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  • biology
  • These fundamental results could be important to agricultural research and are published in the October 10, 2010, early on-line edition of Nature Cell Biology. (redorbit.com)
  • Understanding these mechanisms of molecular organization is a primary goal of cell biology. (redorbit.com)
  • As co-author David Ehrhardt from Carnegie's Department of Plant Biology explained: "In many cells, microtubule arrays are created with aid of a centralized body called a centrosome. (redorbit.com)
  • The building is intended to look like a cell from the outside and to include an assortment of forms inspired by molecular biology inside. (innovations-report.com)
  • The cell-shaped building attempts to combine the architecture and the biology structures," he said. (innovations-report.com)
  • Phys.org) -A crucial step toward skin cancer may be changes in the genes that control cell shape, report a team of scientists from The Methodist Hospital Research Institute, the Institute of Cancer Research, London, and Harvard Medical School in an upcoming issue of Nature Cell Biology . (phys.org)
  • Medical Xpress)-Scientists have discovered genes that control shape changes in melanoma skin cancer cells, allowing them to wriggle free and spread around the body, according to new research published in Nature Cell Biology. (phys.org)
  • The study of cells is called cell biology. (wikipedia.org)
  • According to the Royal Society, her study of the fruit fly's embryonic nervous system "has led to new insights into the biology of neural stem cells, and the ability of neurons to regenerate after damage. (wikipedia.org)
  • Escherichia
  • By growing filamentous Escherichia coli cells in doughnut-shaped microchambers, we find that the cells recovered their straight, native rod-shaped morphologies when released from captivity at a rate consistent with the theoretical prediction. (pasteur.fr)
  • populations
  • We still saw three distinct shapes other than rounded and elongated, and a handful of cell populations enriched with intermediate shapes-a lot of possibilities for hypothesis generation. (phys.org)
  • Time series modeling is performed on each cell individually, making the approach broadly useful for analyzing asynchronous cell populations. (rsc.org)
  • Neural
  • Neural tube cells in Xenopus apically constrict during the initial invagination as well as during hingepoint folding. (wikipedia.org)
  • Moreover, Brand "identified a novel role for a key regulator in cell division in controlling the strength of neuronal connections," which "could help uncover new drug targets in the search for treatments for neural disorders such as Parkinson's and Huntington's disease. (wikipedia.org)
  • Neural stem cells divide in a self-renewing manner, generating daughter cells that give rise to different types of neurons. (wikipedia.org)
  • dynamics
  • As the use of live-cell imaging continues to increase, new computational procedures are needed to characterize and classify the temporal dynamics of individual cells. (rsc.org)
  • isotropic
  • based their modelling on the plausible assumption that apical and basal surfaces of epithelial cells both tend towards isotropic shapes as the most energy-efficient ('relaxed') packing solution to differential curvature. (cam.ac.uk)
  • When the authors modelled cells that had near-isotropic shapes on both the inner and outer surfaces of tubes, they found topological differences between the inner and outer surfaces that required the cells to be scutoid. (cam.ac.uk)
  • The authors then confirmed this finding using a mechanical model of the outer surface, in which the lengths of cell-cell interfaces were minimized, encouraging isotropic shapes. (cam.ac.uk)
  • In that case, the stress fiber assembly is isotropic, and these fibers can pull on their surroundings in an isotropic fashion, and consequently the resulting cell shape is isotropic (without a preferred alignment). (wikipedia.org)
  • Long-axis division contributes to the formation of isotropic cell shapes within the monolayer. (wikipedia.org)
  • walls
  • The following measurements were taken of contiguous runs of cells, Including only one of the walls of the outer two cells of a run. (dave-cushman.net)
  • The measurements were made on the face of the plaster which was pared down with a scalpel to expose the cell walls. (dave-cushman.net)
  • Cell walls may or may not be present. (wikipedia.org)
  • They are devoid of cellulosic cell walls, chloroplasts or stigmata. (wikipedia.org)
  • nucleus
  • Ehrhardt continued: "In centrosomal arrays, these nucleating complexes are recruited to the centrosome, where they give rise to a star-shaped array centered near the nucleus. (redorbit.com)
  • Most important among these is a cell nucleus, an organelle that houses the cell's DNA. (wikipedia.org)
  • The nucleus typically lies in the posterior half of the cell. (wikipedia.org)
  • differential
  • Here, we probe the effects of mechanical strain on cell shape by modelling the mechanical strains caused by bending and differential growth of the cell wall. (pasteur.fr)
  • But the authors realized that, when epithelia form tubes and so curve in only one orientation, or form egg shapes that also have differential surface curvature, the cells' inner and outer surfaces can contact different neighbours. (cam.ac.uk)
  • outer
  • Second, in the current model, the authors used 2D modelling of the inner and outer surfaces of cells to infer 3D cell shapes - predictions might differ if modelling was extended to cell shapes that are explicitly 3D. (cam.ac.uk)
  • Interior cells of the blastoderm move towards the outer cells, thus "intercalating" with each other. (wikipedia.org)
