2023TissuesTumorDisordersInvoluntary movementsPrecursorsProliferationMembraneStem cellsUncontrollableNucleusMusclesEmbryonicMigrationMoleculesGenesSickle cellMembranesTypicallyNerve cells in the brainMigrateCellularOccurFlashcardsAbstractDiluteAsymmetricAbnormalAffectsBiolPhysiologyBasalNerves2022DorsalGeneCancerMidlineCytoplasmNuclear movementBrainVitroContractionDirectly observeSolar cellsBehaviorMesodermMicroscopicMechanicalSpinalGeneticPatternsResearchersProteinQuartzEmbryoClosureBoneNutrientsMarginalProteins
20232
- Oct. 27, 2023 The most lethal feature of any cancer is metastasis, the spread of cancer cells throughout the body. (sciencedaily.com)
- Methods Cell Biol;175: 33-43, 2023. (bvsalud.org)
Tissues6
- New research reveals the mechanics behind how breast cancer cells may invade healthy tissues. (sciencedaily.com)
- T lymphocytes were more enriched in the gingiva than the PDL, yet in both tissues, the relative fraction of the γδT cells was higher than the αβ T cells. (huji.ac.il)
- Sickle cell disease (SCD) is an inherited disorder of red blood cells (RBCs) caused by a mutation in the beta globin gene resulting in an abnormal hemoglobin (HbS) that causes RBCs to sickle under certain conditions 2 and impairs the delivery of oxygen to tissues. (lww.com)
- A new study led by University of Minnesota Twin Cities researchers shows that the stiffness of protein fibers in tissues like collagen, is a key component in controlling the movement of cells. (studentdigitalus.org)
- Sliced or fragmented tissues are used to observe ciliary movements in thick human airway tissues . (bvsalud.org)
- The new method enables microscopic observation of ciliary movements without slicing or fragmenting the airway tissues . (bvsalud.org)
Tumor7
- When cancer cells dissociate from the original tumor and migrate via the blood stream to colonize distant organs, is the main cause of cancer death. (news-medical.net)
- Mutations in the cell adhesion molecule known as integrin alpha 7 (integrin 7) lead to unchecked tumor cell proliferation and a significantly higher incidence in cancer spread, or metastasis, in several cancer cell lines, report researchers at the University of Pittsburgh School of Medicine in a study published in the Journal of the National Cancer Institute. (news-medical.net)
- Many corporations work like tumor cells for the relentless destruction of the environment. (truthout.org)
- The financial industry, chemical industry, drug companies, nuclear industrial complex and dirty energy empire work "like tumor cells for the relentless destruction of the environment that they themselves depend upon for their very lives. (truthout.org)
- Is GCT (Giant Cell Tumor) Cancerous? (medicinenet.com)
- Giant cell tumors (GCTs) are a type of bone tumor. (medicinenet.com)
- The tumor may cause stiffness or limited movement in the affected joint if it is located near a joint. (medicinenet.com)
Disorders10
- Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly - a form of mental retardation - result from abnormal migration of nerve cells during the development of the brain. (news-medical.net)
- Diagnosis and assessment of Parkinson disease and other movement disorders. (medlineplus.gov)
- Other movement disorders. (medlineplus.gov)
- The goal of this project is to elucidate cellular and circuit dysfunctions underlying hypokinetic, hyperkinetic, and dystonic movement disorders in Parkinson´s Disease and L-DOPA-induced dyskinesia. (lu.se)
- There's a great gathering of great minds and movement disorders. (medscape.com)
- Just to highlight a few key things that came up: I was really excited to see some representation around nonmotor issues in movement disorders and specifically, in Parkinson's disease . (medscape.com)
- Manganese (Mn) toxicity is characterized by movement disorders resembling Parkinson's disease. (cdc.gov)
- What's new concerning Parkinson's disease and other movement disorders? (medscape.com)
- These clinical abstracts are courtesy of the organization WeMove (Worldwide Education and Awareness for Movement Disorders). (medscape.com)
- WeMove produced these summaries on the basis of the data presented at the 8th International Congress of Parkinson's Disease and Movement Disorders, held in Rome, Italy, June 14-17, 2004. (medscape.com)
Involuntary movements6
