Cell AgingCell ProliferationCell DivisionFibroblastsCells, CulturedErythrocyte AgingCell CycleSignal TransductionCell Line, TumorApoptosisCell LineCyclin-Dependent Kinase Inhibitor p16Anion Exchange Protein 1, ErythrocyteCyclin-Dependent Kinase Inhibitor p21RNA, Messengerbeta-GalactosidaseTumor Suppressor Protein p53Blotting, WesternGene Expression RegulationCell DifferentiationAgingRNA, Small InterferingTransfectionBromodeoxyuridinePhosphorylationUp-RegulationDown-RegulationTelomereDNA DamageCell Cycle ProteinsRNA InterferenceGene ExpressionCell Cycle CheckpointsDiploidyFlow CytometryCell MovementCell SurvivalTime FactorsTumor Suppressor ProteinsPhenotypeRetinoblastoma ProteinImmunohistochemistryDNATranscription FactorsDNA-Binding ProteinsProliferating Cell Nuclear AntigenCell NucleusMolecular Sequence DataCell Transformation, NeoplasticLymphocyte ActivationProtein-Serine-Threonine KinasesNuclear ProteinsHeterochromatinMice, Inbred C57BLTelomeraseKi-67 AntigenReverse Transcriptase Polymerase Chain ReactionCyclinsNeoplasmsTumor Cells, CulturedGene Expression Regulation, NeoplasticBase SequenceCell Growth ProcessesModels, BiologicalCyclin-Dependent KinasesOxidative StressEpithelial CellsDose-Response Relationship, DrugMice, KnockoutTranscription, GeneticCyclin D1T-LymphocytesReactive Oxygen SpeciesStem CellsProtein BindingThymidineMice, NudeMice, TransgenicHistonesProto-Oncogene Proteins c-aktPromoter Regions, GeneticCell CountDNA ReplicationMuscle, Smooth, VascularCaveolin 1Cyclin-Dependent Kinase Inhibitor p27Mice, Inbred BALB CCaveolinsBiological MarkersEnzyme ActivationHyperplasiaGrowth InhibitorsEnzyme InhibitorsLongevityHydrogen PeroxideExtracellular Signal-Regulated MAP KinasesMyocytes, Smooth MuscleRats, Sprague-DawleyMitogensGene Knockdown Techniques