal death. (jneurosci.org)

After 7 d of home-cage abstinence, a subset of heroin SA rats ( n = 8) and all yoked-saline controls ( n = 7) were killed for in vitro whole-cell slice electrophysiology. (jneurosci.org)
Another subset of heroin SA rats ( n = 6) underwent a 30 min cue-induced relapse test immediately followed by in vitro whole-cell slice electrophysiology. (jneurosci.org)
5. Carlezon, W.A. Jr. & Wise, R.A. Rewarding actions drug to its receptor, but rather by the rats, treatments associated with aversive of phencyclidine and related drugs in nucleus ac- failure of an expected drug injection to states such as severe drug withdrawal cumbens shell and frontal cortex. (lu.se)

Symptoms result from the selective loss of neurons, mostly in the caudate nucleus and putamen. (medscape.com)
The use of stem cell-derived dopamine neurons or deep brain stimulation (DBS) represents two alternative approaches to treat Parkinson's Disease. (lu.se)
Methods: To express mHTT only in OXT neurons, we used a novel flex-switch adeno-associated viral vector design to selectively express either mHTT or wild-type HTT in the paraventricular nucleus of the hypothalamus using OXT-Cre-recombinase mice. (lu.se)
Conclusions: Our results indicate that mHTT expression can exert cell-autonomous toxic effects on OXT neurons without affecting the non-motor phenotype at early time points in mice. (lu.se)

In response to diverse stimuli, IkBs are rapidly phosphorylated, ubiquitinated and undergo degradation via 26S proteasome. (dtic.mil)
Relying upon a delicate balance between matrix synthesis and degradation, the extracellular matrix (ECM), including collagen and proteoglycans, undergoes a process of remodeling in normal IVDs. (spandidos-publications.com)

By introducing peptide insert modifications into the AAV capsid, the viral vectors can be engineered to target specific cell types and tissues. (lu.se)

Below the plasma membrane of the cell lies the pellicle, a thin cuticle made up of interconnecting strips (16 strips total) that provides protection and support to the cell membrane. (wikipedia.org)
This signal transduction pathway is initiated by epidermal growth factor ligands binding to and activating receptor tyrosine kinases (RTK) at the cell membrane. (hindawi.com)
describe how the phosphoinositides PI(4,5)P2 and PI(3,4,5)P3 control the resulting cell shapes by coordinating actomyosin contractility with plasma membrane expansion. (scivee.tv)
Membrane blebs can help the leading edge of migrating cells protrude forwards, but the contribution of blebs to the motility of Dictyostelium cells is unclear. (scivee.tv)

Here we report that hiPSC can, in a highly autonomous manner, recapitulate spatiotemporally each of the main steps of retinal development observed in vivo and form three-dimensional retinal cups that contain all major retinal cell types arranged in their proper layers. (nature.com)
Other characteristic structures found in paramecia include water-regulating contractile vacuoles, two different types of nuclei, and filamentous trichocysts, which may be involved in defense or extended for anchoring purposes during feeding. (fsu.edu)
There are two types of cell division: sexual cell division and the asexual cell division. (differencebetween.net)
There are two types of cells: the eukaryote cells that contain a nucleus and prokaryote cells that don't have a nucleus. (differencebetween.net)
Although HSPA5 has been implicated in the stress response to environmental injury in several cell types, its role in the glomerular ER stress response is unknown. (bioone.org)
Lung cancer is generally divided into two types, small cell lung cancer and non-small cell lung cancer, based on the size of the affected cells when viewed under a microscope. (medlineplus.gov)
However, one of the challenges in AAV-mediated gene therapy is achieving efficient targeting of specific cell types and tissues. (lu.se)

CXCL12 is a constitutively expressed chemokine which binds primarily to the CXCR4 receptor and regulates cell growth, chemotaxis, myelopoiesis, lymphopoiesis, and development of the nervous and cardiovascular systems. (haematologica.org)

After one dose, individuals with prior infection showed enhanced T cell immunity, antibody secreting memory B cell response to spike and neutralizing antibodies effective against B.1.1.7 and B.1.351. (cdc.gov)