- Involuntary movements like tremors or tics result from issues with the nerves or muscles. (healthline.com)
- What are the types of involuntary movements? (healthline.com)
- There are several types of involuntary movements. (healthline.com)
- What causes involuntary movements? (healthline.com)
- What drugs cause involuntary movements? (healthline.com)
- These are the most common cause of drug-induced involuntary movements. (healthline.com)
Precursors4
- The morphogenetic movements of gastrulation rearrange the three germ layers precursors, positioning mesodermal cells between outer ectodermal and inner endodermal cells to shape the head-to-tail body axis. (nature.com)
- We demonstrate how left-right signals affect the behavior of zebrafish somite cell precursors by using live imaging and fate mapping studies in dand5 homozygous mutants compared to wildtype embryos. (unl.pt)
- Flagellar root contraction and nuclear movement in Chlamydomonas may be causally related to signaling of induction of flagellar precursor genes or to the transport of flagellar precursors or their messages to sites of synthesis or assembly near the basal apparatus of the cell. (rupress.org)
- Giant cell tumors (GCTs) arise from cells called osteoclast precursors. (medicinenet.com)
Proliferation2
- We have also developed interests in other pathways which regulate gene transcription and cancer cell proliferation in response to stress and changes in cell metabolism. (southampton.ac.uk)
- Role of CtBP transcriptional repressors in cancer cell proliferation and survival In common with p53, CtBP1 and CtBP2 proteins were discovered through their physical association with a viral oncoprotein. (southampton.ac.uk)
Membrane8
- This movement may have a role in transport of the beta granule from Golgi to B-cell membrane. (diabetesjournals.org)
- It is also important to understand that diffusion is quite often how molecules move in and out of our cells through the cell membrane. (backnotes.com)
- Osmosis is the net movement of water molecules from a region of high-water potential (dilute solution) to a region of low-water potential (concentrated solution) through a partially permeable membrane. (backnotes.com)
- Active transport is the movement of particles through a partially permeable membrane from a region of lower concentration to a region of higher concentration using energy from respiration. (backnotes.com)
- The separation of charges influences the movement of ions across the membrane. (biologyonline.com)
- There are integral membrane proteins called transporters that mediate movement of molecules that are too polar or too large to move across a membrane by diffusion. (biologyonline.com)
- Actin contributes to biological processes such as sensing environmental forces, internalizing membrane vesicles, moving over surfaces, and dividing the cell in two. (wustl.edu)
- The basic principles of this local control are illustrated in the images below and are outlined as follows: First, an anatomic barrier exists between perilymph and endolymph, and it consists of Reissner membrane, the stria vascularis, and the reticular lamina formed by tight junctions between the apices of hair cells and the adjacent supporting cells (see the image above). (medscape.com)
Stem cells5
- Scientists have identified a distinct subpopulation of cancer stem cells (CSCs) that is responsible for metastasis of a deadly human pancreatic cancer. (news-medical.net)
- Researchers have shown that bone marrow stem cells injected into a damaged inner ear can speed hearing recovery after partial hearing loss. (news-medical.net)
- Using this method on embryonic stem cells led to the development of transgenic mice with targeted genes knocked out. (wikipedia.org)
- In recognition of their discovery of how homologous recombination can be used to introduce genetic modifications in mice through embryonic stem cells, Mario Capecchi, Martin Evans and Oliver Smithies were awarded the 2007 Nobel Prize for Physiology or Medicine. (wikipedia.org)
- So far, they have made huge steps forward and will hopefully continue to do so in their quest to solve paralysis, by teaming up with 'associate faculty based in departments across KSOM and the University to study stem cell-driven new medicine', Dr. Liu and his team at USC are determined to keep researching stem cells and much more! (medicalkidunya.com)
