Cell AgingCyclin-Dependent Kinase Inhibitor p16Telomerebeta-GalactosidaseAging, PrematureCyclin-Dependent Kinase Inhibitor p21TelomeraseTumor Suppressor Protein p53AgingBiological ProcessesTelomere ShorteningFibroblastsCells, CulturedDNA DamageCell ProliferationOxidative StressRetinoblastoma ProteinReactive Oxygen SpeciesSignal TransductionApoptosisCell Line, TumorPlant LeavesCell CycleEndothelial CellsTOR Serine-Threonine KinasesPhenotypeRNA InterferenceRNA, Small InterferingDown-RegulationCell DivisionUp-RegulationGene Expression RegulationCell LineBlotting, WesternStem CellsHistonesTime Factorsp38 Mitogen-Activated Protein KinasesCell Cycle ProteinsReverse Transcriptase Polymerase Chain ReactionDNA-Binding ProteinsMice, KnockoutMice, Inbred C57BLChlorophyllGene Expression Regulation, PlantEthylenesGene Expression Regulation, NeoplasticEndothelium, VascularCell DifferentiationFlow CytometryTumor Suppressor Protein p14ARFAtherosclerosisLongevityBiological MarkersTransfectionCell Cycle CheckpointsCell Transformation, NeoplasticPhosphorylationArabidopsisRNA, MessengerPlant Growth RegulatorsTumor Suppressor ProteinsDose-Response Relationship, DrugImmunohistochemistryEnzyme ActivationSirtuin 1Plant ProteinsFlowersPlants, Genetically ModifiedArabidopsis ProteinsCytokininsPetuniaras ProteinsDiploidyNeoplasmsMutationTelomeric Repeat Binding Protein 2Nuclear ProteinsModels, BiologicalCyclopentanesHydrogen PeroxideProgeriaOxylipinsCell Line, TransformedPlant StemsDarknessCyclin-Dependent Kinase Inhibitor p15Transcription FactorsGenes, rasForeskinGene Knockdown TechniquesGenes, p16Gene Expression ProfilingRepressor ProteinsAlstroemeriaOncogenesReproductionProtein-Serine-Threonine KinasesHCT116 CellsWerner Syndrome