  • In position-dependent Hippo signaling, where the outer and inner cells are polar and nonpolar respectively, AMOT and AMOTL2 are essential for Hippo pathway activation and appropriate cell fate specification. (wikipedia.org)
  • distinct
  • Under normal conditions, each hemocyte was found to take on just one of five distinct shapes about 98 percent of the time. (phys.org)
  • Several sea urchins, however, including the sand dollars, are oval in shape, with distinct front and rear ends, giving them a degree of bilateral symmetry. (wikipedia.org)
  • chromosomes
  • While the chromosomes are drawn to each side of the cell, the non-kinetochore spindle fibers push against each other, in a ratcheting action, that stretches the cell into an oval. (wikipedia.org)
  • form
  • The researchers identified seven genes that cause cells to take on an especially rounded form, or else an elongated form. (phys.org)
  • It is possible for 3D shapes resembling frusta to form tubes. (cam.ac.uk)
  • Together, the main purpose of these cells is to form a protective layer for the more specialized cells below. (wikipedia.org)
  • Rather, their irregular shapes help them to interlock with each other like puzzle pieces to form a sturdy layer. (wikipedia.org)
  • Briefly, it has been supposed that cells, once seeded, form focal adhesions on top of the ridges and not above the grooves. (wikipedia.org)
  • Epithelial cells connect to one another via their lateral membranes to form epithelial sheets that line cavities and surfaces throughout the animal body. (wikipedia.org)
  • Mitotic septins (Cdc3, Cdc10, Cdc11, Cdc12, Shs1) form a ring structure at the bud neck during cell division. (wikipedia.org)
  • Chlorodendrales scales are unique from other Prasinophyceae lineages because the scales fuse to form a theca, which acts as an exterior protective casing for the cell. (wikipedia.org)
  • Cells are typically found as individuals, but have been seen in the form of pairs and tetrads. (wikipedia.org)
  • This response may be a primitive form of sexual interaction, similar to the more well-studied bacterial transformation that is also associated with DNA transfer between cells leading to homologous recombinational repair of DNA damage. (wikipedia.org)
  • The PDZ-binding motif of angiomotin serves as a protein recognition site and deletion of as few as three amino acids from the C-terminal results in complete loss of pro-migratory activity, and endothelial cells expressing such mutant angiomotin failed to migrate or form tubes. (wikipedia.org)
  • living organism
  • We found that by altering the way the cells are grown to better mimic conditions in a living organism , gene expression could have a profound impact on cell shape," said Zheng Yin, the paper's lead author and a postdoctoral fellow at the Department of Systems Medicine and Bioengineering of The Methodist Hospital Research Institute (TMHRI). (phys.org)
  • researchers
  • My new friend leaned forward and said, in a tone that fell somewhere between conspiratorial and accusatory, "Hey, I read the other day that, using imaging, researchers found the most basic of cells, the glue that holds life together. (photonics.com)
  • Evidence is mounting that researchers can both maintain stem cells in the undifferentiated state, and determine the direction of their fate, by precise control of the surface features beneath them. (youris.com)
  • Using automated high content screening and sophisticated computational modeling, the researchers' screening and analysis of tens of millions of genetically manipulated cells helped them identify more than a dozen genes that influence cell shape. (phys.org)
  • The researchers name this 3D cell shape scutoid, from the Latin word for shield. (cam.ac.uk)
  • Researchers have shown that the removal of bottle cells does not inhibit gastrulation, but simply makes it less efficient. (wikipedia.org)
  • species
  • While the number of cells in plants and animals varies from species to species, humans contain more than 10 trillion (1013) cells. (wikipedia.org)
  • Cell shape and size of Chlorodendrales cells varies depending on the species. (wikipedia.org)
  • The cells range greatly in size from species to species, with an upper limit of ~25m in length. (wikipedia.org)
  • Thecate features vary greatly from species to species, in which thecae can vary between 1-5 scale layers, in scale shape, in scale size, and in molecular composition/ultrastructure. (wikipedia.org)
  • The specific mechanism depends on the species, the cell type, and the morphogenetic movement. (wikipedia.org)
  • apically
  • In some epithelial cells, PIP2 is apically localised while PIP3 is basolaterally localised. (wikipedia.org)
  • During Xenopus gastrulation, bottle cells are located in the dorsal marginal zone and apically constrict inwards to initiate involution of the blastopore. (wikipedia.org)
  • Cytoplasmic
  • Inside the cell is the cytoplasmic region that contains the genome (DNA), ribosomes and various sorts of inclusions. (wikipedia.org)
  • Stem Cell Res
  • Scientists from the Institute of Stem Cell Research and the Institute of Experimental Genetics at the Helmholtz Zentrum M√ľnchen (HMGU) examined the effects of Twist1 activation on breast epithelial cells, paying particular attention to the duration of the Twist1-signal. (eurekalert.org)
  • Stem cells respond to the stiffness, chemistry and topography of the environments they find themselves in -- and scientists building their understanding of the complex signalling controlling these responses hope to harness this knowledge to take stem cell research further. (youris.com)
  • found
  • It was found that cells without vimentin are extremely delicate when disturbed with a micropuncture). (wikipedia.org)
  • With the blocking of transport of LDL-derived cholesterol inside the cell, cells were found to store a much lower percentage of the lipoprotein than normal cells with vimentin. (wikipedia.org)