src Homology DomainsTyrosineCell ProliferationSignal TransductionPhosphorylationProtein Tyrosine PhosphatasesMolecular Sequence DataSequence Homology, Amino AcidCell DivisionAmino Acid SequenceCells, CulturedProtein BindingCell LineProtein Tyrosine Phosphatase, Non-Receptor Type 11Adaptor Proteins, Signal TransducingPhosphotyrosineProtein Tyrosine Phosphatase, Non-Receptor Type 6Base Sequencesrc-Family KinasesRecombinant Fusion ProteinsPhosphoproteinsCell Line, TumorTransfectionBinding SitesEnzyme ActivationIntracellular Signaling Peptides and ProteinsApoptosisCloning, MolecularRecombinant ProteinsProto-Oncogene ProteinsProto-Oncogene Proteins pp60(c-src)Protein-Tyrosine KinasesRNA, MessengerBlotting, WesternCell DifferentiationCell CycleGRB2 Adaptor ProteinMutationTyrosine 3-MonooxygenaseSequence AlignmentCarrier ProteinsDNA-Binding ProteinsTumor Cells, CulturedSH2 Domain-Containing Protein Tyrosine PhosphatasesCell MovementSequence Homology, Nucleic AcidProteinsMembrane ProteinsProto-Oncogene Proteins c-fynTranscription FactorsMutagenesis, Site-DirectedDNAAmino Acid MotifsPhosphatidylinositol 3-KinasesProtein Structure, TertiaryMice, Inbred C57BLGene Expression RegulationDNA, ComplementaryKineticsCell SurvivalReceptor Protein-Tyrosine KinasesLymphocyte Activation3T3 CellsImmunohistochemistryEnzyme InhibitorsReceptor, Epidermal Growth FactorGene ExpressionDNA PrimersDown-RegulationPhospholipase C gammaT-LymphocytesBromodeoxyuridineReverse Transcriptase Polymerase Chain ReactionPrecipitin TestsMice, KnockoutRNA, Small InterferingProtein ConformationLymphocyte Specific Protein Tyrosine Kinase p56(lck)Models, BiologicalDose-Response Relationship, DrugModels, MolecularTime FactorsProto-Oncogene Proteins c-ablShc Signaling Adaptor ProteinsProtein Interaction Domains and MotifsNuclear ProteinsStructure-Activity RelationshipFibroblastsPeptide FragmentsLigandsGenes, srcImmunoblottingCell AdhesionTranscription, GeneticMitogen-Activated Protein KinasesTrans-ActivatorsCell Transformation, NeoplasticGlutathione TransferaseEpidermal Growth FactorProto-Oncogene Proteins c-akt