Cell DeathCell ProliferationApoptosisCell DivisionCells, CulturedSignal TransductionCell Line, TumorCause of DeathCell SurvivalCell CycleCell DifferentiationCell LineCaspasesBlotting, WesternRNA, MessengerBromodeoxyuridineMice, Inbred C57BLImmunohistochemistryTumor Cells, CulturedPhosphorylationDeathTime FactorsRNA, Small InterferingCaspase 3Cell MovementReverse Transcriptase Polymerase Chain ReactionDose-Response Relationship, DrugIn Situ Nick-End LabelingFlow CytometryEnzyme ActivationMice, KnockoutTransfectionLymphocyte ActivationProto-Oncogene Proteins c-bcl-2Down-RegulationGene Expression Regulation, NeoplasticGene Expression RegulationProliferating Cell Nuclear AntigenNecrosisUp-RegulationEpithelial CellsKi-67 AntigenMice, TransgenicGene ExpressionRNA InterferenceEnzyme InhibitorsT-LymphocytesDNA FragmentationCell Growth ProcessesProto-Oncogene ProteinsMolecular Sequence DataFibroblastsAntineoplastic AgentsCell CountProto-Oncogene Proteins c-aktTranscription FactorsMice, NudeTumor Suppressor Protein p53MutationMitochondriaStem CellsRats, Sprague-DawleyModels, BiologicalReactive Oxygen SpeciesMice, Inbred BALB CCyclin D1DNA-Binding ProteinsAutophagyProtein-Serine-Threonine Kinasesbcl-2-Associated X ProteinDisease Models, AnimalNeuronsThymidineDNACell Cycle ProteinsBase SequenceExtracellular Signal-Regulated MAP KinasesCell Transformation, NeoplasticGene Expression Regulation, DevelopmentalMuscle, Smooth, VascularPhenotypeCyclin-Dependent Kinase Inhibitor p27NeoplasmsGene Knockdown TechniquesNuclear ProteinsCaspase InhibitorsCyclin-Dependent Kinase Inhibitor p21MAP Kinase Signaling SystemAntigens, CD95Mitogen-Activated Protein KinasesRecombinant ProteinsBreast NeoplasmsProto-Oncogene Proteins c-mycMembrane ProteinsCell NucleusApoptosis Regulatory ProteinsAmino Acid SequenceMitosisGrowth InhibitorsPhosphatidylinositol 3-Kinases