Cell CycleCell ProliferationCell Cycle ProteinsCell DivisionProtein-Serine-Threonine KinasesPhosphatidylinositol 3-KinasesMAP Kinase Signaling SystemApoptosisSignal TransductionCell Line, TumorProtein KinasesCells, CulturedPhosphorylationCell Cycle CheckpointsG1 PhaseProtein Kinase InhibitorsCell LineCell DifferentiationMitosisRNA, MessengerCalcium-Calmodulin-Dependent Protein KinasesBlotting, WesternS PhaseCyclin-Dependent Kinase Inhibitor p27Cyclinssrc-Family KinasesCDC2 Protein KinaseMitogen-Activated Protein Kinase 1Cell SurvivalTumor Cells, CulturedMolecular Sequence DataBromodeoxyuridineCyclin-Dependent Kinase Inhibitor p21TransfectionProtein Kinase CMitogen-Activated Protein Kinase 3p38 Mitogen-Activated Protein KinasesMutationGene Expression RegulationTime FactorsProto-Oncogene ProteinsFlow CytometryDNA-Binding ProteinsRNA, Small InterferingDown-RegulationTranscription FactorsCyclin-Dependent KinasesProtein-Tyrosine KinasesCyclin-Dependent Kinase 2CDC2-CDC28 KinasesImmunohistochemistryBase SequenceCyclic AMP-Dependent Protein KinasesMitogen-Activated Protein Kinase KinasesExtracellular Signal-Regulated MAP KinasesReverse Transcriptase Polymerase Chain ReactionRetinoblastoma ProteinCyclin D1Cell MovementProto-Oncogene Proteins c-aktDose-Response Relationship, DrugProtein BindingEnzyme ActivationGene Expression Regulation, NeoplasticProliferating Cell Nuclear AntigenJNK Mitogen-Activated Protein KinasesG2 PhaseMice, Inbred C57BLFibroblastsMitogen-Activated Protein KinasesNuclear ProteinsModels, BiologicalAmino Acid SequenceTumor Suppressor Protein p53Enzyme InhibitorsDNAGene ExpressionTumor Suppressor Proteinsp21-Activated KinasesMice, KnockoutCell NucleusCyclin-Dependent Kinase 4RNA InterferenceTranscription, GeneticUp-RegulationKineticsG0 PhaseAntineoplastic AgentsHeLa CellsEpithelial CellsMAP Kinase Kinase KinasesRecombinant ProteinsLymphocyte ActivationCell Growth ProcessesKi-67 AntigenCyclin EG1 Phase Cell Cycle CheckpointsIntracellular Signaling Peptides and ProteinsReceptor Protein-Tyrosine KinasesDNA Replication