Cell ProliferationCell DivisionCells, CulturedSignal TransductionCell Line, TumorApoptosisCell CycleCell DifferentiationK562 CellsBromodeoxyuridineRNA, MessengerCell SurvivalCell LineCell MovementImmunohistochemistryBlotting, WesternProliferating Cell Nuclear AntigenLymphocyte ActivationMice, Inbred C57BLPhosphorylationKi-67 AntigenReverse Transcriptase Polymerase Chain ReactionRNA, Small InterferingTumor Cells, CulturedGene Expression Regulation, NeoplasticDown-RegulationCell Growth ProcessesDose-Response Relationship, DrugGene Expression RegulationEpithelial CellsFlow CytometryMice, KnockoutT-LymphocytesTime FactorsTransfectionCyclin D1Stem CellsGene ExpressionProto-Oncogene Proteins c-aktMice, TransgenicUp-RegulationMice, NudeThymidineFibroblastsRNA InterferenceMuscle, Smooth, VascularTranscription FactorsCell CountCyclin-Dependent Kinase Inhibitor p27Mice, Inbred BALB CEnzyme InhibitorsMolecular Sequence DataCell Transformation, NeoplasticDNARats, Sprague-DawleyEnzyme ActivationCell Cycle ProteinsHyperplasiaBase SequencePhosphatidylinositol 3-KinasesProto-Oncogene ProteinsGrowth InhibitorsGene Knockdown TechniquesExtracellular Signal-Regulated MAP KinasesMyocytes, Smooth MuscleDNA-Binding ProteinsMitogensAntineoplastic AgentsProto-Oncogene Proteins c-mycCyclin-Dependent Kinase Inhibitor p21Gene Expression Regulation, DevelopmentalMAP Kinase Signaling SystemModels, BiologicalPhenotypeMitogen-Activated Protein Kinase 3Protein-Serine-Threonine KinasesRecombinant ProteinsBreast NeoplasmsG1 PhaseDisease Models, AnimalMitogen-Activated Protein Kinase 1MutationPlatelet-Derived Growth FactorCell AdhesionFibroblast Growth Factor 2Nuclear ProteinsGrowth SubstancesMitogen-Activated Protein KinasesNeovascularization, PathologicInterleukin-2Transforming Growth Factor betaTumor Suppressor ProteinsS PhaseGene Expression ProfilingMitosisTumor Suppressor Protein p53Mitotic IndexH(+)-K(+)-Exchanging ATPaseTranscription, GeneticEpidermal Growth Factor