Zinnia cell culture is a unique model system, which at the administration of certain ratio of cytokinins and auxins can be induced to trans-differentiate into vessel elements. (europa.eu)
The have been applied to both the plant and ani- stem cells possess pluripotential charac- mal kingdoms without even stirring a ripple teristics, and can differentiate into various of concern in international conscience [ 2 ]. (who.int)

The mechanisms that regulate the ability of epithelia to maintain their integrity in contexts involving large numbers of eliminated cells remain poorly understood, despite the fact that this situation occurs regularly during embryogenesis or the maintenance of adult tissues. (pasteur.fr)
The AhR canonical genomic signaling pathway occurs as follows: upon ligand binding, the complex undergoes conformational changes and translocates into the nucleus. (invivogen.com)

Tests done on human breast cancer cell lines in laboratory mice showed significant reduction in tumor growth. (understandingnano.com)
Using a cancer-cell-targeting type of virus called Minute Virus of Mice (MVM) as their model system, Majumder and his colleagues developed sequencing-based methods to help them identify the invading virus's preferred zip codes within the nucleus. (uwhealth.org)
Mice underwent a battery of behavioural tests to assess psychiatric and social behaviours 3 months post-injection or at 2 months of age, respectively. (lu.se)

A number of direct and indirect radiation interaction pathways can produce damage to the DNA of irradiated cells. (cdc.gov)

Extraction from 9 parameters of KSO-SFE was screened for cytotoxicity towards human colorectal cancer cell lines (HT29) and mouse embryonic fibroblast (NIH/3T3) cell lines using MTS assay. (hindawi.com)
Human colorectal cancer (HT29) and mouse embryonic fibroblast (NIH/3T3) cell lines were purchased from the American Type Culture Collection (ATCC), USA. (hindawi.com)
We provide the first report of the effects of extracts prepared from the shrub Symphoricarpos occidentalis in several human cell lines. (nih.gov)
The same protective mechanism based on local EGFR-ERK activation was discovered independently in human cell lines by the research group led by Olivier Pertz at the University of Bern in Switzerland (the results are published in the same journal 2 ). (pasteur.fr)
We aimed for addressing the role of FasL expression in human intervertebral disc degeneration (IDD) and immune privilege in terms of the interaction between NP cells and immunocytes via the FasL-Fas machinery. (medsci.org)
The human body has nearly 1013 cells. (cdc.gov)
Most human nuclei contain only one nucleolus, except for liver cell nuclei which may contain more than one nucleolus 935 and cultured HeLa (cancer) cells which may have up to six. (nanomedicine.com)
The human genome contains five NORs per haploid chromosome set, or 10 NORs per diploid nucleus, each located near the tip of a chromosome. (nanomedicine.com)
HT29-Lucia™ AhR cells express the secreted Lucia luciferase reporter gene under the control of a minimal promoter coupled with the human Cyp1a1 gene's entire regulatory sequence, which contains six dioxin-responsive elements (DREs). (invivogen.com)
Finally, IKKβ knockdown was used to further confirm the effect of the NF‑κB signal on human NP cells autophagy, and the data showed that IKKβ knockdown upregulated the autophagy of NP cells during inflammatory conditions. (spandidos-publications.com)
DBS is a widely used FDA-approved treatment and stem cell-derived dopamine neuron replacement has now evolved to the first in-human clinical trials. (lu.se)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)
The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)

specifically, nuclei distinct from skeletal muscle may contribute to these findings. (cdc.gov)

Very much to our surprise, we found that these structures can undergo all sorts of gymnastics," says Luger, a biochemist at the University of Colorado Boulder. (uncommondescent.com)
Therefore, preferential accumulation of 10B-containing structures within cancerous cells can lead to selective destruction of these cells. (umsystem.edu)

Lung cancer is a disease in which certain cells in the lungs become abnormal and multiply uncontrollably to form a tumor . (medlineplus.gov)

