Disease is commonly induced by injecting filtrates of propagable tumors into newborn mice. (lookformedical.com)
Mammary1
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. (academicinfluence.com)
Membrane1
The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. (lookformedical.com)
Antigens2
Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. (lookformedical.com)
The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. (lookformedical.com)
Type2
Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor. (academicinfluence.com)
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. (academicinfluence.com)
Gene2
External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. (lookformedical.com)
Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. (lookformedical.com)
Human1
Proteins synthesized by HUMAN IMMUNODEFICIENCY VIRUSES such as the HIV-1 and HIV-2 . (lookformedical.com)
Endogenous4
Serological characterization of C-type retroviruses endogenous to the C57BL/6 mouse and isolated in tumours induced by radiation leukaemia virus (RadLV-Rs). (microbiologyresearch.org)
Different serotypes of B-tropic murine leukemia viruses and association with endogenous ecotropic viral loci. (microbiologyresearch.org)
Serological characterization of B-tropic viruses of C57BL mice: possible origin by recombination of endogenous N-tropic and xenotropic viruses. (microbiologyresearch.org)
Radiation-induced murine leukemias and endogenous retroviruses: the time course of viral expression. (microbiologyresearch.org)
Malignant1
Oral administration in domestic cats causes malignant hepatomas and tumors of the esophagus and kidney. (nih.gov)
Characterization2
PMID- 214398 TI - Characterization of an adenosine triphosphatase of the avian myeloblastosis virus and the virus-infected myeloblast. (nih.gov)
Characterization of sera from different stages of tumour growth. (nih.gov)
Tumours1
At least 10 antibody specificities were detected on the 13 tumours investigated, allowing separation of the MAbs into three classes: (i) those recognizing the autologous tumour, heterologous tumours as well as normal thymic tissue, (ii) those specific for the autologous tumour, and (iii) those specific for one tumour, but not ones of autologous origin. (microbiologyresearch.org)
Antibodies3
We examined whether specific antigenicities, viral or cellular, were expressed by tumour cells that could be recognized by antibodies from the irradiated animals. (microbiologyresearch.org)
The present findings suggest that the detection of immune complexes in unfractionated samples of late tumour-bearer serum using a C1q-binding assay is masked by the increasing production of tumour-specific antibodies and by a shift from complement fixing to non-complement-fixing tumour-specific antibodies. (nih.gov)
PMID- 214407 TI - Antibodies to Herpes simplex virus types 1 and 2 in patients with squamous-cell carcinoma of uterine cervix in India. (nih.gov)
Vitro3
The reactivity of such MAbs towards thymoma cell lines established in vitro was investigated by means of an ELISA. (microbiologyresearch.org)
AB - Peripheral blood mononuclear cells from donors of known serological status with respect to EB virus were exposed to the virus in vitro and then cultured at various cell concentrations. (nih.gov)
The results strongly suggest that the regression phenomenon is an in vitro expression of long-term T-cell-mediated immunity to EB virus which the large majority, if not all, infected individuals possess. (nih.gov)
Radiation2
She went back home and they said, after that, that that radiation virus turned out to be a virus. (nih.gov)
Stevenson: Before we get started on that, maybe we could go back in time and kind of pick up where Bob Huebner got started with virus cancer type investigations. (nih.gov)
And up until I knew Bob from the Cancer Institute, I had been at the Public Health Service in Cincinnati and knew him more in terms of Adenoviruses and a variety of enteric viruses which his laboratory had been very instrumental in discovering, developing and, in fact, he supplied us with Adenovirus Type 3, which we used in disinfection studies and things like that. (nih.gov)
AB - Antibody activity to Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) was measured by the indirect hemagglutination (IHA) test in sera from 124 women with squamous-cell carcinoma of the uterine cervix, 46 women with non-cervical cancer and 116 matched normal women. (nih.gov)
National Cancer Institute 1 Introduction 1 Clinical investigations 3 Origins of the cancerous state 4 Development of clinical cancer 5 Autonomy 5 Spread of cancer 6 Wound washings 6 Cancer cells in circulating blood 7 Spread of tumor in animal models. (nih.gov)
Transformation2
I. Complete regression of virus-induced transformation in cultures of seropositive donor leukocytes. (nih.gov)
Transformation by subgenomic fragments of Rous sarcoma virus DNA. (wikidata.org)
Lines3
All cultures from nine seronegative adult and 12 foetal donors gave rise to cell lines following subculture 4 weeks post infection. (nih.gov)
In contrast, seropositive donor cultures seeded at the higher cell concentrations developed foci of proliferating EBNA-positive cells within the first 1--2 weeks but thereafter regressed completely and subcultures made after 4 weeks never gave rise to cell lines. (nih.gov)
Rosette-forming human lymphoid cell lines. (wikidata.org)
Time4
We were doing work on enteric viruses in water and sewage and, at that time, I was also collecting fecal specimens from Albert Sabin's polio vaccine experiments to determine what quantities of Poliovirus were in feces, and we were using his vaccine strains in his volunteers as some indication of what you could find in raw feces. (nih.gov)
Do you recall when Bob got interested in tumor viruses for the first time? (nih.gov)
They were ubiquitous and they hung around for a long time and they had qualities that some of the other DNA viruses he was aware of did not. (nih.gov)
Well, it was right about that time that Charlotte Friend came up with her virus. (nih.gov)
Friend1
Huebner: Was that the Friend virus that she was talking about? (nih.gov)