Cell ProliferationCell DivisionCell Line, TumorCells, CulturedApoptosisSignal TransductionCell SurvivalCell CycleBlotting, WesternFlow CytometryLymphocyte ActivationT-LymphocytesReverse Transcriptase Polymerase Chain ReactionTumor Cells, CulturedGene Expression Regulation, NeoplasticCell LineDose-Response Relationship, DrugImmunohistochemistryMice, NudeMice, Inbred BALB CRNA, MessengerRNA, Small InterferingAntineoplastic AgentsTransfectionDown-RegulationMolecular Sequence DataGene ExpressionRecombinant ProteinsAmino Acid SequenceBreast NeoplasmsCell DifferentiationEnzyme-Linked Immunosorbent AssayCattleRecombinant Fusion ProteinsCell MovementBromodeoxyuridineMice, Inbred C57BLPhosphorylationCell Growth ProcessesEpithelial CellsProliferating Cell Nuclear AntigenFibroblastsTime FactorsGene Expression RegulationKi-67 AntigenStem CellsCell CountThymidineProto-Oncogene Proteins c-aktUp-RegulationMitogensRNA InterferenceMice, TransgenicInterleukin-2Growth InhibitorsMice, KnockoutTranscription FactorsEnzyme InhibitorsTetrazolium SaltsCyclin D1Gene Knockdown TechniquesInterferon-gammaCell Culture TechniquesCytokinesBase SequenceCD4-Positive T-LymphocytesDisease Models, AnimalDNAXenograft Model Antitumor AssaysPhenotypeRats, Sprague-DawleyGrowth SubstancesCell AdhesionTransforming Growth Factor betaPlatelet-Derived Growth FactorMuscle, Smooth, VascularMutationCyclin-Dependent Kinase Inhibitor p27B-LymphocytesFibroblast Growth Factor 2Neoplasm InvasivenessAntigens, CDEndothelium, VascularEndothelial CellsDrug SynergismAntibodies, MonoclonalLymphocytesLeukocytes, MononuclearCell Transformation, NeoplasticModels, BiologicalNeoplasm ProteinsNeovascularization, PathologicCulture Media, Serum-FreeEnzyme ActivationVascular Endothelial Growth Factor ASpleenHyperplasiaGene Expression ProfilingCell Cycle ProteinsReal-Time Polymerase Chain Reaction