ApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Inhibitor of Apoptosis ProteinsProto-Oncogene Proteins c-bcl-2DNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinCell Line, TumorApoptosis Inducing FactorCell SurvivalCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsSignal TransductionCaspase 8MitochondriaTumor Suppressor Protein p53Fas Ligand ProteinEnzyme ActivationCells, CulturedCytochromes cTumor Cells, Culturedbcl-X ProteinAnnexin A5Cell ProliferationBlotting, WesternAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsCell LineFlow CytometryProto-Oncogene ProteinsCell CycleAntineoplastic AgentsPoly(ADP-ribose) PolymerasesEnzyme InhibitorsTNF-Related Apoptosis-Inducing LigandReactive Oxygen SpeciesTime FactorsJurkat CellsTransfectionCell DivisionRNA, Small InterferingCaspase 7HL-60 CellsDown-RegulationDose-Response Relationship, DrugMembrane Potential, MitochondrialCell DeathTumor Necrosis Factor-alphaGenes, bcl-2PhosphorylationNecrosisMembrane Glycoproteinsbcl-2 Homologous Antagonist-Killer ProteinCytochrome c GroupUp-RegulationRNA, MessengerMyeloid Cell Leukemia Sequence 1 ProteinDNA DamageBH3 Interacting Domain Death Agonist ProteinReverse Transcriptase Polymerase Chain ReactionNF-kappa BProto-Oncogene Proteins c-aktMice, Inbred C57BLStaurosporineGene Expression Regulation, NeoplasticImmunohistochemistrybcl-Associated Death ProteinAntineoplastic Agents, PhytogenicCeramidesCarrier ProteinsReceptors, TNF-Related Apoptosis-Inducing LigandProtein-Serine-Threonine KinasesMice, KnockoutOxidative StressHeLa CellsCaspase 2Drug SynergismNeoplasm ProteinsGene Expression RegulationFas-Associated Death Domain ProteinCysteine EndopeptidasesRNA InterferenceApoptotic Protease-Activating Factor 1Diagnostic Tests, RoutineMitogen-Activated Protein KinasesMembrane ProteinsGene ExpressionEpithelial CellsDNA-Binding ProteinsModels, BiologicalReceptors, Tumor Necrosis FactorCell NucleusMutationMice, NudeCaspase 1U937 Cells