Uncontrollable4
- An involuntary movement occurs when you move your body in an uncontrollable and unintended way. (healthline.com)
- In some cases, uncontrollable movements in one or more areas of your body may quickly subside. (healthline.com)
- People with TD often exhibit uncontrollable repetitive facial movements. (healthline.com)
- Different types of prescription and illicit drugs may cause uncontrollable movements as side effects. (healthline.com)
Nucleus6
- When Chlamydomonas cells are deflagellated by pH shock or mechanical shear the nucleus rapidly moves toward the flagellar basal apparatus at the anterior end of the cell. (rupress.org)
- During flagellar regeneration the nucleus returns to a more central position within the cell. (rupress.org)
- The nucleus is connected to the flagellar apparatus by a system of fibers, the flagellar roots (rhizoplasts), which undergo a dramatic contraction that coincides with anterior nuclear movement. (rupress.org)
- Reporting in the journal Biochemical and Biophysical Research Communications (BBRC), bioengineering researchers at UC San Diego published videos of a key message-carrying protein called paxillin moving abruptly from hubs of communication and transportation activity on the cell surface toward the nucleus. (news-medical.net)
- The centrosome normally stayed at the most apical side, apart from the nucleus, in the neuroepithelial cell during the S to G2 phase, while the Pax6 mutant showed unstable movement of the centrosome associated with an abnormal INM. (elsevierpure.com)
- Robert Brown, originator of Brownian movement and the cell nucleus, in research by Brian J Ford. (brianjford.com)
Muscles3
- While some signals from the brain still get through, they are not strong enough to trigger activity in the motor neurons that control movement of the muscles. (ideaspies.com)
- They report how they sought to restore such movement by stimulating the sensory neurons of the muscles that communicate directly with the motor neurons of the limb. (ideaspies.com)
- To help prevent damage to hair cells, the muscles in the middle ear contract to decrease the movement of the ossicles caused by loud noises, This response to loud noises is called the acoustic reflex. (msdmanuals.com)
Embryonic1
- We explore the method on three circuits for haematopoiesis and embryonic stem cell development for commitment and reprogramming scenarios and illustrate how the method can be used to determine sequential steps for onsets of external factors, essential for efficient reprogramming. (lu.se)
Migration4
- A number of diseases like cancer and autoimmune diseases, such as multiple sclerosis and arthritis, involve the inappropriate migration of cells," says Professor McColl. (sciencedaily.com)
- Our research shows that these receptors which help the cells migrate can be blocked pharmacologically, preventing the cell migration which causes the disease. (sciencedaily.com)
- The embryo of the frog Xenopus laevis is widely used as a model of cell polarization, migration, and morphogenesis due to its unique experimental advantages. (nature.com)
- Johns Hopkins researchers have found a way to directly observe cell migration -- in real time and in living tissue. (news-medical.net)
Molecules2
- Diffusion is essentially the movement of molecules from a region of higher concentration to a region of lower concentration as a result of thermal motion. (biologyonline.com)
- Specifically, diffusion is the mechanism of movement of oxygen, nutrients and other molecules across the capillary walls and the movement of other molecules across membranes. (biologyonline.com)
Genes3
- In other situations the response is cell cycle arrest or programmed cell death (apoptosis), providing a barrier to further tumour development that the tumour may ultimately circumvent through the acquisition of a mutation in one of the genes within the stress-response pathway. (southampton.ac.uk)
- Early methods to target genes to certain sites within a genome of an organism (called gene targeting) relied on homologous recombination (HR). By creating DNA constructs that contain a template that matches the targeted genome sequence it is possible that the HR processes within the cell will insert the construct at the desired location. (wikipedia.org)
