Cell ProliferationCell DivisionCells, CulturedCell CycleCell Line, TumorSignal TransductionApoptosisCyclin-Dependent KinasesCell DifferentiationCyclin-Dependent Kinase 2PhosphorylationBromodeoxyuridineCyclin-Dependent Kinase 4RNA, MessengerCell LineCell SurvivalCell MovementBlotting, WesternCyclin-Dependent Kinase Inhibitor p27Cyclin-Dependent Kinase 5Proliferating Cell Nuclear AntigenImmunohistochemistryCyclin D1CyclinsCell Cycle ProteinsLymphocyte ActivationTumor Cells, CulturedMice, Inbred C57BLRNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionKi-67 AntigenGene Expression Regulation, NeoplasticCDC2-CDC28 KinasesDown-RegulationG1 PhaseCell Growth ProcessesProtein-Serine-Threonine KinasesGene Expression RegulationTransfectionMice, KnockoutFlow CytometryEpithelial CellsCyclin-Dependent Kinase Inhibitor p21Dose-Response Relationship, DrugCyclin-Dependent Kinase 6Time FactorsT-LymphocytesStem CellsFibroblastsTranscription FactorsRNA InterferenceGene ExpressionS PhaseMolecular Sequence DataProto-Oncogene ProteinsCyclin EMice, TransgenicUp-RegulationMice, NudeEnzyme ActivationThymidineEnzyme InhibitorsProto-Oncogene Proteins c-aktCDC2 Protein KinaseMitosisCell CountMuscle, Smooth, VascularTumor Suppressor ProteinsCell Transformation, NeoplasticMice, Inbred BALB CDNA-Binding ProteinsDNANuclear ProteinsGrowth InhibitorsHyperplasiaMutationProto-Oncogene Proteins c-mycCyclin DGene Knockdown TechniquesBase SequenceRats, Sprague-DawleyAntineoplastic AgentsExtracellular Signal-Regulated MAP KinasesMitogensModels, BiologicalProtein BindingMyocytes, Smooth MuscleGene Expression Regulation, DevelopmentalTumor Suppressor Protein p53Breast NeoplasmsMAP Kinase Signaling SystemPhenotypeMitogen-Activated Protein Kinase 3Recombinant ProteinsAmino Acid SequenceMitogen-Activated Protein Kinase 1Transcription, GeneticTransforming Growth Factor betaDisease Models, AnimalPhosphatidylinositol 3-Kinases