Cell ProliferationEnergy MetabolismGlycolysisCells, CulturedLipid MetabolismSignal TransductionGlucoseCell Line, TumorModels, BiologicalApoptosisMetabolic Networks and PathwaysCell SurvivalCell DivisionCellsCell DifferentiationCell LineRNA, MessengerLactic AcidLiverCitric Acid CycleNeoplasmsGene Expression RegulationMitochondriaMice, Inbred C57BLAdenosine TriphosphateTime FactorsOxidative PhosphorylationGene Expression ProfilingBlotting, WesternDose-Response Relationship, DrugReverse Transcriptase Polymerase Chain ReactionOxidation-ReductionMice, KnockoutCell CycleKineticsPhosphorylationCellular StructuresMolecular Sequence DataMetabolismFibroblastsTOR Serine-Threonine KinasesMetabolomicsMutationHomeostasisCarbonOxygen ConsumptionGene ExpressionMice, TransgenicUp-RegulationT-LymphocytesPyruvate KinaseDown-Regulation2,3-DiphosphoglycerateTumor Cells, CulturedGene Expression Regulation, NeoplasticRNA, Small InterferingTranscription FactorsLymphocyte ActivationFlow CytometryFatty AcidsMycoplasma hyorhinisBromodeoxyuridineEnzyme InhibitorsImmunohistochemistryInsulinOxygenOligonucleotide Array Sequence AnalysisCell MovementCell HypoxiaGlutaminePyruvic AcidPhenotypeReactive Oxygen SpeciesCell Transformation, NeoplasticEnzymesOxidative StressTranscription, GeneticProto-Oncogene Proteins c-aktInsulin-Secreting CellsLactatesCell RespirationCulture MediaProtein-Serine-Threonine KinasesEnzyme ActivationBase SequenceHypoxia-Inducible Factor 1, alpha SubunitDNAAutophagyBiological TransportDiphosphoglyceric AcidsKi-67 AntigenRats, Sprague-DawleyNADPAMP-Activated Protein KinasesProtein BindingAntineoplastic AgentsCarbon IsotopesProliferating Cell Nuclear AntigenStem CellsCalcium