- Genes to Cells , 12 (9), 983-996. (elsevierpure.com)
Sickle cell8
- FDA approves 2 gene therapies for sickle cell. (abc4.com)
- Anemia and sickle cell anemia before surgery are often unrecognized medical comorbidities that can and should be addressed. (lww.com)
- Sickle cell anemia occurs in 1 in 365 Black births and 1 in 16,300 Hispanic births, with 100,000 Americans currently living with sickle cell anemia. (lww.com)
- Patients who have anemia or sickle cell anemia are at increased risk for postoperative complications, including the need for blood transfusions and delayed healing. (lww.com)
- For those with sickle cell disease, surgeries can precipitate a sickle cell crisis. (lww.com)
- There should also be careful consideration and monitoring of the pain level of patients with sickle cell anemia in the perioperative period. (lww.com)
- Individuals with SCD often have anemia (sickle cell anemia). (lww.com)
- The sickle cell gene is most commonly found in individuals from areas where malaria is endemic, given that the trait (one sickle gene and one normal gene) can be protective against the disease. (lww.com)
Membranes1
- Cell membranes are partially permeable so cells absorb or remove water via osmosis. (backnotes.com)
Typically3
- For the purposes of this article I will call this kata "heian shodan" (as per Gichin Funakoshi's renaming of the form) and I will focus on movement typically found in Funakoshi's Shotokan system. (wayofleastresistance.net)
- To record eye movements, research institutions typically use a so-called eye tracker - a sensor technology in which infrared light is projected onto the retina, reflected, and eventually measured. (mpg.de)
- Giant cell tumors typically affect young and middle-aged adults and are more common in women than in men. (medicinenet.com)
Nerve cells in the brain2
- It affects nerve cells in the brain and spinal cord, causing nerves in the muscle to die. (cdc.gov)
- ALS, also known as Lou Gehrig's disease, is a rapidly progressive, fatal neurological disease that affects nerve cells in the brain and spinal cord, causing muscle nerves to die and affecting voluntary muscle movement. (cdc.gov)
Migrate2
- Led by Professor of Immunology Shaun McColl, the researchers have identified molecular "receptors" on the surface of cells which are involved in helping cells migrate to sites where they can cause disease. (sciencedaily.com)
- We describe a population of cells in the vicinity of the LRO, named Non-KV Sox17:GFP+ Tailbud Cells (NKSTCs), which migrate anteriorly and contribute to future somites. (unl.pt)
Cellular5
- The furry ( fry ) gene encodes an evolutionarily conserved protein with a wide variety of cellular functions, including cell polarization and morphogenesis in invertebrates. (nature.com)
- Examples include exposure to toxic compounds or radiation, loss of contact with other cells or the extra-cellular matrix, lack of oxygen (hypoxia), acidic pH, the activation of oncogenes, induction of cellular senescence, oxidative damage or depletion of essential metabolites. (southampton.ac.uk)
- CtBP activity is modified by UV radiation and glycolytic metabolism, suggesting that CtBPs regulate cell survival in response to cellular stress. (southampton.ac.uk)
- Starting with single cells, Simi BioCell's capabilities extend as far as studying the entire cellular development of a complete complex organism. (simi.com)
- Histopathologic findings exhibited here, revealed a cellular phenomenon known as the transmigration of inflammatory cells, which explained the movement of antibodies into the intestinal lumen. (cdc.gov)
Occur4
- The constant random movement of particles (and their kinetic energy) allows diffusion to occur. (backnotes.com)
- The amount of material crossing a surface per unit of time is called flux and depends upon the difference in concentrations between two compartments where movement is potentially going to occur. (biologyonline.com)
- Giant cell tumors (GCTs) are benign (noncancerous) tumors that most commonly occur in the bones of the arms and legs. (medicinenet.com)
- Abnormal and sometimes strange postures may occur because of these movements. (medlineplus.gov)
Flashcards1
