HeLa CellsCell ProliferationCell DivisionCells, CulturedApoptosisSignal TransductionCell Line, TumorCell CycleRNA, MessengerCell DifferentiationCell LineCell SurvivalBromodeoxyuridineTransfectionMolecular Sequence DataBlotting, WesternPhosphorylationCell MovementBase SequenceRNA, Small InterferingImmunohistochemistryProliferating Cell Nuclear AntigenTumor Cells, CulturedGene Expression RegulationReverse Transcriptase Polymerase Chain ReactionTranscription FactorsLymphocyte ActivationDown-RegulationGene Expression Regulation, NeoplasticMice, Inbred C57BLCell NucleusKi-67 AntigenDNADNA-Binding ProteinsDose-Response Relationship, DrugRNA InterferenceTime FactorsFlow CytometryGene ExpressionTranscription, GeneticCell Growth ProcessesThymidineNuclear ProteinsEpithelial CellsMice, KnockoutMitosisT-LymphocytesAmino Acid SequenceUp-RegulationFibroblastsCyclin D1Mice, NudeEnzyme ActivationStem CellsCell Cycle ProteinsMutationProtein BindingPromoter Regions, GeneticMice, TransgenicProto-Oncogene Proteins c-aktEnzyme InhibitorsRecombinant ProteinsCell CountProtein-Serine-Threonine KinasesMice, Inbred BALB CCyclin-Dependent Kinase Inhibitor p27Gene Knockdown TechniquesMuscle, Smooth, VascularProto-Oncogene ProteinsCell Transformation, NeoplasticAntineoplastic AgentsKineticsGrowth InhibitorsG1 PhaseModels, BiologicalCyclin-Dependent Kinase Inhibitor p21Extracellular Signal-Regulated MAP KinasesProto-Oncogene Proteins c-mycS PhaseHyperplasiaRecombinant Fusion ProteinsPhenotypeRats, Sprague-DawleyMAP Kinase Signaling SystemCell AdhesionTumor Suppressor Protein p53Myocytes, Smooth MuscleMitogen-Activated Protein Kinase 3MitogensDNA PrimersNeoplasm ProteinsGene Expression Regulation, DevelopmentalTrans-ActivatorsMitogen-Activated Protein Kinase 1Membrane ProteinsDNA ReplicationCarrier ProteinsTumor Suppressor ProteinsBreast NeoplasmsFluorescent Antibody Technique