While the mechanisms responsible for aberrant plasma cell expression of CXCL12 remain to be determined, studies in other systems suggest a role for hypoxia and hypoxia-inducible transcription factors. (haematologica.org)

The shells, which at about 100 nanometers are roughly half the size of the smallest bacterium, degrade harmlessly in non-cancerous cells. (understandingnano.com)
The process does not present the risk of genetic mutation posed by gene therapies for cancer, or the risk to healthy cells caused by chemotherapy, which does not effectively discriminate between healthy and cancerous cells, Tang said. (understandingnano.com)

In addition, Shen et al ( 14 ) reported that the autophagy of rat AF cells was induced by serum deprivation in vitro and that IL-1β upregulated serum deprivation-induced autophagy in a dose-dependent manner. (spandidos-publications.com)

Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals. (invivogen.com)

Nematodes and many other non-chordate animals seem to have only type VI intermediate filaments , fibers that structure the nucleus . (wikipedia.org)

Our project was focused on the role of IkB kinases IKKalpha, IKKbeta, and IKKepilson IKKepilson is called in the literature also IKKi due to its inducible nature in constitutive activation of NF-kB in prostate carcinoma PB cell lines and PC tumors. (dtic.mil)
Effective immunotherapy of stromal-rich tumors requires simultaneous targeting of cancer cells and immunosuppressive elements of the microenvironment. (aacrjournals.org)

The scientists' observations confirm that tissues need to develop mechanisms preventing the elimination of neighboring groups of cells. (pasteur.fr)
The advantages also include production of one cell type isolated from complexity of leaf tissues, accessibility for chemical manipulations and microscope observations, high potential and synchrony of TE differentiation, preservation of vessel element patterning in similarity to zinnia hypocotyls in vivo. (europa.eu)

The effi- risk of infection - DBS requires battery changes cacy of dopaminergic drug treatment provides a com- with a clear physical and somewhat unsightly pelling rationale for the use of dopamine cell thera- reminder of an intervention, as is evident by pies to restore striatal dopamine neurotransmission. (lu.se)

They are ovoid in shape and are small, with the larger cells being on average 25 x 15 μm. (wikipedia.org)

Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
However, the autophagy induced by TNF‑α and IL‑1β and the corresponding molecular mechanism appear to be cell‑type dependent. (spandidos-publications.com)

In contrast, cyclin A binding to E2F-1 impedes PRMT1 methylation and augments PRMT5 methylation, thus ensuring that E2F-1 is locked into its cell-cycle progression mode. (embl.de)

Under these experimental conditions, the death rate and the general morphology of HTC cells were not affected, as well as most of the cytoplasmic organelles. (biosafety-info.net)

Over-expression of hypoxia-inducible factor in multiple myeloma plasma cells strongly induced in vivo angiogenesis, and administration of a CXCL12 antagonist decreased hypoxia-inducible factor-induced angiogenesis. (haematologica.org)

Therefore, this study determined the cytotoxicity of KSO-SFE on colon cancer cells. (hindawi.com)

Unlike a star, the plasma is highly rarefied (a low pressure gas), so that the proton-proton cycle that powers the sun could not be thus achieved on earth, as it is only the intensely high density of nuclei in the sun's core that allows the process to occur sustainably, and that the plasma is contained within its own gravitational mass, and isolated within the cold vacuum of space. (scitizen.com)
If the demand of cells is high, a shift to the left in the differential count may occur. (medscape.com)
4. They should over time become cheaper to make encing many of the neuropsychiatric and autonomic and easier to deliver, which will facilitate the off target effects that can occur with oral dopamin- switch from DBS surgery to cell implantation. (lu.se)

The hypoxic regulation of CXCL12 was examined in multiple myeloma plasma cell lines using polymerase chain reaction and western blotting. (haematologica.org)

Formation and fusion of TEs into a xylem vessel involves a cascade of processes, including cell division, cell elongation, cell wall synthesis, cell wall material deposition and lignification and, a final step of programmed cell death (PCD). (europa.eu)