- Study Movement Of Substances In And Out Of Cells using smart web & mobile flashcards created by top students, teachers, and professors. (brainscape.com)
Abstract1
- abstract = "The mechanism by which the adsorbent guanidinium affects the open-circuit photovoltage of dye-sensitized TiO2 nanocrystalline solar cells was investigated. (edu.au)
Dilute1
- however, these patients can be optimized using preoperative red blood cell transfusions to dilute sickle cells and elevate the hemoglobin level. (lww.com)
Asymmetric1
- Cell polarization is essential during gastrulation, driving asymmetric cell division, cell movements, and cell shape changes. (nature.com)
Abnormal2
- The abnormal movement may be reduced or disappear during sleep. (medlineplus.gov)
- Sometimes two conditions (such as a brain injury and medicine) interact to cause the abnormal movements when neither one alone would cause a problem. (medlineplus.gov)
Affects5
- Loss of Fry function drastically affects the movement and morphological polarization of cells during gastrulation and disrupts dorsal mesoderm convergent extension, responsible for head-to-tail elongation. (nature.com)
- A particular interest of our work has been how HDM2 and HDMX protein synthesis is controlled in response to cell-signalling pathways in different cell types, and how this affects p53 function in these cells. (southampton.ac.uk)
- The mechanism by which the adsorbent guanidinium affects the open-circuit photovoltage of dye-sensitized TiO 2 nanocrystalline solar cells was investigated. (edu.au)
- This type of involuntary movement most often affects the hands and arms. (healthline.com)
- This affects voluntary muscle movement. (cdc.gov)
Biol1
- J Cell Biol (1987) 105 (4): 1799-1805. (rupress.org)
Physiology1
- Stress-response pathways play a key role in the patho-physiology and treatment of many diseases, including cancer.At almost every stage of the development of a tumour, cells are exposed to some form of stress. (southampton.ac.uk)
Basal2
- From live observation using cultured cortical slices from the Pax6 mutant rat, we identified the premature descent of S phase cells, the unsteady ascent or descent of G2 phase cells, and ectopic cell division within the basal side of the ventricular zone (VZ). (elsevierpure.com)
- The phrase lives of a cell refers to the independent yet interrelated parts of a human cell including mitochondria, centrioles, and basal bodies that once led independent lives. (cdc.gov)
Nerves2
- In general, involuntary movement suggests damage to nerves or areas of your brain that affect motor coordination. (healthline.com)
- Vibrations of the cilia make the hair cells send signals through nerves to the brain. (msdmanuals.com)
20221
- 13, 2022 Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to new research. (sciencedaily.com)
Dorsal2
- At the beginning of Xenopus gastrulation, the presumptive anterior mesoderm cells located at the dorsal marginal zone (DMZ) roll inward at the midline of the blastopore lip in a process called involution. (nature.com)
- Gastrulation movements are orchestrated by a small, heterogeneous group of cells with inductive and morphogenetic properties located in the dorsal lip of the blastopore (DBL) of the amphibian gastrula known as the Spemann-Mangold organizer or dorsal organizer. (nature.com)
Gene1
- Many current and prospective treatments for cancer work by either inhibiting, or re-activating stress response pathways.Our work focuses on the role of regulators of gene transcription in the response of cancer cells to stress. (southampton.ac.uk)
Cancer10
- Researchers are finding new ways to block the movement of cells in the body which can cause autoimmune diseases and the spread of cancer. (sciencedaily.com)
- They are also in the process of identifying receptors on the surface of metastatic cancer cells. (sciencedaily.com)
- In the late 1990s work from a number of groups, including Blaydes et al , demonstrated that HDM2 could be targeted in cancer cells to re-activate the p53 stress-response pathway. (southampton.ac.uk)
- We have undertaken a series of projects examining how HDM2, and its paralogue HDMX is regulated in cancer cells (see Phillips et al, 2010, 2008, 2007, 2006a, 2006b and Phelps et al 2005, 2003). (southampton.ac.uk)
