Cell ProliferationHCT116 CellsCell DivisionCells, CulturedCell Line, TumorSignal TransductionApoptosisCell CycleCell DifferentiationBromodeoxyuridineRNA, MessengerCell SurvivalCell MovementCell LineBlotting, WesternImmunohistochemistryPhosphorylationProliferating Cell Nuclear AntigenTumor Cells, CulturedLymphocyte ActivationMice, Inbred C57BLReverse Transcriptase Polymerase Chain ReactionGene Expression Regulation, NeoplasticRNA, Small InterferingKi-67 AntigenDown-RegulationCell Growth ProcessesFlow CytometryDose-Response Relationship, DrugTransfectionGene Expression RegulationEpithelial CellsMice, KnockoutT-LymphocytesTime FactorsCyclin D1Stem CellsUp-RegulationGene ExpressionThymidineMice, NudeMice, TransgenicFibroblastsTranscription FactorsProto-Oncogene Proteins c-aktRNA InterferenceCell CountMuscle, Smooth, VascularCyclin-Dependent Kinase Inhibitor p27Colonic NeoplasmsMice, Inbred BALB CMolecular Sequence DataCell Cycle ProteinsEnzyme ActivationAntineoplastic AgentsCell Transformation, NeoplasticCyclin-Dependent Kinase Inhibitor p21Enzyme InhibitorsDNAHyperplasiaTumor Suppressor Protein p53Gene Knockdown TechniquesProto-Oncogene ProteinsDNA-Binding ProteinsExtracellular Signal-Regulated MAP KinasesGrowth InhibitorsRats, Sprague-DawleyProtein-Serine-Threonine KinasesProto-Oncogene Proteins c-mycMyocytes, Smooth MuscleMitogensG1 PhaseBase SequenceMAP Kinase Signaling SystemGene Expression Regulation, DevelopmentalMutationMitogen-Activated Protein Kinase 3PhenotypeBreast NeoplasmsNuclear ProteinsModels, BiologicalDisease Models, AnimalMitogen-Activated Protein Kinase 1MitosisS PhaseCell AdhesionPhosphatidylinositol 3-KinasesNeovascularization, PathologicPlatelet-Derived Growth FactorCyclinsRecombinant ProteinsFibroblast Growth Factor 2Tumor Suppressor ProteinsGrowth SubstancesTransforming Growth Factor betaGene Expression ProfilingMitogen-Activated Protein KinasesInterleukin-2Neoplasm Proteinsbeta Catenin