This project was focussed on the role and timing of programmed cell death (PCD) in tracheary elements (TEs) formation during the trans-differentiation of mesophyll cells in a model system of Zinnia elegans cell culture. (europa.eu)
Xylem vessels consist of a number of stacked tracheary elements (TEs) that originate through re-differentiation of root and shoot pro-cambium and cambium cells. (europa.eu)

TA muscle was homogenized and prepared for cell death enzyme-linked immunosorbent assay (ELISA), while histomorphology was conducted on transverse sections of the TA muscle mid-belly prepared for terminal dUTP nick-end labeling (TUNEL) and laminin duel immunofluorescence and quantified via standard stereology. (cdc.gov)
RESULTS: Cell death was increased in both old control (-50%) and old SSC-loaded (-105%) skeletal muscle versus young muscle, as quantified by ELISA (p (cdc.gov)
The scientists observed that the activation of the EGFR-ERK pathway protected neighboring cells from cell death for approximately one hour, thereby preventing the simultaneous elimination of a group of cells. (pasteur.fr)
When a large percentage of these organelles malfunction, cells cannot do their jobs-and everything from weakness to death can result. (scientificamerican.com)
In addition, using immunohistochemical staining and quantification of terminal deoxynucleotidyl transferase-mediated biotinylated UTP nick end labeling (TUNEL)-positive and activated caspase-3-positive cell death after intraperitoneal LPS challenges, we addressed the hypothesis that this exaggerated inflammation exacerbates the neurodegenerative process. (jneurosci.org)
Autophagy is involved in the control of cell death ( 8 ). (spandidos-publications.com)

We also collected macrophages and CD8 + T cells from the peripheral blood of patients with IDD for co-cultures with NP cells. (medsci.org)

reveal that blebs form at the front of chemotaxing Dictyostelium cells, particularly when the cells are faced with a mechanically resistant environment, and that this process is guided by a PI3-kinase-dependent signaling pathway. (scivee.tv)
Cells follow a process during cell division. (differencebetween.net)

Radiation can disrupt the structure of the DNA (and other macromolecules), thereby disrupting normal cell and organ functions. (cdc.gov)

Large cell carcinoma encompasses non-small cell lung cancers that do not appear to be adenocarcinomas or squamous cell carcinomas. (medlineplus.gov)

Arrow indicates extracellular-enveloped viruses or cell-associated enveloped particles. (cdc.gov)
That relationship between a virus and its infected host cell is complicated, and new UW Carbone Cancer Center member Kinjal Majumder, PhD , studies how these DNA viruses co-opt the host's machinery for their own benefit. (uwhealth.org)
Is this shared between different tumor viruses and between different cancer cells? (uwhealth.org)

Thogoto virus initially attaches to sialic acid receptors in host cells through glycoproteins. (medscape.com)

Anatomy102

Organisms13

Diseases1

Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Psychiatry and Psychology8

Phenomena and Processes46

Disciplines and Occupations3

Information Science4

Health Care1

Apoptosis11

Subsequently4

Epithelial13

Genes5

Tumor cells5

Electrons4

Nuclear15

Near the nucleus2

Induced plur1

Protein16

Mitosis12

Fission3

Replication6

Cytoplasm2

Single nucleus2

Proteins9

Pulposus3

Accumbens2

Chromosomes4

Tissue17

Chromatids2

Divide3

Proliferation5

Interphase1

Cellular8

Neutrophils2

Species5

Biology6

Cytotoxic2

Harbors2

Pathology1

Rats3

Neurons4

Degradation2

Viral1

Membrane4

Types7

Regulates cell growth1

Antibodies1

Differentiate2

Occurs2

Mice3

Pathways1

Human14

Distinct1

Structures2

Abnormal1

Transcription1

Cancerous cells2

Vitro1

Signals1

Fibers1

Tumors2

Tissues2

Evident1

Ovoid1

Molecular2

Progression1

Morphology1

Vivo1

Colon1

Occur3

Polymerase1

Involves1

Differentiation2

Death6

Macrophages1

Process2

Radiation1

Cancers1

Viruses3

Attaches1