- In a report in Developmental Cell, the scientists say their advance could lead to strategies for controlling both normal growth and the spread of cancer, processes that depend on the programmed, organized movement of cells across space. (news-medical.net)
- The U.S. National Science Foundation-funded discovery could have a major impact on fields that study cell movement, from regenerative medicine to cancer research. (studentdigitalus.org)
- However, the activation states of RhoA are poorly defined in cancer cells. (nih.gov)
- In this study, we examined both the expression levels and the activation states of RhoA in various lung cancer cells by quantitative real-time reverse transcriptase-polymerase chain reaction and in vivo Rho guanine nucleotide exchange assay, respectively. (nih.gov)
- Our results suggest that RhoA is activated in various lung cancer cells independent of its expression levels, and the high activation state of RhoA in SCLC cells mainly depends on a neuroendocrine peptide autocrine system which signals through Galpha12 coupled GPCR to RhoA. (nih.gov)
- This study provides new insights into RhoA signaling in lung cancer cells and may help in developing novel therapeutic strategies against lung cancer. (nih.gov)
Midline1
- We show that NKSTCs originate in a cluster of cells aligned with the midline, posterior to the LRO, and leave that cluster in a left-right alternating manner, primarily from the left side. (unl.pt)
Cytoplasm3
- To study the mechanism of insulin release, we examined β-granule movement in the cytoplasm of monolayer-cultured B-cells. (diabetesjournals.org)
- This is when the cytoplasm shrinks due to the loss of water but the cell wall fails to shrink due to its tough structure. (backnotes.com)
- The cytoplasm eventually tears away from the cell wall. (backnotes.com)
Nuclear movement3
- Flagellar root contraction and nuclear movement during flagellar regeneration in Chlamydomonas reinhardtii. (rupress.org)
- Nuclear movement and flagellar root contraction and extension are not sensitive to inhibitors of protein synthesis (cycloheximide), or drugs that influence either microtubules (colchicine) or actin-based microfilaments (cytochalasin D). Detergent-extracted cell models contract and extend their flagellar roots and move their nuclei in response to alterations of free calcium levels in the medium. (rupress.org)
- Cycles of nuclear movement in detergent-extracted models require ATP to potentiate the contractile mechanism for subsequent calcium-induced contraction. (rupress.org)
Brain5
- Researchers from the University of Pittsburgh and Carnegie Mellon University note that a stroke can lead to disruption of connections between the brain and spinal cord regions that control arm and hand movements. (ideaspies.com)
- Researchers from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the Kavli Institute for Systems Neuroscience in Trondheim have now developed software that uses artificial intelligence to directly predict eye position and eye movements from MRI images. (mpg.de)
- The authors successfully cultured the endothelial cells that come from the barrier and grew them on a transwell support to create an artificial model for the blood-brain barrier. (the-scientist.com)
- which are the transmissions of messages from the brain to muscle groups to create movement. (medicalkidunya.com)
- The hair cells initiate nerve impulses that tell the brain which way the head is moving so that appropriate action can be taken to maintain balance. (msdmanuals.com)
Vitro2
- AST-OPC1 cells come from donated eggs that are fertilized in vitro (ie. (medicalkidunya.com)
- Mn accumulates in the inner ear (cochlea) following acute in vivo treatment and in vitro studies show that uM levels of Mn damage sensory hair cells and spiral ganglion neurons (SGN) in the inner ear. (cdc.gov)
Contraction1
- Involution follows bottle cell contraction and spreads laterally and ventrally leading to the formation of the blastopore, a ring of involuting cells that encircles the yolky vegetal endoderm cells. (nature.com)
Directly observe1
- However, conventional methods to directly observe ciliary movements uses transmitted light , which requires translucent samples. (bvsalud.org)
Solar cells1
Behavior1
- The process of gastrulation is linked to determination of mesodermal cell fates, such that patterning of tissue fates and patterning of cell behavior are interconnected. (nature.com)
Mesoderm1
Microscopic2
- Acquisition is based on microscopic video recordings of cell development. (simi.com)
- Microscopic observation of human airway ciliary movement using wheat germ agglutinin. (bvsalud.org)
Mechanical3
- In the oral mucosa, mechanical stress, either naturally induced by masticatory forces or externally via mechanical loading during orthodontic tooth movement (OTM), is translated, in part, by T cells to alveolar bone resorption. (huji.ac.il)
- Collectively, our data suggest that γδT cells are essential in OTM for translating orthodontic mechanical forces to bone resorption, required for relocating the tooth in the alveolar bone. (huji.ac.il)
- The protein actin forms filaments that provide cells with mechanical support and driving forces for movement. (wustl.edu)
Spinal2
- The process began in April where Dr. Liu injected 10 million AST-OPC1 cells directly into Kris' cervical spinal cord. (medicalkidunya.com)
- Kris recovered two spinal chord levels which made a huge difference in his movement abilities. (medicalkidunya.com)
Genetic1
- Depicting developmental processes as movements in free energy genetic landscapes is an illustrative tool. (lu.se)
Patterns1
- The method opens up rapid and cost-effective research and diagnostic possibilities, for example, in neurological diseases that often manifest as changes in eye-movement patterns. (mpg.de)
Researchers2
- Researchers at the University of California, San Diego (UCSD) School of Medicine have developed new technology which, combined with proteomics, the large-scale study of the structure and function of proteins and their functions, has allowed them to map an extensive network of the signaling proteins that control cell movement. (news-medical.net)
- University of Florida researchers have revealed how the inhaled form of anthrax paralyzes the body's defenses and prevents immune cells from reaching the site of infection. (news-medical.net)
Protein2
- Primary tumors can spread towards distant organs as single cells, when they lose a protein called E-cadherin. (news-medical.net)
- Moreover, we dissected the signaling pathway from the cell surface receptors to RhoA using a broad-spectrum G protein coupled receptor (GPCR) antagonist, [D-Arg1,D-Trp5,7,9,Leu11]Substance P (SP), and a recently reported Galphaq/11-selective inhibitor, YM-254890. (nih.gov)
Quartz1
- They are the most powerful quartz movements on the market today, and they were designed to solve one of the primary assembly problems that confronts everyone making larger clocks-hour and minute hand spacing! (clockparts.com)
Embryo1
- In order to break the initial "egg shape" of the embryo, cells need to polarize in a precise and coordinated manner. (nature.com)
Closure1
- ISLAMABAD: Caretaker Prime Minister Justice (rtd) Mir Hazar Khan Khoso took notice of the reports in the media regarding closure of the Polio Cell in the Prime Minister's Secretariat, Sunday, June 2. (dawn.com)
Bone3
- Nevertheless, despite being considered critical for OTM, depletion of CD4 + and CD8 + T cells is reported to have no impact on tooth movement, thus questioning the function of αβT cells in OTM-associated bone resorption. (huji.ac.il)
- Although giant cell tumors are benign, they can cause problems if they press on nearby structures or grow and weaken the bone to the point of fracture . (medicinenet.com)
- These cells break down and resorb bone tissue during normal bone remodeling. (medicinenet.com)
Nutrients3
- For example, the diagram below demonstrates a cell surrounded by nutrients (red dots). (backnotes.com)
- We can see that on the left, there are a lot more nutrients outside the cell than inside the cell. (backnotes.com)
- For example, what if a cell wanted to absorb extra nutrients from outside the cell despite having a higher concentration of those nutrients inside the cell? (backnotes.com)
Marginal2
- These enzymes are located within the marginal cells of the stria and the underlying spiral ligament. (medscape.com)
- Their function is assisted by a Na + /Cl - /K + cotransporter located in the marginal cells. (medscape.com)
Proteins1
- Some Example Projects: Regulation of HDM2 and HDMX proteins The HDM2 oncoprotein is the major negative regulator of p53 function in the cell. (southampton.ac.uk)